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The map label for this gene is kdgR [H]

Identifier: 119715887

GI number: 119715887

Start: 1754606

End: 1755379

Strand: Direct

Name: kdgR [H]

Synonym: Noca_1652

Alternate gene names: 119715887

Gene position: 1754606-1755379 (Clockwise)

Preceding gene: 119715883

Following gene: 119715892

Centisome position: 35.19

GC content: 74.29

Gene sequence:

>774_bases
GTGGACCTGCCGGGGGACGAGAGCGCGGACCTGGACACCGTGCTGGGCAAGGCGGTGACGATGCTGCGTGCCTTCACCGT
CGACGACCAGGTGCTCTCGTTGGCCGAGCTGGTCCGCCGCACCGGCCTGGCCAAGGCGACCGTGCACCGGGTCGCGGGGG
ACCTGGTCGACAATCGCCTGCTCGACCGCACCGCGCTCGGCTATCGCCTCTCCGGGGGGCTCTTCGAGCTCGGGATGCGC
GCGTCGCTGGAGCGCGGACTGCTCGAGCTGGCGATGCCGTTCCTGCAGGACCTCTACGAGCGGACCCACGAGACCGTCCA
CCTCGGGCTACGGGAGGGTCACGACGTCGTCTACGTCGCCAAGATCGGCGGCCATCGACAGGCGGCCGCCCCCTCCCGGA
CCGGCGGCCGGATGCCGGTGCACTGCACCGCGATCGGCAAGGCCCTGCTCGCCCACGCCGACGCCGCCGTGCAGCGCGAG
GTGCTGAGCGGGCCGCTCGAGCGGCGTACGCCGCACACGATCGTCGCCGCCGGGCTGCTCCAGCGCCAGCTCGCGACCGT
CCTGGAGGCCGGCGTCGCCTTCGAGCAGGAGGAGTCGACGATCGGCCTGCTCTGCGTGGCCGCGCCGGTGCTCGACGACA
CCGACCACGCGCTGGCGGCGATCAGCGTGGCCGGGCCGGTCGGACGGTTCCGGCCGCAGGCGCACGTCGACGCGGTCCGG
GCCGCGGCCACGGGCCTCGGCAGTGTGGTCGCGCGGAGGCGCTCGCTGCGCTGA

Upstream 100 bases:

>100_bases
CGCTGTTGGTTGCGAGGGTGGTGTCGGCCATGAGAAGAGCATCGAGGGGGGCGGGCGCCGACCGTGAGCCCGGCGTTCCA
CTCAGCGGTACGATCTTGGG

Downstream 100 bases:

>100_bases
GATCCGGCGCGTCCGCGGGCGCTCCGAGGACGCGGCCGAGGCTCAGTAGCCGTCGGCGACCACGACGGAGTCGTAGTCGA
GCGGCATCCGCGGGACCGTC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDLPGDESADLDTVLGKAVTMLRAFTVDDQVLSLAELVRRTGLAKATVHRVAGDLVDNRLLDRTALGYRLSGGLFELGMR
ASLERGLLELAMPFLQDLYERTHETVHLGLREGHDVVYVAKIGGHRQAAAPSRTGGRMPVHCTAIGKALLAHADAAVQRE
VLSGPLERRTPHTIVAAGLLQRQLATVLEAGVAFEQEESTIGLLCVAAPVLDDTDHALAAISVAGPVGRFRPQAHVDAVR
AAATGLGSVVARRRSLR

Sequences:

>Translated_257_residues
MDLPGDESADLDTVLGKAVTMLRAFTVDDQVLSLAELVRRTGLAKATVHRVAGDLVDNRLLDRTALGYRLSGGLFELGMR
ASLERGLLELAMPFLQDLYERTHETVHLGLREGHDVVYVAKIGGHRQAAAPSRTGGRMPVHCTAIGKALLAHADAAVQRE
VLSGPLERRTPHTIVAAGLLQRQLATVLEAGVAFEQEESTIGLLCVAAPVLDDTDHALAAISVAGPVGRFRPQAHVDAVR
AAATGLGSVVARRRSLR
>Mature_257_residues
MDLPGDESADLDTVLGKAVTMLRAFTVDDQVLSLAELVRRTGLAKATVHRVAGDLVDNRLLDRTALGYRLSGGLFELGMR
ASLERGLLELAMPFLQDLYERTHETVHLGLREGHDVVYVAKIGGHRQAAAPSRTGGRMPVHCTAIGKALLAHADAAVQRE
VLSGPLERRTPHTIVAAGLLQRQLATVLEAGVAFEQEESTIGLLCVAAPVLDDTDHALAAISVAGPVGRFRPQAHVDAVR
AAATGLGSVVARRRSLR

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=250, Percent_Identity=32.8, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786468, Length=222, Percent_Identity=32.8828828828829, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786715, Length=193, Percent_Identity=31.0880829015544, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87082359, Length=225, Percent_Identity=27.1111111111111, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788581, Length=195, Percent_Identity=31.2820512820513, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790752, Length=204, Percent_Identity=30.8823529411765, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789999, Length=212, Percent_Identity=29.7169811320755, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27375; Mature: 27375

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLPGDESADLDTVLGKAVTMLRAFTVDDQVLSLAELVRRTGLAKATVHRVAGDLVDNRL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LDRTALGYRLSGGLFELGMRASLERGLLELAMPFLQDLYERTHETVHLGLREGHDVVYVA
HHHHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCCEEEEE
KIGGHRQAAAPSRTGGRMPVHCTAIGKALLAHADAAVQREVLSGPLERRTPHTIVAAGLL
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHH
QRQLATVLEAGVAFEQEESTIGLLCVAAPVLDDTDHALAAISVAGPVGRFRPQAHVDAVR
HHHHHHHHHHHCCCCCCCCCCEEHEEEHHCCCCCCHHHHHHHHHCCHHHCCCHHHHHHHH
AAATGLGSVVARRRSLR
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLPGDESADLDTVLGKAVTMLRAFTVDDQVLSLAELVRRTGLAKATVHRVAGDLVDNRL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LDRTALGYRLSGGLFELGMRASLERGLLELAMPFLQDLYERTHETVHLGLREGHDVVYVA
HHHHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCCEEEEE
KIGGHRQAAAPSRTGGRMPVHCTAIGKALLAHADAAVQREVLSGPLERRTPHTIVAAGLL
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHH
QRQLATVLEAGVAFEQEESTIGLLCVAAPVLDDTDHALAAISVAGPVGRFRPQAHVDAVR
HHHHHHHHHHHCCCCCCCCCCEEHEEEHHCCCCCCHHHHHHHHHCCHHHCCCHHHHHHHH
AAATGLGSVVARRRSLR
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]