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The map label for this gene is atzB [H]

Identifier: 119715861

GI number: 119715861

Start: 1724724

End: 1726055

Strand: Direct

Name: atzB [H]

Synonym: Noca_1626

Alternate gene names: 119715861

Gene position: 1724724-1726055 (Clockwise)

Preceding gene: 119715860

Following gene: 119715862

Centisome position: 34.59

GC content: 74.02

Gene sequence:

>1332_bases
GTGACACTCGACGCCGACGACCGCGAGATCGCCGGGGGCTGGATCGCCCTCGACCAGGGCTTGGTCGCGGCCATCGGGGG
GCCGGGCGACGCACCCCCGCCCGCGACCCGGGTGCTGCGCGCGGACGGCTGCCTGGTCACCCCCGGGCTGATCAACACCC
ACCACCACATCTACCAGAACCTGACCCGCGCCCACCGGCCCTCGGTCAACACCTCGCTGTTCACCTGGCTCACCACGCTC
TACCCCCTCTGGGCGGGTCTCGACGAGGAGGCGGCGTACCTCTCGGCCTGGGTCGGTCTGGCCGAGCTCGCGCTCGGCGG
CTGCACGACCACCACCGACCACCTCTACGTCCACCCGCGCCACGGCGGTGACCTGATCTCCGCCGAGATCACCGCGGCGA
CCGAGCTCGGCATGCGGTTCCACCCGACCCGCGGCTCGATGAGCCTGTCCGAGAAGGACGGCGGCCTGCCGCCGGACTCC
GTCGTGCAGGACGACGACGAGATCCTCGCGGACAGCGAGCGGCTGGTCGCCCGCCACCACGACCCGTCCTGGGGCGCGAT
GGTGCGGATCGCACTGGCGCCCTGCTCGCCGTTCTCGGTCTCCTCCGACCTGATGCGGCGTACGGCGGAGCTGGCCGAGC
GGCTCGACGTCCGGCTGCACACCCACCTCGCCGAAGACCCCGACGAGGACCTCTTCGCCGCGAAGGCCTTCGGTCGCCGC
ACCATCGACCACTTCGAGGACGTCGGCTGGATGTCCGACCGCAGCTGGGTGGCGCACTGCATCTACCCCAACGACGACGA
GGTACGGCGGCTCGGCGCCGCCGGTGTCGGCGTCGCCCACTGTCCCTCGTCGAACATGCTGATCGGCGGGGGTGGGCTGG
CGCCGGTCGTGGAGCTGCGCGCGGCCGGGGCCCCGGTCGGGATCGGCTGCGACGGCTCCGCGTCCACCGACCACGCGTCA
CTGTGGCTGGAGGCCCGGACCGCCCTCCTGCTGGGGCACCAGCGCAAGGGGCCGACCGGCATGACCGCCCGCGACGTGCT
CGACATCGCGACCCGCGGGTCGGCCGCGTGCCTGGGCCGGACGGGTGAGCTCGGGACGTTGAGCGTCGGTGCGGTCGGCG
ACGTCGTCTGCTGGCCGCTGACCGGGATCGCGTTCGCCGGGGCACTCACCGACCCGGTCGAGGCGTGGCTGCGGTGCGGC
CCGGTCGCGGCCCGGCACACGATCGTCGCCGGCCGGGCCGTCGTGGTGGACGCCGCCCTCGTCCACCCCGGTCTCGAGGA
GATCCTGCACCGCCACCGTGCCGCCGCCCGCCGCCTCCAGCGGCTGGCCTGA

Upstream 100 bases:

>100_bases
CTCACGCGCGGGCCGTGCGATTCCGCCGACACGGCCGTGCGGGGATGGCTAGCGTCGCGGTGTGACCGTCGACTTGTTGA
TCGACGGGGCCGAGCATGTC

Downstream 100 bases:

>100_bases
CCACAGCCCGCCACAGCCTGACCAGAGATCGGAGCCCGCCATGTCGTCCCTAGGAGTCGAAGGCCACGTCGTCGACGCAG
GCAGCCGGGACCGCGCGGTC

Product: amidohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MTLDADDREIAGGWIALDQGLVAAIGGPGDAPPPATRVLRADGCLVTPGLINTHHHIYQNLTRAHRPSVNTSLFTWLTTL
YPLWAGLDEEAAYLSAWVGLAELALGGCTTTTDHLYVHPRHGGDLISAEITAATELGMRFHPTRGSMSLSEKDGGLPPDS
VVQDDDEILADSERLVARHHDPSWGAMVRIALAPCSPFSVSSDLMRRTAELAERLDVRLHTHLAEDPDEDLFAAKAFGRR
TIDHFEDVGWMSDRSWVAHCIYPNDDEVRRLGAAGVGVAHCPSSNMLIGGGGLAPVVELRAAGAPVGIGCDGSASTDHAS
LWLEARTALLLGHQRKGPTGMTARDVLDIATRGSAACLGRTGELGTLSVGAVGDVVCWPLTGIAFAGALTDPVEAWLRCG
PVAARHTIVAGRAVVVDAALVHPGLEEILHRHRAAARRLQRLA

Sequences:

>Translated_443_residues
MTLDADDREIAGGWIALDQGLVAAIGGPGDAPPPATRVLRADGCLVTPGLINTHHHIYQNLTRAHRPSVNTSLFTWLTTL
YPLWAGLDEEAAYLSAWVGLAELALGGCTTTTDHLYVHPRHGGDLISAEITAATELGMRFHPTRGSMSLSEKDGGLPPDS
VVQDDDEILADSERLVARHHDPSWGAMVRIALAPCSPFSVSSDLMRRTAELAERLDVRLHTHLAEDPDEDLFAAKAFGRR
TIDHFEDVGWMSDRSWVAHCIYPNDDEVRRLGAAGVGVAHCPSSNMLIGGGGLAPVVELRAAGAPVGIGCDGSASTDHAS
LWLEARTALLLGHQRKGPTGMTARDVLDIATRGSAACLGRTGELGTLSVGAVGDVVCWPLTGIAFAGALTDPVEAWLRCG
PVAARHTIVAGRAVVVDAALVHPGLEEILHRHRAAARRLQRLA
>Mature_442_residues
TLDADDREIAGGWIALDQGLVAAIGGPGDAPPPATRVLRADGCLVTPGLINTHHHIYQNLTRAHRPSVNTSLFTWLTTLY
PLWAGLDEEAAYLSAWVGLAELALGGCTTTTDHLYVHPRHGGDLISAEITAATELGMRFHPTRGSMSLSEKDGGLPPDSV
VQDDDEILADSERLVARHHDPSWGAMVRIALAPCSPFSVSSDLMRRTAELAERLDVRLHTHLAEDPDEDLFAAKAFGRRT
IDHFEDVGWMSDRSWVAHCIYPNDDEVRRLGAAGVGVAHCPSSNMLIGGGGLAPVVELRAAGAPVGIGCDGSASTDHASL
WLEARTALLLGHQRKGPTGMTARDVLDIATRGSAACLGRTGELGTLSVGAVGDVVCWPLTGIAFAGALTDPVEAWLRCGP
VAARHTIVAGRAVVVDAALVHPGLEEILHRHRAAARRLQRLA

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=342, Percent_Identity=22.8070175438596, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789249, Length=426, Percent_Identity=25.3521126760563, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082177, Length=334, Percent_Identity=23.0538922155689, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319963, Length=346, Percent_Identity=24.8554913294798, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24643849, Length=324, Percent_Identity=25.3086419753086, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 47022; Mature: 46891

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDADDREIAGGWIALDQGLVAAIGGPGDAPPPATRVLRADGCLVTPGLINTHHHIYQN
CCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCHHHEEECCCCEECCCHHHHHHHHHHH
LTRAHRPSVNTSLFTWLTTLYPLWAGLDEEAAYLSAWVGLAELALGGCTTTTDHLYVHPR
HHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
HGGDLISAEITAATELGMRFHPTRGSMSLSEKDGGLPPDSVVQDDDEILADSERLVARHH
CCCCEEEEEHHHHHHCCCEECCCCCCCEECCCCCCCCCCHHCCCCHHHHHCCHHHHHHCC
DPSWGAMVRIALAPCSPFSVSSDLMRRTAELAERLDVRLHTHLAEDPDEDLFAAKAFGRR
CCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TIDHFEDVGWMSDRSWVAHCIYPNDDEVRRLGAAGVGVAHCPSSNMLIGGGGLAPVVELR
HHHHHHHCCCCCCCCEEEEEECCCHHHHHHHCCCCCCEEECCCCCEEEECCCCCHHHHHH
AAGAPVGIGCDGSASTDHASLWLEARTALLLGHQRKGPTGMTARDVLDIATRGSAACLGR
HCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEECC
TGELGTLSVGAVGDVVCWPLTGIAFAGALTDPVEAWLRCGPVAARHTIVAGRAVVVDAAL
CCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHEEEECCHHEEHHHH
VHPGLEEILHRHRAAARRLQRLA
HCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLDADDREIAGGWIALDQGLVAAIGGPGDAPPPATRVLRADGCLVTPGLINTHHHIYQN
CCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCHHHEEECCCCEECCCHHHHHHHHHHH
LTRAHRPSVNTSLFTWLTTLYPLWAGLDEEAAYLSAWVGLAELALGGCTTTTDHLYVHPR
HHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
HGGDLISAEITAATELGMRFHPTRGSMSLSEKDGGLPPDSVVQDDDEILADSERLVARHH
CCCCEEEEEHHHHHHCCCEECCCCCCCEECCCCCCCCCCHHCCCCHHHHHCCHHHHHHCC
DPSWGAMVRIALAPCSPFSVSSDLMRRTAELAERLDVRLHTHLAEDPDEDLFAAKAFGRR
CCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TIDHFEDVGWMSDRSWVAHCIYPNDDEVRRLGAAGVGVAHCPSSNMLIGGGGLAPVVELR
HHHHHHHCCCCCCCCEEEEEECCCHHHHHHHCCCCCCEEECCCCCEEEECCCCCHHHHHH
AAGAPVGIGCDGSASTDHASLWLEARTALLLGHQRKGPTGMTARDVLDIATRGSAACLGR
HCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEECC
TGELGTLSVGAVGDVVCWPLTGIAFAGALTDPVEAWLRCGPVAARHTIVAGRAVVVDAAL
CCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHEEEECCHHEEHHHH
VHPGLEEILHRHRAAARRLQRLA
HCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]