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The map label for this gene is 119715729

Identifier: 119715729

GI number: 119715729

Start: 1581001

End: 1582407

Strand: Direct

Name: 119715729

Synonym: Noca_1493

Alternate gene names: NA

Gene position: 1581001-1582407 (Clockwise)

Preceding gene: 119715728

Following gene: 119715730

Centisome position: 31.71

GC content: 74.56

Gene sequence:

>1407_bases
ATGAGCGGGGTCACGGTCGAGTCGACCGCGCGCGAGCAGGCGGCCGCCGTACGCGCGAAGGAGATCTCGGCGCGCGAGCT
GCTCGACCTGCACCTGGCGCGGATCGCCGAGCGCAACCCGGAGCTGAACGCGATCGTCTCTCTCGACGAGGAGCGTGCCC
GCGAGGGCGCCGCCGAGGCCGACCGGGCGCTCGCCGCCGCCGATCGTGACGGCACCGACGTCGGCCCGCTGCACGGGCTG
CCGTTCGCGTTCAAGGACACCCACGCGGTCGCCGGCTGGCGCACCACCTACGGATCGCCGCTGTACGCCGACCACGTCCC
CGACGCCGACGAGCTGATCGTCGAGCGGGTACGCCGCGCCGGTGTCGTGGTGATCGGCAAGACCAACGTGCCGGAGTTCG
CGGCCGGGTCGCACACGTTCAACCGGGTCTTCGGGACCACCCTCAACCCGGTCGACCCGTCGCGCTCGGCCGGCGGCTCC
AGCGGGGGAGCGGCCAGCGCGCTGGCCGCCGGGATGGTGCCCCTCGCGGACGGCTCGGACATGGGCGGCTCGTTGCGCAA
CCCCGCGTCGTTCTGCGGCGTCTTCGGGCTGCGCCCCTCGCTCGGCCGGGTGCCGGAGTGGCCGCTGTACAACCAGTGGG
AGACGACCTCGGTGGGTGGCCCGATGGCGCGCAACGTCGGCGACCTCGCGCTGCTCCTCTCGGTGCTGGCCGGGCCCGAC
CCGCGCGCACCCCAGGCGCTCGGGGACCCGGGCGCGACCTTCGCCCCTCCACTCGCGGGCTCGCTGGCCGGGCTGCGGGT
GGCGGTCTCGGTCGACCTCGGCGGTGCGTTCGAGGTCGACCACGAGGTGGCGGCGGTCGTGGAGTCCTCGGCGGCGGCCT
TCACGGCCGCGGGTGCCCAGGTGACGGCGGCGCACCCGGTCCTCACCGAGGCCGACGACACGTTCCGGACGCTGCGCGCC
TGGCACCTGCAGGCCAAGCTCGGCGGCCTGCTCGCCGCCCACCCCGACGGTCTCAAGCCGTCGCTGGCCGACAACATCCG
GCTCGGCGAACACCTCACCGGCGCCGACGTGGCCCGCGCCTATACCCAGCGCACCGCGCTGTCCGAGCGGATGCGGGAGT
TCTTCGTCCCCGGCGGGCAGGGCTTCGACCTGCTGGTGCTCCCGGTCTCCCAGGTGCCGCCGTTCCCGGCGGACCAGGAG
TACCCCGCCACCATCAACGGCCGGCCGATGCAGACCTACCTGGACTGGATGCGCGCGGCGTACCTGATCACCGTCACCGG
CTGCCCCGCGATCTCGGTGCCGTTCGGGCACACCTCCGACGGGTTGCCCATCGGCCTGCAGCTGGTCGCCGCGCACGGCC
GGGACCGGTTCCTCCTCGAGACCGCCGCGGCGCTCGAGGCCCGCTGA

Upstream 100 bases:

>100_bases
GAAGTTGGAACTTCTGGCCCGAAGTTTCGGCCCAACACTTCCGGTTTCCCCGGTTCACCGGGGAAACCGCCGGGGGCTCG
CGGCGGGGCGGGGCGCGGCG

Downstream 100 bases:

>100_bases
GCTGTTCGGCACTGCTGCCGGGCTGCTGCCGGGCGGCCGTCGATCCGGTCTGGTCCACGCCGTCTCGCTGTCCACAGGCA
CGGGAGGAACCTGTGGGTTT

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSGVTVESTAREQAAAVRAKEISARELLDLHLARIAERNPELNAIVSLDEERAREGAAEADRALAAADRDGTDVGPLHGL
PFAFKDTHAVAGWRTTYGSPLYADHVPDADELIVERVRRAGVVVIGKTNVPEFAAGSHTFNRVFGTTLNPVDPSRSAGGS
SGGAASALAAGMVPLADGSDMGGSLRNPASFCGVFGLRPSLGRVPEWPLYNQWETTSVGGPMARNVGDLALLLSVLAGPD
PRAPQALGDPGATFAPPLAGSLAGLRVAVSVDLGGAFEVDHEVAAVVESSAAAFTAAGAQVTAAHPVLTEADDTFRTLRA
WHLQAKLGGLLAAHPDGLKPSLADNIRLGEHLTGADVARAYTQRTALSERMREFFVPGGQGFDLLVLPVSQVPPFPADQE
YPATINGRPMQTYLDWMRAAYLITVTGCPAISVPFGHTSDGLPIGLQLVAAHGRDRFLLETAAALEAR

Sequences:

>Translated_468_residues
MSGVTVESTAREQAAAVRAKEISARELLDLHLARIAERNPELNAIVSLDEERAREGAAEADRALAAADRDGTDVGPLHGL
PFAFKDTHAVAGWRTTYGSPLYADHVPDADELIVERVRRAGVVVIGKTNVPEFAAGSHTFNRVFGTTLNPVDPSRSAGGS
SGGAASALAAGMVPLADGSDMGGSLRNPASFCGVFGLRPSLGRVPEWPLYNQWETTSVGGPMARNVGDLALLLSVLAGPD
PRAPQALGDPGATFAPPLAGSLAGLRVAVSVDLGGAFEVDHEVAAVVESSAAAFTAAGAQVTAAHPVLTEADDTFRTLRA
WHLQAKLGGLLAAHPDGLKPSLADNIRLGEHLTGADVARAYTQRTALSERMREFFVPGGQGFDLLVLPVSQVPPFPADQE
YPATINGRPMQTYLDWMRAAYLITVTGCPAISVPFGHTSDGLPIGLQLVAAHGRDRFLLETAAALEAR
>Mature_467_residues
SGVTVESTAREQAAAVRAKEISARELLDLHLARIAERNPELNAIVSLDEERAREGAAEADRALAAADRDGTDVGPLHGLP
FAFKDTHAVAGWRTTYGSPLYADHVPDADELIVERVRRAGVVVIGKTNVPEFAAGSHTFNRVFGTTLNPVDPSRSAGGSS
GGAASALAAGMVPLADGSDMGGSLRNPASFCGVFGLRPSLGRVPEWPLYNQWETTSVGGPMARNVGDLALLLSVLAGPDP
RAPQALGDPGATFAPPLAGSLAGLRVAVSVDLGGAFEVDHEVAAVVESSAAAFTAAGAQVTAAHPVLTEADDTFRTLRAW
HLQAKLGGLLAAHPDGLKPSLADNIRLGEHLTGADVARAYTQRTALSERMREFFVPGGQGFDLLVLPVSQVPPFPADQEY
PATINGRPMQTYLDWMRAAYLITVTGCPAISVPFGHTSDGLPIGLQLVAAHGRDRFLLETAAALEAR

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=507, Percent_Identity=28.0078895463511, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI195972892, Length=498, Percent_Identity=27.1084337349398, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI166795287, Length=214, Percent_Identity=31.7757009345794, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537465, Length=501, Percent_Identity=27.7445109780439, Blast_Score=138, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17543272, Length=426, Percent_Identity=28.169014084507, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17538252, Length=241, Percent_Identity=31.9502074688797, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17556264, Length=257, Percent_Identity=31.5175097276265, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71990152, Length=172, Percent_Identity=37.2093023255814, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17556276, Length=190, Percent_Identity=32.6315789473684, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17556278, Length=190, Percent_Identity=32.6315789473684, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538254, Length=224, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319685, Length=399, Percent_Identity=26.8170426065163, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320448, Length=237, Percent_Identity=32.9113924050633, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323950, Length=434, Percent_Identity=23.2718894009217, Blast_Score=83, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24644968, Length=493, Percent_Identity=27.1805273833671, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI21356731, Length=483, Percent_Identity=28.7784679089027, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24648435, Length=497, Percent_Identity=26.9617706237425, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24648437, Length=497, Percent_Identity=26.9617706237425, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI45550774, Length=497, Percent_Identity=26.9617706237425, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24648113, Length=469, Percent_Identity=28.5714285714286, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24652985, Length=238, Percent_Identity=33.6134453781513, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19922090, Length=238, Percent_Identity=33.6134453781513, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24652981, Length=238, Percent_Identity=33.6134453781513, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24652983, Length=238, Percent_Identity=33.6134453781513, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24648441, Length=424, Percent_Identity=26.6509433962264, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24648439, Length=424, Percent_Identity=26.6509433962264, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI161078093, Length=285, Percent_Identity=29.8245614035088, Blast_Score=99, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 48928; Mature: 48796

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGVTVESTAREQAAAVRAKEISARELLDLHLARIAERNPELNAIVSLDEERAREGAAEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCHHHH
DRALAAADRDGTDVGPLHGLPFAFKDTHAVAGWRTTYGSPLYADHVPDADELIVERVRRA
HHHHHHCCCCCCCCCCCCCCCCEECCCCEECCCHHCCCCCEECCCCCCHHHHHHHHHHHC
GVVVIGKTNVPEFAAGSHTFNRVFGTTLNPVDPSRSAGGSSGGAASALAAGMVPLADGSD
CEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCEECCCCCC
MGGSLRNPASFCGVFGLRPSLGRVPEWPLYNQWETTSVGGPMARNVGDLALLLSVLAGPD
CCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
PRAPQALGDPGATFAPPLAGSLAGLRVAVSVDLGGAFEVDHEVAAVVESSAAAFTAAGAQ
CCCCCCCCCCCCCCCCCHHCCCCCEEEEEEEECCCCEECCHHHHHHHHHHHHHEEECCCE
VTAAHPVLTEADDTFRTLRAWHLQAKLGGLLAAHPDGLKPSLADNIRLGEHLTGADVARA
EEECCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHCCCCCCCCCCHHHHHHH
YTQRTALSERMREFFVPGGQGFDLLVLPVSQVPPFPADQEYPATINGRPMQTYLDWMRAA
HHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHE
YLITVTGCPAISVPFGHTSDGLPIGLQLVAAHGRDRFLLETAAALEAR
EEEEEECCCEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SGVTVESTAREQAAAVRAKEISARELLDLHLARIAERNPELNAIVSLDEERAREGAAEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCHHHH
DRALAAADRDGTDVGPLHGLPFAFKDTHAVAGWRTTYGSPLYADHVPDADELIVERVRRA
HHHHHHCCCCCCCCCCCCCCCCEECCCCEECCCHHCCCCCEECCCCCCHHHHHHHHHHHC
GVVVIGKTNVPEFAAGSHTFNRVFGTTLNPVDPSRSAGGSSGGAASALAAGMVPLADGSD
CEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCEECCCCCC
MGGSLRNPASFCGVFGLRPSLGRVPEWPLYNQWETTSVGGPMARNVGDLALLLSVLAGPD
CCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
PRAPQALGDPGATFAPPLAGSLAGLRVAVSVDLGGAFEVDHEVAAVVESSAAAFTAAGAQ
CCCCCCCCCCCCCCCCCHHCCCCCEEEEEEEECCCCEECCHHHHHHHHHHHHHEEECCCE
VTAAHPVLTEADDTFRTLRAWHLQAKLGGLLAAHPDGLKPSLADNIRLGEHLTGADVARA
EEECCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHCCCCCCCCCCHHHHHHH
YTQRTALSERMREFFVPGGQGFDLLVLPVSQVPPFPADQEYPATINGRPMQTYLDWMRAA
HHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHE
YLITVTGCPAISVPFGHTSDGLPIGLQLVAAHGRDRFLLETAAALEAR
EEEEEECCCEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]