Click here to switch to the map view.

The map label for this gene is degU [H]

Identifier: 119715674

GI number: 119715674

Start: 1524224

End: 1524865

Strand: Direct

Name: degU [H]

Synonym: Noca_1438

Alternate gene names: 119715674

Gene position: 1524224-1524865 (Clockwise)

Preceding gene: 119715673

Following gene: 119715675

Centisome position: 30.57

GC content: 66.04

Gene sequence:

>642_bases
GTGCTCGTGGTCGATGACCAGGAGCTGTTCCGTCGAGGCCTGACGATGCTGCTCGGAACCGAGGCCGGTATCGAGGTGGT
CGGCGAAGCCGGCGACGGCGTCGAGGGCACCAACCTCGCGGCGACTGCCGCACCCGACGTCGTGCTCCTCGACATCCGGA
TGCCGAAGCGCTCCGGGATCGAGGCGTGCCTCGCGATCAAGGAGGCCGTCCCGTCGGCGAAGATCATCATGCTGACGGTC
TCCGACGAGGAGGCTGACCTCTACGAGGCGGTCAAGAGCGGCGCCTCCGGCTACCTGCTCAAGGACTCCTCGATCGAGGA
GGTCGCGCAGGCGGTCCGCGTCGTCGCGGACGGCCAGTCGCTGATCAGCCCGTCGATGGCGGTCAAGCTGATCGACGAGT
TCAAGCAGATGTCGCGCCCCGAGCGCGACCACGTCCCCGGCCTACGGCTCACCGAGCGAGAGCTCGAGGTGCTGCGCCTG
GTGGCGAAGGGCATGAACAACCGGGAGATCGCCAAGGAGCTGTTCATCAGCGAGAACACGGTCAAGAACCACGTGCGCAA
CATCTTGGAGAAGCTCCAGCTGCACTCGCGCATGGAGGCCGTGATGTACGCCGTCAAGGAGAAGCTGCTCGAGCTGCCGT
GA

Upstream 100 bases:

>100_bases
GTCGCGTCACCACCCGCATATGCGACCTTGGGGGGCCTGATCGTGCCATGATGCGGGGGTGGGAGACGAGACGACCGACG
CCGGACGGGAACCGATCCGG

Downstream 100 bases:

>100_bases
CGCCCGGCACGCACTCTGGCGGCGTTGTCGTCGCTCGACGGCCCGCTTCGCTCAAAGGCCGCCTTCGCTCCTCCGCCTTG
CCAGAGCACGCACCGGACGC

Product: response regulator receiver

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MLVVDDQELFRRGLTMLLGTEAGIEVVGEAGDGVEGTNLAATAAPDVVLLDIRMPKRSGIEACLAIKEAVPSAKIIMLTV
SDEEADLYEAVKSGASGYLLKDSSIEEVAQAVRVVADGQSLISPSMAVKLIDEFKQMSRPERDHVPGLRLTERELEVLRL
VAKGMNNREIAKELFISENTVKNHVRNILEKLQLHSRMEAVMYAVKEKLLELP

Sequences:

>Translated_213_residues
MLVVDDQELFRRGLTMLLGTEAGIEVVGEAGDGVEGTNLAATAAPDVVLLDIRMPKRSGIEACLAIKEAVPSAKIIMLTV
SDEEADLYEAVKSGASGYLLKDSSIEEVAQAVRVVADGQSLISPSMAVKLIDEFKQMSRPERDHVPGLRLTERELEVLRL
VAKGMNNREIAKELFISENTVKNHVRNILEKLQLHSRMEAVMYAVKEKLLELP
>Mature_213_residues
MLVVDDQELFRRGLTMLLGTEAGIEVVGEAGDGVEGTNLAATAAPDVVLLDIRMPKRSGIEACLAIKEAVPSAKIIMLTV
SDEEADLYEAVKSGASGYLLKDSSIEEVAQAVRVVADGQSLISPSMAVKLIDEFKQMSRPERDHVPGLRLTERELEVLRL
VAKGMNNREIAKELFISENTVKNHVRNILEKLQLHSRMEAVMYAVKEKLLELP

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=208, Percent_Identity=41.8269230769231, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=36.3636363636364, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787473, Length=211, Percent_Identity=36.9668246445498, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1790102, Length=197, Percent_Identity=34.010152284264, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1786747, Length=212, Percent_Identity=27.8301886792453, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1788712, Length=208, Percent_Identity=23.0769230769231, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87082052, Length=101, Percent_Identity=38.6138613861386, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23379; Mature: 23379

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVVDDQELFRRGLTMLLGTEAGIEVVGEAGDGVEGTNLAATAAPDVVLLDIRMPKRSGI
CEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCEEEEEEECCCHHHH
EACLAIKEAVPSAKIIMLTVSDEEADLYEAVKSGASGYLLKDSSIEEVAQAVRVVADGQS
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCHH
LISPSMAVKLIDEFKQMSRPERDHVPGLRLTERELEVLRLVAKGMNNREIAKELFISENT
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCHHH
VKNHVRNILEKLQLHSRMEAVMYAVKEKLLELP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLVVDDQELFRRGLTMLLGTEAGIEVVGEAGDGVEGTNLAATAAPDVVLLDIRMPKRSGI
CEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCEEEEEEECCCHHHH
EACLAIKEAVPSAKIIMLTVSDEEADLYEAVKSGASGYLLKDSSIEEVAQAVRVVADGQS
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCHH
LISPSMAVKLIDEFKQMSRPERDHVPGLRLTERELEVLRLVAKGMNNREIAKELFISENT
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCHHH
VKNHVRNILEKLQLHSRMEAVMYAVKEKLLELP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]