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The map label for this gene is cofE [H]

Identifier: 119715645

GI number: 119715645

Start: 1490556

End: 1491521

Strand: Reverse

Name: cofE [H]

Synonym: Noca_1409

Alternate gene names: 119715645

Gene position: 1491521-1490556 (Counterclockwise)

Preceding gene: 119715646

Following gene: 119715644

Centisome position: 29.91

GC content: 75.98

Gene sequence:

>966_bases
ATGACGCACCTCGAGGTCACCGCCCCCGACGGCGCGCCGGAGATCCACCCCGGCGACGACCTGGTCGAGCTGCTCGTGGC
GCTGACCGAGCTCGCCGACGGCGACATCGTGGCCGTGACGAGCAAGGTGGTCAGCAAGGCCGAGGGCCGGGTGCGGGCCG
GCACCAGGGAGCAGGCGCTCGCCGGCGAGACGGCCCGGGTGGTGGCCCGCCGTGGCGGGACCACGATCGTGCGCACCCAC
CTGGGCCTGACCATGGCGGCGGCCGGCATCGACAGCTCCAACGTGCCGGCCGGCCAGGTGCTGCTGCTCCCTCTCGACCC
CGACGCATCCGCCCGTGGCCTGCGCGAGGGGATCCGGCAGCGCACCGGGCGCAACGTCGCGGTGGTCGTCACCGACACCG
CCGGACGCGCCTGGCGCGAGGGCCAGACCGACATCGCGATCGGCGCCGCCGGGCTGGTCGTGGCCGAGGAGTACGCCGGG
CGGACCGATGCGTGGGGAAACGAGCTCGCCGTCACCCTCCCTGCCGTCGCGGACGAGGTGGCGGGCATGGCCGAGCTCGC
GCAGGGCAAGCTCGGCGGTCGTCCGTTCGCGGTCGTGCGCGGACGCGGCGACCTGGTGCTGCCGCCCGGCGAGGACGGTC
CCGGCGCCGCAGCACTGGTCCGTGATGAGGGCGGCGACCTGTTCGGGTACGGCGCCCGCGAGGCCGTGATCCGGGCCCTG
AAGGGGGACGCCGCCGACCGGGCGCCGTTCGGCGCGCCCGTCGCGGCCGAGGAGCTGGCGGCGGTGATCGCCGACACCCT
CGGGCTGGTCGCCTCGCGCTCGATCGGCGCCGGGCCCGCCGAGCTGCTGCTCACCGTGCCGCGCGGACTGGTCCGCCCGG
TCGCAGCCCTGGCCTTCGCCCACGGCTGGGACGTGTTGCCCACCGATTCACCGAGCAAGACGCGGTTGCGGCCGACACCG
CACTGA

Upstream 100 bases:

>100_bases
TGCTCGCCGGTGGCCTGGCGTGCCGGGCCGTGCCGCTGATGATGACCGATCCGGATGCGACCGCTGCCATGGCGGCGGCC
GCCATCGAGCTGGTCCGCGG

Downstream 100 bases:

>100_bases
GGCACCCGTAGACTCTGCCGACGACCGACCCGACCACGCCCGCAACACCGAGGACGAACACCGTGGCCAAGCCCGCCAAG
AACGACCGCCAGGCGGTCAT

Product: F420-dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTHLEVTAPDGAPEIHPGDDLVELLVALTELADGDIVAVTSKVVSKAEGRVRAGTREQALAGETARVVARRGGTTIVRTH
LGLTMAAAGIDSSNVPAGQVLLLPLDPDASARGLREGIRQRTGRNVAVVVTDTAGRAWREGQTDIAIGAAGLVVAEEYAG
RTDAWGNELAVTLPAVADEVAGMAELAQGKLGGRPFAVVRGRGDLVLPPGEDGPGAAALVRDEGGDLFGYGAREAVIRAL
KGDAADRAPFGAPVAAEELAAVIADTLGLVASRSIGAGPAELLLTVPRGLVRPVAALAFAHGWDVLPTDSPSKTRLRPTP
H

Sequences:

>Translated_321_residues
MTHLEVTAPDGAPEIHPGDDLVELLVALTELADGDIVAVTSKVVSKAEGRVRAGTREQALAGETARVVARRGGTTIVRTH
LGLTMAAAGIDSSNVPAGQVLLLPLDPDASARGLREGIRQRTGRNVAVVVTDTAGRAWREGQTDIAIGAAGLVVAEEYAG
RTDAWGNELAVTLPAVADEVAGMAELAQGKLGGRPFAVVRGRGDLVLPPGEDGPGAAALVRDEGGDLFGYGAREAVIRAL
KGDAADRAPFGAPVAAEELAAVIADTLGLVASRSIGAGPAELLLTVPRGLVRPVAALAFAHGWDVLPTDSPSKTRLRPTP
H
>Mature_320_residues
THLEVTAPDGAPEIHPGDDLVELLVALTELADGDIVAVTSKVVSKAEGRVRAGTREQALAGETARVVARRGGTTIVRTHL
GLTMAAAGIDSSNVPAGQVLLLPLDPDASARGLREGIRQRTGRNVAVVVTDTAGRAWREGQTDIAIGAAGLVVAEEYAGR
TDAWGNELAVTLPAVADEVAGMAELAQGKLGGRPFAVVRGRGDLVLPPGEDGPGAAALVRDEGGDLFGYGAREAVIRALK
GDAADRAPFGAPVAAEELAAVIADTLGLVASRSIGAGPAELLLTVPRGLVRPVAALAFAHGWDVLPTDSPSKTRLRPTPH

Specific function: Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives [H]

COG id: COG1478

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the CofE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002847
- InterPro:   IPR008225
- InterPro:   IPR019943
- InterPro:   IPR000415 [H]

Pfam domain/function: PF01996 F420_ligase; PF00881 Nitroreductase [H]

EC number: NA

Molecular weight: Translated: 32802; Mature: 32670

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHLEVTAPDGAPEIHPGDDLVELLVALTELADGDIVAVTSKVVSKAEGRVRAGTREQAL
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCHHHHH
AGETARVVARRGGTTIVRTHLGLTMAAAGIDSSNVPAGQVLLLPLDPDASARGLREGIRQ
CCHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
RTGRNVAVVVTDTAGRAWREGQTDIAIGAAGLVVAEEYAGRTDAWGNELAVTLPAVADEV
HCCCEEEEEEECCCCCHHHCCCCCEEEECHHHEEEHHHCCCCCCCCCCEEEEEHHHHHHH
AGMAELAQGKLGGRPFAVVRGRGDLVLPPGEDGPGAAALVRDEGGDLFGYGAREAVIRAL
HHHHHHHHCCCCCCCEEEEECCCCEEECCCCCCCCCEEEEECCCCCEECCCHHHHHHHHH
KGDAADRAPFGAPVAAEELAAVIADTLGLVASRSIGAGPAELLLTVPRGLVRPVAALAFA
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHH
HGWDVLPTDSPSKTRLRPTPH
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
THLEVTAPDGAPEIHPGDDLVELLVALTELADGDIVAVTSKVVSKAEGRVRAGTREQAL
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCHHHHH
AGETARVVARRGGTTIVRTHLGLTMAAAGIDSSNVPAGQVLLLPLDPDASARGLREGIRQ
CCHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
RTGRNVAVVVTDTAGRAWREGQTDIAIGAAGLVVAEEYAGRTDAWGNELAVTLPAVADEV
HCCCEEEEEEECCCCCHHHCCCCCEEEECHHHEEEHHHCCCCCCCCCCEEEEEHHHHHHH
AGMAELAQGKLGGRPFAVVRGRGDLVLPPGEDGPGAAALVRDEGGDLFGYGAREAVIRAL
HHHHHHHHCCCCCCCEEEEECCCCEEECCCCCCCCCEEEEECCCCCEECCCHHHHHHHHH
KGDAADRAPFGAPVAAEELAAVIADTLGLVASRSIGAGPAELLLTVPRGLVRPVAALAFA
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHH
HGWDVLPTDSPSKTRLRPTPH
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]