BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is abcA [H]

Identifier: 119715640

GI number: 119715640

Start: 1483846

End: 1484646

Strand: Direct

Name: abcA [H]

Synonym: Noca_1404

Alternate gene names: 119715640

Gene position: 1483846-1484646 (Clockwise)

Preceding gene: 119715639

Following gene: 119715641

Centisome position: 29.76

GC content: 67.79

Gene sequence:

>801_bases
GTGACCTATTCCGCCAGCACCTCGATCGTCGTCGACCACGCGACCAAGGACTTCACGCTCCGCTACCACCGCACCTTCAA
GCAGATGACGGTCGCCGCGCTGCGCCGGCAGAGCATCGCGGACTCCTTCCGGGCCGTCGACGACGTCTCCTTCACGGTCC
AGCAGGGCGAGTCCATCGGCCTGATGGGCCTCAACGGGTCGGGCAAGAGCACGCTGCTCAAGCTGATCAACGGCGTGATG
CGCCCCGACAGCGGCCGGGTCCTGACCCGCGGGCGGATCTCGGGGCTGATCGCCACCGGCGCCGGCTTCCACCCCCAGCT
GACCGGACGCGAGAACGTCTACCTCAACGCGGCCGTGCTCGGCATGAGCGAGGCCGAGACGCGGCGCAAGTTCGACGACA
TCGCGGAGTTCGCCGACATCGGCAAGTTCCTCGACTCACCCGTCGGCCACTACTCCTCGGGCATGTTCGCGCGGCTCGGG
TTCGCCGTCGCCATCCACGTCGACTCCGACATCTTCCTCGCCGACGAGGTGCTGGCGGTGGGGGACAAGCCCTTCAAGCA
GAAGTGCCTGCAGCGGATGCAGGAGATCCGCGACGGGGGGCGGACGCTCTTCTACGTCAGCCACGCCGCCGGCTCGGTGC
GCAAGATGTGCGACCGGGTGATCGTGCTGGAGCAGGGGCGCCTCGCCTTCGACGGCGGCGTCGACGAGGGCATCAAGTTC
GTCAAGTACGACGAGGAGAAGGCGACCGACGAGGAGCTCGGCGTCGACGACACCGACGACGAGCTCGGCGCCGACATATA
G

Upstream 100 bases:

>100_bases
TGTTCGCCTACAGCGCGTTGGCCCTCGTCGTCAGTGTCGCTGTCCTGGCGCTCGGGCAGCTGATCTTCTCCCGGCTCGAG
AACAAGATCCCGGAGCGCCT

Downstream 100 bases:

>100_bases
CCATCCGCGGATATCCGCGCCACCGCATCAGGCGGCGGCCCGCAGCCGAGCGCCCACCGCAACCAGAGCGTGGGGCCATC
ACCCCGTGGCTGAGCTCGCG

Product: ABC transporter-like protein

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTYSASTSIVVDHATKDFTLRYHRTFKQMTVAALRRQSIADSFRAVDDVSFTVQQGESIGLMGLNGSGKSTLLKLINGVM
RPDSGRVLTRGRISGLIATGAGFHPQLTGRENVYLNAAVLGMSEAETRRKFDDIAEFADIGKFLDSPVGHYSSGMFARLG
FAVAIHVDSDIFLADEVLAVGDKPFKQKCLQRMQEIRDGGRTLFYVSHAAGSVRKMCDRVIVLEQGRLAFDGGVDEGIKF
VKYDEEKATDEELGVDDTDDELGADI

Sequences:

>Translated_266_residues
MTYSASTSIVVDHATKDFTLRYHRTFKQMTVAALRRQSIADSFRAVDDVSFTVQQGESIGLMGLNGSGKSTLLKLINGVM
RPDSGRVLTRGRISGLIATGAGFHPQLTGRENVYLNAAVLGMSEAETRRKFDDIAEFADIGKFLDSPVGHYSSGMFARLG
FAVAIHVDSDIFLADEVLAVGDKPFKQKCLQRMQEIRDGGRTLFYVSHAAGSVRKMCDRVIVLEQGRLAFDGGVDEGIKF
VKYDEEKATDEELGVDDTDDELGADI
>Mature_265_residues
TYSASTSIVVDHATKDFTLRYHRTFKQMTVAALRRQSIADSFRAVDDVSFTVQQGESIGLMGLNGSGKSTLLKLINGVMR
PDSGRVLTRGRISGLIATGAGFHPQLTGRENVYLNAAVLGMSEAETRRKFDDIAEFADIGKFLDSPVGHYSSGMFARLGF
AVAIHVDSDIFLADEVLAVGDKPFKQKCLQRMQEIRDGGRTLFYVSHAAGSVRKMCDRVIVLEQGRLAFDGGVDEGIKFV
KYDEEKATDEELGVDDTDDELGADI

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=198, Percent_Identity=29.7979797979798, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI6005701, Length=198, Percent_Identity=30.8080808080808, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI27477115, Length=223, Percent_Identity=29.1479820627803, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI153792144, Length=204, Percent_Identity=27.9411764705882, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI31657092, Length=199, Percent_Identity=30.1507537688442, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI27881501, Length=204, Percent_Identity=25.4901960784314, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI30795238, Length=204, Percent_Identity=25.4901960784314, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI150417984, Length=195, Percent_Identity=25.6410256410256, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI27262624, Length=204, Percent_Identity=27.9411764705882, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI27262626, Length=204, Percent_Identity=27.9411764705882, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI45446740, Length=203, Percent_Identity=28.0788177339901, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI47078218, Length=203, Percent_Identity=28.0788177339901, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI105990541, Length=199, Percent_Identity=26.1306532663317, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI116734710, Length=196, Percent_Identity=27.5510204081633, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI21536376, Length=198, Percent_Identity=26.2626262626263, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789032, Length=208, Percent_Identity=26.4423076923077, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081782, Length=215, Percent_Identity=26.9767441860465, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787029, Length=215, Percent_Identity=27.906976744186, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786398, Length=211, Percent_Identity=26.5402843601896, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081709, Length=194, Percent_Identity=24.7422680412371, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI48994943, Length=230, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI48995001, Length=215, Percent_Identity=28.8372093023256, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787089, Length=210, Percent_Identity=24.7619047619048, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789672, Length=222, Percent_Identity=26.5765765765766, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788897, Length=206, Percent_Identity=26.2135922330097, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790467, Length=213, Percent_Identity=23.4741784037559, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787370, Length=203, Percent_Identity=24.6305418719212, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789593, Length=224, Percent_Identity=29.4642857142857, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081791, Length=207, Percent_Identity=23.6714975845411, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788210, Length=219, Percent_Identity=26.027397260274, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788761, Length=209, Percent_Identity=24.8803827751196, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786703, Length=197, Percent_Identity=32.48730964467, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787792, Length=201, Percent_Identity=26.865671641791, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786253, Length=198, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788450, Length=204, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787758, Length=195, Percent_Identity=24.6153846153846, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786872, Length=208, Percent_Identity=27.4038461538462, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790525, Length=232, Percent_Identity=25.8620689655172, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786981, Length=189, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790190, Length=221, Percent_Identity=25.3393665158371, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787712, Length=196, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082267, Length=223, Percent_Identity=23.7668161434978, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788225, Length=208, Percent_Identity=25, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788540, Length=203, Percent_Identity=29.5566502463054, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789873, Length=209, Percent_Identity=28.7081339712919, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=201, Percent_Identity=25.3731343283582, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115533608, Length=237, Percent_Identity=24.8945147679325, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71983523, Length=203, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=203, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=203, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643674, Length=197, Percent_Identity=28.4263959390863, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221500365, Length=200, Percent_Identity=26, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI116007184, Length=200, Percent_Identity=26, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24666092, Length=201, Percent_Identity=26.3681592039801, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221512771, Length=199, Percent_Identity=25.1256281407035, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574150, Length=202, Percent_Identity=27.2277227722772, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007328, Length=202, Percent_Identity=27.2277227722772, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 29114; Mature: 28983

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYSASTSIVVDHATKDFTLRYHRTFKQMTVAALRRQSIADSFRAVDDVSFTVQQGESIG
CCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEE
LMGLNGSGKSTLLKLINGVMRPDSGRVLTRGRISGLIATGAGFHPQLTGRENVYLNAAVL
EEEECCCCHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEE
GMSEAETRRKFDDIAEFADIGKFLDSPVGHYSSGMFARLGFAVAIHVDSDIFLADEVLAV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEEEEEECCCEEEHHHHHHC
GDKPFKQKCLQRMQEIRDGGRTLFYVSHAAGSVRKMCDRVIVLEQGRLAFDGGVDEGIKF
CCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHEEEEECCCEEECCCCCCCCEE
VKYDEEKATDEELGVDDTDDELGADI
EEECCHHCCHHHCCCCCCCHHCCCCC
>Mature Secondary Structure 
TYSASTSIVVDHATKDFTLRYHRTFKQMTVAALRRQSIADSFRAVDDVSFTVQQGESIG
CCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEE
LMGLNGSGKSTLLKLINGVMRPDSGRVLTRGRISGLIATGAGFHPQLTGRENVYLNAAVL
EEEECCCCHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEE
GMSEAETRRKFDDIAEFADIGKFLDSPVGHYSSGMFARLGFAVAIHVDSDIFLADEVLAV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEEEEEECCCEEEHHHHHHC
GDKPFKQKCLQRMQEIRDGGRTLFYVSHAAGSVRKMCDRVIVLEQGRLAFDGGVDEGIKF
CCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHEEEEECCCEEECCCCCCCCEE
VKYDEEKATDEELGVDDTDDELGADI
EEECCHHCCHHHCCCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]