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The map label for this gene is fadE25 [H]

Identifier: 119715626

GI number: 119715626

Start: 1466184

End: 1467356

Strand: Direct

Name: fadE25 [H]

Synonym: Noca_1390

Alternate gene names: 119715626

Gene position: 1466184-1467356 (Clockwise)

Preceding gene: 119715625

Following gene: 119715627

Centisome position: 29.41

GC content: 70.16

Gene sequence:

>1173_bases
ATGAGCTCCGAGTTCCCTCTCTTCGCCCTCTCCGAGGAGCACCAGGCCGTCCGCGAGGCGGCCCGAGCCGTGTGCGACGC
GAAGGTCGCACCGTTCGCCGCCGACGTCGACGAGCACGCCCGCTACCCGCGGGAGGCGGCCGAGGCCCTGCTGGCTGCGG
ACTTCCACGCCCCGCACATCCCGGAGCAGTACGGCGGTGCCGGCGCCGACGCGCTCGCCACCGTGATCATCATCGAGGAG
GTCGCCCGGGCCTGTGCCTCGAGCAGCCTGATCCCGGCGGTGAACAAGCTGGGGTCGCTGCCGATCCAGCTGGCCGGCTC
GGAGGAGCTGAAGGCGAAGTACCTGGGTGCGCTGGCGCGCGGTGAGGGCGGGTTCTCCTACTGCCTCTCCGAGCCGGACG
CGGGCTCGGACGCGGTGGGGATGAAGGCCCGAGCCGTGCGCGACGGGGACACCTGGGTGCTCAACGGCGTGAAGCGCTGG
ATCACCAACGCGGGCGAGTCGGAGTACTACACGGTGATGGCGGTGACGGACCCCGAGAAGCGCTCCCGGGGGATCAGCGC
GTTCGTGGTGGAGAAGAGCGACGAGGGCGTCTCCTTCGGTGCCCCGGAGAAGAAGCTCGGCATCAAGGGCTCTCCGACCC
GGGAGGTCTACCTGGACAACGTCCGCATCGGTGCGGACCGGATGATCGGGGCGGAGGGCGGCGGGTTCGAGATCGCGATG
CGCACCCTGGACCACACCCGGGTCACGATCGCGGCGCAGGCCGTCGGCATCGCCCAGGGGGCGTTGGACTACGCGCTGGG
CTACGCCCAGGAGCGCAAGCAGTTCGGGAAGCCGATCAGCGACTTCCAGGGCCTGCAGTTCCTGCTGGCCGACATGGGGA
TGAAGGTCGAGGCCGCGCGCCAGCTGACCTACGCGGCGGCCGGGAAGTCCGAGCGGGGCGACAGCGACCTGACGTTCTTC
GGGGCTGCGGCGAAGTGCTTCGCCTCCGACGTCGCCATGGAGGTCACCACCAACGCCGTCCAGGTCCTCGGCGGGTACGG
CTACACCCGGGACTACCCGGTCGAGCGGATGATGCGGGACGCGAAGATCACCCAGATCTACGAGGGCACCAACCAGGTGC
AGCGGATCGTGATGGCCCGCCAGCTCCTCGCCGGCGTCCAGTCCCAGCTCTGA

Upstream 100 bases:

>100_bases
CTAGCGCCGAACCGGCGAACGCCCGGCCGGGTTCTGCCCCGGCCGGGCGTTCGCGCGCCCGGCCGCGAACAGTCGCTGAC
CCGCGGATAGAGTCCGACAC

Downstream 100 bases:

>100_bases
CCTTCCGCCCGCCGGTGGACCAGCGCGGCGACCCGGTCGCGCATCCGCGGCGCCGTGGCCGGGTACCTCCTCGGAAGTCG
GATCGAGGAGGTCAGGACAT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSSEFPLFALSEEHQAVREAARAVCDAKVAPFAADVDEHARYPREAAEALLAADFHAPHIPEQYGGAGADALATVIIIEE
VARACASSSLIPAVNKLGSLPIQLAGSEELKAKYLGALARGEGGFSYCLSEPDAGSDAVGMKARAVRDGDTWVLNGVKRW
ITNAGESEYYTVMAVTDPEKRSRGISAFVVEKSDEGVSFGAPEKKLGIKGSPTREVYLDNVRIGADRMIGAEGGGFEIAM
RTLDHTRVTIAAQAVGIAQGALDYALGYAQERKQFGKPISDFQGLQFLLADMGMKVEAARQLTYAAAGKSERGDSDLTFF
GAAAKCFASDVAMEVTTNAVQVLGGYGYTRDYPVERMMRDAKITQIYEGTNQVQRIVMARQLLAGVQSQL

Sequences:

>Translated_390_residues
MSSEFPLFALSEEHQAVREAARAVCDAKVAPFAADVDEHARYPREAAEALLAADFHAPHIPEQYGGAGADALATVIIIEE
VARACASSSLIPAVNKLGSLPIQLAGSEELKAKYLGALARGEGGFSYCLSEPDAGSDAVGMKARAVRDGDTWVLNGVKRW
ITNAGESEYYTVMAVTDPEKRSRGISAFVVEKSDEGVSFGAPEKKLGIKGSPTREVYLDNVRIGADRMIGAEGGGFEIAM
RTLDHTRVTIAAQAVGIAQGALDYALGYAQERKQFGKPISDFQGLQFLLADMGMKVEAARQLTYAAAGKSERGDSDLTFF
GAAAKCFASDVAMEVTTNAVQVLGGYGYTRDYPVERMMRDAKITQIYEGTNQVQRIVMARQLLAGVQSQL
>Mature_389_residues
SSEFPLFALSEEHQAVREAARAVCDAKVAPFAADVDEHARYPREAAEALLAADFHAPHIPEQYGGAGADALATVIIIEEV
ARACASSSLIPAVNKLGSLPIQLAGSEELKAKYLGALARGEGGFSYCLSEPDAGSDAVGMKARAVRDGDTWVLNGVKRWI
TNAGESEYYTVMAVTDPEKRSRGISAFVVEKSDEGVSFGAPEKKLGIKGSPTREVYLDNVRIGADRMIGAEGGGFEIAMR
TLDHTRVTIAAQAVGIAQGALDYALGYAQERKQFGKPISDFQGLQFLLADMGMKVEAARQLTYAAAGKSERGDSDLTFFG
AAAKCFASDVAMEVTTNAVQVLGGYGYTRDYPVERMMRDAKITQIYEGTNQVQRIVMARQLLAGVQSQL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=382, Percent_Identity=42.6701570680628, Blast_Score=290, Evalue=1e-78,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=38.9920424403183, Blast_Score=289, Evalue=3e-78,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=38.9920424403183, Blast_Score=289, Evalue=3e-78,
Organism=Homo sapiens, GI4501859, Length=378, Percent_Identity=38.0952380952381, Blast_Score=275, Evalue=5e-74,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=36.2433862433862, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI21361497, Length=359, Percent_Identity=37.6044568245125, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=34.6456692913386, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI4557235, Length=331, Percent_Identity=36.2537764350453, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI76496475, Length=331, Percent_Identity=36.2537764350453, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI226958414, Length=328, Percent_Identity=36.5853658536585, Blast_Score=201, Evalue=9e-52,
Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=29.8941798941799, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI4503943, Length=389, Percent_Identity=27.7634961439589, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI7669494, Length=369, Percent_Identity=27.3712737127371, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI38505218, Length=282, Percent_Identity=28.0141843971631, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI211971008, Length=286, Percent_Identity=29.7202797202797, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI48976061, Length=286, Percent_Identity=29.7202797202797, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI87081958, Length=385, Percent_Identity=31.1688311688312, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=27.9683377308707, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI87082384, Length=265, Percent_Identity=25.2830188679245, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081702, Length=409, Percent_Identity=24.9388753056235, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=40.6332453825858, Blast_Score=301, Evalue=5e-82,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=40.5759162303665, Blast_Score=297, Evalue=6e-81,
Organism=Caenorhabditis elegans, GI17534899, Length=380, Percent_Identity=40, Blast_Score=291, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI17506239, Length=378, Percent_Identity=37.3015873015873, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17508101, Length=379, Percent_Identity=39.3139841688654, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=36.6754617414248, Blast_Score=238, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17533517, Length=380, Percent_Identity=34.4736842105263, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI71990804, Length=273, Percent_Identity=40.2930402930403, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71985184, Length=359, Percent_Identity=34.8189415041783, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI32563615, Length=239, Percent_Identity=40.1673640167364, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71982178, Length=279, Percent_Identity=35.1254480286738, Blast_Score=181, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=30.6666666666667, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=30.3191489361702, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=34.0350877192982, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17534353, Length=379, Percent_Identity=26.9129287598945, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=31.404958677686, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17562446, Length=349, Percent_Identity=28.9398280802292, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI86563383, Length=273, Percent_Identity=30.4029304029304, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI86563381, Length=273, Percent_Identity=30.4029304029304, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24660351, Length=385, Percent_Identity=40, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=41.5343915343915, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=40.3183023872679, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24666513, Length=377, Percent_Identity=35.8090185676393, Blast_Score=238, Evalue=6e-63,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=36.5535248041775, Blast_Score=218, Evalue=8e-57,
Organism=Drosophila melanogaster, GI281363737, Length=368, Percent_Identity=34.5108695652174, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI19920834, Length=378, Percent_Identity=27.5132275132275, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41724; Mature: 41592

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEFPLFALSEEHQAVREAARAVCDAKVAPFAADVDEHARYPREAAEALLAADFHAPHI
CCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCC
PEQYGGAGADALATVIIIEEVARACASSSLIPAVNKLGSLPIQLAGSEELKAKYLGALAR
CHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHC
GEGGFSYCLSEPDAGSDAVGMKARAVRDGDTWVLNGVKRWITNAGESEYYTVMAVTDPEK
CCCCCEEECCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEECHHH
RSRGISAFVVEKSDEGVSFGAPEKKLGIKGSPTREVYLDNVRIGADRMIGAEGGGFEIAM
HHCCCEEEEEECCCCCCCCCCCCHHCCCCCCCCCEEEECCEEECCCCEECCCCCCEEEEE
RTLDHTRVTIAAQAVGIAQGALDYALGYAQERKQFGKPISDFQGLQFLLADMGMKVEAAR
EECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHH
QLTYAAAGKSERGDSDLTFFGAAAKCFASDVAMEVTTNAVQVLGGYGYTRDYPVERMMRD
HHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AKITQIYEGTNQVQRIVMARQLLAGVQSQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSEFPLFALSEEHQAVREAARAVCDAKVAPFAADVDEHARYPREAAEALLAADFHAPHI
CCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCC
PEQYGGAGADALATVIIIEEVARACASSSLIPAVNKLGSLPIQLAGSEELKAKYLGALAR
CHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHC
GEGGFSYCLSEPDAGSDAVGMKARAVRDGDTWVLNGVKRWITNAGESEYYTVMAVTDPEK
CCCCCEEECCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEECHHH
RSRGISAFVVEKSDEGVSFGAPEKKLGIKGSPTREVYLDNVRIGADRMIGAEGGGFEIAM
HHCCCEEEEEECCCCCCCCCCCCHHCCCCCCCCCEEEECCEEECCCCEECCCCCCEEEEE
RTLDHTRVTIAAQAVGIAQGALDYALGYAQERKQFGKPISDFQGLQFLLADMGMKVEAAR
EECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHH
QLTYAAAGKSERGDSDLTFFGAAAKCFASDVAMEVTTNAVQVLGGYGYTRDYPVERMMRD
HHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AKITQIYEGTNQVQRIVMARQLLAGVQSQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]