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The map label for this gene is phoR [H]

Identifier: 119715576

GI number: 119715576

Start: 1412168

End: 1414216

Strand: Direct

Name: phoR [H]

Synonym: Noca_1340

Alternate gene names: 119715576

Gene position: 1412168-1414216 (Clockwise)

Preceding gene: 119715574

Following gene: 119715577

Centisome position: 28.32

GC content: 71.89

Gene sequence:

>2049_bases
GTGGGCGCTCGGGAGGAGTGGTTCACCGTGGCGAGGTCGTGGGTCGTGCGCGTCACCGGCCTGCTCGCGCTGATGGCCCT
GGTGGGCGTCACCGCCGTCCAGGGGGCGCCCGACGGTGGCCGGGCGATCGGGATCTGGCCGGTCGGCCTGGCGACGGGCT
GCTTCATGGTGGCCCCGCGCCCGCGGACCCCGGTGCTGGTCGTCCTCGTGGCACTGCTCGCGACCGGCAGCATCTGGGTG
GGCGGCCGCGGCCCGGACGTCGCGGTCGGCCTCGGTGTCGGGCTCGCTGTCGGCGCCTGGCTGATGTGGCGGGTCCTGGC
GCAGGGTCGCCGCGAGCGCCCCATGCTGCACACCAGCGCGGACCTGGCCCGCTTCCTCGGCGGGGCGTTCGCGAGCGCAC
TCGTGGTCGCAGCGGCAGCGGCCGTGACCAGCTCGGTGACGGGCTGGGGCGACCCGGGCCTCCTCGCCCTCGCCGTCGGG
ACCTCGAACCTGAGCGCTCAGTCCGCCGTCGTCCCGTTCTTCTGCCGACTGCGCAACCATGCACCGCTCGCCGGACCCAC
GGAGCGGCTCGCCCAGTGGCTGCTGATCCTGACGATCACCCCGGCGGTCTTCGTTCCCCAGGACTTCCCGTCGGTCGTCT
TCCTCGTGGTCCCGGTGCTGGTGTGGGGCGCAATGCGCAGCAGCCCCTACGAGGCGCTCGCCCAGCTGATCACGACGCTG
GGCTTCGCGATCCCGCTCACCACCTGGGGCCACGGCCCGTTCGCCGACGCCGGGCCGCGCTTCCAGATGTCGGTGGACGG
CCAGGGCATCCTGCTGGCGACGTACGGCGTGGTCTGCGCGCTGGTCGTGATCCCGTTGGTGCTGACGGTGAGCGAGCAGC
TCGAGCACGCCCGGCAGGCGGCGGCCGAGCGCGACAAGGTCCAGAACATCGTCAACGGGACCGCCGGCGTGGCGATCATC
GGCACCGACGAGCACGGCCGGGTGACCCTCTTCAACCCCGGCGCGGAGCGGCTGCTCGGCTACCGGGCCGACGAGGTCCT
CGGCCGGCTGATCCGAGAGTTCCACTCCGCGGACGCGATCTCCGAGAAGGCTGCGGAGCTCGGCGTGGCCGCCGACTTCG
GCGTGGTTGCGAGGTCGCTGATCGGCCAGGGCGCCACCGATATGCGCTTCCTGCGCAAGGACGGCGAGGAGCGCAGCCAC
TCGATGTCGCTGAACCGGATCGAGGACGACCGTGGTCGGGTGATCGGCTACGTCAGCACCTCGGAGGACATCACCGAGCG
GGTGGAGGCCGAGGGCCGGCTGGTGGAGGCGTTGGAGACCGAGCGCCAGGCGGTCGAGCGGCTGCGGGAGGTGGACCAGG
TCAAGGACGCGTTCGTCTCGAGCGTCAGCCACGAGCTGCGCACCCCGATCACCAGCATCCTCGGCTACACCGAGATGCTC
GAGGACGGGGTGTACGGCGACCTCGGGCGCGAGCAGCTCGACGCGGTGCGTCGGGTCGCGGCCAACAGCACCCGCCTGCT
CTCGCTGATCAACGACCTGCTCACGCTCTCCCGGGTCCAGGAGGACGAGATCGGCATCGTCGACCGCGTCTTCGACCTGC
GCTCGGTGGTCTCGGCCGGGACGGCCGTCGTCGCACCGACGCTCGAGCGGAGGTCGCTCGAGCTGACCGCGGAGCTGCCC
GACGAGCCGGTCCCGTTCCTCGGCGACCGAGACATGCTCGAACGGGTGGTGATCAACCTGGCCGGCAACGCCGCGAAGTT
CACCCCCGAGGGCGGCCGCATCGGGGTGCGGCTGCTGGTCGGGCCGGAGGAGTCGGTGATCGAGGTCAGCGACACCGGCA
TCGGCATCCCGCACCAGGAGCAGGAGCGGCTGTTCAGCCGGTTCTTCCGGTCCTCCCTCGCCCAGGAGCGAGCGATCCCG
GGCAGTGGACTAGGCCTCTCGATCGCGCACGCGATCGTCGAGAAGCACGGTGGCACCATGAGTGTCGACTCCGAGCCGGG
GGAGGGTACGACGTTCCGGGTCCACCTCCCGGCCCTCACGGCGCCCTGA

Upstream 100 bases:

>100_bases
GCTCTTCGACGAAGTCACCGGGCCAACGTAGTGCGCCGTCGGCAGGTCGCCCGGCAGGCGGCGAGTCGGGGCGTCAAGAT
GGGCGCAGGGCGGGCGCAGG

Downstream 100 bases:

>100_bases
CGCGCACCGCGACGCAGCCACGCCACCGGAATATCCAACTTTCAACGACCGTTGGGCCTGGTGTTCCGACACCGACAGCA
GGAGGTGGGCCGCATGCCCG

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 681

Protein sequence:

>682_residues
MGAREEWFTVARSWVVRVTGLLALMALVGVTAVQGAPDGGRAIGIWPVGLATGCFMVAPRPRTPVLVVLVALLATGSIWV
GGRGPDVAVGLGVGLAVGAWLMWRVLAQGRRERPMLHTSADLARFLGGAFASALVVAAAAAVTSSVTGWGDPGLLALAVG
TSNLSAQSAVVPFFCRLRNHAPLAGPTERLAQWLLILTITPAVFVPQDFPSVVFLVVPVLVWGAMRSSPYEALAQLITTL
GFAIPLTTWGHGPFADAGPRFQMSVDGQGILLATYGVVCALVVIPLVLTVSEQLEHARQAAAERDKVQNIVNGTAGVAII
GTDEHGRVTLFNPGAERLLGYRADEVLGRLIREFHSADAISEKAAELGVAADFGVVARSLIGQGATDMRFLRKDGEERSH
SMSLNRIEDDRGRVIGYVSTSEDITERVEAEGRLVEALETERQAVERLREVDQVKDAFVSSVSHELRTPITSILGYTEML
EDGVYGDLGREQLDAVRRVAANSTRLLSLINDLLTLSRVQEDEIGIVDRVFDLRSVVSAGTAVVAPTLERRSLELTAELP
DEPVPFLGDRDMLERVVINLAGNAAKFTPEGGRIGVRLLVGPEESVIEVSDTGIGIPHQEQERLFSRFFRSSLAQERAIP
GSGLGLSIAHAIVEKHGGTMSVDSEPGEGTTFRVHLPALTAP

Sequences:

>Translated_682_residues
MGAREEWFTVARSWVVRVTGLLALMALVGVTAVQGAPDGGRAIGIWPVGLATGCFMVAPRPRTPVLVVLVALLATGSIWV
GGRGPDVAVGLGVGLAVGAWLMWRVLAQGRRERPMLHTSADLARFLGGAFASALVVAAAAAVTSSVTGWGDPGLLALAVG
TSNLSAQSAVVPFFCRLRNHAPLAGPTERLAQWLLILTITPAVFVPQDFPSVVFLVVPVLVWGAMRSSPYEALAQLITTL
GFAIPLTTWGHGPFADAGPRFQMSVDGQGILLATYGVVCALVVIPLVLTVSEQLEHARQAAAERDKVQNIVNGTAGVAII
GTDEHGRVTLFNPGAERLLGYRADEVLGRLIREFHSADAISEKAAELGVAADFGVVARSLIGQGATDMRFLRKDGEERSH
SMSLNRIEDDRGRVIGYVSTSEDITERVEAEGRLVEALETERQAVERLREVDQVKDAFVSSVSHELRTPITSILGYTEML
EDGVYGDLGREQLDAVRRVAANSTRLLSLINDLLTLSRVQEDEIGIVDRVFDLRSVVSAGTAVVAPTLERRSLELTAELP
DEPVPFLGDRDMLERVVINLAGNAAKFTPEGGRIGVRLLVGPEESVIEVSDTGIGIPHQEQERLFSRFFRSSLAQERAIP
GSGLGLSIAHAIVEKHGGTMSVDSEPGEGTTFRVHLPALTAP
>Mature_681_residues
GAREEWFTVARSWVVRVTGLLALMALVGVTAVQGAPDGGRAIGIWPVGLATGCFMVAPRPRTPVLVVLVALLATGSIWVG
GRGPDVAVGLGVGLAVGAWLMWRVLAQGRRERPMLHTSADLARFLGGAFASALVVAAAAAVTSSVTGWGDPGLLALAVGT
SNLSAQSAVVPFFCRLRNHAPLAGPTERLAQWLLILTITPAVFVPQDFPSVVFLVVPVLVWGAMRSSPYEALAQLITTLG
FAIPLTTWGHGPFADAGPRFQMSVDGQGILLATYGVVCALVVIPLVLTVSEQLEHARQAAAERDKVQNIVNGTAGVAIIG
TDEHGRVTLFNPGAERLLGYRADEVLGRLIREFHSADAISEKAAELGVAADFGVVARSLIGQGATDMRFLRKDGEERSHS
MSLNRIEDDRGRVIGYVSTSEDITERVEAEGRLVEALETERQAVERLREVDQVKDAFVSSVSHELRTPITSILGYTEMLE
DGVYGDLGREQLDAVRRVAANSTRLLSLINDLLTLSRVQEDEIGIVDRVFDLRSVVSAGTAVVAPTLERRSLELTAELPD
EPVPFLGDRDMLERVVINLAGNAAKFTPEGGRIGVRLLVGPEESVIEVSDTGIGIPHQEQERLFSRFFRSSLAQERAIPG
SGLGLSIAHAIVEKHGGTMSVDSEPGEGTTFRVHLPALTAP

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=36.328125, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789149, Length=261, Percent_Identity=34.4827586206897, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1786912, Length=252, Percent_Identity=34.9206349206349, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788549, Length=399, Percent_Identity=25.062656641604, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=31.7596566523605, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=33.0472103004292, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788713, Length=268, Percent_Identity=29.8507462686567, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI87081816, Length=278, Percent_Identity=29.4964028776978, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI48994928, Length=277, Percent_Identity=27.7978339350181, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=29.5719844357977, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786783, Length=272, Percent_Identity=29.4117647058824, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=29.6610169491525, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=29.0909090909091, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790861, Length=248, Percent_Identity=28.6290322580645, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788279, Length=231, Percent_Identity=25.5411255411255, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787894, Length=239, Percent_Identity=25.5230125523013, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790300, Length=378, Percent_Identity=24.6031746031746, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=237, Percent_Identity=27.4261603375527, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72789; Mature: 72657

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAREEWFTVARSWVVRVTGLLALMALVGVTAVQGAPDGGRAIGIWPVGLATGCFMVAPR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHCCEEEECCC
PRTPVLVVLVALLATGSIWVGGRGPDVAVGLGVGLAVGAWLMWRVLAQGRRERPMLHTSA
CCCHHHHHHHHHHHCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
DLARFLGGAFASALVVAAAAAVTSSVTGWGDPGLLALAVGTSNLSAQSAVVPFFCRLRNH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
APLAGPTERLAQWLLILTITPAVFVPQDFPSVVFLVVPVLVWGAMRSSPYEALAQLITTL
CCCCCCHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GFAIPLTTWGHGPFADAGPRFQMSVDGQGILLATYGVVCALVVIPLVLTVSEQLEHARQA
HHHHHCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAERDKVQNIVNGTAGVAIIGTDEHGRVTLFNPGAERLLGYRADEVLGRLIREFHSADAI
HHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHH
SEKAAELGVAADFGVVARSLIGQGATDMRFLRKDGEERSHSMSLNRIEDDRGRVIGYVST
HHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCHHCCCCCCCCEEEEEEC
SEDITERVEAEGRLVEALETERQAVERLREVDQVKDAFVSSVSHELRTPITSILGYTEML
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDGVYGDLGREQLDAVRRVAANSTRLLSLINDLLTLSRVQEDEIGIVDRVFDLRSVVSAG
HCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
TAVVAPTLERRSLELTAELPDEPVPFLGDRDMLERVVINLAGNAAKFTPEGGRIGVRLLV
CEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCEEEEEEE
GPEESVIEVSDTGIGIPHQEQERLFSRFFRSSLAQERAIPGSGLGLSIAHAIVEKHGGTM
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEE
SVDSEPGEGTTFRVHLPALTAP
EECCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
GAREEWFTVARSWVVRVTGLLALMALVGVTAVQGAPDGGRAIGIWPVGLATGCFMVAPR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHCCEEEECCC
PRTPVLVVLVALLATGSIWVGGRGPDVAVGLGVGLAVGAWLMWRVLAQGRRERPMLHTSA
CCCHHHHHHHHHHHCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
DLARFLGGAFASALVVAAAAAVTSSVTGWGDPGLLALAVGTSNLSAQSAVVPFFCRLRNH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
APLAGPTERLAQWLLILTITPAVFVPQDFPSVVFLVVPVLVWGAMRSSPYEALAQLITTL
CCCCCCHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GFAIPLTTWGHGPFADAGPRFQMSVDGQGILLATYGVVCALVVIPLVLTVSEQLEHARQA
HHHHHCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAERDKVQNIVNGTAGVAIIGTDEHGRVTLFNPGAERLLGYRADEVLGRLIREFHSADAI
HHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHH
SEKAAELGVAADFGVVARSLIGQGATDMRFLRKDGEERSHSMSLNRIEDDRGRVIGYVST
HHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCHHCCCCCCCCEEEEEEC
SEDITERVEAEGRLVEALETERQAVERLREVDQVKDAFVSSVSHELRTPITSILGYTEML
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDGVYGDLGREQLDAVRRVAANSTRLLSLINDLLTLSRVQEDEIGIVDRVFDLRSVVSAG
HCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
TAVVAPTLERRSLELTAELPDEPVPFLGDRDMLERVVINLAGNAAKFTPEGGRIGVRLLV
CEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCEEEEEEE
GPEESVIEVSDTGIGIPHQEQERLFSRFFRSSLAQERAIPGSGLGLSIAHAIVEKHGGTM
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEE
SVDSEPGEGTTFRVHLPALTAP
EECCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]