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The map label for this gene is lss [H]

Identifier: 119715506

GI number: 119715506

Start: 1344865

End: 1346124

Strand: Direct

Name: lss [H]

Synonym: Noca_1270

Alternate gene names: 119715506

Gene position: 1344865-1346124 (Clockwise)

Preceding gene: 119715505

Following gene: 119715507

Centisome position: 26.97

GC content: 72.06

Gene sequence:

>1260_bases
GTGCGTCTCTTCCCCCGTACCGCACGCCATCGCCTGACGGCAGCCACCGCGGCCTGCACGCTGGCGATCGGTGCGCTGGC
CGTTCCCCTCGCGAACGCCGAGCCGAAGGACCTCAAGCACAAGCAGCAGCAGGCCCAGCAGCAGGTCAAGAGCGCCGAGC
AGGACCTCGACGAGTCCAGCGCGCGGCTGCGCCGGGCCCAGGGCGCGCTGGACCGGGCGATCCACGAGCTCTCGACCGCC
CGTGGCGAGCTGCGGGCCGCCAGCGCCCGCCTCCAGGCCGCCGAGATCCGCGACCGCGAGATGCAGGCCCGCCTCGAGAC
CGCCGAGCAACGGCTCGTCGACGCGCAGACCGACCTCGCCGACGGCCAGGCGGCCCTCGACGACCAGCGGCTGAAGCTGA
CCGACACGGTCACCGACATCTACGAGCAGGGCGACCCGCAGCTGCTCGCGTTCGCCACGCTGCTGGAGTCGCGGAGCACC
GCCGACCTGACCCGCCAGTCGGCGCTCAACGACGTGATCGTGGGTCGTGAGGCCCGGGCGTACGACGACCTCCACGCCGC
CGAGGTGCTGCTCCAGGTCCGCGAGAACCAGGTGCAGGCCGCCCGCGACGACGTCGAGGTGCAACGCCAGGCTGCCGCCG
AGCACCTGGTCACGATGGAGACCCTGCACCAGGAGGCGCGCGCCGCCCGCGACAAGGTGATGACCCTGGTGGAGACCCGG
CGCGACGCGCGCGCCGGCGCGATCCGGGCCCGCCAGCAGGACCGCAAGGAGCTGCAGGAGGCCAAGCGCCGCGAGAACCA
CGTCCGCCAGCTGATCCTGGCGGCCGCCCGCCGCGCCAAGGGCGGCTACACCGGGCCGACCAACGGCCTGATGATCCGGC
CCGTCCCCGGCGTGGTCACCTCGCCGTTCGGCTACCGGATCCACCCGATCTACGGCTACTGGGGTCTGCACGACGGCACC
GACTTCGGGGTCTCCTGCGGCGAGGGGATGCGCGCGGTGGCCTCGGGCACCGTGATCGCGAAGTACTTCTCGTCGGTCTA
CGGCAACCGCCTCTACCTCAGCCTGGGCCAGATCAACGGCAAGAACGTCACCGCGGTCTACAACCACGCCACCGGCTACC
GGGTCGGCGTCGGCGACCGCGTCAGCCAGGGCGAGATCGTCGGGTACGTCGGCTCCACGGGCTGGTCGACCGGCTGCCAC
CTGCACTTCTCGATCCTGGTGAACGGCACCGCCGTGGACCCAATGAACTGGCTGCCCTGA

Upstream 100 bases:

>100_bases
CTGCTGCCGACACTCGTGCTGACGCGCAAATACCTCAAAGTCTGACGCGCGCACGTTACCGTCGAGGAGTTCTCTTCCCC
GAACACGTGAAGGCAGACCG

Downstream 100 bases:

>100_bases
CCCCGCCGGAACTTCTCGGCCCAGGGGTCTCCCGCTGGACGATCTTCTGTGATGGACTCCCTCTCCTCGGGGGAATGACG
AGAGGGAGCGATACATGAAG

Product: peptidase M23B

Products: NA

Alternate protein names: Glycyl-glycine endopeptidase [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRLFPRTARHRLTAATAACTLAIGALAVPLANAEPKDLKHKQQQAQQQVKSAEQDLDESSARLRRAQGALDRAIHELSTA
RGELRAASARLQAAEIRDREMQARLETAEQRLVDAQTDLADGQAALDDQRLKLTDTVTDIYEQGDPQLLAFATLLESRST
ADLTRQSALNDVIVGREARAYDDLHAAEVLLQVRENQVQAARDDVEVQRQAAAEHLVTMETLHQEARAARDKVMTLVETR
RDARAGAIRARQQDRKELQEAKRRENHVRQLILAAARRAKGGYTGPTNGLMIRPVPGVVTSPFGYRIHPIYGYWGLHDGT
DFGVSCGEGMRAVASGTVIAKYFSSVYGNRLYLSLGQINGKNVTAVYNHATGYRVGVGDRVSQGEIVGYVGSTGWSTGCH
LHFSILVNGTAVDPMNWLP

Sequences:

>Translated_419_residues
MRLFPRTARHRLTAATAACTLAIGALAVPLANAEPKDLKHKQQQAQQQVKSAEQDLDESSARLRRAQGALDRAIHELSTA
RGELRAASARLQAAEIRDREMQARLETAEQRLVDAQTDLADGQAALDDQRLKLTDTVTDIYEQGDPQLLAFATLLESRST
ADLTRQSALNDVIVGREARAYDDLHAAEVLLQVRENQVQAARDDVEVQRQAAAEHLVTMETLHQEARAARDKVMTLVETR
RDARAGAIRARQQDRKELQEAKRRENHVRQLILAAARRAKGGYTGPTNGLMIRPVPGVVTSPFGYRIHPIYGYWGLHDGT
DFGVSCGEGMRAVASGTVIAKYFSSVYGNRLYLSLGQINGKNVTAVYNHATGYRVGVGDRVSQGEIVGYVGSTGWSTGCH
LHFSILVNGTAVDPMNWLP
>Mature_419_residues
MRLFPRTARHRLTAATAACTLAIGALAVPLANAEPKDLKHKQQQAQQQVKSAEQDLDESSARLRRAQGALDRAIHELSTA
RGELRAASARLQAAEIRDREMQARLETAEQRLVDAQTDLADGQAALDDQRLKLTDTVTDIYEQGDPQLLAFATLLESRST
ADLTRQSALNDVIVGREARAYDDLHAAEVLLQVRENQVQAARDDVEVQRQAAAEHLVTMETLHQEARAARDKVMTLVETR
RDARAGAIRARQQDRKELQEAKRRENHVRQLILAAARRAKGGYTGPTNGLMIRPVPGVVTSPFGYRIHPIYGYWGLHDGT
DFGVSCGEGMRAVASGTVIAKYFSSVYGNRLYLSLGQINGKNVTAVYNHATGYRVGVGDRVSQGEIVGYVGSTGWSTGCH
LHFSILVNGTAVDPMNWLP

Specific function: Lyses staphylococcal cells by hydrolyzing the polyglycine interpeptide bridges of the peptidoglycan [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

Organism=Escherichia coli, GI87082297, Length=260, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047
- InterPro:   IPR002886
- InterPro:   IPR003646
- InterPro:   IPR013667 [H]

Pfam domain/function: PF01551 Peptidase_M23; PF08460 SH3_5 [H]

EC number: =3.4.24.75 [H]

Molecular weight: Translated: 46005; Mature: 46005

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFPRTARHRLTAATAACTLAIGALAVPLANAEPKDLKHKQQQAQQQVKSAEQDLDESS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARLRRAQGALDRAIHELSTARGELRAASARLQAAEIRDREMQARLETAEQRLVDAQTDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DGQAALDDQRLKLTDTVTDIYEQGDPQLLAFATLLESRSTADLTRQSALNDVIVGREARA
CCCHHCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHH
YDDLHAAEVLLQVRENQVQAARDDVEVQRQAAAEHLVTMETLHQEARAARDKVMTLVETR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDARAGAIRARQQDRKELQEAKRRENHVRQLILAAARRAKGGYTGPTNGLMIRPVPGVVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEE
SPFGYRIHPIYGYWGLHDGTDFGVSCGEGMRAVASGTVIAKYFSSVYGNRLYLSLGQING
CCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCEEEEEEECCCC
KNVTAVYNHATGYRVGVGDRVSQGEIVGYVGSTGWSTGCHLHFSILVNGTAVDPMNWLP
CEEEEEEECCCCEEECCCCCCCCCCEEEEECCCCCCCCCEEEEEEEEECCEECCCCCCC
>Mature Secondary Structure
MRLFPRTARHRLTAATAACTLAIGALAVPLANAEPKDLKHKQQQAQQQVKSAEQDLDESS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARLRRAQGALDRAIHELSTARGELRAASARLQAAEIRDREMQARLETAEQRLVDAQTDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DGQAALDDQRLKLTDTVTDIYEQGDPQLLAFATLLESRSTADLTRQSALNDVIVGREARA
CCCHHCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHH
YDDLHAAEVLLQVRENQVQAARDDVEVQRQAAAEHLVTMETLHQEARAARDKVMTLVETR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDARAGAIRARQQDRKELQEAKRRENHVRQLILAAARRAKGGYTGPTNGLMIRPVPGVVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEE
SPFGYRIHPIYGYWGLHDGTDFGVSCGEGMRAVASGTVIAKYFSSVYGNRLYLSLGQING
CCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCEEEEEEECCCC
KNVTAVYNHATGYRVGVGDRVSQGEIVGYVGSTGWSTGCHLHFSILVNGTAVDPMNWLP
CEEEEEEECCCCEEECCCCCCCCCCEEEEECCCCCCCCCEEEEEEEEECCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3547405; 9106216 [H]