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The map label for this gene is phoP [H]

Identifier: 119715476

GI number: 119715476

Start: 1315692

End: 1316396

Strand: Direct

Name: phoP [H]

Synonym: Noca_1240

Alternate gene names: 119715476

Gene position: 1315692-1316396 (Clockwise)

Preceding gene: 119715475

Following gene: 119715477

Centisome position: 26.39

GC content: 70.64

Gene sequence:

>705_bases
ATGCTCGCTCCCATGGCGCAACGAGTTCTGGTGGTCGAGGACGAGGAGGACATCGCGTTCCCCCTCGTCCGAACGCTGGA
GCGCGAAGGTTACGACGTCTCGTGGGTGGACAGCGGCCAGAAGGCCCTGGACACCATGGCGACCGCACCCGAGGTCGTGA
TCCTCGACCTCGGGCTCCCGGACATCGACGGCCTCGAGGTGTGCCGCCGGGCCCGGGAGGCGGGGTTCGAGGGCGCGATC
ATGATCGTCACCGCCCGGGCGGGCGAGCTGGACCGGGTGGTCGGGCTCGACTACGGGGCCGACGACTACCTGGCCAAGCC
GTTCGGCCTGGCCGAGCTGCAGGCGCGCGTGCGCGCCCTGTTGCGCCGTACCTCCTCCGGCTCGGCCACGGCCGAGGGCG
CGAAGCCCGACGGGCTGCGCATCGACGTGGACGCCCGGCGGGTCTACGCCGGCGACGAGGAGGTCCCGCTCACCGGCAAG
GAGTTCGAGGTGTTGAACATCCTCGCCGCCAACCGGGACAAGGTCGTCTCGCGCGGCCGGCTGATGGCCGACGTGTGGGA
CGAGAACTGGTACGGCTCGACGAAGACGCTCGACGTCACCATCGGACGGCTGCGCCAGAAGCTCGAGAGCGTCGGCGTGA
CCGACAGGGTGGTGGCCGTTCGAGGTGTGGGGTTCCGCCTCGAGGGCGGCACCCCAGATGCGTGA

Upstream 100 bases:

>100_bases
CCCCCGACCAGCCGGAAGCGCCGGTCCCCGGTGCGGCCACCCGCGCGACCGAGGGGAGCGAACGTTGAGTACCGCCCTCG
GGCCGGGTGCCGCGGGCCCT

Downstream 100 bases:

>100_bases
ACGCCTGACGATCGCCTTCGTCGTCCTCACCATCGTCCTGCTCCTCGGCGCCGGCGCGGTGCGGACGTTCGTGCTGCGCG
ACCTGATCCAGGAGCAGGAG

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLAPMAQRVLVVEDEEDIAFPLVRTLEREGYDVSWVDSGQKALDTMATAPEVVILDLGLPDIDGLEVCRRAREAGFEGAI
MIVTARAGELDRVVGLDYGADDYLAKPFGLAELQARVRALLRRTSSGSATAEGAKPDGLRIDVDARRVYAGDEEVPLTGK
EFEVLNILAANRDKVVSRGRLMADVWDENWYGSTKTLDVTIGRLRQKLESVGVTDRVVAVRGVGFRLEGGTPDA

Sequences:

>Translated_234_residues
MLAPMAQRVLVVEDEEDIAFPLVRTLEREGYDVSWVDSGQKALDTMATAPEVVILDLGLPDIDGLEVCRRAREAGFEGAI
MIVTARAGELDRVVGLDYGADDYLAKPFGLAELQARVRALLRRTSSGSATAEGAKPDGLRIDVDARRVYAGDEEVPLTGK
EFEVLNILAANRDKVVSRGRLMADVWDENWYGSTKTLDVTIGRLRQKLESVGVTDRVVAVRGVGFRLEGGTPDA
>Mature_234_residues
MLAPMAQRVLVVEDEEDIAFPLVRTLEREGYDVSWVDSGQKALDTMATAPEVVILDLGLPDIDGLEVCRRAREAGFEGAI
MIVTARAGELDRVVGLDYGADDYLAKPFGLAELQARVRALLRRTSSGSATAEGAKPDGLRIDVDARRVYAGDEEVPLTGK
EFEVLNILAANRDKVVSRGRLMADVWDENWYGSTKTLDVTIGRLRQKLESVGVTDRVVAVRGVGFRLEGGTPDA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=40.7239819004525, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=37.6681614349776, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=37.1681415929204, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=35.9649122807018, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=37.5565610859729, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=34.6846846846847, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=35.3982300884956, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=34.8214285714286, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=36.6071428571429, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=33.7899543378995, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=33.6170212765957, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI2367329, Length=211, Percent_Identity=34.5971563981043, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=33.0434782608696, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=27.5109170305677, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=30.8333333333333, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25475; Mature: 25475

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAPMAQRVLVVEDEEDIAFPLVRTLEREGYDVSWVDSGQKALDTMATAPEVVILDLGLP
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCEEEEECCCC
DIDGLEVCRRAREAGFEGAIMIVTARAGELDRVVGLDYGADDYLAKPFGLAELQARVRAL
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCCCHHCCCCCHHHHHHHHHHH
LRRTSSGSATAEGAKPDGLRIDVDARRVYAGDEEVPLTGKEFEVLNILAANRDKVVSRGR
HHHCCCCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHCCC
LMADVWDENWYGSTKTLDVTIGRLRQKLESVGVTDRVVAVRGVGFRLEGGTPDA
EEEEECCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCCCC
>Mature Secondary Structure
MLAPMAQRVLVVEDEEDIAFPLVRTLEREGYDVSWVDSGQKALDTMATAPEVVILDLGLP
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCEEEEECCCC
DIDGLEVCRRAREAGFEGAIMIVTARAGELDRVVGLDYGADDYLAKPFGLAELQARVRAL
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCCCHHCCCCCHHHHHHHHHHH
LRRTSSGSATAEGAKPDGLRIDVDARRVYAGDEEVPLTGKEFEVLNILAANRDKVVSRGR
HHHCCCCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHCCC
LMADVWDENWYGSTKTLDVTIGRLRQKLESVGVTDRVVAVRGVGFRLEGGTPDA
EEEEECCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]