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The map label for this gene is caiE [C]

Identifier: 119715401

GI number: 119715401

Start: 1236972

End: 1237487

Strand: Reverse

Name: caiE [C]

Synonym: Noca_1164

Alternate gene names: 119715401

Gene position: 1237487-1236972 (Counterclockwise)

Preceding gene: 119715402

Following gene: 119715400

Centisome position: 24.82

GC content: 70.93

Gene sequence:

>516_bases
GTGAGGCTCCGTCTCGAACATCACCTGCCGCGTGTCCACCCGGAGGCCTGGGTCGCGCCCACAGCCGTCCTTGCCGGAGC
GGTCACGGTGGAGCGTGGCGCCAGCGTGTGGTTCGGCAGCGTGATCCGCGCTGACGGCGACACGATCTCCCTCGGGGAGC
GGAGCAACATCCAAGACGGGGCGATCGTGCACGCAGACCCCGGATTCCCGGTGGCGGTCGCCCCGGACGTCTCGGTCGGG
CATGGCGCGGTCCTGCACGGATGCTTGGTCGAGGCCGGTTCCCTGGTCGGGATGCGGGCGGTGATCCTGAACGGTGCCAG
GATCGGTCCGATGTGCCTGGTCGCCGCCGGGTCCGTGGTGCTCGAGGGGACGGAGTTCGAAGCTCGCAGCCTCGTCGCAG
GAGTCCCCGCCAGGCGCCGGCGAGAGCTGACCGCCCAGGAGGTCCACGACCTGGCGCAGAATGCCACCGACTACCTGACC
CTGGCGGCTCGCTACCGGGACGCAGGTCCGCCGTGA

Upstream 100 bases:

>100_bases
ACGTCCACGAGTTCCTCTTCGTCGCCCTGCCCCTGAAGATCAAGGGCACCACCGGTTCGATGCTGGACCCGGTGGCCATC
ATCTGAAGGACAGGCACATC

Downstream 100 bases:

>100_bases
GCCGAGTCCGGCGAGTCATCGTGGCTCCAGACAAGTTCAAGGGCTCGTTGCGCGCCGCCGAGGTGGCGGATCTCATCGCC
GGCGCACTCGCGCAGCGTCC

Product: hexapaptide repeat-containing transferase

Products: cofactor [C]

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MRLRLEHHLPRVHPEAWVAPTAVLAGAVTVERGASVWFGSVIRADGDTISLGERSNIQDGAIVHADPGFPVAVAPDVSVG
HGAVLHGCLVEAGSLVGMRAVILNGARIGPMCLVAAGSVVLEGTEFEARSLVAGVPARRRRELTAQEVHDLAQNATDYLT
LAARYRDAGPP

Sequences:

>Translated_171_residues
MRLRLEHHLPRVHPEAWVAPTAVLAGAVTVERGASVWFGSVIRADGDTISLGERSNIQDGAIVHADPGFPVAVAPDVSVG
HGAVLHGCLVEAGSLVGMRAVILNGARIGPMCLVAAGSVVLEGTEFEARSLVAGVPARRRRELTAQEVHDLAQNATDYLT
LAARYRDAGPP
>Mature_171_residues
MRLRLEHHLPRVHPEAWVAPTAVLAGAVTVERGASVWFGSVIRADGDTISLGERSNIQDGAIVHADPGFPVAVAPDVSVG
HGAVLHGCLVEAGSLVGMRAVILNGARIGPMCLVAAGSVVLEGTEFEARSLVAGVPARRRRELTAQEVHDLAQNATDYLT
LAARYRDAGPP

Specific function: Carnitine metabolism (conversion of carnitine to gamma-butyrobetaine). [C]

COG id: COG0663

COG function: function code R; Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI87081681, Length=162, Percent_Identity=41.358024691358, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787667, Length=159, Percent_Identity=37.1069182389937, Blast_Score=104, Evalue=3e-24,
Organism=Escherichia coli, GI87082240, Length=168, Percent_Identity=31.547619047619, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 17921; Mature: 17921

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRLEHHLPRVHPEAWVAPTAVLAGAVTVERGASVWFGSVIRADGDTISLGERSNIQDG
CEECCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCEEECCEEECCCCEEECCCCCCCCCC
AIVHADPGFPVAVAPDVSVGHGAVLHGCLVEAGSLVGMRAVILNGARIGPMCLVAAGSVV
EEEECCCCCCEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHEECCCCCCCEEEEECCCEE
LEGTEFEARSLVAGVPARRRRELTAQEVHDLAQNATDYLTLAARYRDAGPP
EECCCCCHHHHHHCCCHHHHHHCCHHHHHHHHHCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRLRLEHHLPRVHPEAWVAPTAVLAGAVTVERGASVWFGSVIRADGDTISLGERSNIQDG
CEECCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCEEECCEEECCCCEEECCCCCCCCCC
AIVHADPGFPVAVAPDVSVGHGAVLHGCLVEAGSLVGMRAVILNGARIGPMCLVAAGSVV
EEEECCCCCCEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHEECCCCCCCEEEEECCCEE
LEGTEFEARSLVAGVPARRRRELTAQEVHDLAQNATDYLTLAARYRDAGPP
EECCCCCHHHHHHCCCHHHHHHCCHHHHHHHHHCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pre-cofactor [C]

Specific reaction: pre-cofactor = cofactor [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]