| Definition | Nocardioides sp. JS614 chromosome, complete genome. |
|---|---|
| Accession | NC_008699 |
| Length | 4,985,871 |
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The map label for this gene is echA12 [H]
Identifier: 119715049
GI number: 119715049
Start: 845636
End: 846433
Strand: Direct
Name: echA12 [H]
Synonym: Noca_0802
Alternate gene names: 119715049
Gene position: 845636-846433 (Clockwise)
Preceding gene: 119715048
Following gene: 119715050
Centisome position: 16.96
GC content: 68.8
Gene sequence:
>798_bases GTGGTTCTCGTCGAGGATCCGGCGCCTGGCGTCCGAACGATCACCTTGAACCGCCCGGAGCGGCTCAACGCCCTCTCGTA CGAGCTCTTCCAGGAGCTGGAGGAGGCCCTGCTCGCGTCGGATCGGGACCCCCGTGTACGGGTCGTCGTGGTCACCGGCG CCGGAAGGGCGTTCTGTGCTGGCCTCGATCTCGGCGACGGTTTCGACGCCCCGGAGCAGGCAGTCGCCGGTCGCACAGTG GGAGGGATGGACGCCCAAGAACGCATCGCGCGCGTGCTGACCACGCCGCAGCGGATGCGGACGCCGGTCATCGCAGCGAT CAACGGGCCGGCGGCAGGCGGCGGCCTCGCCCTCGCCCTTGCCTGCGACGTGCGGGTCGCGTCGGCCACGGCCAGCTGCA ATGTCGCCTTCGTGAAGGTGGGTCTGTCGGGATGTGACTGCGGGGTCAGCTACCTGCTGCCGCGGGCAGTCGGCAGCAGT GTTGCCTTCGAGCTGATGCTCACGGGTCGATCGGTGGACTCCGAGGAAGCGCTGAGAATCGGCCTGGTCTCCCGGATCAC CGCAGAGGAGCAACTGATCCCGGCGGCGCTCGAGACGGCGGCGCTGATCGTAAACAACAGCCCCTTCGGAGTGCAGATGA CCAAGCGGGTGATGTGGCAGGCCCTGGACGCTCCGAGCCTGGACGCGGCCATCGAGCTCGAGAACCGCACGCAGATCCTC TGCACCCTGACCGAGGATCAGCCCGAGGCGGTCGCTGCCTTCCGTGAGAAGCGGCCGCCTCGGTTCGGGCGCCGCTAA
Upstream 100 bases:
>100_bases ACCGCAGTCGGAGCAGCGGTGTCCGAGCTGGTCGAGCTCGTCGTGCGTCAGTGGGGGGCCGATCGTGTCTACTGAGTCTG CGATCACAGGTGCGGCACCG
Downstream 100 bases:
>100_bases GCGATGAGACGACGGAGGACGAAGACATGGATTTCACGATGACAGCGGCGGAACTGCGATTTCGTGACGAGTTGCGCGGG TGGCTCGCGGTGAACCCGCC
Product: enoyl-CoA hydratase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 265; Mature: 265
Protein sequence:
>265_residues MVLVEDPAPGVRTITLNRPERLNALSYELFQELEEALLASDRDPRVRVVVVTGAGRAFCAGLDLGDGFDAPEQAVAGRTV GGMDAQERIARVLTTPQRMRTPVIAAINGPAAGGGLALALACDVRVASATASCNVAFVKVGLSGCDCGVSYLLPRAVGSS VAFELMLTGRSVDSEEALRIGLVSRITAEEQLIPAALETAALIVNNSPFGVQMTKRVMWQALDAPSLDAAIELENRTQIL CTLTEDQPEAVAAFREKRPPRFGRR
Sequences:
>Translated_265_residues MVLVEDPAPGVRTITLNRPERLNALSYELFQELEEALLASDRDPRVRVVVVTGAGRAFCAGLDLGDGFDAPEQAVAGRTV GGMDAQERIARVLTTPQRMRTPVIAAINGPAAGGGLALALACDVRVASATASCNVAFVKVGLSGCDCGVSYLLPRAVGSS VAFELMLTGRSVDSEEALRIGLVSRITAEEQLIPAALETAALIVNNSPFGVQMTKRVMWQALDAPSLDAAIELENRTQIL CTLTEDQPEAVAAFREKRPPRFGRR >Mature_265_residues MVLVEDPAPGVRTITLNRPERLNALSYELFQELEEALLASDRDPRVRVVVVTGAGRAFCAGLDLGDGFDAPEQAVAGRTV GGMDAQERIARVLTTPQRMRTPVIAAINGPAAGGGLALALACDVRVASATASCNVAFVKVGLSGCDCGVSYLLPRAVGSS VAFELMLTGRSVDSEEALRIGLVSRITAEEQLIPAALETAALIVNNSPFGVQMTKRVMWQALDAPSLDAAIELENRTQIL CTLTEDQPEAVAAFREKRPPRFGRR
Specific function: Could possibly oxidize fatty acids using specific components [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=253, Percent_Identity=34.3873517786561, Blast_Score=120, Evalue=1e-27, Organism=Homo sapiens, GI70995211, Length=211, Percent_Identity=36.9668246445498, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI31542718, Length=255, Percent_Identity=29.4117647058824, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI4502327, Length=264, Percent_Identity=31.8181818181818, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI68989263, Length=165, Percent_Identity=36.3636363636364, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI260274832, Length=178, Percent_Identity=29.7752808988764, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI45643119, Length=178, Percent_Identity=29.7752808988764, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI260275230, Length=178, Percent_Identity=29.7752808988764, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI37594471, Length=189, Percent_Identity=29.6296296296296, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI37594469, Length=189, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4757966, Length=169, Percent_Identity=28.4023668639053, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI51538581, Length=169, Percent_Identity=28.4023668639053, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI25453481, Length=169, Percent_Identity=28.4023668639053, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI51538573, Length=169, Percent_Identity=28.4023668639053, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4757968, Length=169, Percent_Identity=28.4023668639053, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI49355787, Length=169, Percent_Identity=28.4023668639053, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI221136756, Length=164, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI221136753, Length=164, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI221307494, Length=164, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI116235487, Length=169, Percent_Identity=28.4023668639053, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI20127408, Length=181, Percent_Identity=31.4917127071823, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI157694516, Length=197, Percent_Identity=27.9187817258883, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI213417737, Length=197, Percent_Identity=27.9187817258883, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787660, Length=253, Percent_Identity=36.3636363636364, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI1787659, Length=255, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI221142681, Length=261, Percent_Identity=33.7164750957854, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1788597, Length=271, Percent_Identity=31.3653136531365, Blast_Score=101, Evalue=6e-23, Organism=Escherichia coli, GI87082183, Length=258, Percent_Identity=25.968992248062, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1788682, Length=197, Percent_Identity=31.9796954314721, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1790281, Length=190, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17536985, Length=254, Percent_Identity=33.0708661417323, Blast_Score=130, Evalue=9e-31, Organism=Caenorhabditis elegans, GI17534483, Length=274, Percent_Identity=33.2116788321168, Blast_Score=128, Evalue=2e-30, Organism=Caenorhabditis elegans, GI25145438, Length=256, Percent_Identity=35.9375, Blast_Score=126, Evalue=9e-30, Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=34.7826086956522, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17540306, Length=247, Percent_Identity=31.9838056680162, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17540714, Length=239, Percent_Identity=33.0543933054393, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17560910, Length=196, Percent_Identity=33.1632653061224, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17535521, Length=255, Percent_Identity=27.843137254902, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17549921, Length=216, Percent_Identity=28.2407407407407, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17558304, Length=168, Percent_Identity=32.7380952380952, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI20129971, Length=260, Percent_Identity=33.8461538461538, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI24653477, Length=260, Percent_Identity=33.8461538461538, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI19920382, Length=233, Percent_Identity=32.618025751073, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24653139, Length=260, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI19922422, Length=268, Percent_Identity=27.9850746268657, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24650670, Length=188, Percent_Identity=36.1702127659575, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI21357171, Length=210, Percent_Identity=30.952380952381, Blast_Score=84, Evalue=8e-17, Organism=Drosophila melanogaster, GI24654903, Length=178, Percent_Identity=30.3370786516854, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI19921000, Length=211, Percent_Identity=28.436018957346, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI24583077, Length=211, Percent_Identity=28.436018957346, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24583079, Length=211, Percent_Identity=28.436018957346, Blast_Score=67, Evalue=9e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.17 [H]
Molecular weight: Translated: 28144; Mature: 28144
Theoretical pI: Translated: 4.77; Mature: 4.77
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.3 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 2.3 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVLVEDPAPGVRTITLNRPERLNALSYELFQELEEALLASDRDPRVRVVVVTGAGRAFCA CEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEE GLDLGDGFDAPEQAVAGRTVGGMDAQERIARVLTTPQRMRTPVIAAINGPAAGGGLALAL ECCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCHHHHCCCEEEEECCCCCCCCEEEEE ACDVRVASATASCNVAFVKVGLSGCDCGVSYLLPRAVGSSVAFELMLTGRSVDSEEALRI EECEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHH GLVSRITAEEQLIPAALETAALIVNNSPFGVQMTKRVMWQALDAPSLDAAIELENRTQIL HHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEEE CTLTEDQPEAVAAFREKRPPRFGRR EEECCCCHHHHHHHHHCCCCCCCCC >Mature Secondary Structure MVLVEDPAPGVRTITLNRPERLNALSYELFQELEEALLASDRDPRVRVVVVTGAGRAFCA CEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEE GLDLGDGFDAPEQAVAGRTVGGMDAQERIARVLTTPQRMRTPVIAAINGPAAGGGLALAL ECCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCHHHHCCCEEEEECCCCCCCCEEEEE ACDVRVASATASCNVAFVKVGLSGCDCGVSYLLPRAVGSSVAFELMLTGRSVDSEEALRI EECEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHH GLVSRITAEEQLIPAALETAALIVNNSPFGVQMTKRVMWQALDAPSLDAAIELENRTQIL HHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEEE CTLTEDQPEAVAAFREKRPPRFGRR EEECCCCHHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]