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The map label for this gene is nuoI

Identifier: 119714792

GI number: 119714792

Start: 560060

End: 560650

Strand: Direct

Name: nuoI

Synonym: Noca_0528

Alternate gene names: 119714792

Gene position: 560060-560650 (Clockwise)

Preceding gene: 119714791

Following gene: 119714793

Centisome position: 11.23

GC content: 70.05

Gene sequence:

>591_bases
ATGGCTGGCAGTCCCGAGCCCAAGAGCATGCGCGAGCAGTTCTGGGACCCGATCGCCGGGTTCGGCGTCACCTTCCGGAC
CATGTTCAAGAAGGTCGTCACCGAGCAGTACCCGTTCGACAAGTACCCGACCGCTCCGCGCTTCCACGGTCGTCACCAGC
TCAACCGCTGGCCGGACGGCCTCGAGAAGTGCGTGGGCTGCGAGCTGTGCGCGTGGGCCTGCCCGGCCGACGCGATCTAC
GTCGAGGGCGCGTCCAACAGCGACGACCCGGACGGCGGGGAGCGGTTCAGCCCCGGCGAGCGCTACGGGCGCGTCTACCA
GATCAACTACCTGCGCTGCATCCTCTGTGGGCTGTGCATCGAGGCCTGCCCGACCCGGGCGCTGACGATGACCAACGAGT
ACGAGCTGGCCGACGACAACCGGGCCGACCTCATCTACGAGAAGTCCGACCTGCTGGCCCCGCTGCTGCCCGGCATGGAG
CAGCCGCCGCACCCGATGCGCCTCGGCGACGACGAGGGCGCCTACTACCGCGGCGAGTTCGCGGCGCCGGCGCCGACCGC
CCCCGGGTCGAGCACGGAGGCGGGAGCATGA

Upstream 100 bases:

>100_bases
GCGGGGCCGCGGTCCCGCTCACGTTCGACCGCAGTTCACCCATCGCCTCGTCGATGCCACAGCCCAGCGCTGCCACCCGC
AGCGCGGGGGAGGAGATCTG

Downstream 100 bases:

>100_bases
TCGCGTTCTGGATCCTCGCCCCCGTGATGGTGATCGCGGCGCTCGGCCTCCTCTTCGTCCGCAAGGCGGTGCACGCCGCG
CTGCTGCTGGCCGTCGTGAT

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I; NDH-1 subunit I

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MAGSPEPKSMREQFWDPIAGFGVTFRTMFKKVVTEQYPFDKYPTAPRFHGRHQLNRWPDGLEKCVGCELCAWACPADAIY
VEGASNSDDPDGGERFSPGERYGRVYQINYLRCILCGLCIEACPTRALTMTNEYELADDNRADLIYEKSDLLAPLLPGME
QPPHPMRLGDDEGAYYRGEFAAPAPTAPGSSTEAGA

Sequences:

>Translated_196_residues
MAGSPEPKSMREQFWDPIAGFGVTFRTMFKKVVTEQYPFDKYPTAPRFHGRHQLNRWPDGLEKCVGCELCAWACPADAIY
VEGASNSDDPDGGERFSPGERYGRVYQINYLRCILCGLCIEACPTRALTMTNEYELADDNRADLIYEKSDLLAPLLPGME
QPPHPMRLGDDEGAYYRGEFAAPAPTAPGSSTEAGA
>Mature_195_residues
AGSPEPKSMREQFWDPIAGFGVTFRTMFKKVVTEQYPFDKYPTAPRFHGRHQLNRWPDGLEKCVGCELCAWACPADAIYV
EGASNSDDPDGGERFSPGERYGRVYQINYLRCILCGLCIEACPTRALTMTNEYELADDNRADLIYEKSDLLAPLLPGMEQ
PPHPMRLGDDEGAYYRGEFAAPAPTAPGSSTEAGA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

Organism=Homo sapiens, GI4505371, Length=146, Percent_Identity=36.3013698630137, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1788617, Length=142, Percent_Identity=41.5492957746479, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1789075, Length=131, Percent_Identity=32.0610687022901, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555194, Length=139, Percent_Identity=38.8489208633094, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI17864306, Length=139, Percent_Identity=38.8489208633094, Blast_Score=111, Evalue=3e-25,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NUOI_NOCSJ (A1SE35)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_921757.1
- ProteinModelPortal:   A1SE35
- SMR:   A1SE35
- STRING:   A1SE35
- GeneID:   4596448
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_0528
- eggNOG:   COG1143
- HOGENOM:   HBG724359
- OMA:   NKAADAP
- PhylomeDB:   A1SE35
- ProtClustDB:   PRK05888
- BioCyc:   NSP35761:NOCA_0528-MONOMER
- HAMAP:   MF_01351
- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226
- Gene3D:   G3DSA:1.10.1060.10
- TIGRFAMs:   TIGR01971

Pfam domain/function: PF00037 Fer4

EC number: =1.6.99.5

Molecular weight: Translated: 21741; Mature: 21609

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSPEPKSMREQFWDPIAGFGVTFRTMFKKVVTEQYPFDKYPTAPRFHGRHQLNRWPDG
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCHHH
LEKCVGCELCAWACPADAIYVEGASNSDDPDGGERFSPGERYGRVYQINYLRCILCGLCI
HHHHHCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHCCCEEEEHHHHHHHHHHHH
EACPTRALTMTNEYELADDNRADLIYEKSDLLAPLLPGMEQPPHPMRLGDDEGAYYRGEF
HHCCCCEEEECCCEECCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCC
AAPAPTAPGSSTEAGA
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AGSPEPKSMREQFWDPIAGFGVTFRTMFKKVVTEQYPFDKYPTAPRFHGRHQLNRWPDG
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCHHH
LEKCVGCELCAWACPADAIYVEGASNSDDPDGGERFSPGERYGRVYQINYLRCILCGLCI
HHHHHCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHCCCEEEEHHHHHHHHHHHH
EACPTRALTMTNEYELADDNRADLIYEKSDLLAPLLPGMEQPPHPMRLGDDEGAYYRGEF
HHCCCCEEEECCCEECCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCC
AAPAPTAPGSSTEAGA
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA