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The map label for this gene is nadB [H]

Identifier: 119714726

GI number: 119714726

Start: 491481

End: 493208

Strand: Direct

Name: nadB [H]

Synonym: Noca_0462

Alternate gene names: 119714726

Gene position: 491481-493208 (Clockwise)

Preceding gene: 119714725

Following gene: 119714727

Centisome position: 9.86

GC content: 74.25

Gene sequence:

>1728_bases
GTGCAGCACCAGGGAGTGCCCGATCATGCAGTGCCCGACGAGGGAGTCCCGGACGTGCCCGCGGAGATCGACGCACCCGT
ACGCCGGGTCCCGGGCCGCCTGGTCGCACCCGAGCCCGGGTGGACCACCACCACCGACGTGGTCGTCGTCGGCTCGGGCA
TCGCGGGACTGACCGCCGCGCTCCGGCTGCGCGAGGAGGTCGGCACCGTTCTAGTGGTCACCAAGGACGTGCTGGCGGCC
GGCTCCACCCAATGGGCGCAGGGCGGCATCGCCGCCGCCCTCGGCCCCGGTGACACTCCCGCCGAGCACGAGCTCGACAC
CCTCGTCGCGGGCGCCGGCGCCTGCGACCGCGACGCCGTGCACGCGCTGGTCACCGAGGGACCCGAGGCGGTGCGCGAGC
TGATCGCGCTCGGCACGAACTTCGACCACGACCCGAATGGCGAGCTGTCCCTGACCCGCGAGGGTGGCCATCACCGCGAC
CGGATCGCGCACGCCGGCGGCGACGCCACCGGAGCCGAGATCCAGCGCGCCCTGATCGCCGCGATCGAGCAGGCCCCCGA
GATCGAGGTCATCCAGCACGCGCTGGCCGTCGACCTGCTCCTCGCCGAGGACGGCGGGGTCGCCGGCCTCACCCTGCACG
TGATGGGCGAGGGCCAGCGCGACGGCGTCGGCGCCGTGCACTGCCGGGCCGTGGTGCTCGCCAGCGGCGGGCTCGGCCAG
GTGTTCTCCCAGACCACCAACCCCGCGGTGTCGACCGGCGACGGCATGGCCGTCGCGCTGCGCGCCGGTGCGGTGCTCCG
CGACCTGGAGTTCGTGCAGTTCCACCCCACGGTCATGTACCTCGGCCCGGACTCGCTGGGCCAGCAGCCGCTGATCTCGG
AGGCCGTGCGCGGCGAGGGCGCGTTCCTGGTCGACTTCGAAGGCAACCGGTTCATGCAGGGCGTCCACGAGCTCGCCGAC
CTGGCCCCACGCGACGTCGTGGCCAAGGCGATCACCCGACGGATGAACGAGACCGGTCGACCGCACATGTGGCTGGACGC
CCGCCACCTCGGCGCCGACCTGTGGGAGCGGCGGTTCCCGACCATCCTCGCGACGACGCGTAGCCACGGGGTCGACCCGG
TCACCGAGCTGATCCCCGTCGCCCCGGCCTGCCACTACGCGTCGGGCGGCGTGCGCACCGACCTGTGGGGCCGCTCGTCG
GTGCCCGGGCTCTACGCCACGGGCGAGGTCGCGTGCTCCGGAGTGCACGGCGCCAACCGGCTCGCGTCCAACTCGCTGCT
CGAGGGCCTGGTGTTCTCGCGCCGGATCGCCCAGGTCCTGCCTGGCGAGCTCCGGCCGCTCGTGTGCCCGGCCGAGGACA
CCCGGACCGCCGGGCTGGTCCCGGGGGGTGCCCGGCGCGAGCTCCAGGACGTGATGACCGGCCGGGTCGGTGTGCTGCGC
AGCGCCGAAGGACTGGCCGACGCCACCGGTCTCCTGGACAAGCTGGCGGGGGAGCGCGCCGACGTGATCGACCAGGCTTC
GTGGGAGACCACCAACCTGCTCACGATCGCCGTGGCGCTCGCCGACGCCGCGGCGCTGCGCGAGGAGACCCGCGGCTCGC
ACTGGCGCGAGGACTTCCCCGACCGCGACGACGCCGGGTACGCCGGGCACTTCGACGTGGTGATGGCGGACGGCGCCAGC
ACCCTGCAGCTGGTCCCCGCACCTCCGACCGACCGGGACGACCGGTGA

Upstream 100 bases:

>100_bases
CGACAACCGGGTCGTGAGCACCGGCAGCGACCCGGCCGACGCCCCGGCCGGATCCGGACTGCTGCGCGGCGACCGCCCGG
CCGGACGCTAGCCTGCCCCT

Downstream 100 bases:

>100_bases
CCCCGGCGACGCCGTACGACGAGGAGCTCCGCGCCGCCGGCCTCGACCCGGAGGCGATCCGGGCCCAGGTCGCGCGGGCG
CTCGCGGAGGACCTGCCCGG

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO; Quinolinate synthase B [H]

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MQHQGVPDHAVPDEGVPDVPAEIDAPVRRVPGRLVAPEPGWTTTTDVVVVGSGIAGLTAALRLREEVGTVLVVTKDVLAA
GSTQWAQGGIAAALGPGDTPAEHELDTLVAGAGACDRDAVHALVTEGPEAVRELIALGTNFDHDPNGELSLTREGGHHRD
RIAHAGGDATGAEIQRALIAAIEQAPEIEVIQHALAVDLLLAEDGGVAGLTLHVMGEGQRDGVGAVHCRAVVLASGGLGQ
VFSQTTNPAVSTGDGMAVALRAGAVLRDLEFVQFHPTVMYLGPDSLGQQPLISEAVRGEGAFLVDFEGNRFMQGVHELAD
LAPRDVVAKAITRRMNETGRPHMWLDARHLGADLWERRFPTILATTRSHGVDPVTELIPVAPACHYASGGVRTDLWGRSS
VPGLYATGEVACSGVHGANRLASNSLLEGLVFSRRIAQVLPGELRPLVCPAEDTRTAGLVPGGARRELQDVMTGRVGVLR
SAEGLADATGLLDKLAGERADVIDQASWETTNLLTIAVALADAAALREETRGSHWREDFPDRDDAGYAGHFDVVMADGAS
TLQLVPAPPTDRDDR

Sequences:

>Translated_575_residues
MQHQGVPDHAVPDEGVPDVPAEIDAPVRRVPGRLVAPEPGWTTTTDVVVVGSGIAGLTAALRLREEVGTVLVVTKDVLAA
GSTQWAQGGIAAALGPGDTPAEHELDTLVAGAGACDRDAVHALVTEGPEAVRELIALGTNFDHDPNGELSLTREGGHHRD
RIAHAGGDATGAEIQRALIAAIEQAPEIEVIQHALAVDLLLAEDGGVAGLTLHVMGEGQRDGVGAVHCRAVVLASGGLGQ
VFSQTTNPAVSTGDGMAVALRAGAVLRDLEFVQFHPTVMYLGPDSLGQQPLISEAVRGEGAFLVDFEGNRFMQGVHELAD
LAPRDVVAKAITRRMNETGRPHMWLDARHLGADLWERRFPTILATTRSHGVDPVTELIPVAPACHYASGGVRTDLWGRSS
VPGLYATGEVACSGVHGANRLASNSLLEGLVFSRRIAQVLPGELRPLVCPAEDTRTAGLVPGGARRELQDVMTGRVGVLR
SAEGLADATGLLDKLAGERADVIDQASWETTNLLTIAVALADAAALREETRGSHWREDFPDRDDAGYAGHFDVVMADGAS
TLQLVPAPPTDRDDR
>Mature_575_residues
MQHQGVPDHAVPDEGVPDVPAEIDAPVRRVPGRLVAPEPGWTTTTDVVVVGSGIAGLTAALRLREEVGTVLVVTKDVLAA
GSTQWAQGGIAAALGPGDTPAEHELDTLVAGAGACDRDAVHALVTEGPEAVRELIALGTNFDHDPNGELSLTREGGHHRD
RIAHAGGDATGAEIQRALIAAIEQAPEIEVIQHALAVDLLLAEDGGVAGLTLHVMGEGQRDGVGAVHCRAVVLASGGLGQ
VFSQTTNPAVSTGDGMAVALRAGAVLRDLEFVQFHPTVMYLGPDSLGQQPLISEAVRGEGAFLVDFEGNRFMQGVHELAD
LAPRDVVAKAITRRMNETGRPHMWLDARHLGADLWERRFPTILATTRSHGVDPVTELIPVAPACHYASGGVRTDLWGRSS
VPGLYATGEVACSGVHGANRLASNSLLEGLVFSRRIAQVLPGELRPLVCPAEDTRTAGLVPGGARRELQDVMTGRVGVLR
SAEGLADATGLLDKLAGERADVIDQASWETTNLLTIAVALADAAALREETRGSHWREDFPDRDDAGYAGHFDVVMADGAS
TLQLVPAPPTDRDDR

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=530, Percent_Identity=32.6415094339623, Blast_Score=209, Evalue=6e-54,
Organism=Escherichia coli, GI1788928, Length=523, Percent_Identity=40.1529636711281, Blast_Score=328, Evalue=6e-91,
Organism=Escherichia coli, GI1786942, Length=564, Percent_Identity=35.1063829787234, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1790597, Length=561, Percent_Identity=32.7985739750446, Blast_Score=222, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI17550100, Length=526, Percent_Identity=34.0304182509506, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17505833, Length=527, Percent_Identity=32.8273244781784, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI71986328, Length=466, Percent_Identity=27.4678111587983, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322701, Length=562, Percent_Identity=33.9857651245552, Blast_Score=226, Evalue=6e-60,
Organism=Saccharomyces cerevisiae, GI6322416, Length=563, Percent_Identity=34.4582593250444, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6320788, Length=485, Percent_Identity=27.8350515463918, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322511, Length=481, Percent_Identity=27.2349272349272, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24663005, Length=556, Percent_Identity=33.8129496402878, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI17137288, Length=571, Percent_Identity=33.6252189141856, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24655642, Length=571, Percent_Identity=33.6252189141856, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24655647, Length=571, Percent_Identity=33.6252189141856, Blast_Score=206, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 60328; Mature: 60328

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHQGVPDHAVPDEGVPDVPAEIDAPVRRVPGRLVAPEPGWTTTTDVVVVGSGIAGLTAA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEECCCCCCCCCCCEEEEECCHHHHHHH
LRLREEVGTVLVVTKDVLAAGSTQWAQGGIAAALGPGDTPAEHELDTLVAGAGACDRDAV
HHHHHHHCEEEEEEHHHHHCCCCCHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHH
HALVTEGPEAVRELIALGTNFDHDPNGELSLTREGGHHRDRIAHAGGDATGAEIQRALIA
HHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHH
AIEQAPEIEVIQHALAVDLLLAEDGGVAGLTLHVMGEGQRDGVGAVHCRAVVLASGGLGQ
HHHCCCCHHHHHHHHHHEEEEECCCCEEEEEEEEEECCCCCCCCCEEEEEEEEECCCHHH
VFSQTTNPAVSTGDGMAVALRAGAVLRDLEFVQFHPTVMYLGPDSLGQQPLISEAVRGEG
HHHCCCCCCEECCCCEEEEEHHHHHHHHHHEEEECCEEEEECCCCCCCCHHHHHHHCCCC
AFLVDFEGNRFMQGVHELADLAPRDVVAKAITRRMNETGRPHMWLDARHLGADLWERRFP
CEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHCHHHHHHHCC
TILATTRSHGVDPVTELIPVAPACHYASGGVRTDLWGRSSVPGLYATGEVACSGVHGANR
EEEEECCCCCCCHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCEEECCCCEECCCCHHHH
LASNSLLEGLVFSRRIAQVLPGELRPLVCPAEDTRTAGLVPGGARRELQDVMTGRVGVLR
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHH
SAEGLADATGLLDKLAGERADVIDQASWETTNLLTIAVALADAAALREETRGSHWREDFP
CCCCHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCC
DRDDAGYAGHFDVVMADGASTLQLVPAPPTDRDDR
CCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MQHQGVPDHAVPDEGVPDVPAEIDAPVRRVPGRLVAPEPGWTTTTDVVVVGSGIAGLTAA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEECCCCCCCCCCCEEEEECCHHHHHHH
LRLREEVGTVLVVTKDVLAAGSTQWAQGGIAAALGPGDTPAEHELDTLVAGAGACDRDAV
HHHHHHHCEEEEEEHHHHHCCCCCHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHH
HALVTEGPEAVRELIALGTNFDHDPNGELSLTREGGHHRDRIAHAGGDATGAEIQRALIA
HHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHH
AIEQAPEIEVIQHALAVDLLLAEDGGVAGLTLHVMGEGQRDGVGAVHCRAVVLASGGLGQ
HHHCCCCHHHHHHHHHHEEEEECCCCEEEEEEEEEECCCCCCCCCEEEEEEEEECCCHHH
VFSQTTNPAVSTGDGMAVALRAGAVLRDLEFVQFHPTVMYLGPDSLGQQPLISEAVRGEG
HHHCCCCCCEECCCCEEEEEHHHHHHHHHHEEEECCEEEEECCCCCCCCHHHHHHHCCCC
AFLVDFEGNRFMQGVHELADLAPRDVVAKAITRRMNETGRPHMWLDARHLGADLWERRFP
CEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHCHHHHHHHCC
TILATTRSHGVDPVTELIPVAPACHYASGGVRTDLWGRSSVPGLYATGEVACSGVHGANR
EEEEECCCCCCCHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCEEECCCCEECCCCHHHH
LASNSLLEGLVFSRRIAQVLPGELRPLVCPAEDTRTAGLVPGGARRELQDVMTGRVGVLR
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHH
SAEGLADATGLLDKLAGERADVIDQASWETTNLLTIAVALADAAALREETRGSHWREDFP
CCCCHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCC
DRDDAGYAGHFDVVMADGASTLQLVPAPPTDRDDR
CCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]