Click here to switch to the map view.

The map label for this gene is cah [H]

Identifier: 119714625

GI number: 119714625

Start: 384577

End: 385362

Strand: Reverse

Name: cah [H]

Synonym: Noca_0359

Alternate gene names: 119714625

Gene position: 385362-384577 (Counterclockwise)

Preceding gene: 119714626

Following gene: 119714624

Centisome position: 7.73

GC content: 75.83

Gene sequence:

>786_bases
ATGAACGCCGCGCGCCCGAACCGACGCGTTCGGCTCCTGGTCGTCCTGTGCGTGGCGCTGGCCGCGGGCTCCTGTTCCGG
GGACGGCGACGGGACCCGCACCGAGCCCGGCGACCACGGCAGCGAGGCCGGCCGCGCCGAGCACTGGAGCTACGACGACG
TCGAGGCGTGGGAGGAGGCCTGCGCGACCGGGCGCGAGCAGTCACCGGTCGACCTCGCCGGTGCCACGAGCCGGGATCTC
CCCGACCTCGGGTTCGCCTACCGGCCGGCGCCGGCCACCGTGGTCGACAACGGCCACACGGTCCAGGCGAGCGTCGAGGG
GGCAGGCTCGCTCGAGCTCGACTGCGAGACGTTCGAGCTGCGCCAGCTCCACTTCCACAGCCCCAGCGAGCACCTGGTCG
CCGGCGCGTCGTACGCCGCCGAGGTCCACCTCGTCCACGAGGGCACCGACGGCCGGCTGGCCGTGGTCGCGGTGCTCGTC
CAGGAGGGCAGCGCCAACCCGGTGGTGGCGGCGCTGCTCGACCAGGTGCCGGCGGCGGGTGCCGAGCCCGTCGCCGCGGA
TGCTCCGGTCGACCCGGTGCGGGTGCTGCCGGCGGACCGGCGGGCATTCCGCTACGACGGCTCGCTGACGACGCCGCCGT
GCACCGAGGGCGTGGCCTGGTCCGTGCTCGCCGAGCCGATCACGTGGTCGGCGGGCCAGCTCGCGGAGTTCGCCGAGCGG
CACCCGGACTCGCACCGGCCGCCGCAGCCCCGGGACGGGCGGGTTCTGCTCCACGACGAACGCTGA

Upstream 100 bases:

>100_bases
CGGCCCGGCGGCCGAGGCGCCCGTGACCGACGGCTCCGACACCGAGATGCTGCTCATCGACTTCCGCTGACGGGAGGCGC
TCGGTCAGTAGCGTCCGCGC

Downstream 100 bases:

>100_bases
CACCATGTCGGCCATGACTCGCCCGTGGCGTCGCCGGCATCTCGGGACGGAGGCCGACCGGGCCACGTTCCGCACGCTGC
ACACGGCCTCGCTCGCCTCG

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MNAARPNRRVRLLVVLCVALAAGSCSGDGDGTRTEPGDHGSEAGRAEHWSYDDVEAWEEACATGREQSPVDLAGATSRDL
PDLGFAYRPAPATVVDNGHTVQASVEGAGSLELDCETFELRQLHFHSPSEHLVAGASYAAEVHLVHEGTDGRLAVVAVLV
QEGSANPVVAALLDQVPAAGAEPVAADAPVDPVRVLPADRRAFRYDGSLTTPPCTEGVAWSVLAEPITWSAGQLAEFAER
HPDSHRPPQPRDGRVLLHDER

Sequences:

>Translated_261_residues
MNAARPNRRVRLLVVLCVALAAGSCSGDGDGTRTEPGDHGSEAGRAEHWSYDDVEAWEEACATGREQSPVDLAGATSRDL
PDLGFAYRPAPATVVDNGHTVQASVEGAGSLELDCETFELRQLHFHSPSEHLVAGASYAAEVHLVHEGTDGRLAVVAVLV
QEGSANPVVAALLDQVPAAGAEPVAADAPVDPVRVLPADRRAFRYDGSLTTPPCTEGVAWSVLAEPITWSAGQLAEFAER
HPDSHRPPQPRDGRVLLHDER
>Mature_261_residues
MNAARPNRRVRLLVVLCVALAAGSCSGDGDGTRTEPGDHGSEAGRAEHWSYDDVEAWEEACATGREQSPVDLAGATSRDL
PDLGFAYRPAPATVVDNGHTVQASVEGAGSLELDCETFELRQLHFHSPSEHLVAGASYAAEVHLVHEGTDGRLAVVAVLV
QEGSANPVVAALLDQVPAAGAEPVAADAPVDPVRVLPADRRAFRYDGSLTTPPCTEGVAWSVLAEPITWSAGQLAEFAER
HPDSHRPPQPRDGRVLLHDER

Specific function: Reversible hydration of carbon dioxide [H]

COG id: COG3338

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-carbonic anhydrase family [H]

Homologues:

Organism=Homo sapiens, GI258679498, Length=253, Percent_Identity=30.8300395256917, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI192447434, Length=253, Percent_Identity=30.8300395256917, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI192447432, Length=253, Percent_Identity=30.8300395256917, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI192447430, Length=253, Percent_Identity=30.8300395256917, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI4502517, Length=253, Percent_Identity=30.8300395256917, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI38348436, Length=244, Percent_Identity=32.7868852459016, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4557395, Length=258, Percent_Identity=32.5581395348837, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI4885099, Length=260, Percent_Identity=32.6923076923077, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4885101, Length=256, Percent_Identity=32.03125, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI169636420, Length=248, Percent_Identity=33.8709677419355, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI62240989, Length=203, Percent_Identity=34.9753694581281, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI4502519, Length=239, Percent_Identity=29.2887029288703, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI45935383, Length=219, Percent_Identity=30.5936073059361, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4502521, Length=233, Percent_Identity=30.0429184549356, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4502515, Length=219, Percent_Identity=30.5936073059361, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI22027500, Length=244, Percent_Identity=29.5081967213115, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI6005723, Length=235, Percent_Identity=28.0851063829787, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI6912284, Length=257, Percent_Identity=28.0155642023346, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17568715, Length=246, Percent_Identity=36.1788617886179, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71995280, Length=270, Percent_Identity=29.6296296296296, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17569163, Length=159, Percent_Identity=37.1069182389937, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17569165, Length=159, Percent_Identity=37.1069182389937, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17737413, Length=265, Percent_Identity=31.3207547169811, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24645604, Length=260, Percent_Identity=27.6923076923077, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24651619, Length=249, Percent_Identity=25.7028112449799, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001148
- InterPro:   IPR018338
- InterPro:   IPR018340 [H]

Pfam domain/function: PF00194 Carb_anhydrase [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 27651; Mature: 27651

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00162 ALPHA_CA_1 ; PS51144 ALPHA_CA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAARPNRRVRLLVVLCVALAAGSCSGDGDGTRTEPGDHGSEAGRAEHWSYDDVEAWEEA
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
CATGREQSPVDLAGATSRDLPDLGFAYRPAPATVVDNGHTVQASVEGAGSLELDCETFEL
HHCCCCCCCCEECCCCCCCCCCCCCEECCCCCEEECCCCEEEEECCCCCCEEECCCCEEE
RQLHFHSPSEHLVAGASYAAEVHLVHEGTDGRLAVVAVLVQEGSANPVVAALLDQVPAAG
HEEECCCCHHHEEECCCCEEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCC
AEPVAADAPVDPVRVLPADRRAFRYDGSLTTPPCTEGVAWSVLAEPITWSAGQLAEFAER
CCCCCCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHH
HPDSHRPPQPRDGRVLLHDER
CCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MNAARPNRRVRLLVVLCVALAAGSCSGDGDGTRTEPGDHGSEAGRAEHWSYDDVEAWEEA
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
CATGREQSPVDLAGATSRDLPDLGFAYRPAPATVVDNGHTVQASVEGAGSLELDCETFEL
HHCCCCCCCCEECCCCCCCCCCCCCEECCCCCEEECCCCEEEEECCCCCCEEECCCCEEE
RQLHFHSPSEHLVAGASYAAEVHLVHEGTDGRLAVVAVLVQEGSANPVVAALLDQVPAAG
HEEECCCCHHHEEECCCCEEEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCC
AEPVAADAPVDPVRVLPADRRAFRYDGSLTTPPCTEGVAWSVLAEPITWSAGQLAEFAER
CCCCCCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHH
HPDSHRPPQPRDGRVLLHDER
CCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9811652 [H]