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The map label for this gene is actP [H]

Identifier: 119714621

GI number: 119714621

Start: 380814

End: 382331

Strand: Reverse

Name: actP [H]

Synonym: Noca_0355

Alternate gene names: 119714621

Gene position: 382331-380814 (Counterclockwise)

Preceding gene: 119714622

Following gene: 119714614

Centisome position: 7.67

GC content: 74.31

Gene sequence:

>1518_bases
GTGAGCACCGGGCTGGACGCCGCCCCTGGCATCGTCGCGGTGGCGGTGGTGACGATCGCGACGCTGGTCATCGGCACCTG
GGGGCTGCGGTTCTCCCGTACGACGAGCGACTTCTTCGTGGCCTCGCGCACGGTCCGGCCGCGGCTGAACGCGAGTGCGA
TCGGCGGCGAGTACCTCTCGGCCGCCTCCTTCCTCGGCGTCGCCGGGCTGGTGCTGACCTTCGGCGCCGACATGCTGTGG
TACCCCGTCGGCTGGACCGCCGGCTACCTCGTGCTGCTGGTGCTGGTCGCCGCGCCGCTGCGCCGCTCGGGTGCGTACAC
GCTGCCGGACTTCGCCGAGGCGCGGCTCGGGTCGCGCTCGGTGCGCGCGGTCTGCTCGCTGCTCGTCGTCGCCGTCGGCT
GGCTCTACCTGTTGCCGCAGTTCCAGGGCGCCGGCATCACGCTGCGCTCGACCCTCGGGGCCCCCACCTGGGTCGGGCCG
GTGATCGTCGGCCTGGTCGTGTTGGCGAACGTCACCTCGGGCGGGATGCGCAGCATCACGTTCGTCCAGGCCTTCCAGTA
CTGGCTCAAGCTCACCGCTCTCCTGGTCCCGGGGGCGGTGCTGCTGGTCGTCTGGGCCGGCGACTCCGCTCCGCTGCGGG
CGGGCTCCGACGGGTGGTCGGTGCCCCTGGCGGCGGGCGGCAACCAGGGCCTCTACGTGACCTACTCGCTGATCATCGCG
ACGTTCCTGGGCACCATGGGGCTGCCGCACGTGGTCGTCCGCTTCTACACCAACCCCGACGGTCGCGCGGCCCGCCGTAC
GACGCTCGTCGTGCTGGCGCTGCTCGGCGTGTTCTACCTGCTGCCGCCGCTGTACGGCGCCCTCGGGCGGGTCTACGCGC
CCTCGCTCGCCGAGTCCGGGCGCTCGGACGCGCTGGTGCTCGAGCTCCCCCGGATCATGCTCGACGGGCCGGCCGGGGAG
GTGCTCACCGGGCTGGTGACCGCGGGCGCGTTCGCCGCGTTCCTCTCCACGTCCTCCGGACTGTCGATCGCGGTGTCCGG
CGTGCTCAGCCAGGACGTGACCGGCCGCCCGTGGGCCGGCCGGCGGCTCGGCGGAGTCGCGGCGTTCCGGGTGGGGGCGG
TCGTCGCGGTCACCGTGCCGTGCGTGGTGGCGCTCGCGGCGCCGAACCTCGGCGTCGCCCGGGCGGTCGGGTTGGCCTTC
GCGATGGCCGCTTCGACGTTCTGCCCGCTGCTGCTGCTCGGGATCTGGTGGCGCCGGCTCACCCCCGCCGGTGCGTTGGC
GGGGCTGCTGGCCGGCGGCGTCGGCAGCGGCGTCGCCATCGCGTGGACGCTCGCCACGTCCCGTCCCTCGGGCTGGGCCG
ACGCGCTCATGGGCCAACCCGCCGCCTGGACCTTCCCCCTCGCGCTGACCACGATGGTCGTCGTGTCGCTGGCGACCGCC
CACCGGATCCCCACCCACGCCGGCCGGTTCCTGGTGCGCCTGCACACCCCCGAGACGCTCGGCCTGGACCGCAGCTGA

Upstream 100 bases:

>100_bases
TGCTCGCCTACCCGACGCTGCTGCTCCTCGGCTGGGTCTACGTCCGGCGGGCCGAGCGCAACGAGCGCGACTTCGCCGAG
CTGGTCTCGGAGGTGGAGGG

Downstream 100 bases:

>100_bases
CCCAGGTAGCGCGGGGCGGCCGGGCTCAGGAGGCGACGGCCAGCCGGTAGCCGCGCTTGACGACGGTCTGGACGGTGCGA
GTGCCGAGGGCCGCGCGCAG

Product: Na+/solute symporter

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MSTGLDAAPGIVAVAVVTIATLVIGTWGLRFSRTTSDFFVASRTVRPRLNASAIGGEYLSAASFLGVAGLVLTFGADMLW
YPVGWTAGYLVLLVLVAAPLRRSGAYTLPDFAEARLGSRSVRAVCSLLVVAVGWLYLLPQFQGAGITLRSTLGAPTWVGP
VIVGLVVLANVTSGGMRSITFVQAFQYWLKLTALLVPGAVLLVVWAGDSAPLRAGSDGWSVPLAAGGNQGLYVTYSLIIA
TFLGTMGLPHVVVRFYTNPDGRAARRTTLVVLALLGVFYLLPPLYGALGRVYAPSLAESGRSDALVLELPRIMLDGPAGE
VLTGLVTAGAFAAFLSTSSGLSIAVSGVLSQDVTGRPWAGRRLGGVAAFRVGAVVAVTVPCVVALAAPNLGVARAVGLAF
AMAASTFCPLLLLGIWWRRLTPAGALAGLLAGGVGSGVAIAWTLATSRPSGWADALMGQPAAWTFPLALTTMVVVSLATA
HRIPTHAGRFLVRLHTPETLGLDRS

Sequences:

>Translated_505_residues
MSTGLDAAPGIVAVAVVTIATLVIGTWGLRFSRTTSDFFVASRTVRPRLNASAIGGEYLSAASFLGVAGLVLTFGADMLW
YPVGWTAGYLVLLVLVAAPLRRSGAYTLPDFAEARLGSRSVRAVCSLLVVAVGWLYLLPQFQGAGITLRSTLGAPTWVGP
VIVGLVVLANVTSGGMRSITFVQAFQYWLKLTALLVPGAVLLVVWAGDSAPLRAGSDGWSVPLAAGGNQGLYVTYSLIIA
TFLGTMGLPHVVVRFYTNPDGRAARRTTLVVLALLGVFYLLPPLYGALGRVYAPSLAESGRSDALVLELPRIMLDGPAGE
VLTGLVTAGAFAAFLSTSSGLSIAVSGVLSQDVTGRPWAGRRLGGVAAFRVGAVVAVTVPCVVALAAPNLGVARAVGLAF
AMAASTFCPLLLLGIWWRRLTPAGALAGLLAGGVGSGVAIAWTLATSRPSGWADALMGQPAAWTFPLALTTMVVVSLATA
HRIPTHAGRFLVRLHTPETLGLDRS
>Mature_504_residues
STGLDAAPGIVAVAVVTIATLVIGTWGLRFSRTTSDFFVASRTVRPRLNASAIGGEYLSAASFLGVAGLVLTFGADMLWY
PVGWTAGYLVLLVLVAAPLRRSGAYTLPDFAEARLGSRSVRAVCSLLVVAVGWLYLLPQFQGAGITLRSTLGAPTWVGPV
IVGLVVLANVTSGGMRSITFVQAFQYWLKLTALLVPGAVLLVVWAGDSAPLRAGSDGWSVPLAAGGNQGLYVTYSLIIAT
FLGTMGLPHVVVRFYTNPDGRAARRTTLVVLALLGVFYLLPPLYGALGRVYAPSLAESGRSDALVLELPRIMLDGPAGEV
LTGLVTAGAFAAFLSTSSGLSIAVSGVLSQDVTGRPWAGRRLGGVAAFRVGAVVAVTVPCVVALAAPNLGVARAVGLAFA
MAASTFCPLLLLGIWWRRLTPAGALAGLLAGGVGSGVAIAWTLATSRPSGWADALMGQPAAWTFPLALTTMVVVSLATAH
RIPTHAGRFLVRLHTPETLGLDRS

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=487, Percent_Identity=23.8193018480493, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1790503, Length=440, Percent_Identity=31.1363636363636, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787251, Length=451, Percent_Identity=24.8337028824834, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87082237, Length=447, Percent_Identity=25.2796420581655, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 52230; Mature: 52099

Theoretical pI: Translated: 10.78; Mature: 10.78

Prosite motif: PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGLDAAPGIVAVAVVTIATLVIGTWGLRFSRTTSDFFVASRTVRPRLNASAIGGEYLS
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHCCCCCCCCCCCHHCCHHHHH
AASFLGVAGLVLTFGADMLWYPVGWTAGYLVLLVLVAAPLRRSGAYTLPDFAEARLGSRS
HHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHH
VRAVCSLLVVAVGWLYLLPQFQGAGITLRSTLGAPTWVGPVIVGLVVLANVTSGGMRSIT
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
FVQAFQYWLKLTALLVPGAVLLVVWAGDSAPLRAGSDGWSVPLAAGGNQGLYVTYSLIIA
HHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEHHHHHHHH
TFLGTMGLPHVVVRFYTNPDGRAARRTTLVVLALLGVFYLLPPLYGALGRVYAPSLAESG
HHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
RSDALVLELPRIMLDGPAGEVLTGLVTAGAFAAFLSTSSGLSIAVSGVLSQDVTGRPWAG
CCCEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCCC
RRLGGVAAFRVGAVVAVTVPCVVALAAPNLGVARAVGLAFAMAASTFCPLLLLGIWWRRL
CHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPAGALAGLLAGGVGSGVAIAWTLATSRPSGWADALMGQPAAWTFPLALTTMVVVSLATA
CHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHCCCCCCEEHHHHHHHHHHHHHHHH
HRIPTHAGRFLVRLHTPETLGLDRS
HCCCCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
STGLDAAPGIVAVAVVTIATLVIGTWGLRFSRTTSDFFVASRTVRPRLNASAIGGEYLS
CCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHCCCCCCCCCCCHHCCHHHHH
AASFLGVAGLVLTFGADMLWYPVGWTAGYLVLLVLVAAPLRRSGAYTLPDFAEARLGSRS
HHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHH
VRAVCSLLVVAVGWLYLLPQFQGAGITLRSTLGAPTWVGPVIVGLVVLANVTSGGMRSIT
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
FVQAFQYWLKLTALLVPGAVLLVVWAGDSAPLRAGSDGWSVPLAAGGNQGLYVTYSLIIA
HHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEHHHHHHHH
TFLGTMGLPHVVVRFYTNPDGRAARRTTLVVLALLGVFYLLPPLYGALGRVYAPSLAESG
HHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
RSDALVLELPRIMLDGPAGEVLTGLVTAGAFAAFLSTSSGLSIAVSGVLSQDVTGRPWAG
CCCEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCCC
RRLGGVAAFRVGAVVAVTVPCVVALAAPNLGVARAVGLAFAMAASTFCPLLLLGIWWRRL
CHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPAGALAGLLAGGVGSGVAIAWTLATSRPSGWADALMGQPAAWTFPLALTTMVVVSLATA
CHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHCCCCCCEEHHHHHHHHHHHHHHHH
HRIPTHAGRFLVRLHTPETLGLDRS
HCCCCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]