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The map label for this gene is caiD [C]

Identifier: 119714555

GI number: 119714555

Start: 306940

End: 307707

Strand: Direct

Name: caiD [C]

Synonym: Noca_0288

Alternate gene names: 119714555

Gene position: 306940-307707 (Clockwise)

Preceding gene: 119714554

Following gene: 119714558

Centisome position: 6.16

GC content: 77.34

Gene sequence:

>768_bases
GTGAGCGTCCGGGTCGAGGTCGACGGGCCGGTGACGACGGTCGTGCTCGACCGGCCCGAGACCCGCAACGCGGTCGACGG
CCCCACGGCTGCGGCGCTGGCCGCGGCGTTCCGGGCCTTCGACGAGGACGACACGCAGAGCGTGGCGGTGCTGCACGGCG
AGGGCGGCACCTTCTGCGCCGGCGCCGACCTCAAGTCGATCGGCACCGAGCGCGGCAACCAGGTCGCCGAGCCCATCGAC
GCCGCCGACGGGCCGATGGGTCCGACGCGGATGCGGCTGAGCAAGCCGGTGATCGCGGCGATCGAGGGGTACGCCGTCGC
GGGCGGGCTGGAGCTGGCGCTGTGGTGCGACCTGCGGGTCGCCGCGGACGACGCGGTCCTCGGGGTCTTCTGCCGGCGGT
GGGGCGTGCCCCTCGTCGACGGCGGCACGGTGCGGCTGCCCCGGCTGATCGGCACCAGCCGGGCGCTGGACCTGATCCTC
ACCGGTCGGGCTGTCGGCGCCGAGGAGGCCGAGCGGATCGGCCTGGTCAACCGGGTCGTCCCGGCCGGCCGGGCGCGCGC
GGAGGCCGAGGCGCTGGCGCGCTCGCTCGCCGTCCTCCCCCAGGAGTGCCTGCGGCAGGACCGGCTGTCCGTGCTCGACC
AGGAGGGCCGGACCGAGGCTGAGGCGCTCGCCGGCGAGCTGCGGCACGGGCTGGTCTCCCTGGCGGCCGACGCCCTCGGC
GGGGCCGCCCGGTTCGCCGCCGGCGAGGGGCGTCACGGCCGCTTCTGA

Upstream 100 bases:

>100_bases
GGGTCGAGCAGAACCCGCCGTACTACCGCGAGCTCGCGCAGCGGCACCTCGCCGGCGTCGCGGTGGTGGAGCCCGAGCCG
GTCGTGCGGGAGGTCGAGTC

Downstream 100 bases:

>100_bases
GTGACTCCCGGCGGGAGGTCCTCGAGGCACACCGCGACCAGCTCGGCAGCGCTGTCGCTGTCCTGGTGGACCTCCCAACC
GCGGTCGAAGGACACGAGCA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSVRVEVDGPVTTVVLDRPETRNAVDGPTAAALAAAFRAFDEDDTQSVAVLHGEGGTFCAGADLKSIGTERGNQVAEPID
AADGPMGPTRMRLSKPVIAAIEGYAVAGGLELALWCDLRVAADDAVLGVFCRRWGVPLVDGGTVRLPRLIGTSRALDLIL
TGRAVGAEEAERIGLVNRVVPAGRARAEAEALARSLAVLPQECLRQDRLSVLDQEGRTEAEALAGELRHGLVSLAADALG
GAARFAAGEGRHGRF

Sequences:

>Translated_255_residues
MSVRVEVDGPVTTVVLDRPETRNAVDGPTAAALAAAFRAFDEDDTQSVAVLHGEGGTFCAGADLKSIGTERGNQVAEPID
AADGPMGPTRMRLSKPVIAAIEGYAVAGGLELALWCDLRVAADDAVLGVFCRRWGVPLVDGGTVRLPRLIGTSRALDLIL
TGRAVGAEEAERIGLVNRVVPAGRARAEAEALARSLAVLPQECLRQDRLSVLDQEGRTEAEALAGELRHGLVSLAADALG
GAARFAAGEGRHGRF
>Mature_254_residues
SVRVEVDGPVTTVVLDRPETRNAVDGPTAAALAAAFRAFDEDDTQSVAVLHGEGGTFCAGADLKSIGTERGNQVAEPIDA
ADGPMGPTRMRLSKPVIAAIEGYAVAGGLELALWCDLRVAADDAVLGVFCRRWGVPLVDGGTVRLPRLIGTSRALDLILT
GRAVGAEEAERIGLVNRVVPAGRARAEAEALARSLAVLPQECLRQDRLSVLDQEGRTEAEALAGELRHGLVSLAADALGG
AARFAAGEGRHGRF

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=190, Percent_Identity=32.1052631578947, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI20127408, Length=178, Percent_Identity=30.3370786516854, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI31542718, Length=202, Percent_Identity=30.1980198019802, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI68989263, Length=140, Percent_Identity=39.2857142857143, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI70995211, Length=182, Percent_Identity=32.4175824175824, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4502327, Length=197, Percent_Identity=33.502538071066, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI221142681, Length=200, Percent_Identity=37.5, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787659, Length=194, Percent_Identity=36.0824742268041, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788682, Length=185, Percent_Identity=36.7567567567568, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790281, Length=189, Percent_Identity=32.2751322751323, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788597, Length=188, Percent_Identity=29.2553191489362, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787660, Length=198, Percent_Identity=33.8383838383838, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=243, Percent_Identity=49.3827160493827, Blast_Score=230, Evalue=6e-61,
Organism=Caenorhabditis elegans, GI17540714, Length=192, Percent_Identity=31.7708333333333, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=187, Percent_Identity=34.2245989304813, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17558304, Length=187, Percent_Identity=34.2245989304813, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17554946, Length=194, Percent_Identity=32.9896907216495, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25144276, Length=182, Percent_Identity=37.3626373626374, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17508951, Length=182, Percent_Identity=37.3626373626374, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=180, Percent_Identity=34.4444444444444, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17508953, Length=182, Percent_Identity=37.3626373626374, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=207, Percent_Identity=26.5700483091787, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=172, Percent_Identity=33.7209302325581, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25141363, Length=205, Percent_Identity=28.780487804878, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357171, Length=247, Percent_Identity=47.3684210526316, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24650670, Length=252, Percent_Identity=44.8412698412698, Blast_Score=194, Evalue=4e-50,
Organism=Drosophila melanogaster, GI20129971, Length=258, Percent_Identity=34.8837209302326, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24653477, Length=258, Percent_Identity=34.8837209302326, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24653139, Length=194, Percent_Identity=34.020618556701, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI19921000, Length=193, Percent_Identity=34.7150259067358, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583077, Length=193, Percent_Identity=34.7150259067358, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583079, Length=193, Percent_Identity=34.7150259067358, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19922422, Length=229, Percent_Identity=24.4541484716157, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 26549; Mature: 26418

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRVEVDGPVTTVVLDRPETRNAVDGPTAAALAAAFRAFDEDDTQSVAVLHGEGGTFCA
CEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEE
GADLKSIGTERGNQVAEPIDAADGPMGPTRMRLSKPVIAAIEGYAVAGGLELALWCDLRV
CCCHHHHCCCCCCHHHCCCCCCCCCCCCHHHHHCCCHHHHHCCEEEECCCEEEEEEEEEE
AADDAVLGVFCRRWGVPLVDGGTVRLPRLIGTSRALDLILTGRAVGAEEAERIGLVNRVV
CCCHHHHHHHHHHCCCCEECCCCEEEHHHHCCHHHEEEEEECCCCCHHHHHHHHHHHHHC
PAGRARAEAEALARSLAVLPQECLRQDRLSVLDQEGRTEAEALAGELRHGLVSLAADALG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GAARFAAGEGRHGRF
CHHHHCCCCCCCCCC
>Mature Secondary Structure 
SVRVEVDGPVTTVVLDRPETRNAVDGPTAAALAAAFRAFDEDDTQSVAVLHGEGGTFCA
EEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEE
GADLKSIGTERGNQVAEPIDAADGPMGPTRMRLSKPVIAAIEGYAVAGGLELALWCDLRV
CCCHHHHCCCCCCHHHCCCCCCCCCCCCHHHHHCCCHHHHHCCEEEECCCEEEEEEEEEE
AADDAVLGVFCRRWGVPLVDGGTVRLPRLIGTSRALDLILTGRAVGAEEAERIGLVNRVV
CCCHHHHHHHHHHCCCCEECCCCEEEHHHHCCHHHEEEEEECCCCCHHHHHHHHHHHHHC
PAGRARAEAEALARSLAVLPQECLRQDRLSVLDQEGRTEAEALAGELRHGLVSLAADALG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GAARFAAGEGRHGRF
CHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA