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The map label for this gene is recD [H]

Identifier: 119714520

GI number: 119714520

Start: 270200

End: 271954

Strand: Direct

Name: recD [H]

Synonym: Noca_0253

Alternate gene names: 119714520

Gene position: 270200-271954 (Clockwise)

Preceding gene: 119714519

Following gene: 119714521

Centisome position: 5.42

GC content: 74.7

Gene sequence:

>1755_bases
GTGACTGAGCTGTTCGAGCCCGTCGACGAGCACGACTGGCGGATCGCCACCGGCGCCACCGGGCTGCTCGCCACCTTCAA
CGCGGCCGGGGTGCTGACCTCCAGCGACGTGCACGTCGCCACCCGGATCGGTGTCCTCGGCGGCGAGACCGACGAGCGGA
TGCTGCTGGCGGTCGCGCTGACCGTGCGGGCCGTCCGCCGCGGCTCGGTCTGCCTCGACCTCGCCGGCGTGGCCGCGACC
GCCCCGGACCTGCCCTGGCCCGACGAGTGGCCGGTGGCCGGCTCGCCGCTCGTGCACGCCGGGGTGGTGCGCTGGGACCA
CGAGCTGCTCTACCTCGACCGCTACCACCGGCTCGAGCGGCAGGTCCACGACGACCTGGCCGCGCGCCTCGCGCTCGCAC
CGCCGGCGGTCGACGAGCAGCGGCTCGAAGCGGCGCTGGCGAGGCTCGGCGGCGGGCACTTCAGCGAGGAGCAGCGGGCG
GCCGTGGTCGCGGCCGTGCGCCGGCGTACCACCATCCTGACCGGCGGCCCCGGCACCGGGAAGACCACGACGGTGGCGCG
CCTGCTCGCGCTGCTCGCCGACCAGGCCGCCGGACGAGGGAGCAGGCTCTCGATCGCGCTGGCGGCGCCGACCGGCAAGG
CCGCGACCCGGCTGCAGGAGGCCGTGGTCACCGAGCTCGCGGCGGTCGCGACGGCCTGGCCGGAGGCGCCGGCCCTGGTC
GGACGACTCGACGGGCTGACCCTGCACCGGCTCCTCGGCTGGCGCCCGGACAACGCGACCCGGTTCCGCCACGATCGCGC
CAACCGGCTCAAGTACGACGTGGTCGTGGTCGACGAGTCCTCGATGGTCGAGCTGACGATGATGGGCCGGTTGCTGGAGG
CCCTGCGCCCGGACTCGCGACTGGTGCTGGTCGGCGACCCGCAGCAGCTCACCTCGGTCGGCGCGGGTGCGGTGCTGAGT
GACCTGGTGGCCGGCTACGAGGGCCGGCCGGACTCGCCGGTCGCGGCGTTGAGCACCAACTTCCGCTCCGAGGAGGACAT
CAAGTCCCTGGCAGCGGCGCTGCGCTCCGGCGACGCCGACGAGGTGATCGCGGTGCTGCGCGCGCCGTCGGAGCAGGTCT
CCTGGGTCGAGACCTCCGACGCGGCCGAGGTCGAGGCCGCGCTGCGCCCCGACTCGCTCGCGTCCGCCCGCGCGGTCTGG
GCCGCGGCGCGCGACGAGGACGCCGAGCGCGCGCTGGCCGAGCTGGACCGCTACCGGCTCCTGTGCGCGCACCGCGAGGG
GCTCTACGGCGTCCGCCGTTGGAACCACCTCGTCGAGCGCTGGCTCGCCGAGGACCCCGACGTGGAGATCTACGACGAGT
GGTACGTCGGCCGTCCGCTGCTGGTCACCAGCAACGACTACGCCCTCGACGTCTACAACGGGGAGAGCGGGGTCGTCGTG
CGGCAGGACCAGCGGCGGCGAGTGTTCGTGGCGGGGTCGGAACGGCTCAAGGAGTTCGCGCCCGGCCGTCTCGAGGCGGT
CGAGACGATGCACGCGATGACGATCCACAAGAGCCAGGGCAGCCAGGCCGACCGGGTGAGCGTGCTGCTCCCTGACGAGG
GGTCGCGGCTGCTCACCCTCGAGCTGTTCTACACGGCGATCACCCGGGCCCGGCACCACGTGCGCGTGGTCGGGTCGGAG
GCCGCCGTGCGCGCCGCCGTCGACACCCGGGCGCAGCGGGCCACCGGTCTGCGGGCGCGTCTCGCGGACGGTTGA

Upstream 100 bases:

>100_bases
GACACGCCATCGGTCGACGGCGCGCCCTGCGGTGTGTTCGCGTGGCGGCCACCGGTCGCCCTGGTCGAGGAGCTCTCCGA
CCTGCTGGACGGCGGTGCCC

Downstream 100 bases:

>100_bases
CGTAACCCCCGCGCAACGTGAGCGGGTTAGTGTCGGGGCGGATTGGAGTTGTGATGCCCTACCTGCTGCGCGTGGAGCTG
CCCGACGTCCCGGGATCGTT

Product: DNA helicase/exodeoxyribonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MTELFEPVDEHDWRIATGATGLLATFNAAGVLTSSDVHVATRIGVLGGETDERMLLAVALTVRAVRRGSVCLDLAGVAAT
APDLPWPDEWPVAGSPLVHAGVVRWDHELLYLDRYHRLERQVHDDLAARLALAPPAVDEQRLEAALARLGGGHFSEEQRA
AVVAAVRRRTTILTGGPGTGKTTTVARLLALLADQAAGRGSRLSIALAAPTGKAATRLQEAVVTELAAVATAWPEAPALV
GRLDGLTLHRLLGWRPDNATRFRHDRANRLKYDVVVVDESSMVELTMMGRLLEALRPDSRLVLVGDPQQLTSVGAGAVLS
DLVAGYEGRPDSPVAALSTNFRSEEDIKSLAAALRSGDADEVIAVLRAPSEQVSWVETSDAAEVEAALRPDSLASARAVW
AAARDEDAERALAELDRYRLLCAHREGLYGVRRWNHLVERWLAEDPDVEIYDEWYVGRPLLVTSNDYALDVYNGESGVVV
RQDQRRRVFVAGSERLKEFAPGRLEAVETMHAMTIHKSQGSQADRVSVLLPDEGSRLLTLELFYTAITRARHHVRVVGSE
AAVRAAVDTRAQRATGLRARLADG

Sequences:

>Translated_584_residues
MTELFEPVDEHDWRIATGATGLLATFNAAGVLTSSDVHVATRIGVLGGETDERMLLAVALTVRAVRRGSVCLDLAGVAAT
APDLPWPDEWPVAGSPLVHAGVVRWDHELLYLDRYHRLERQVHDDLAARLALAPPAVDEQRLEAALARLGGGHFSEEQRA
AVVAAVRRRTTILTGGPGTGKTTTVARLLALLADQAAGRGSRLSIALAAPTGKAATRLQEAVVTELAAVATAWPEAPALV
GRLDGLTLHRLLGWRPDNATRFRHDRANRLKYDVVVVDESSMVELTMMGRLLEALRPDSRLVLVGDPQQLTSVGAGAVLS
DLVAGYEGRPDSPVAALSTNFRSEEDIKSLAAALRSGDADEVIAVLRAPSEQVSWVETSDAAEVEAALRPDSLASARAVW
AAARDEDAERALAELDRYRLLCAHREGLYGVRRWNHLVERWLAEDPDVEIYDEWYVGRPLLVTSNDYALDVYNGESGVVV
RQDQRRRVFVAGSERLKEFAPGRLEAVETMHAMTIHKSQGSQADRVSVLLPDEGSRLLTLELFYTAITRARHHVRVVGSE
AAVRAAVDTRAQRATGLRARLADG
>Mature_583_residues
TELFEPVDEHDWRIATGATGLLATFNAAGVLTSSDVHVATRIGVLGGETDERMLLAVALTVRAVRRGSVCLDLAGVAATA
PDLPWPDEWPVAGSPLVHAGVVRWDHELLYLDRYHRLERQVHDDLAARLALAPPAVDEQRLEAALARLGGGHFSEEQRAA
VVAAVRRRTTILTGGPGTGKTTTVARLLALLADQAAGRGSRLSIALAAPTGKAATRLQEAVVTELAAVATAWPEAPALVG
RLDGLTLHRLLGWRPDNATRFRHDRANRLKYDVVVVDESSMVELTMMGRLLEALRPDSRLVLVGDPQQLTSVGAGAVLSD
LVAGYEGRPDSPVAALSTNFRSEEDIKSLAAALRSGDADEVIAVLRAPSEQVSWVETSDAAEVEAALRPDSLASARAVWA
AARDEDAERALAELDRYRLLCAHREGLYGVRRWNHLVERWLAEDPDVEIYDEWYVGRPLLVTSNDYALDVYNGESGVVVR
QDQRRRVFVAGSERLKEFAPGRLEAVETMHAMTIHKSQGSQADRVSVLLPDEGSRLLTLELFYTAITRARHHVRVVGSEA
AVRAAVDTRAQRATGLRARLADG

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=456, Percent_Identity=36.1842105263158, Blast_Score=214, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 63397; Mature: 63266

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELFEPVDEHDWRIATGATGLLATFNAAGVLTSSDVHVATRIGVLGGETDERMLLAVAL
CCCCCCCCCCCCEEEECCCCHHHHHHCCCCEEECCCCEEEEEEEECCCCCCHHHHHHHHH
TVRAVRRGSVCLDLAGVAATAPDLPWPDEWPVAGSPLVHAGVVRWDHELLYLDRYHRLER
HHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCEEEECCHHHHHHHHHHHHH
QVHDDLAARLALAPPAVDEQRLEAALARLGGGHFSEEQRAAVVAAVRRRTTILTGGPGTG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCEEEEECCCCCC
KTTTVARLLALLADQAAGRGSRLSIALAAPTGKAATRLQEAVVTELAAVATAWPEAPALV
CHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
GRLDGLTLHRLLGWRPDNATRFRHDRANRLKYDVVVVDESSMVELTMMGRLLEALRPDSR
HHCCCHHHHHHHCCCCCCCHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCE
LVLVGDPQQLTSVGAGAVLSDLVAGYEGRPDSPVAALSTNFRSEEDIKSLAAALRSGDAD
EEEEECHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCHH
EVIAVLRAPSEQVSWVETSDAAEVEAALRPDSLASARAVWAAARDEDAERALAELDRYRL
HHHHHHHCCCHHCCEEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LCAHREGLYGVRRWNHLVERWLAEDPDVEIYDEWYVGRPLLVTSNDYALDVYNGESGVVV
HHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECEECCCEEEEECCCEEEEEEECCCCEEE
RQDQRRRVFVAGSERLKEFAPGRLEAVETMHAMTIHKSQGSQADRVSVLLPDEGSRLLTL
ECCCCCEEEEECHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCEEEEH
ELFYTAITRARHHVRVVGSEAAVRAAVDTRAQRATGLRARLADG
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure 
TELFEPVDEHDWRIATGATGLLATFNAAGVLTSSDVHVATRIGVLGGETDERMLLAVAL
CCCCCCCCCCCEEEECCCCHHHHHHCCCCEEECCCCEEEEEEEECCCCCCHHHHHHHHH
TVRAVRRGSVCLDLAGVAATAPDLPWPDEWPVAGSPLVHAGVVRWDHELLYLDRYHRLER
HHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCEEEECCHHHHHHHHHHHHH
QVHDDLAARLALAPPAVDEQRLEAALARLGGGHFSEEQRAAVVAAVRRRTTILTGGPGTG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCEEEEECCCCCC
KTTTVARLLALLADQAAGRGSRLSIALAAPTGKAATRLQEAVVTELAAVATAWPEAPALV
CHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
GRLDGLTLHRLLGWRPDNATRFRHDRANRLKYDVVVVDESSMVELTMMGRLLEALRPDSR
HHCCCHHHHHHHCCCCCCCHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCE
LVLVGDPQQLTSVGAGAVLSDLVAGYEGRPDSPVAALSTNFRSEEDIKSLAAALRSGDAD
EEEEECHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCHH
EVIAVLRAPSEQVSWVETSDAAEVEAALRPDSLASARAVWAAARDEDAERALAELDRYRL
HHHHHHHCCCHHCCEEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LCAHREGLYGVRRWNHLVERWLAEDPDVEIYDEWYVGRPLLVTSNDYALDVYNGESGVVV
HHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECEECCCEEEEECCCEEEEEEECCCCEEE
RQDQRRRVFVAGSERLKEFAPGRLEAVETMHAMTIHKSQGSQADRVSVLLPDEGSRLLTL
ECCCCCEEEEECHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCEEEEH
ELFYTAITRARHHVRVVGSEAAVRAAVDTRAQRATGLRARLADG
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]