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The map label for this gene is phoR [H]

Identifier: 119714514

GI number: 119714514

Start: 259106

End: 260992

Strand: Reverse

Name: phoR [H]

Synonym: Noca_0247

Alternate gene names: 119714514

Gene position: 260992-259106 (Counterclockwise)

Preceding gene: 119714515

Following gene: 119714512

Centisome position: 5.23

GC content: 73.5

Gene sequence:

>1887_bases
TTGACCACCAGCCCGACGGCGGAGGGCATACTCGGGGAGCGGGCCCGGCGGGAGGCCGGCCCGCGGCTCGGCGGGAGGGC
GGAGACGGTGGTCGACACCGAGGTGGTGCACCACGAGGACGCACGGGCCGGGTGGTCGGACTCCGCCGCCCGGGCGGTGC
TCCAGCTGATGGTGGAGTCGGTCGCCGAGATGGTCGGCTTCGAGGTGGCGACGCTCTCGGTGGTGCTCGACGGCGACCTG
GTCACGATGGCCTACACCGGCCCCGAGGAGTTCCGCGACTACCTGATGGCCCCGGACCCGGTCACCGTCCTCGACCCGGT
GCTCGCCCGGGCGGAGAGCTGGGGCCGCTTCCACTTCCTCGCCGCCGAGGACTACGACGCCACCACCTTGGAGGGTCACT
GGATGGTGGTCGCCGACGGGCAGGTCGACGTGCCGGACGCCTGGCACCCGATGGACGTCCTGGTCGGGCTGCTCACCGAC
GACGACGGGCGGCTGGTCGGCGCGATGTCGGTGGACCGCCCGGTCTCCGGCCGGCGACCGGACCCGGCCCAACGGCGGCT
CCTGGAGCGGTACGCCGCGCAGGCCGAGCGCGCGGTGATGACGGCCTTCGAGCGGGAGGAGCTGGTGCAGCAGGTCGCGC
ACTCGGAGGCGGCGCGACGGCTGATCCGGTCCGCCTCGATGCCGGACCAAGCCTCGCTGCAGGCGGTGCTGGACCACACC
CACCGGCCGCTCGTGGAGGGCTTCGGCGCCGCTGGCTCGTGGCTCCAGGTCCTCGACCCGGACAGCGGCGGCGTCGGCTA
CGCCCGGACCCGCGAGGGTGAGGTGGTCTCCCTGTCCGACCGGATGATCGCCCTGGCGCACGGGCTGGCACCCCGGCTGT
GGGAGGCCCAGCAGGTGCTGGTCGTCGCCGAGGGTGTCGAACCGTCGCTGTCCGCGGAGTCCGGCGCCGGGCCACTTCTC
GAGGAGGCGCGCCGCCAGATCGCCGAGCTCGGCCTGACCTCCGCGATGGCCGTCCCGCTCGGCGCCGGCACCGAGTGCCT
CGGGTTCCTCGTGCTGTCCCGGCGCGCCCAGGACCCGCCCTGGTCGACCGTCGAGATCGGGTCGGCACTGCAGATCGGGT
ACGACCTCGGCGCCGCGCTGATGACCGTGCGCGCGCTCGAGCGCGAGCGCAGCCTGGTGCGCGAGCTGCAGCAGCTCGAC
GACTACCGGAGCCAGCTGATCGCCACGCTCTCCCACGAGCTGCGCACCCCGCTCACCGTCATCTCCGGCAACCTGGAGCT
GCTTGGCGACCTCTCCCTCGACGAGACCGCCCAGCACTACCAGGAGGCGATGACCCGGGGCACCACCCGGATGCAGAAGG
TCGTCGACGACCTGCTCCTCCTGGCGCGGGTGAGCGACCCGCAGCACCCGCTGGTACAGGTCCCGGTCGACCTGAACGCG
GTGACCCGCACGACCGTCGACCTGCTGACCGCACCGGCACTGGCCAAGGGCCTGTCCCTGCGCCTGCAGCACAATCCCCG
CGAGCACCTGGTGCCGGGCGATCCCGGCGAGCTCGACCGGTTGCTGACGAACCTGGTCAGCAACGCGGTCAAGTACACGC
CCGCCGGCGGCACCGTCACGGTCACGGTGGAGCGCCGTGGGGACGCCGCGGTGCTGGAGGTCGCCGACGACGGGCTGGGG
ATCTCCGAGGAGGACCAGGTCGGGCTGTTCCGCCCGTTCTTCCGCACGACGAACCCCGACGCGCTGCGCGAGCCGGGCAC
CGGGCTGGGCCTGGCGATCGTGGCCACCATCGTCGAGCGGCACGGAGGCGAGGTGCGGGTGCGCTCGCGCCTGGGTGTGG
GGACCACCTTCACGGTCACGTTCCCCGCAGCGGCGCCGGCCGGCTGA

Upstream 100 bases:

>100_bases
AGCAGGGCGAGGTCCACCACGCCCGCAACGCCGGAACCACCCCCATCGTCATCTACATCGCCACCCTGCTGCGCACCGGC
GCGCCGGCGGCCATCGCCGA

Downstream 100 bases:

>100_bases
CGCACAGGTAGCCCACAGCCGGTTCCGACGGCGGCGCAGGTCGCGGCCGTCCGCCGAGGTCATGGAACCCCAGATCCCCG
GCCCCACGCTCCCCTCGCAG

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MTTSPTAEGILGERARREAGPRLGGRAETVVDTEVVHHEDARAGWSDSAARAVLQLMVESVAEMVGFEVATLSVVLDGDL
VTMAYTGPEEFRDYLMAPDPVTVLDPVLARAESWGRFHFLAAEDYDATTLEGHWMVVADGQVDVPDAWHPMDVLVGLLTD
DDGRLVGAMSVDRPVSGRRPDPAQRRLLERYAAQAERAVMTAFEREELVQQVAHSEAARRLIRSASMPDQASLQAVLDHT
HRPLVEGFGAAGSWLQVLDPDSGGVGYARTREGEVVSLSDRMIALAHGLAPRLWEAQQVLVVAEGVEPSLSAESGAGPLL
EEARRQIAELGLTSAMAVPLGAGTECLGFLVLSRRAQDPPWSTVEIGSALQIGYDLGAALMTVRALERERSLVRELQQLD
DYRSQLIATLSHELRTPLTVISGNLELLGDLSLDETAQHYQEAMTRGTTRMQKVVDDLLLLARVSDPQHPLVQVPVDLNA
VTRTTVDLLTAPALAKGLSLRLQHNPREHLVPGDPGELDRLLTNLVSNAVKYTPAGGTVTVTVERRGDAAVLEVADDGLG
ISEEDQVGLFRPFFRTTNPDALREPGTGLGLAIVATIVERHGGEVRVRSRLGVGTTFTVTFPAAAPAG

Sequences:

>Translated_628_residues
MTTSPTAEGILGERARREAGPRLGGRAETVVDTEVVHHEDARAGWSDSAARAVLQLMVESVAEMVGFEVATLSVVLDGDL
VTMAYTGPEEFRDYLMAPDPVTVLDPVLARAESWGRFHFLAAEDYDATTLEGHWMVVADGQVDVPDAWHPMDVLVGLLTD
DDGRLVGAMSVDRPVSGRRPDPAQRRLLERYAAQAERAVMTAFEREELVQQVAHSEAARRLIRSASMPDQASLQAVLDHT
HRPLVEGFGAAGSWLQVLDPDSGGVGYARTREGEVVSLSDRMIALAHGLAPRLWEAQQVLVVAEGVEPSLSAESGAGPLL
EEARRQIAELGLTSAMAVPLGAGTECLGFLVLSRRAQDPPWSTVEIGSALQIGYDLGAALMTVRALERERSLVRELQQLD
DYRSQLIATLSHELRTPLTVISGNLELLGDLSLDETAQHYQEAMTRGTTRMQKVVDDLLLLARVSDPQHPLVQVPVDLNA
VTRTTVDLLTAPALAKGLSLRLQHNPREHLVPGDPGELDRLLTNLVSNAVKYTPAGGTVTVTVERRGDAAVLEVADDGLG
ISEEDQVGLFRPFFRTTNPDALREPGTGLGLAIVATIVERHGGEVRVRSRLGVGTTFTVTFPAAAPAG
>Mature_627_residues
TTSPTAEGILGERARREAGPRLGGRAETVVDTEVVHHEDARAGWSDSAARAVLQLMVESVAEMVGFEVATLSVVLDGDLV
TMAYTGPEEFRDYLMAPDPVTVLDPVLARAESWGRFHFLAAEDYDATTLEGHWMVVADGQVDVPDAWHPMDVLVGLLTDD
DGRLVGAMSVDRPVSGRRPDPAQRRLLERYAAQAERAVMTAFEREELVQQVAHSEAARRLIRSASMPDQASLQAVLDHTH
RPLVEGFGAAGSWLQVLDPDSGGVGYARTREGEVVSLSDRMIALAHGLAPRLWEAQQVLVVAEGVEPSLSAESGAGPLLE
EARRQIAELGLTSAMAVPLGAGTECLGFLVLSRRAQDPPWSTVEIGSALQIGYDLGAALMTVRALERERSLVRELQQLDD
YRSQLIATLSHELRTPLTVISGNLELLGDLSLDETAQHYQEAMTRGTTRMQKVVDDLLLLARVSDPQHPLVQVPVDLNAV
TRTTVDLLTAPALAKGLSLRLQHNPREHLVPGDPGELDRLLTNLVSNAVKYTPAGGTVTVTVERRGDAAVLEVADDGLGI
SEEDQVGLFRPFFRTTNPDALREPGTGLGLAIVATIVERHGGEVRVRSRLGVGTTFTVTFPAAAPAG

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=32.8767123287671, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=32.258064516129, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=34.0336134453782, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=30.3964757709251, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789149, Length=223, Percent_Identity=31.8385650224215, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI48994928, Length=228, Percent_Identity=32.0175438596491, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=31.9672131147541, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790346, Length=215, Percent_Identity=32.093023255814, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788549, Length=219, Percent_Identity=30.5936073059361, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=31.1688311688312, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786783, Length=235, Percent_Identity=31.4893617021277, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790861, Length=235, Percent_Identity=30.2127659574468, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787894, Length=221, Percent_Identity=33.0316742081448, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788279, Length=237, Percent_Identity=27.8481012658228, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081816, Length=240, Percent_Identity=27.0833333333333, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790300, Length=259, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789808, Length=262, Percent_Identity=29.0076335877863, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1790551, Length=224, Percent_Identity=31.6964285714286, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1789403, Length=200, Percent_Identity=32, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67658; Mature: 67527

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSPTAEGILGERARREAGPRLGGRAETVVDTEVVHHEDARAGWSDSAARAVLQLMVES
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
VAEMVGFEVATLSVVLDGDLVTMAYTGPEEFRDYLMAPDPVTVLDPVLARAESWGRFHFL
HHHHHCCEEEEEEEEECCCEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEE
AAEDYDATTLEGHWMVVADGQVDVPDAWHPMDVLVGLLTDDDGRLVGAMSVDRPVSGRRP
EECCCCCEEECCCEEEEECCEECCCCCCCHHHHHHHHEECCCCCEEEEEECCCCCCCCCC
DPAQRRLLERYAAQAERAVMTAFEREELVQQVAHSEAARRLIRSASMPDQASLQAVLDHT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
HRPLVEGFGAAGSWLQVLDPDSGGVGYARTREGEVVSLSDRMIALAHGLAPRLWEAQQVL
CCHHHHHCCCCCCEEEEECCCCCCCCCEECCCCCEEEECHHHHHHHHCCCHHHHCCCEEE
VVAEGVEPSLSAESGAGPLLEEARRQIAELGLTSAMAVPLGAGTECLGFLVLSRRAQDPP
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCCCCCC
WSTVEIGSALQIGYDLGAALMTVRALERERSLVRELQQLDDYRSQLIATLSHELRTPLTV
CCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ISGNLELLGDLSLDETAQHYQEAMTRGTTRMQKVVDDLLLLARVSDPQHPLVQVPVDLNA
EECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
VTRTTVDLLTAPALAKGLSLRLQHNPREHLVPGDPGELDRLLTNLVSNAVKYTPAGGTVT
HHHHHHHHHHHHHHHHCCEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHEEECCCCCEEE
VTVERRGDAAVLEVADDGLGISEEDQVGLFRPFFRTTNPDALREPGTGLGLAIVATIVER
EEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHH
HGGEVRVRSRLGVGTTFTVTFPAAAPAG
CCCCEEEEEECCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
TTSPTAEGILGERARREAGPRLGGRAETVVDTEVVHHEDARAGWSDSAARAVLQLMVES
CCCCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
VAEMVGFEVATLSVVLDGDLVTMAYTGPEEFRDYLMAPDPVTVLDPVLARAESWGRFHFL
HHHHHCCEEEEEEEEECCCEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEE
AAEDYDATTLEGHWMVVADGQVDVPDAWHPMDVLVGLLTDDDGRLVGAMSVDRPVSGRRP
EECCCCCEEECCCEEEEECCEECCCCCCCHHHHHHHHEECCCCCEEEEEECCCCCCCCCC
DPAQRRLLERYAAQAERAVMTAFEREELVQQVAHSEAARRLIRSASMPDQASLQAVLDHT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
HRPLVEGFGAAGSWLQVLDPDSGGVGYARTREGEVVSLSDRMIALAHGLAPRLWEAQQVL
CCHHHHHCCCCCCEEEEECCCCCCCCCEECCCCCEEEECHHHHHHHHCCCHHHHCCCEEE
VVAEGVEPSLSAESGAGPLLEEARRQIAELGLTSAMAVPLGAGTECLGFLVLSRRAQDPP
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCCCCCC
WSTVEIGSALQIGYDLGAALMTVRALERERSLVRELQQLDDYRSQLIATLSHELRTPLTV
CCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ISGNLELLGDLSLDETAQHYQEAMTRGTTRMQKVVDDLLLLARVSDPQHPLVQVPVDLNA
EECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
VTRTTVDLLTAPALAKGLSLRLQHNPREHLVPGDPGELDRLLTNLVSNAVKYTPAGGTVT
HHHHHHHHHHHHHHHHCCEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHEEECCCCCEEE
VTVERRGDAAVLEVADDGLGISEEDQVGLFRPFFRTTNPDALREPGTGLGLAIVATIVER
EEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHH
HGGEVRVRSRLGVGTTFTVTFPAAAPAG
CCCCEEEEEECCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]