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The map label for this gene is phoR [H]

Identifier: 119714461

GI number: 119714461

Start: 206511

End: 208160

Strand: Direct

Name: phoR [H]

Synonym: Noca_0194

Alternate gene names: 119714461

Gene position: 206511-208160 (Clockwise)

Preceding gene: 119714460

Following gene: 119714462

Centisome position: 4.14

GC content: 73.27

Gene sequence:

>1650_bases
ATGGACCAGAGCGAGCGCCTGCGCCGCGCGTTGCGTCCCTTCGCCTGGGTGGACGGCGATCCGGACCCGCGCGGCCTGCA
GGCGGGCTTCGTGCTGCTGGTGGTCCTGGACCGGCTGCTCCGTCGGGCCGCCGGCGTCCCCTCGGGCGACGGGAACTGGC
CGTTGCGCGGGGCGGCGCTGGCGCTCCTGATCCTGCTCGTGGTGATGGTCCTCCCGAGGTCGTGGCGTCGTACGCCGGTG
ATCGCGGCGCTCGCCGTCGCCGATCTCGGCGTCGTCGGCGTCAGCTCGCTCGGGCCGCAGGACGGCGGCACGTCCCTGCT
GGTGGTGTTGCCCGCCCTCTGGCTGGGCAACCGGCTGCGGATGCCCGGGGCGCTGATCACGGTGGCCGGATCCCTGCTGC
TGATCACCCTCCCGTCCCTGGCGGTCCACGGTCTCGAAGGCGAAGGGTTGTCCCGCGCGGTCCCGATGCCGATCGCCGCC
GGCCTGGTTGCGCTGGCGCTGGCCGCCGGTTTGGACCTGGCCGAGCTGGCCCGTCGTCGGGCCGAGGAGGGCGAGCAGCG
GTTGCAGCGGACCCTCGAGACCCTCGAGGCGGAACGCCAGACCTCCCAGGAGGTGTTCGACGGTGCCGACGTCGGCCTGA
TGCTCCTCGACGAGCGCGGTCGTCTGGTGGGCATGAACCGTCGCTACGAGGAGTTCATCAGGCTCTCCCTCCCCGACGAC
GACCTGCCCTGGCCGGGCAACACCTTCGCCGCCGACGGGACCACCCGGCTCACGGCGGACCAGCTGCCCAGTGCCCGGGC
GGCGCGCGGCGAGGAGTTCGAGGACTACCGGATGTGGTCCGGCGCCGACCCCGCGACCCGGCGGGCGGTCTCGGTGTCGG
GTCGCCGCTCCGTCAGCCCCGCCGGCAACGTCGTGGGGGCGGTGGTGGCGGCGACCGACATCACCGAGCTGATGCGGGCG
CTGGCCGTCAAGGAGGAGTTCGTCGCCACCGTCTCCCACGAGCTGCGCACGCCCCTGACCTCGATCGTCGGCTATGTCGC
CATCCTGCTCGAGGACGACACCCTGTCGGCCCAGGCGGTCGCGCAGCTGCGGGTGGTCGATCGCAACGCGGCGCGGCTCA
CCGCCCTGGTCGAGGCGCTCCTGCAGGAGGCACACCACGCGGACGGGCCCGTGCCCCTCGAGCGCGAGGAGGTCGACCTC
GCCCGGATCGCGAGAGCGAGCGTCGACGCCGCGGCCCCGACGGCCCTGGCGGAGGGCGTCGAGATCGAGTGCGACCTGCG
CGACCCCGTCCTGGTCGTGGCGGACCCGCAACTGCTCGCGCAGGTCGTCGACAACCTGGTGTCCAACGCGATCAAGTACA
CGCCGCGCGGCGGTCGGGCGCGCGTCAGCGCGCGCCGGGACGGCGAGCGCGTCGAGCTGACGGTCGCCGACAACGGCATC
GGCATCTCCGAGGCCGAGCGCGGCCAGCTGTTCACGAGGTTCTTCCGGACCCGGGCTGCCACCGAGTCCGCGATCCAGGG
AGTGGGGCTCGGGTTGAGCATCGCCAAGGCGATCGTGGAGAGCCACGGTGGTCAGATCGAGGTCGACAGCGAGGCGGGGC
GAGGCAGCGTCTTCCGGGTCTGGTTGCCGGTGGGCGACGTCCCCAGCTGA

Upstream 100 bases:

>100_bases
CGGCGCTCAAGTCGGATCGGACCCGGCCGATGGGACCCCCGTCACGAACGTGGATCGGGCGACGGCCGAGTTGGCGAGCA
GGCTGACAGGGGTGGATGCC

Downstream 100 bases:

>100_bases
GCTCAGGACCCTGCTGAACAATCCGCGCGGCTAACCGACGACCGGTGGAGCGTCGGCGGTGTCTGCCTCGGTCGAAGTGA
CGCTGCCACGCCTTCCCTCG

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MDQSERLRRALRPFAWVDGDPDPRGLQAGFVLLVVLDRLLRRAAGVPSGDGNWPLRGAALALLILLVVMVLPRSWRRTPV
IAALAVADLGVVGVSSLGPQDGGTSLLVVLPALWLGNRLRMPGALITVAGSLLLITLPSLAVHGLEGEGLSRAVPMPIAA
GLVALALAAGLDLAELARRRAEEGEQRLQRTLETLEAERQTSQEVFDGADVGLMLLDERGRLVGMNRRYEEFIRLSLPDD
DLPWPGNTFAADGTTRLTADQLPSARAARGEEFEDYRMWSGADPATRRAVSVSGRRSVSPAGNVVGAVVAATDITELMRA
LAVKEEFVATVSHELRTPLTSIVGYVAILLEDDTLSAQAVAQLRVVDRNAARLTALVEALLQEAHHADGPVPLEREEVDL
ARIARASVDAAAPTALAEGVEIECDLRDPVLVVADPQLLAQVVDNLVSNAIKYTPRGGRARVSARRDGERVELTVADNGI
GISEAERGQLFTRFFRTRAATESAIQGVGLGLSIAKAIVESHGGQIEVDSEAGRGSVFRVWLPVGDVPS

Sequences:

>Translated_549_residues
MDQSERLRRALRPFAWVDGDPDPRGLQAGFVLLVVLDRLLRRAAGVPSGDGNWPLRGAALALLILLVVMVLPRSWRRTPV
IAALAVADLGVVGVSSLGPQDGGTSLLVVLPALWLGNRLRMPGALITVAGSLLLITLPSLAVHGLEGEGLSRAVPMPIAA
GLVALALAAGLDLAELARRRAEEGEQRLQRTLETLEAERQTSQEVFDGADVGLMLLDERGRLVGMNRRYEEFIRLSLPDD
DLPWPGNTFAADGTTRLTADQLPSARAARGEEFEDYRMWSGADPATRRAVSVSGRRSVSPAGNVVGAVVAATDITELMRA
LAVKEEFVATVSHELRTPLTSIVGYVAILLEDDTLSAQAVAQLRVVDRNAARLTALVEALLQEAHHADGPVPLEREEVDL
ARIARASVDAAAPTALAEGVEIECDLRDPVLVVADPQLLAQVVDNLVSNAIKYTPRGGRARVSARRDGERVELTVADNGI
GISEAERGQLFTRFFRTRAATESAIQGVGLGLSIAKAIVESHGGQIEVDSEAGRGSVFRVWLPVGDVPS
>Mature_549_residues
MDQSERLRRALRPFAWVDGDPDPRGLQAGFVLLVVLDRLLRRAAGVPSGDGNWPLRGAALALLILLVVMVLPRSWRRTPV
IAALAVADLGVVGVSSLGPQDGGTSLLVVLPALWLGNRLRMPGALITVAGSLLLITLPSLAVHGLEGEGLSRAVPMPIAA
GLVALALAAGLDLAELARRRAEEGEQRLQRTLETLEAERQTSQEVFDGADVGLMLLDERGRLVGMNRRYEEFIRLSLPDD
DLPWPGNTFAADGTTRLTADQLPSARAARGEEFEDYRMWSGADPATRRAVSVSGRRSVSPAGNVVGAVVAATDITELMRA
LAVKEEFVATVSHELRTPLTSIVGYVAILLEDDTLSAQAVAQLRVVDRNAARLTALVEALLQEAHHADGPVPLEREEVDL
ARIARASVDAAAPTALAEGVEIECDLRDPVLVVADPQLLAQVVDNLVSNAIKYTPRGGRARVSARRDGERVELTVADNGI
GISEAERGQLFTRFFRTRAATESAIQGVGLGLSIAKAIVESHGGQIEVDSEAGRGSVFRVWLPVGDVPS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=267, Percent_Identity=28.0898876404494, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=33.9366515837104, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=30.5084745762712, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=31.4410480349345, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788393, Length=221, Percent_Identity=32.1266968325792, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=32.2869955156951, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI48994928, Length=274, Percent_Identity=29.9270072992701, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082128, Length=223, Percent_Identity=31.8385650224215, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=32.8947368421053, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788549, Length=269, Percent_Identity=28.2527881040892, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786783, Length=220, Percent_Identity=29.5454545454545, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=27.1551724137931, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=30.1652892561983, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789808, Length=271, Percent_Identity=30.2583025830258, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790861, Length=206, Percent_Identity=33.0097087378641, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788279, Length=262, Percent_Identity=26.7175572519084, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787894, Length=252, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58563; Mature: 58563

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQSERLRRALRPFAWVDGDPDPRGLQAGFVLLVVLDRLLRRAAGVPSGDGNWPLRGAAL
CCHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
ALLILLVVMVLPRSWRRTPVIAALAVADLGVVGVSSLGPQDGGTSLLVVLPALWLGNRLR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC
MPGALITVAGSLLLITLPSLAVHGLEGEGLSRAVPMPIAAGLVALALAAGLDLAELARRR
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
AEEGEQRLQRTLETLEAERQTSQEVFDGADVGLMLLDERGRLVGMNRRYEEFIRLSLPDD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCHHHHHHHEECCCCC
DLPWPGNTFAADGTTRLTADQLPSARAARGEEFEDYRMWSGADPATRRAVSVSGRRSVSP
CCCCCCCCCCCCCCCCCCHHHCCCCHHCCCCCCHHHHCCCCCCHHHHHEEECCCCCCCCC
AGNVVGAVVAATDITELMRALAVKEEFVATVSHELRTPLTSIVGYVAILLEDDTLSAQAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEECCCCCCHHHH
AQLRVVDRNAARLTALVEALLQEAHHADGPVPLEREEVDLARIARASVDAAAPTALAEGV
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHCCHHHHCCC
EIECDLRDPVLVVADPQLLAQVVDNLVSNAIKYTPRGGRARVSARRDGERVELTVADNGI
EEEECCCCCEEEEECHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCCEEEEEEECCCC
GISEAERGQLFTRFFRTRAATESAIQGVGLGLSIAKAIVESHGGQIEVDSEAGRGSVFRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEE
WLPVGDVPS
EECCCCCCC
>Mature Secondary Structure
MDQSERLRRALRPFAWVDGDPDPRGLQAGFVLLVVLDRLLRRAAGVPSGDGNWPLRGAAL
CCHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
ALLILLVVMVLPRSWRRTPVIAALAVADLGVVGVSSLGPQDGGTSLLVVLPALWLGNRLR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC
MPGALITVAGSLLLITLPSLAVHGLEGEGLSRAVPMPIAAGLVALALAAGLDLAELARRR
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
AEEGEQRLQRTLETLEAERQTSQEVFDGADVGLMLLDERGRLVGMNRRYEEFIRLSLPDD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCHHHHHHHEECCCCC
DLPWPGNTFAADGTTRLTADQLPSARAARGEEFEDYRMWSGADPATRRAVSVSGRRSVSP
CCCCCCCCCCCCCCCCCCHHHCCCCHHCCCCCCHHHHCCCCCCHHHHHEEECCCCCCCCC
AGNVVGAVVAATDITELMRALAVKEEFVATVSHELRTPLTSIVGYVAILLEDDTLSAQAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEECCCCCCHHHH
AQLRVVDRNAARLTALVEALLQEAHHADGPVPLEREEVDLARIARASVDAAAPTALAEGV
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHCCHHHHCCC
EIECDLRDPVLVVADPQLLAQVVDNLVSNAIKYTPRGGRARVSARRDGERVELTVADNGI
EEEECCCCCEEEEECHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCCEEEEEEECCCC
GISEAERGQLFTRFFRTRAATESAIQGVGLGLSIAKAIVESHGGQIEVDSEAGRGSVFRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEE
WLPVGDVPS
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]