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The map label for this gene is qor [H]

Identifier: 119714397

GI number: 119714397

Start: 142477

End: 143439

Strand: Direct

Name: qor [H]

Synonym: Noca_0130

Alternate gene names: 119714397

Gene position: 142477-143439 (Clockwise)

Preceding gene: 119714396

Following gene: 119714398

Centisome position: 2.86

GC content: 73.73

Gene sequence:

>963_bases
ATGCGCGCCGCCCAGGTCATCGACACCACCGGTCCCGCCGACGTCGTCGTCCGCGACGTCCCCGAGCCGACGCCCGGACC
CGACGACGTGCTGGTCGAGGTGCACCGGGTCGGCATCTCGTTCCCCGACCTGCTGCTGAGCAAGGGGGAGTACCAGCTCA
AGCCCGAGGTCCCGTTCACCCTCGGCGTCGACTTCGCCGGCACCGTGGTCAGCGGCGGGCCGTTCGAGCCCGGCCAGCGG
GTGGCCGGCGTGAACGGGTACGGCGGCGCCGCCGAGCTGGTCGTCAACCCGGCGCAGTTCACCTTCGCGCTGCCCGACCA
CGTCACCTTCGACGAGGGCGCGGCGCTGCCGATGAACTACCTCACCGCCCAGTTCGCGCTGGCCGAGCGCGGCGGCCTGC
GCGCGGGCGAGACCGTGCTCGTGCACGGCGCTGCCGGTGGCGTCGGGACCGCGAGCATCCAGGTCGCGAAGGGGTACGGC
GCGCGCACGATCGCCGTCGTCAGCACCGAGGAGAAGGCGGAGGTCGCCCGGGCGGCCGGGGCCGACGCCGCCGTACTGCT
CGAGGGCTTCAAGGACGCCGTCCTCCAGCTCACCGACGGCCGCGGCGTCGACGTGGTGGTCGACGTCGTCGGCGGCAGCG
CGTTCACCGACTCGCTGCGCTGCCTGGCCCCCCAGGGCCGGCTGCTGGTGGTCGGCTTCGCCGCCGGCCAGGGCATCCCG
GAGGTCCGGGTGAACCGGCTGCTGCTCAACAACGTCGACGTCCGCGGCGTGGGCTGGGGCGCGTACGCGATGACCCGGCC
CGGCTACCTGCAGGACCAGTGGGCGGCGCTGCTCCCGATGCTGGAGTCGGGCGTGGTCAAGCCGCCGATCGGCGCGACCT
ACGACCTCGACGAGGTGACTCGGGCCCTGGTGGACATGGACGAGCGCCGCACCCTCGGCAAGTCGGTCCTGCGCGTGCGG
TAA

Upstream 100 bases:

>100_bases
CGACCTGGACCCCGAGCTGCTCGGCTGGCTGCACGAGGCCTACGACCGGGCCTGAGACGGCACGACGGCCCACGAGCCCA
GGCGGCTAGCCTCGGGACCC

Downstream 100 bases:

>100_bases
GGGGTGACCCTCGGTCCTCGGCGCGCAGCAGGCCAGGGGATCGAGAGCCACGCCCTGGCCGGCGGACGACGCGGTGCCGT
GCGTCGCGGCCGCAGTCGAG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MRAAQVIDTTGPADVVVRDVPEPTPGPDDVLVEVHRVGISFPDLLLSKGEYQLKPEVPFTLGVDFAGTVVSGGPFEPGQR
VAGVNGYGGAAELVVNPAQFTFALPDHVTFDEGAALPMNYLTAQFALAERGGLRAGETVLVHGAAGGVGTASIQVAKGYG
ARTIAVVSTEEKAEVARAAGADAAVLLEGFKDAVLQLTDGRGVDVVVDVVGGSAFTDSLRCLAPQGRLLVVGFAAGQGIP
EVRVNRLLLNNVDVRGVGWGAYAMTRPGYLQDQWAALLPMLESGVVKPPIGATYDLDEVTRALVDMDERRTLGKSVLRVR

Sequences:

>Translated_320_residues
MRAAQVIDTTGPADVVVRDVPEPTPGPDDVLVEVHRVGISFPDLLLSKGEYQLKPEVPFTLGVDFAGTVVSGGPFEPGQR
VAGVNGYGGAAELVVNPAQFTFALPDHVTFDEGAALPMNYLTAQFALAERGGLRAGETVLVHGAAGGVGTASIQVAKGYG
ARTIAVVSTEEKAEVARAAGADAAVLLEGFKDAVLQLTDGRGVDVVVDVVGGSAFTDSLRCLAPQGRLLVVGFAAGQGIP
EVRVNRLLLNNVDVRGVGWGAYAMTRPGYLQDQWAALLPMLESGVVKPPIGATYDLDEVTRALVDMDERRTLGKSVLRVR
>Mature_320_residues
MRAAQVIDTTGPADVVVRDVPEPTPGPDDVLVEVHRVGISFPDLLLSKGEYQLKPEVPFTLGVDFAGTVVSGGPFEPGQR
VAGVNGYGGAAELVVNPAQFTFALPDHVTFDEGAALPMNYLTAQFALAERGGLRAGETVLVHGAAGGVGTASIQVAKGYG
ARTIAVVSTEEKAEVARAAGADAAVLLEGFKDAVLQLTDGRGVDVVVDVVGGSAFTDSLRCLAPQGRLLVVGFAAGQGIP
EVRVNRLLLNNVDVRGVGWGAYAMTRPGYLQDQWAALLPMLESGVVKPPIGATYDLDEVTRALVDMDERRTLGKSVLRVR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=310, Percent_Identity=31.2903225806452, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI13236495, Length=310, Percent_Identity=31.2903225806452, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI22538446, Length=339, Percent_Identity=28.9085545722714, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI22538444, Length=339, Percent_Identity=28.9085545722714, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI41872631, Length=313, Percent_Identity=31.3099041533546, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI18379349, Length=308, Percent_Identity=29.2207792207792, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI194239676, Length=308, Percent_Identity=29.2207792207792, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI24308257, Length=326, Percent_Identity=27.6073619631902, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI28557745, Length=327, Percent_Identity=31.1926605504587, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI47519420, Length=360, Percent_Identity=28.8888888888889, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI197927207, Length=172, Percent_Identity=30.2325581395349, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI156627571, Length=338, Percent_Identity=26.6272189349112, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI67078404, Length=288, Percent_Identity=24.6527777777778, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=314, Percent_Identity=30.8917197452229, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788073, Length=343, Percent_Identity=25.9475218658892, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790045, Length=341, Percent_Identity=24.9266862170088, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789651, Length=264, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI212642053, Length=315, Percent_Identity=29.2063492063492, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17507255, Length=327, Percent_Identity=27.217125382263, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17562876, Length=352, Percent_Identity=25, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=335, Percent_Identity=31.3432835820896, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI221330659, Length=304, Percent_Identity=27.6315789473684, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19920632, Length=304, Percent_Identity=27.6315789473684, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24581345, Length=324, Percent_Identity=25.6172839506173, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33413; Mature: 33413

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAQVIDTTGPADVVVRDVPEPTPGPDDVLVEVHRVGISFPDLLLSKGEYQLKPEVPFT
CCCCEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCEEECCCCCEE
LGVDFAGTVVSGGPFEPGQRVAGVNGYGGAAELVVNPAQFTFALPDHVTFDEGAALPMNY
ECCCCCCEEECCCCCCCCCEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCHHH
LTAQFALAERGGLRAGETVLVHGAAGGVGTASIQVAKGYGARTIAVVSTEEKAEVARAAG
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHCC
ADAAVLLEGFKDAVLQLTDGRGVDVVVDVVGGSAFTDSLRCLAPQGRLLVVGFAAGQGIP
CCHHHHHHHHHCEEEEECCCCCCEEEEEECCCCCHHCCHHEECCCCCEEEEEEECCCCCC
EVRVNRLLLNNVDVRGVGWGAYAMTRPGYLQDQWAALLPMLESGVVKPPIGATYDLDEVT
HHHHHHHEECCCCEEEECCCHHEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEECHHHHH
RALVDMDERRTLGKSVLRVR
HHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRAAQVIDTTGPADVVVRDVPEPTPGPDDVLVEVHRVGISFPDLLLSKGEYQLKPEVPFT
CCCCEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCEEECCCCCEE
LGVDFAGTVVSGGPFEPGQRVAGVNGYGGAAELVVNPAQFTFALPDHVTFDEGAALPMNY
ECCCCCCEEECCCCCCCCCEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCHHH
LTAQFALAERGGLRAGETVLVHGAAGGVGTASIQVAKGYGARTIAVVSTEEKAEVARAAG
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHCC
ADAAVLLEGFKDAVLQLTDGRGVDVVVDVVGGSAFTDSLRCLAPQGRLLVVGFAAGQGIP
CCHHHHHHHHHCEEEEECCCCCCEEEEEECCCCCHHCCHHEECCCCCEEEEEEECCCCCC
EVRVNRLLLNNVDVRGVGWGAYAMTRPGYLQDQWAALLPMLESGVVKPPIGATYDLDEVT
HHHHHHHEECCCCEEEECCCHHEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEECHHHHH
RALVDMDERRTLGKSVLRVR
HHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]