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The map label for this gene is hyuA [H]

Identifier: 119714362

GI number: 119714362

Start: 106207

End: 107760

Strand: Direct

Name: hyuA [H]

Synonym: Noca_0095

Alternate gene names: 119714362

Gene position: 106207-107760 (Clockwise)

Preceding gene: 119714361

Following gene: 119714363

Centisome position: 2.13

GC content: 72.2

Gene sequence:

>1554_bases
ATGCGCATCGGGATCGATGTGGGAGGCACCAACACCGATGCCGTCCTGATGGACGGTCACCAGGTGATGGGAGCGGTGAA
GTCGGCGACCCAGCCCGACGTCTCCTCGGGTATCAAGGCGACCCTCGAGAGCCTGCGGAAGCAGCGTCCGTTCGCGCCGG
AGGACATCCGGGCCGTGATGATCGGCACCACGCACTTCATCAACGCCCTCGTCGAGGCCCGGCACCTGGCCCCCACGGCG
GTGCTGCGGCTGGGGCTGCCCGCGACCAGCTCGCTGCCGCCGCTGGTCGACTGGCCGGAGCGGCTGGTGGAGGCCATCGG
CGGGCGGGCGTACCTGGCGCACGGCGGCCACGAGTTCGACGGGCGGCACATCGCGGAGCTCGACGAGGACGAGCTGCGCC
GGCACGTCCAGGACATGGTCGCGCACGGCCTCCGCTCGCTGGCGATCTCGTCGGTGTTCTCCCCGATCAACTCCGAGTTC
GAGCTGCGGGCCGCCGAGATCGTCGCCGAGGAGGCGGGGCCGGAGATGGCCGTCTCGATGTCCCACGAGATCGGCCGCGT
CGGGCTGCTCGAGCGCGAGAACGCCACGATCATCAACGCGGCCCTGCGCGAGCTCGCGCTGGGCATCGTGGACGGGCTCG
CCGGCACGCTCGCGAGCCTCGGCATCGACTCGCCGCTCTACCTCAGCCAGAACGACGGCACGCTGATGGACATGGACTTC
GCGCGCCGCTACCCGGTGGCGACCTTCGCGTCCGGGCCCACCAACTCCATGCGCGGCGCCGCCATCCTCTCCGGGCTCAA
GGACTGCGCCGTCGTCGACGTCGGTGGGACGACGAGCGACGTCGGGGTCCTGACCAACGGCTTCCCGCGCGAGGCGACCA
CCGAGGTCACCGTGGCGGGGGTGCGCACGAACTTCCGGATGCCGGACGTGCTGAGCATCGGCATCGGCGGCGGCAGCCTG
GTGCGCGGCAACGAGGCCGGCGTGACCGTGGGGCCCGACTCCGTGGGCTACCGCCTGACCCAGGAGGCCCTGGTCTTAGG
GGGCAGCACCCTCACGGCCACCGACATCGCCGTCGCGTCCGGCCGCGCCGACATCGGCGACCGCTCACTCGTGGCGCACC
TCGACCGCGCCACGATCGAGGCGGCGCTCGCCCGGATCGGCAGCGACGTCGCCGACGCGGTCGAGCGGATGCGCACCTCG
GCGGACGCCCTGCCCGTGGTCGCCGTCGGAGGCGGCTCGATCCTGCTTCCCGACCGGCTGGAGGGCTGCGGCGACGTCCA
CCGTCCCGAGCACTTCTCCGTCGCCAACGCGATCGGTGCCGCGATCGCCCAGGTCGGCGGCATGGTCGACCGGATCTACT
CGATCGCGCCCGGGCAGCGCGACGCGATCTGTGACGAGGCCCGGCAGGAGGCCAAGGACCGCGCCGTCGCGGCGGGCGCC
GACCCCGAGACGGTCTCGATCGCCGACTTCGACGAGGTCCCGATCCCCTACCTGCCCGGCAACGCCACCCGGATCCGCTG
CAAGGCGGTCGGTGACCTCTGGATGGAGCGATGA

Upstream 100 bases:

>100_bases
CTACATGCCGCCGCCGCCCAAGGACCGCCGCATGTGAGTCCGCCCCAGGCGGCACTCCCGATGTTCGGCTCGAGATCGTC
ATAGTTCGGAAAGGCAGCAC

Downstream 100 bases:

>100_bases
GCATGCGCGTGACCCCGACCGACCTGATCCCGATGGCCCGCGGCGCGGCCGTGCTGGGCGGCGGCGGCGGCGGTGACCCC
CACATCGGGCGGCTGCTCGC

Product: hydantoinase/oxoprolinase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MRIGIDVGGTNTDAVLMDGHQVMGAVKSATQPDVSSGIKATLESLRKQRPFAPEDIRAVMIGTTHFINALVEARHLAPTA
VLRLGLPATSSLPPLVDWPERLVEAIGGRAYLAHGGHEFDGRHIAELDEDELRRHVQDMVAHGLRSLAISSVFSPINSEF
ELRAAEIVAEEAGPEMAVSMSHEIGRVGLLERENATIINAALRELALGIVDGLAGTLASLGIDSPLYLSQNDGTLMDMDF
ARRYPVATFASGPTNSMRGAAILSGLKDCAVVDVGGTTSDVGVLTNGFPREATTEVTVAGVRTNFRMPDVLSIGIGGGSL
VRGNEAGVTVGPDSVGYRLTQEALVLGGSTLTATDIAVASGRADIGDRSLVAHLDRATIEAALARIGSDVADAVERMRTS
ADALPVVAVGGGSILLPDRLEGCGDVHRPEHFSVANAIGAAIAQVGGMVDRIYSIAPGQRDAICDEARQEAKDRAVAAGA
DPETVSIADFDEVPIPYLPGNATRIRCKAVGDLWMER

Sequences:

>Translated_517_residues
MRIGIDVGGTNTDAVLMDGHQVMGAVKSATQPDVSSGIKATLESLRKQRPFAPEDIRAVMIGTTHFINALVEARHLAPTA
VLRLGLPATSSLPPLVDWPERLVEAIGGRAYLAHGGHEFDGRHIAELDEDELRRHVQDMVAHGLRSLAISSVFSPINSEF
ELRAAEIVAEEAGPEMAVSMSHEIGRVGLLERENATIINAALRELALGIVDGLAGTLASLGIDSPLYLSQNDGTLMDMDF
ARRYPVATFASGPTNSMRGAAILSGLKDCAVVDVGGTTSDVGVLTNGFPREATTEVTVAGVRTNFRMPDVLSIGIGGGSL
VRGNEAGVTVGPDSVGYRLTQEALVLGGSTLTATDIAVASGRADIGDRSLVAHLDRATIEAALARIGSDVADAVERMRTS
ADALPVVAVGGGSILLPDRLEGCGDVHRPEHFSVANAIGAAIAQVGGMVDRIYSIAPGQRDAICDEARQEAKDRAVAAGA
DPETVSIADFDEVPIPYLPGNATRIRCKAVGDLWMER
>Mature_517_residues
MRIGIDVGGTNTDAVLMDGHQVMGAVKSATQPDVSSGIKATLESLRKQRPFAPEDIRAVMIGTTHFINALVEARHLAPTA
VLRLGLPATSSLPPLVDWPERLVEAIGGRAYLAHGGHEFDGRHIAELDEDELRRHVQDMVAHGLRSLAISSVFSPINSEF
ELRAAEIVAEEAGPEMAVSMSHEIGRVGLLERENATIINAALRELALGIVDGLAGTLASLGIDSPLYLSQNDGTLMDMDF
ARRYPVATFASGPTNSMRGAAILSGLKDCAVVDVGGTTSDVGVLTNGFPREATTEVTVAGVRTNFRMPDVLSIGIGGGSL
VRGNEAGVTVGPDSVGYRLTQEALVLGGSTLTATDIAVASGRADIGDRSLVAHLDRATIEAALARIGSDVADAVERMRTS
ADALPVVAVGGGSILLPDRLEGCGDVHRPEHFSVANAIGAAIAQVGGMVDRIYSIAPGQRDAICDEARQEAKDRAVAAGA
DPETVSIADFDEVPIPYLPGNATRIRCKAVGDLWMER

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 54163; Mature: 54163

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGIDVGGTNTDAVLMDGHQVMGAVKSATQPDVSSGIKATLESLRKQRPFAPEDIRAVM
CEEEEECCCCCCCEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
IGTTHFINALVEARHLAPTAVLRLGLPATSSLPPLVDWPERLVEAIGGRAYLAHGGHEFD
ECHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCC
GRHIAELDEDELRRHVQDMVAHGLRSLAISSVFSPINSEFELRAAEIVAEEAGPEMAVSM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEH
SHEIGRVGLLERENATIINAALRELALGIVDGLAGTLASLGIDSPLYLSQNDGTLMDMDF
HHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECHH
ARRYPVATFASGPTNSMRGAAILSGLKDCAVVDVGGTTSDVGVLTNGFPREATTEVTVAG
HHCCCCEEECCCCCCCCCHHHHHHCCCCCEEEECCCCCCCCHHHCCCCCCCCCCEEEEEE
VRTNFRMPDVLSIGIGGGSLVRGNEAGVTVGPDSVGYRLTQEALVLGGSTLTATDIAVAS
EEECCCCCCEEEEECCCCCEEECCCCCEEECCCCCCHHEEHHHHHCCCCCEEHHHEEEEC
GRADIGDRSLVAHLDRATIEAALARIGSDVADAVERMRTSADALPVVAVGGGSILLPDRL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCEECCHHH
EGCGDVHRPEHFSVANAIGAAIAQVGGMVDRIYSIAPGQRDAICDEARQEAKDRAVAAGA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEECCC
DPETVSIADFDEVPIPYLPGNATRIRCKAVGDLWMER
CCCEEEECCCCCCCCCCCCCCCCEEEEEEHHHHHCCC
>Mature Secondary Structure
MRIGIDVGGTNTDAVLMDGHQVMGAVKSATQPDVSSGIKATLESLRKQRPFAPEDIRAVM
CEEEEECCCCCCCEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
IGTTHFINALVEARHLAPTAVLRLGLPATSSLPPLVDWPERLVEAIGGRAYLAHGGHEFD
ECHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCC
GRHIAELDEDELRRHVQDMVAHGLRSLAISSVFSPINSEFELRAAEIVAEEAGPEMAVSM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEH
SHEIGRVGLLERENATIINAALRELALGIVDGLAGTLASLGIDSPLYLSQNDGTLMDMDF
HHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECHH
ARRYPVATFASGPTNSMRGAAILSGLKDCAVVDVGGTTSDVGVLTNGFPREATTEVTVAG
HHCCCCEEECCCCCCCCCHHHHHHCCCCCEEEECCCCCCCCHHHCCCCCCCCCCEEEEEE
VRTNFRMPDVLSIGIGGGSLVRGNEAGVTVGPDSVGYRLTQEALVLGGSTLTATDIAVAS
EEECCCCCCEEEEECCCCCEEECCCCCEEECCCCCCHHEEHHHHHCCCCCEEHHHEEEEC
GRADIGDRSLVAHLDRATIEAALARIGSDVADAVERMRTSADALPVVAVGGGSILLPDRL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCEECCHHH
EGCGDVHRPEHFSVANAIGAAIAQVGGMVDRIYSIAPGQRDAICDEARQEAKDRAVAAGA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEECCC
DPETVSIADFDEVPIPYLPGNATRIRCKAVGDLWMER
CCCEEEECCCCCCCCCCCCCCCCEEEEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]