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The map label for this gene is rhtB [C]

Identifier: 119714338

GI number: 119714338

Start: 79607

End: 80230

Strand: Reverse

Name: rhtB [C]

Synonym: Noca_0070

Alternate gene names: 119714338

Gene position: 80230-79607 (Counterclockwise)

Preceding gene: 119714340

Following gene: 119714337

Centisome position: 1.61

GC content: 70.51

Gene sequence:

>624_bases
ATGGACACGTCGGCGCTGGTCGCGTTTACGGTCGTCGCGGCTGCCATGGTGGTGCTGCCGGGACCGGACTGGGCGCTCGT
TCTGGCAGCCGGGTCGCGTCGGAGCGGGGCGGTGATGGTCCCCACCATCTTTGGACTTGCCCTGGGGTACGCGTTGCTCA
CCGGCGTGGTGGCCACCGGTCTAGGACCCCTGATCGCTGCGGCGCCGGTGGCCTTGGTGGTGTTGACCGTGGTGGGTGCC
GCCTATCTGATCTACCTCGGGGTCGGCATCCTCTGCGGCCCTGCGACGGGGGTGCCGGAGGCCCGTGCGGTGGCGCCGGT
GAGCCGGCTGGGCTCTGTATTGCGCGGGGTGGGGGTCAGCGCTTTGAACCCCAAGGCTCTGTTGTTCTTCTTGGCCTTTC
TTCCGCAGTTCGCGCGTCCGGCGGCGCCCTGGCCCCTGGCCGGGCAACTGTTCGTGCTCGGCGGCGTCTGGGTCGTTCTG
ATCGTGGCGTTCTACACGGTCCTGGGCCACGCCGCCCGCACGCTTTCGGGCAGCCCCGGCCGCGCGAGGGCCGTGACCTG
GCTGGCGGGCGCCGTGATGATCCTCGTCGGCCTGGGCCTGCTGGTCGAACAGCTCGCGTGGTGA

Upstream 100 bases:

>100_bases
TCCTATGCCGGGCCTTGTGACGTATCGTGCCCTCCTCCGATGGCGGGAGGGTCCGGCCGGCGCGGCCGGACCGGTCAGGG
ACGGTGACCGAGAGGTTGGG

Downstream 100 bases:

>100_bases
GCGCCCCCGGCCGGCTCCTCGTTCTCAGATTTCTCAGCGTCTTAAGGAGGGCGTGGTGTTCGACATCCACTGCAACGCCT
GCGGCAAGCATCAGCTGCTG

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MDTSALVAFTVVAAAMVVLPGPDWALVLAAGSRRSGAVMVPTIFGLALGYALLTGVVATGLGPLIAAAPVALVVLTVVGA
AYLIYLGVGILCGPATGVPEARAVAPVSRLGSVLRGVGVSALNPKALLFFLAFLPQFARPAAPWPLAGQLFVLGGVWVVL
IVAFYTVLGHAARTLSGSPGRARAVTWLAGAVMILVGLGLLVEQLAW

Sequences:

>Translated_207_residues
MDTSALVAFTVVAAAMVVLPGPDWALVLAAGSRRSGAVMVPTIFGLALGYALLTGVVATGLGPLIAAAPVALVVLTVVGA
AYLIYLGVGILCGPATGVPEARAVAPVSRLGSVLRGVGVSALNPKALLFFLAFLPQFARPAAPWPLAGQLFVLGGVWVVL
IVAFYTVLGHAARTLSGSPGRARAVTWLAGAVMILVGLGLLVEQLAW
>Mature_207_residues
MDTSALVAFTVVAAAMVVLPGPDWALVLAAGSRRSGAVMVPTIFGLALGYALLTGVVATGLGPLIAAAPVALVVLTVVGA
AYLIYLGVGILCGPATGVPEARAVAPVSRLGSVLRGVGVSALNPKALLFFLAFLPQFARPAAPWPLAGQLFVLGGVWVVL
IVAFYTVLGHAARTLSGSPGRARAVTWLAGAVMILVGLGLLVEQLAW

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=163, Percent_Identity=33.7423312883436, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 20887; Mature: 20887

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSALVAFTVVAAAMVVLPGPDWALVLAAGSRRSGAVMVPTIFGLALGYALLTGVVATG
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
LGPLIAAAPVALVVLTVVGAAYLIYLGVGILCGPATGVPEARAVAPVSRLGSVLRGVGVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
ALNPKALLFFLAFLPQFARPAAPWPLAGQLFVLGGVWVVLIVAFYTVLGHAARTLSGSPG
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RARAVTWLAGAVMILVGLGLLVEQLAW
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTSALVAFTVVAAAMVVLPGPDWALVLAAGSRRSGAVMVPTIFGLALGYALLTGVVATG
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
LGPLIAAAPVALVVLTVVGAAYLIYLGVGILCGPATGVPEARAVAPVSRLGSVLRGVGVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
ALNPKALLFFLAFLPQFARPAAPWPLAGQLFVLGGVWVVLIVAFYTVLGHAARTLSGSPG
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RARAVTWLAGAVMILVGLGLLVEQLAW
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8169201; 10984043 [H]