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The map label for this gene is gbpR [H]

Identifier: 119386953

GI number: 119386953

Start: 1414230

End: 1415183

Strand: Direct

Name: gbpR [H]

Synonym: Pden_4248

Alternate gene names: 119386953

Gene position: 1414230-1415183 (Clockwise)

Preceding gene: 119386949

Following gene: 119386955

Centisome position: 81.74

GC content: 68.45

Gene sequence:

>954_bases
ATGCCATTCCCGCCCGCCCGCCTGATGCTGAAACCCGCCCAATTGCGGCTGATCCAGCAGATCGCCGAAACCGGCCAGCT
GCAACTGGCGGCCGAGCGGATCGGCATGACCCAGCCCGCCGCCTCGCGCATGCTGGCCGAGATCGAGAACCAGATCGGCG
CGCAACTGTTCCTGCGCCAGCCCAAGGGCATGGAGCCGACCGAGATCGGCCGCACCGTGCTGCGCCGCGCCCGCGTCATC
CTGCGCGAGATGTCCAGCATGGCCTCGGACGTGCAGGCGCTGCGCGAGGGGTTCGGCGGCGCGCTGCGCGTGGGCGCGGT
GACCGGGCCGGCGGTCAGCTACCTCGTCTCGGCCATCCGCGAGATCAAGCAGGGCGCGCCCGAGGCCGACATCACCGTCG
ATGTCATGCCTTCGCGCGAATTGCTGCTGCACCTGGCGGCCGAAGAGATGGATTTCGTGCTGGCCCGCATCTTGCCGGAA
TTCGACAGCCGGGATTTCAACATCCTGCCGATGCGGGACGAGAAGGTGGCCTTCCTGGTGCGGGCCAGCCATCCGCTGAG
CCGCTCGCCCTCGGTCACGCTGACCGAGCTTGCCGGCCAGGAATGGATCATGCAGCAACGCGGCGCCCCGATCCGCGAGG
CGGCGCTGGCGGCCTTTGCCGATGTCGGGCTGTCCGAGCCGAGAAACATCGTCAACAGCCCCTCGCTGCTTCTGACCATC
GCCTATCTGGCGCAGGGCGATGCCGTGGCGCCGATGTCCGAGGAGGTGGCGGAACTGCTGATCCGGCCGCCGGTCGGGGC
GGGTTTCGCCGTGCTGCAAGTGCCGCATGAGATCCGCGTCTCGCCCTATTACCTGCTGGACCTGAAGCGCCGGCCCTTGT
CGCCCTTGGCGATGCGACTTCGCGAGAAGCTGGTGGCACTGTCGCAAAGCCCGGTGCGGGACGCATTCGGCTGA

Upstream 100 bases:

>100_bases
GGCCGCATCCCCGTCCCCTCCTGACGGTCGGGCTTGATCTAGCCATGAAAGGACATGATGGTAAAATTACATCGCTTGCA
ATTTGCATATCGGAATCGTC

Downstream 100 bases:

>100_bases
GGCGGCGACAGGGCGCGCCGCCGCATGAGTATTTGGGGAACGAAGAAGCCGGCGCCGCGCGGGACGGGCGGCGCCGGGCG
CGTCGTCAGGCGTTTTGCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MPFPPARLMLKPAQLRLIQQIAETGQLQLAAERIGMTQPAASRMLAEIENQIGAQLFLRQPKGMEPTEIGRTVLRRARVI
LREMSSMASDVQALREGFGGALRVGAVTGPAVSYLVSAIREIKQGAPEADITVDVMPSRELLLHLAAEEMDFVLARILPE
FDSRDFNILPMRDEKVAFLVRASHPLSRSPSVTLTELAGQEWIMQQRGAPIREAALAAFADVGLSEPRNIVNSPSLLLTI
AYLAQGDAVAPMSEEVAELLIRPPVGAGFAVLQVPHEIRVSPYYLLDLKRRPLSPLAMRLREKLVALSQSPVRDAFG

Sequences:

>Translated_317_residues
MPFPPARLMLKPAQLRLIQQIAETGQLQLAAERIGMTQPAASRMLAEIENQIGAQLFLRQPKGMEPTEIGRTVLRRARVI
LREMSSMASDVQALREGFGGALRVGAVTGPAVSYLVSAIREIKQGAPEADITVDVMPSRELLLHLAAEEMDFVLARILPE
FDSRDFNILPMRDEKVAFLVRASHPLSRSPSVTLTELAGQEWIMQQRGAPIREAALAAFADVGLSEPRNIVNSPSLLLTI
AYLAQGDAVAPMSEEVAELLIRPPVGAGFAVLQVPHEIRVSPYYLLDLKRRPLSPLAMRLREKLVALSQSPVRDAFG
>Mature_316_residues
PFPPARLMLKPAQLRLIQQIAETGQLQLAAERIGMTQPAASRMLAEIENQIGAQLFLRQPKGMEPTEIGRTVLRRARVIL
REMSSMASDVQALREGFGGALRVGAVTGPAVSYLVSAIREIKQGAPEADITVDVMPSRELLLHLAAEEMDFVLARILPEF
DSRDFNILPMRDEKVAFLVRASHPLSRSPSVTLTELAGQEWIMQQRGAPIREAALAAFADVGLSEPRNIVNSPSLLLTIA
YLAQGDAVAPMSEEVAELLIRPPVGAGFAVLQVPHEIRVSPYYLLDLKRRPLSPLAMRLREKLVALSQSPVRDAFG

Specific function: Activator of the expression of chvE when bound to its inducer and represses its expression in the absence of inducer (L- arabinose, D-fucose or D-galactose). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789506, Length=240, Percent_Identity=22.9166666666667, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787601, Length=294, Percent_Identity=22.7891156462585, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790399, Length=288, Percent_Identity=23.6111111111111, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787879, Length=192, Percent_Identity=26.5625, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081904, Length=241, Percent_Identity=27.8008298755187, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788481, Length=203, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786401, Length=141, Percent_Identity=26.9503546099291, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34763; Mature: 34632

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFPPARLMLKPAQLRLIQQIAETGQLQLAAERIGMTQPAASRMLAEIENQIGAQLFLRQ
CCCCCHHHHCCHHHHHHHHHHHHCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
PKGMEPTEIGRTVLRRARVILREMSSMASDVQALREGFGGALRVGAVTGPAVSYLVSAIR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHH
EIKQGAPEADITVDVMPSRELLLHLAAEEMDFVLARILPEFDSRDFNILPMRDEKVAFLV
HHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEE
RASHPLSRSPSVTLTELAGQEWIMQQRGAPIREAALAAFADVGLSEPRNIVNSPSLLLTI
EECCCCCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
AYLAQGDAVAPMSEEVAELLIRPPVGAGFAVLQVPHEIRVSPYYLLDLKRRPLSPLAMRL
HHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCHHHCCCCEEEEECCCCCCCHHHHHH
REKLVALSQSPVRDAFG
HHHHHHHCCCCCHHCCC
>Mature Secondary Structure 
PFPPARLMLKPAQLRLIQQIAETGQLQLAAERIGMTQPAASRMLAEIENQIGAQLFLRQ
CCCCHHHHCCHHHHHHHHHHHHCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
PKGMEPTEIGRTVLRRARVILREMSSMASDVQALREGFGGALRVGAVTGPAVSYLVSAIR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHH
EIKQGAPEADITVDVMPSRELLLHLAAEEMDFVLARILPEFDSRDFNILPMRDEKVAFLV
HHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEE
RASHPLSRSPSVTLTELAGQEWIMQQRGAPIREAALAAFADVGLSEPRNIVNSPSLLLTI
EECCCCCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
AYLAQGDAVAPMSEEVAELLIRPPVGAGFAVLQVPHEIRVSPYYLLDLKRRPLSPLAMRL
HHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCHHHCCCCEEEEECCCCCCCHHHHHH
REKLVALSQSPVRDAFG
HHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8253677; 2156804 [H]