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The map label for this gene is znuA [H]

Identifier: 119386845

GI number: 119386845

Start: 1296748

End: 1297728

Strand: Direct

Name: znuA [H]

Synonym: Pden_4140

Alternate gene names: 119386845

Gene position: 1296748-1297728 (Clockwise)

Preceding gene: 119386840

Following gene: 119386846

Centisome position: 74.95

GC content: 67.69

Gene sequence:

>981_bases
ATGATCCGACCTTCTTCCCTTGTCCTTGCCGCTGCGCTTGGCACCGCCGCCCTGCCCGCCCGGGCCGAAGTCCCGCGGGT
GGTGACCGATATTCCCGTCGTCGGGGCCATGGTGCAGCAGGTCATGGGCGATCTGGGCCAGCCCGAGATCCTGCTGCAGG
CCGGCGGCGATCCGCACAGCTATCAGCTGCGTCCCAGCCAGGCCCGCAGCTTGCAGGATGCCGACCTGCTGATCTGGGTC
GGCCCCGAGCTGACCCCGTGGCTGGAGCGGGCCGCCACCAGCCTTTCCGCGCAGAGCGAGATGCTGGCCCTGCTGGACCT
GCCCGCCACGCATCGCCGGGACTATGCCGGCGGCGAGCATGAGCATGAGCATGAGCATGAGCATGAGCATGAGCATGAGC
ATGAGCATGATGGACACGGCCATGCCGAGGAGCAAGCGCATCACGACCACGACCACAGCGGCACCGATCCTCATGCCTGG
CTGGACCCGGCGAATGGGCAGGCCTGGCTTGCCGGCATCGCCGAGACCCTGTCCCGGCACGACCCGGACAATGCAGGCGT
CTATGCCGCCAATGCCGCGAAGGCCGCCGACGAAATCGCCGCGCTGGACGAAGAACTGAAATCGGCGCTGACCCCCACGC
AAGGCAAGCGCTTCGTCGTCTTTCATGACGCCTATGGCTATTTCACCGAGCATTACGGGCTGGAGCCGGCCATTGCGGTC
AGCCTTGGCGATGCCTCGACGCCCTCGGCCGCGCGGCTCAGGGCGATTCGCGACGAGATCGCCGAAGAGGGCGCGGTCTG
CGCTTTCCCCGAGGCGAATCACGATCCGAAACTGATTGCCGCGGTGATCGAGGGCAGCGAAATCCGCCAGGGCGCCGCGC
TCGACCCCGAAGGGACCGGCGCGACTCCCGGCGCCGGGCTTTATGCGGAGCTTCTGCGCGGCATGGGCCAGGCGCTGGCC
GATTGCCTTGGGGCTGACTAG

Upstream 100 bases:

>100_bases
GGGATTCCGAAGTGGGCATGATGTTATATCGTTACATTTTTGCTTGACGGGTTACGATATAACATAAATAACCTTGGCGT
TTCCGCAAGTGAGTCTCGCC

Downstream 100 bases:

>100_bases
GAACTGCCGGTAAATCCGTCCCCCTTCCGGGGCTTCAGCAAGGCGGGCGTCCATGTGGCGCCCGCCTTTTCGCTTTCAAA
ACGACGGGTTATGTGGCGGG

Product: periplasmic solute binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MIRPSSLVLAAALGTAALPARAEVPRVVTDIPVVGAMVQQVMGDLGQPEILLQAGGDPHSYQLRPSQARSLQDADLLIWV
GPELTPWLERAATSLSAQSEMLALLDLPATHRRDYAGGEHEHEHEHEHEHEHEHEHDGHGHAEEQAHHDHDHSGTDPHAW
LDPANGQAWLAGIAETLSRHDPDNAGVYAANAAKAADEIAALDEELKSALTPTQGKRFVVFHDAYGYFTEHYGLEPAIAV
SLGDASTPSAARLRAIRDEIAEEGAVCAFPEANHDPKLIAAVIEGSEIRQGAALDPEGTGATPGAGLYAELLRGMGQALA
DCLGAD

Sequences:

>Translated_326_residues
MIRPSSLVLAAALGTAALPARAEVPRVVTDIPVVGAMVQQVMGDLGQPEILLQAGGDPHSYQLRPSQARSLQDADLLIWV
GPELTPWLERAATSLSAQSEMLALLDLPATHRRDYAGGEHEHEHEHEHEHEHEHEHDGHGHAEEQAHHDHDHSGTDPHAW
LDPANGQAWLAGIAETLSRHDPDNAGVYAANAAKAADEIAALDEELKSALTPTQGKRFVVFHDAYGYFTEHYGLEPAIAV
SLGDASTPSAARLRAIRDEIAEEGAVCAFPEANHDPKLIAAVIEGSEIRQGAALDPEGTGATPGAGLYAELLRGMGQALA
DCLGAD
>Mature_326_residues
MIRPSSLVLAAALGTAALPARAEVPRVVTDIPVVGAMVQQVMGDLGQPEILLQAGGDPHSYQLRPSQARSLQDADLLIWV
GPELTPWLERAATSLSAQSEMLALLDLPATHRRDYAGGEHEHEHEHEHEHEHEHEHDGHGHAEEQAHHDHDHSGTDPHAW
LDPANGQAWLAGIAETLSRHDPDNAGVYAANAAKAADEIAALDEELKSALTPTQGKRFVVFHDAYGYFTEHYGLEPAIAV
SLGDASTPSAARLRAIRDEIAEEGAVCAFPEANHDPKLIAAVIEGSEIRQGAALDPEGTGATPGAGLYAELLRGMGQALA
DCLGAD

Specific function: Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in macrophages [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=302, Percent_Identity=29.8013245033113, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 34691; Mature: 34691

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPSSLVLAAALGTAALPARAEVPRVVTDIPVVGAMVQQVMGDLGQPEILLQAGGDPHS
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
YQLRPSQARSLQDADLLIWVGPELTPWLERAATSLSAQSEMLALLDLPATHRRDYAGGEH
EEECHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCC
EHEHEHEHEHEHEHEHDGHGHAEEQAHHDHDHSGTDPHAWLDPANGQAWLAGIAETLSRH
CHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHC
DPDNAGVYAANAAKAADEIAALDEELKSALTPTQGKRFVVFHDAYGYFTEHYGLEPAIAV
CCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCCCEEEE
SLGDASTPSAARLRAIRDEIAEEGAVCAFPEANHDPKLIAAVIEGSEIRQGAALDPEGTG
EECCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHEEEEECCCHHHCCCCCCCCCCCC
ATPGAGLYAELLRGMGQALADCLGAD
CCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRPSSLVLAAALGTAALPARAEVPRVVTDIPVVGAMVQQVMGDLGQPEILLQAGGDPHS
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
YQLRPSQARSLQDADLLIWVGPELTPWLERAATSLSAQSEMLALLDLPATHRRDYAGGEH
EEECHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCC
EHEHEHEHEHEHEHEHDGHGHAEEQAHHDHDHSGTDPHAWLDPANGQAWLAGIAETLSRH
CHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHC
DPDNAGVYAANAAKAADEIAALDEELKSALTPTQGKRFVVFHDAYGYFTEHYGLEPAIAV
CCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCCCEEEE
SLGDASTPSAARLRAIRDEIAEEGAVCAFPEANHDPKLIAAVIEGSEIRQGAALDPEGTG
EECCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHEEEEECCCHHHCCCCCCCCCCCC
ATPGAGLYAELLRGMGQALADCLGAD
CCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA