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The map label for this gene is lldD [H]

Identifier: 119386782

GI number: 119386782

Start: 1230311

End: 1231474

Strand: Direct

Name: lldD [H]

Synonym: Pden_4075

Alternate gene names: 119386782

Gene position: 1230311-1231474 (Clockwise)

Preceding gene: 119386778

Following gene: 119386784

Centisome position: 71.11

GC content: 66.58

Gene sequence:

>1164_bases
ATGCCGGTCATCACCTGCATCGACGACCTGAAGGCGATCTATCGCAGGCGCGTGCCGCGCATGTTCTACGACTACGCCGA
AAGCGGCAGCTATACCGAGGGCACCTTCCGCGAGAACTGCACCGATTTCCAGCGCATCAAGCTGCGCCAGCGCGTCGCGG
TGGACATGACGGGGCGCACCACCGAAAGCACGATGATCGGGCAAAAGGTCGCAATGCCGGTGGCGCTGGCCCCGGTCGGC
ATGACCGGCATGCAATGCGCCGATGGCGAGATCAAGGCGGCGCGCGCCGCGAAGGCCTTTGGCGTGCCCTTCACCCTTTC
GACCATGTCGATCTGCTCGATCGAGGACGTGGCCGAGGCGGTCCAGGCGCCCTTCTGGTTCCAGCTCTACGTCATGCGCG
ACCAGGAATTCCTGGAGGCGATCATCGAGCGGGCCAGGCGCGCCAATTGCTCGGCGCTGGTGCTGACGCTGGACCTGCAG
ATCCTGGGCCAGCGCCACAAGGATCTGAAGAACGGGCTGTCGGCGCCGCCGCGGCTGACCCTGCCGGTGCTGCTGGACCT
GGCGACGAAATGGCGCTGGGGCATCGAGATGCTGCGCACGAAGCGCCGCTTCTTCGGCAATATCGTCGGCCATGCCAAGG
GGGTGGGCGACCCCTCGTCGCTGATCGCCTGGACGGCCGAGCAGTTCGACCCGCAGCTCGACTGGGGCAAGATCGCCCGC
ATCCGCGACCTCTGGGGCGGCAAGCTGATCCTCAAGGGCATCAACGATCCCGAGGATGCCCGCATGGCCGCGGATTTCGG
TGCCGATGCGATCATCGTCAGCAACCATGGCGGCCGGCAACTGGACGGCGCGGTCAGTTCGATCCGCATGCTGCCCGAGA
TCGTCAAGGCGGTGGGCGACCGGGTCGAGATCCATCTCGACAGCGGCATCCGCTCGGGCCAGGACGTCTTGAAGGCGCTG
GCCATGGGCGCCCATGCCACCCATATCGGCCGAGCCTTCATCTATGGGCTGGGCGCCATGGGCGAGGCCGGCGTGACTCG
CGCGCTGGAGGTGATCCAGAAGGAGCTGGACATCACCATGGCGCTGTGCGGCGAGCGCGACGTGAAGGCCCTGGGGCGGC
ACAACCTGCTGATCCCGCCGGATTTCCTGCAAGCCTGGGCCTGA

Upstream 100 bases:

>100_bases
CCCGGGCCCGCGCGCTTTCGCAGCAATCCCTGGCCGAGGACTGCCCCGAAGGCAGCACCGACTGCCCGCCGAACTGACCC
GCCGAACCGAGGAGAACACC

Downstream 100 bases:

>100_bases
TTCCCGCCAGGGCGCGGCGGCCACGCCACCTAGCGATAGGCGCGCTTGCTGCGCAACGAGGGCAGCAGGCGCGGCAGCAG
CCGTTGGAACGCGGCGGCGA

Product: L-lactate dehydrogenase (cytochrome)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MPVITCIDDLKAIYRRRVPRMFYDYAESGSYTEGTFRENCTDFQRIKLRQRVAVDMTGRTTESTMIGQKVAMPVALAPVG
MTGMQCADGEIKAARAAKAFGVPFTLSTMSICSIEDVAEAVQAPFWFQLYVMRDQEFLEAIIERARRANCSALVLTLDLQ
ILGQRHKDLKNGLSAPPRLTLPVLLDLATKWRWGIEMLRTKRRFFGNIVGHAKGVGDPSSLIAWTAEQFDPQLDWGKIAR
IRDLWGGKLILKGINDPEDARMAADFGADAIIVSNHGGRQLDGAVSSIRMLPEIVKAVGDRVEIHLDSGIRSGQDVLKAL
AMGAHATHIGRAFIYGLGAMGEAGVTRALEVIQKELDITMALCGERDVKALGRHNLLIPPDFLQAWA

Sequences:

>Translated_387_residues
MPVITCIDDLKAIYRRRVPRMFYDYAESGSYTEGTFRENCTDFQRIKLRQRVAVDMTGRTTESTMIGQKVAMPVALAPVG
MTGMQCADGEIKAARAAKAFGVPFTLSTMSICSIEDVAEAVQAPFWFQLYVMRDQEFLEAIIERARRANCSALVLTLDLQ
ILGQRHKDLKNGLSAPPRLTLPVLLDLATKWRWGIEMLRTKRRFFGNIVGHAKGVGDPSSLIAWTAEQFDPQLDWGKIAR
IRDLWGGKLILKGINDPEDARMAADFGADAIIVSNHGGRQLDGAVSSIRMLPEIVKAVGDRVEIHLDSGIRSGQDVLKAL
AMGAHATHIGRAFIYGLGAMGEAGVTRALEVIQKELDITMALCGERDVKALGRHNLLIPPDFLQAWA
>Mature_386_residues
PVITCIDDLKAIYRRRVPRMFYDYAESGSYTEGTFRENCTDFQRIKLRQRVAVDMTGRTTESTMIGQKVAMPVALAPVGM
TGMQCADGEIKAARAAKAFGVPFTLSTMSICSIEDVAEAVQAPFWFQLYVMRDQEFLEAIIERARRANCSALVLTLDLQI
LGQRHKDLKNGLSAPPRLTLPVLLDLATKWRWGIEMLRTKRRFFGNIVGHAKGVGDPSSLIAWTAEQFDPQLDWGKIARI
RDLWGGKLILKGINDPEDARMAADFGADAIIVSNHGGRQLDGAVSSIRMLPEIVKAVGDRVEIHLDSGIRSGQDVLKALA
MGAHATHIGRAFIYGLGAMGEAGVTRALEVIQKELDITMALCGERDVKALGRHNLLIPPDFLQAWA

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=374, Percent_Identity=35.8288770053476, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI54234014, Length=372, Percent_Identity=34.6774193548387, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI7705393, Length=372, Percent_Identity=34.6774193548387, Blast_Score=215, Evalue=7e-56,
Organism=Escherichia coli, GI1790033, Length=380, Percent_Identity=43.421052631579, Blast_Score=331, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI193208036, Length=375, Percent_Identity=34.6666666666667, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI32566217, Length=292, Percent_Identity=32.8767123287671, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6323587, Length=372, Percent_Identity=27.9569892473118, Blast_Score=161, Evalue=1e-40,
Organism=Drosophila melanogaster, GI78707188, Length=366, Percent_Identity=35.792349726776, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI281363140, Length=366, Percent_Identity=35.792349726776, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI78707190, Length=366, Percent_Identity=35.792349726776, Blast_Score=223, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 42694; Mature: 42563

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVITCIDDLKAIYRRRVPRMFYDYAESGSYTEGTFRENCTDFQRIKLRQRVAVDMTGRT
CCEEEHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHEEEECCCC
TESTMIGQKVAMPVALAPVGMTGMQCADGEIKAARAAKAFGVPFTLSTMSICSIEDVAEA
CHHHHHHHHHHCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHH
VQAPFWFQLYVMRDQEFLEAIIERARRANCSALVLTLDLQILGQRHKDLKNGLSAPPRLT
HCCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCH
LPVLLDLATKWRWGIEMLRTKRRFFGNIVGHAKGVGDPSSLIAWTAEQFDPQLDWGKIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEHHHCCCCCCHHHHHH
IRDLWGGKLILKGINDPEDARMAADFGADAIIVSNHGGRQLDGAVSSIRMLPEIVKAVGD
HHHHCCCEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
RVEIHLDSGIRSGQDVLKALAMGAHATHIGRAFIYGLGAMGEAGVTRALEVIQKELDITM
EEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
ALCGERDVKALGRHNLLIPPDFLQAWA
HHCCCHHHHHHCCCCCCCCHHHHHHCC
>Mature Secondary Structure 
PVITCIDDLKAIYRRRVPRMFYDYAESGSYTEGTFRENCTDFQRIKLRQRVAVDMTGRT
CEEEHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHEEEECCCC
TESTMIGQKVAMPVALAPVGMTGMQCADGEIKAARAAKAFGVPFTLSTMSICSIEDVAEA
CHHHHHHHHHHCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHH
VQAPFWFQLYVMRDQEFLEAIIERARRANCSALVLTLDLQILGQRHKDLKNGLSAPPRLT
HCCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCH
LPVLLDLATKWRWGIEMLRTKRRFFGNIVGHAKGVGDPSSLIAWTAEQFDPQLDWGKIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEHHHCCCCCCHHHHHH
IRDLWGGKLILKGINDPEDARMAADFGADAIIVSNHGGRQLDGAVSSIRMLPEIVKAVGD
HHHHCCCEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
RVEIHLDSGIRSGQDVLKALAMGAHATHIGRAFIYGLGAMGEAGVTRALEVIQKELDITM
EEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
ALCGERDVKALGRHNLLIPPDFLQAWA
HHCCCHHHHHHCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA