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The map label for this gene is lin [H]

Identifier: 119386722

GI number: 119386722

Start: 1162011

End: 1162808

Strand: Direct

Name: lin [H]

Synonym: Pden_4015

Alternate gene names: 119386722

Gene position: 1162011-1162808 (Clockwise)

Preceding gene: 119386721

Following gene: 119386723

Centisome position: 67.16

GC content: 68.3

Gene sequence:

>798_bases
ATGGACAATCTTCATCGCAAACTGGCGCCGATCAGCGATGCGGCCTGGGCCCAGATCGAGGACGAGGCGGCGCGGACGCT
GAAACGCTATCTCGGCGCGCGGCGGGTGGTGGATGTGCACGGCCCGGAAGGGTTCGGCCTGTCGGCGGTGGGCACCGGCC
ATCTGCGTCCCGCCACGGCGCTGGCCGAGGGCGTCGAAAGCCACCGGCGCGAGGTGAACCCGCTGCTGGAATTGCGCGTG
CCCTTTACCCTGACCCGCGCCGCCATCGACGACGTGGCGCGCGGCTCGAACGACAGCGACTGGCAGCCGCTGAAGGACGC
AGCGCGCAAGATCGCGCTGGCCGAGGACCGGCTGGTCTTTCTGGGCCATGGCGATGCGGGCATCAGGGGCATCCTGCCGG
AAACCAGCAACCCCATCGTCGCGCTGCCCGCAAATGTCGCCGACTATCCCGAGGCGGTGGCCTCGGCGGTCAGCGAGTTG
CGGCTGGCAGGGGTCAACGGACCCTATGCGCTGATCCTGGGAACGACGGCCTTCACCGCCGCCAATGGCGGCGCCGAGGA
CGGCTATCCGGTGCTGAAGCATCTGGAGCGGCTGGTCGATGTGCCGGTGGTCTGGAGCCAGGCGCTGGAGGGCGGGGCCG
TCGTCACCACCCGCGGCGGCGATTTCGACCTGTGGCTGGGGCAGGACATCTCGATCGGCTATCTGTCGCACGACGCTGCA
TCCGTCACGCTTTACCTGCAGGAATCCCTGACCTTCCAGATGCAGACATCCGAAGCCGTGGTGGCGCTGAAGGCCTGA

Upstream 100 bases:

>100_bases
GGCGCGGGCCGGCCCGTGCAGCAACCGGCAGCAAAACCGGAACCCGCCGTGCGGACGGATGGCTCGCTCGGCCTTGGATC
CTTGAAACAGGGGAACTGAC

Downstream 100 bases:

>100_bases
CCACCGATGACGCCACGCTCGCAGCCCAACCTGCGCGATATCCTGCTTACCCTCAACGGTTCGATCATTCCGGTGATCCT
GGGCCGCCTGACGGTGATCG

Product: Linocin_M18 bacteriocin protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MDNLHRKLAPISDAAWAQIEDEAARTLKRYLGARRVVDVHGPEGFGLSAVGTGHLRPATALAEGVESHRREVNPLLELRV
PFTLTRAAIDDVARGSNDSDWQPLKDAARKIALAEDRLVFLGHGDAGIRGILPETSNPIVALPANVADYPEAVASAVSEL
RLAGVNGPYALILGTTAFTAANGGAEDGYPVLKHLERLVDVPVVWSQALEGGAVVTTRGGDFDLWLGQDISIGYLSHDAA
SVTLYLQESLTFQMQTSEAVVALKA

Sequences:

>Translated_265_residues
MDNLHRKLAPISDAAWAQIEDEAARTLKRYLGARRVVDVHGPEGFGLSAVGTGHLRPATALAEGVESHRREVNPLLELRV
PFTLTRAAIDDVARGSNDSDWQPLKDAARKIALAEDRLVFLGHGDAGIRGILPETSNPIVALPANVADYPEAVASAVSEL
RLAGVNGPYALILGTTAFTAANGGAEDGYPVLKHLERLVDVPVVWSQALEGGAVVTTRGGDFDLWLGQDISIGYLSHDAA
SVTLYLQESLTFQMQTSEAVVALKA
>Mature_265_residues
MDNLHRKLAPISDAAWAQIEDEAARTLKRYLGARRVVDVHGPEGFGLSAVGTGHLRPATALAEGVESHRREVNPLLELRV
PFTLTRAAIDDVARGSNDSDWQPLKDAARKIALAEDRLVFLGHGDAGIRGILPETSNPIVALPANVADYPEAVASAVSEL
RLAGVNGPYALILGTTAFTAANGGAEDGYPVLKHLERLVDVPVVWSQALEGGAVVTTRGGDFDLWLGQDISIGYLSHDAA
SVTLYLQESLTFQMQTSEAVVALKA

Specific function: Bacteriocin that has antimicrobial activity against a wide range of Gram-positive bacteria, including L.monocytogenes, B.cereus and S.aureus. May have a protease activity [H]

COG id: COG1659

COG function: function code S; Uncharacterized protein, linocin/CFP29 homolog

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007544 [H]

Pfam domain/function: PF04454 Linocin_M18 [H]

EC number: NA

Molecular weight: Translated: 28204; Mature: 28204

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNLHRKLAPISDAAWAQIEDEAARTLKRYLGARRVVDVHGPEGFGLSAVGTGHLRPATA
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEECCCCCCHHHH
LAEGVESHRREVNPLLELRVPFTLTRAAIDDVARGSNDSDWQPLKDAARKIALAEDRLVF
HHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEECCCEEE
LGHGDAGIRGILPETSNPIVALPANVADYPEAVASAVSELRLAGVNGPYALILGTTAFTA
EECCCCCCEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHEEECCCCCEEEEEECHHHEE
ANGGAEDGYPVLKHLERLVDVPVVWSQALEGGAVVTTRGGDFDLWLGQDISIGYLSHDAA
CCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCEEEEECCCCEEEEECCCCEEEEEECCCE
SVTLYLQESLTFQMQTSEAVVALKA
EEEEEEEECEEEEEECCCEEEEEEC
>Mature Secondary Structure
MDNLHRKLAPISDAAWAQIEDEAARTLKRYLGARRVVDVHGPEGFGLSAVGTGHLRPATA
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEECCCCCCHHHH
LAEGVESHRREVNPLLELRVPFTLTRAAIDDVARGSNDSDWQPLKDAARKIALAEDRLVF
HHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEECCCEEE
LGHGDAGIRGILPETSNPIVALPANVADYPEAVASAVSELRLAGVNGPYALILGTTAFTA
EECCCCCCEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHEEECCCCCEEEEEECHHHEE
ANGGAEDGYPVLKHLERLVDVPVVWSQALEGGAVVTTRGGDFDLWLGQDISIGYLSHDAA
CCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCEEEEECCCCEEEEECCCCEEEEEECCCE
SVTLYLQESLTFQMQTSEAVVALKA
EEEEEEEECEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8919789 [H]