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The map label for this gene is ychE [H]

Identifier: 119386720

GI number: 119386720

Start: 1160292

End: 1160924

Strand: Direct

Name: ychE [H]

Synonym: Pden_4013

Alternate gene names: 119386720

Gene position: 1160292-1160924 (Clockwise)

Preceding gene: 119386719

Following gene: 119386721

Centisome position: 67.07

GC content: 67.3

Gene sequence:

>633_bases
ATGGCCGACGACATCCGGTTCGCCGTCAAGGTCTTCGCGGCCTTGTTCGCGATCATGAACCCGATTGCGAATGTCCCGAT
CTTCCTGCCCCTGACCGAAGGCGGCAGCGACGCCCAACGGCATCGCACCGCCGTCGTGGCGATCATCGCGGTCGGCATCG
GCTGCGTGGTCTCGGCGCTGGCCGGGGGTGCGGTGCTGTCGGCCTTCGGCCTGACGGTGGATGATTTCCGCCTTGCGGGC
GGGCTGATGGTGCTGCTGATCGCGCTGTCGATGCTGAACGGGTCCGCCAGCGCGCAGCACAAGCCCGCGGATCACGAGAT
CGACGGGACCGCTCCTTCGGTCGCGATCTATCCGCTTGCGGTCCCGCTGCTGGTCGGACCCGGCACCATCGCCACGCTGA
TCGTCTTTGGCCATGCCGCGATCTCGCAGGGGCTCGAGATCGGGCTGGCGCTTGGCCTTGGCGGTTTCCTGGTGGTTCTG
GCGGCGGCGCTTCTGACGGCGCCGTGGCTCGGCCATCATCTTTCCGCACAGGCGACGGCCGTCACCCGCCGGCTGATGGG
CATGCTTCTGGCCGCCATCGCCGTCGAGATGATGACGACCAGTATCAGGGCCTTGTTCCTGTCGGGGCGATAG

Upstream 100 bases:

>100_bases
AAGAGGCGGCAGGCGACAAACCCGCCTCCTGATTCGCTTGTCACGGAAATACCCCGGCGCCCCGGTGCCCCGGTGCCGGG
CCAAGGCAACAGGAGCATGC

Downstream 100 bases:

>100_bases
CGGATGCTTTCGCAAGCCGCCCGGACAGGCTTTACCGGACCCGTGCCAGCAAGGGAATGCCAATGACTCCGATCGCCAGC
CAGCCCGCCGACGGGTCCCT

Product: multiple antibiotic resistance (MarC)-related proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MADDIRFAVKVFAALFAIMNPIANVPIFLPLTEGGSDAQRHRTAVVAIIAVGIGCVVSALAGGAVLSAFGLTVDDFRLAG
GLMVLLIALSMLNGSASAQHKPADHEIDGTAPSVAIYPLAVPLLVGPGTIATLIVFGHAAISQGLEIGLALGLGGFLVVL
AAALLTAPWLGHHLSAQATAVTRRLMGMLLAAIAVEMMTTSIRALFLSGR

Sequences:

>Translated_210_residues
MADDIRFAVKVFAALFAIMNPIANVPIFLPLTEGGSDAQRHRTAVVAIIAVGIGCVVSALAGGAVLSAFGLTVDDFRLAG
GLMVLLIALSMLNGSASAQHKPADHEIDGTAPSVAIYPLAVPLLVGPGTIATLIVFGHAAISQGLEIGLALGLGGFLVVL
AAALLTAPWLGHHLSAQATAVTRRLMGMLLAAIAVEMMTTSIRALFLSGR
>Mature_209_residues
ADDIRFAVKVFAALFAIMNPIANVPIFLPLTEGGSDAQRHRTAVVAIIAVGIGCVVSALAGGAVLSAFGLTVDDFRLAGG
LMVLLIALSMLNGSASAQHKPADHEIDGTAPSVAIYPLAVPLLVGPGTIATLIVFGHAAISQGLEIGLALGLGGFLVVLA
AALLTAPWLGHHLSAQATAVTRRLMGMLLAAIAVEMMTTSIRALFLSGR

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787494, Length=205, Percent_Identity=34.1463414634146, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789842, Length=193, Percent_Identity=31.0880829015544, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787809, Length=121, Percent_Identity=35.5371900826446, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 21382; Mature: 21251

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADDIRFAVKVFAALFAIMNPIANVPIFLPLTEGGSDAQRHRTAVVAIIAVGIGCVVSAL
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGGAVLSAFGLTVDDFRLAGGLMVLLIALSMLNGSASAQHKPADHEIDGTAPSVAIYPLA
HCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHH
VPLLVGPGTIATLIVFGHAAISQGLEIGLALGLGGFLVVLAAALLTAPWLGHHLSAQATA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTRRLMGMLLAAIAVEMMTTSIRALFLSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ADDIRFAVKVFAALFAIMNPIANVPIFLPLTEGGSDAQRHRTAVVAIIAVGIGCVVSAL
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGGAVLSAFGLTVDDFRLAGGLMVLLIALSMLNGSASAQHKPADHEIDGTAPSVAIYPLA
HCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHH
VPLLVGPGTIATLIVFGHAAISQGLEIGLALGLGGFLVVLAAALLTAPWLGHHLSAQATA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTRRLMGMLLAAIAVEMMTTSIRALFLSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2015910; 9097039; 9278503 [H]