Click here to switch to the map view.

The map label for this gene is sufC [H]

Identifier: 119386673

GI number: 119386673

Start: 1104253

End: 1105008

Strand: Direct

Name: sufC [H]

Synonym: Pden_3966

Alternate gene names: 119386673

Gene position: 1104253-1105008 (Clockwise)

Preceding gene: 119386672

Following gene: 119386674

Centisome position: 63.83

GC content: 64.02

Gene sequence:

>756_bases
ATGCTGGAAATCAAGAATCTGCACGTCAAGCTTGAGGATGAGGACAAGCAGATCCTCAAAGGCGTCGATCTGACCGTCCC
CGCTGGCGAGGTCCATGCCATCATGGGGCCGAACGGCTCGGGCAAGTCGACGCTGTCCTATGTGCTTTCGGGCCGCGACG
GCTACGAGGTGACCGGGGGCGAGGCGACGCTGGACGGCGAAAGCCTGCTGGAGATGGAACCCGAGGAGCGTGCGGCCGCT
GGCCTGTTCCTGGCCTTCCAGTATCCGGTCGAGATCCCGGGCGTCGGCAACATGACCTTCCTGCGCACCGCCGTGAACGC
GCAGCGCAAGGCGCGCGGCGAGGAAGAGCTTTCCTCGGCCGATTTCCTCAAGCTGATCCGCCAGAAGGCCGCGACGCTGA
AGATCGACAGCGAGATGCTGAAGCGCCCGGTCAATGTCGGCTTCTCGGGTGGCGAGAAAAAGCGCAACGAGATCTTGCAG
ATGGCCATGCTGGAGCCGAGCATGTGCATCCTGGACGAGACCGATTCCGGCCTTGACGTGGACGCGATGCGGCTGGTGGC
CGAGGGCGTGAACGCGCTGCGTTCGCCCGACCGCGCCTTTCTGGTGATCACACATTACCAGCGGCTTCTGGACCATATCA
AGCCGGACGTGGTGCATATCATGGCCGATGGCCGCATCGTGCGCACCGGCGGCCCCGAACTGGCGCTGGAGGTCGAGCAG
AACGGCTACGGCGATCTGCTGGCGGAGGTCGGATGA

Upstream 100 bases:

>100_bases
CAATGCCGTGGTCGGCGTCGATCTGGATTATGAAGTCATCAACAACATGCTGATGGTGTCCGCCTCGGGCACCGCCGTAA
GTGTCGAATAGGAACGAACC

Downstream 100 bases:

>100_bases
TGGCGGATACGGCTGTTCTTGCCGCGCAAGTGCCTGCGGTCGAGGGCAAGGTCCGCCCCGGAGATGCGGCGCTGGCCGCA
CGCCTGGATGCCCTGGACCT

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLEIKNLHVKLEDEDKQILKGVDLTVPAGEVHAIMGPNGSGKSTLSYVLSGRDGYEVTGGEATLDGESLLEMEPEERAAA
GLFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEELSSADFLKLIRQKAATLKIDSEMLKRPVNVGFSGGEKKRNEILQ
MAMLEPSMCILDETDSGLDVDAMRLVAEGVNALRSPDRAFLVITHYQRLLDHIKPDVVHIMADGRIVRTGGPELALEVEQ
NGYGDLLAEVG

Sequences:

>Translated_251_residues
MLEIKNLHVKLEDEDKQILKGVDLTVPAGEVHAIMGPNGSGKSTLSYVLSGRDGYEVTGGEATLDGESLLEMEPEERAAA
GLFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEELSSADFLKLIRQKAATLKIDSEMLKRPVNVGFSGGEKKRNEILQ
MAMLEPSMCILDETDSGLDVDAMRLVAEGVNALRSPDRAFLVITHYQRLLDHIKPDVVHIMADGRIVRTGGPELALEVEQ
NGYGDLLAEVG
>Mature_251_residues
MLEIKNLHVKLEDEDKQILKGVDLTVPAGEVHAIMGPNGSGKSTLSYVLSGRDGYEVTGGEATLDGESLLEMEPEERAAA
GLFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEELSSADFLKLIRQKAATLKIDSEMLKRPVNVGFSGGEKKRNEILQ
MAMLEPSMCILDETDSGLDVDAMRLVAEGVNALRSPDRAFLVITHYQRLLDHIKPDVVHIMADGRIVRTGGPELALEVEQ
NGYGDLLAEVG

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=228, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1787972, Length=246, Percent_Identity=60.5691056910569, Blast_Score=311, Evalue=2e-86,
Organism=Escherichia coli, GI1787029, Length=241, Percent_Identity=26.5560165975104, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790525, Length=221, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1787370, Length=230, Percent_Identity=24.3478260869565, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787143, Length=231, Percent_Identity=26.4069264069264, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87082267, Length=202, Percent_Identity=27.2277227722772, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789891, Length=233, Percent_Identity=27.8969957081545, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI87081709, Length=220, Percent_Identity=24.5454545454545, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=253, Percent_Identity=28.8537549407115, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI212646699, Length=234, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI115533592, Length=225, Percent_Identity=27.5555555555556, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71996809, Length=219, Percent_Identity=26.9406392694064, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17541710, Length=219, Percent_Identity=26.4840182648402, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=242, Percent_Identity=29.7520661157025, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21357907, Length=233, Percent_Identity=27.0386266094421, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27345; Mature: 27345

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIKNLHVKLEDEDKQILKGVDLTVPAGEVHAIMGPNGSGKSTLSYVLSGRDGYEVTGG
CCEEEEEEEEECCCHHHHHCCCCEEECCCCEEEEECCCCCCCCEEHHEEECCCCCEECCC
EATLDGESLLEMEPEERAAAGLFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEELSSA
CEEECCCHHCCCCCHHHHHHEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHH
DFLKLIRQKAATLKIDSEMLKRPVNVGFSGGEKKRNEILQMAMLEPSMCILDETDSGLDV
HHHHHHHHHHHEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCH
DAMRLVAEGVNALRSPDRAFLVITHYQRLLDHIKPDVVHIMADGRIVRTGGPELALEVEQ
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCEEEEEECCEEEEECCCEEEEEECC
NGYGDLLAEVG
CCCCHHHHCCC
>Mature Secondary Structure
MLEIKNLHVKLEDEDKQILKGVDLTVPAGEVHAIMGPNGSGKSTLSYVLSGRDGYEVTGG
CCEEEEEEEEECCCHHHHHCCCCEEECCCCEEEEECCCCCCCCEEHHEEECCCCCEECCC
EATLDGESLLEMEPEERAAAGLFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEELSSA
CEEECCCHHCCCCCHHHHHHEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHH
DFLKLIRQKAATLKIDSEMLKRPVNVGFSGGEKKRNEILQMAMLEPSMCILDETDSGLDV
HHHHHHHHHHHEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCH
DAMRLVAEGVNALRSPDRAFLVITHYQRLLDHIKPDVVHIMADGRIVRTGGPELALEVEQ
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCEEEEEECCEEEEECCCEEEEEECC
NGYGDLLAEVG
CCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]