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The map label for this gene is sugE [H]

Identifier: 119386655

GI number: 119386655

Start: 1084256

End: 1084576

Strand: Direct

Name: sugE [H]

Synonym: Pden_3948

Alternate gene names: 119386655

Gene position: 1084256-1084576 (Clockwise)

Preceding gene: 119386653

Following gene: 119386656

Centisome position: 62.67

GC content: 65.73

Gene sequence:

>321_bases
ATGGCGTGGATCTATCTGGGTGTGGCGGGGTTGTACGAGGTGATCTGGGCCTTTGCCATGAAGCAGTCCGACGGCTTCAC
CCGGCCCTGGGCGACCGCGACCACCCTTGTCGCCATGGCGGCCAGCGTCTGGTTCCTGTCGCTGTCGATGAAGGTGCTGC
CCCTGGGCACCGCCTATGTCATCTGGACGGGCATCGGCGCGGTCGGCACCTTCGTTCTGGGGGTGCTGCTGCTGGGCGAA
TCGGCCGATTCGCTGCGCCTTCTCGCGGCGGTGCTGATCGTTGCGGGCCTGGTGCTGATGAAGATCGCCTCGCCGCATTG
A

Upstream 100 bases:

>100_bases
TCATGCCGCCATCTTGCCAGCAATCCTTCGGTGGGGCCAGCCCGGCTTGACCTTGCCCCATGCGCCGCCACAACCTGCCC
GGCAGGACAGGAGGCAAGGC

Downstream 100 bases:

>100_bases
GCCTTGTCACGCCGCTGTCACGCCGCAGGGCTATTTGTGTGCCAGGCATATATTCAGGGACTTGTCAGCCCGGAACCGCG
ATATATAGTCGGTGCCATGT

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MAWIYLGVAGLYEVIWAFAMKQSDGFTRPWATATTLVAMAASVWFLSLSMKVLPLGTAYVIWTGIGAVGTFVLGVLLLGE
SADSLRLLAAVLIVAGLVLMKIASPH

Sequences:

>Translated_106_residues
MAWIYLGVAGLYEVIWAFAMKQSDGFTRPWATATTLVAMAASVWFLSLSMKVLPLGTAYVIWTGIGAVGTFVLGVLLLGE
SADSLRLLAAVLIVAGLVLMKIASPH
>Mature_105_residues
AWIYLGVAGLYEVIWAFAMKQSDGFTRPWATATTLVAMAASVWFLSLSMKVLPLGTAYVIWTGIGAVGTFVLGVLLLGES
ADSLRLLAAVLIVAGLVLMKIASPH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=48.0769230769231, Blast_Score=97, Evalue=3e-22,
Organism=Escherichia coli, GI1786755, Length=107, Percent_Identity=37.3831775700935, Blast_Score=69, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11243; Mature: 11111

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWIYLGVAGLYEVIWAFAMKQSDGFTRPWATATTLVAMAASVWFLSLSMKVLPLGTAYV
CEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
IWTGIGAVGTFVLGVLLLGESADSLRLLAAVLIVAGLVLMKIASPH
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AWIYLGVAGLYEVIWAFAMKQSDGFTRPWATATTLVAMAASVWFLSLSMKVLPLGTAYV
EEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
IWTGIGAVGTFVLGVLLLGESADSLRLLAAVLIVAGLVLMKIASPH
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]