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The map label for this gene is aacC1 [H]

Identifier: 119386069

GI number: 119386069

Start: 509912

End: 510370

Strand: Direct

Name: aacC1 [H]

Synonym: Pden_3355

Alternate gene names: 119386069

Gene position: 509912-510370 (Clockwise)

Preceding gene: 119386068

Following gene: 119386070

Centisome position: 29.47

GC content: 63.83

Gene sequence:

>459_bases
ATGTCCGTGTCGATCAGGTGCCTGGGCCGATCCGACGTTTCCGTCCTGCGGCAGATGAACGCCTTGTTCGGGGATGCCTT
CGACGATCCCGACACCTACCTGGGAGAGCCGCCGGACGACGCCTATCTGAGCGGCCTTCTGGCCGGGGATCATCTCATCG
CGCTGGCGGCCATGGACGGCGCCGTCGTCGTCGGCGGCCTGATCGCCTACGAGCTCGAGAAATTTGAGCGGGCGCGTTCG
GAAATCTACATCTACGATCTTGCTGTCGCCGAGACCCACCGGCGCCAGGGCATAGCCACCGCGCTCATCGGTACCTTGCA
ACGGATCGCGGCCGAACGGGGCGCCTGGGTGGTTTACGTTCAGGCCGATTACGGGGATGAGCCGGCCATTGCCCTCTATA
CCGGGCTTGGAAAGCGCGAGGACGTCCTGCATTTCGACATTCCGGTCGATGCGGGATAG

Upstream 100 bases:

>100_bases
TCGTCGAGGCGATCCTCGCGGACGAGACCATTTGGACATGGCCCGATGCGCAGGGGCGGTTCAGGGTATGATACACCTGA
AGCATGAGGAGGAGTTGCCG

Downstream 100 bases:

>100_bases
TTGACGGACCTCATGAGCGCGTGGGCTGGCGGCTTGTCGCCGGCCATTGGCCATTGCCGGCAGCTATCCGCATCAATCCC
CGGTCCTCCGCCTGTCGGCT

Product: gentamicin 3'-N-acetyltransferase

Products: NA

Alternate protein names: AAC(3)-I; Aminoglycoside N(3')-acetyltransferase I; Gentamicin acetyltransferase I [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MSVSIRCLGRSDVSVLRQMNALFGDAFDDPDTYLGEPPDDAYLSGLLAGDHLIALAAMDGAVVVGGLIAYELEKFERARS
EIYIYDLAVAETHRRQGIATALIGTLQRIAAERGAWVVYVQADYGDEPAIALYTGLGKREDVLHFDIPVDAG

Sequences:

>Translated_152_residues
MSVSIRCLGRSDVSVLRQMNALFGDAFDDPDTYLGEPPDDAYLSGLLAGDHLIALAAMDGAVVVGGLIAYELEKFERARS
EIYIYDLAVAETHRRQGIATALIGTLQRIAAERGAWVVYVQADYGDEPAIALYTGLGKREDVLHFDIPVDAG
>Mature_151_residues
SVSIRCLGRSDVSVLRQMNALFGDAFDDPDTYLGEPPDDAYLSGLLAGDHLIALAAMDGAVVVGGLIAYELEKFERARSE
IYIYDLAVAETHRRQGIATALIGTLQRIAAERGAWVVYVQADYGDEPAIALYTGLGKREDVLHFDIPVDAG

Specific function: Responsible for gentamicin resistance and has a limited substrate range [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.60 [H]

Molecular weight: Translated: 16447; Mature: 16316

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSIRCLGRSDVSVLRQMNALFGDAFDDPDTYLGEPPDDAYLSGLLAGDHLIALAAMDG
CCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCC
AVVVGGLIAYELEKFERARSEIYIYDLAVAETHRRQGIATALIGTLQRIAAERGAWVVYV
HHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEE
QADYGDEPAIALYTGLGKREDVLHFDIPVDAG
ECCCCCCCCEEEEECCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SVSIRCLGRSDVSVLRQMNALFGDAFDDPDTYLGEPPDDAYLSGLLAGDHLIALAAMDG
CEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCC
AVVVGGLIAYELEKFERARSEIYIYDLAVAETHRRQGIATALIGTLQRIAAERGAWVVYV
HHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEE
QADYGDEPAIALYTGLGKREDVLHFDIPVDAG
ECCCCCCCCEEEEECCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2549372 [H]