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The map label for this gene is aacC3 [H]

Identifier: 119385876

GI number: 119385876

Start: 331073

End: 331906

Strand: Direct

Name: aacC3 [H]

Synonym: Pden_3154

Alternate gene names: 119385876

Gene position: 331073-331906 (Clockwise)

Preceding gene: 119385875

Following gene: 119385877

Centisome position: 19.14

GC content: 69.78

Gene sequence:

>834_bases
ATGCGCGGCAAGGCCTCGATCACGGCGGATCTTCGGCGGCTTGGCCTGAAACCGGGCGATCTGGTGATGGTCCACGCCTC
GCTGAAGGCGCTCGGCCCGGTCGAGGGTGGCGCGGCCGGGGTCGTCCAGGCGCTGCTGGATGCCTTGAGGCCGGGCGGCA
CGGTGATGGGATATGCCTCCTGGGACCGCTCCCCCTATGAGGAAACCCTGAACGGCGCCCGGATGGACGAGGCCCTGCGC
CGCGACTGGCCCGCCTTCGATCCCCGGACTGCCGGGACCTATCGCGGCTTCGGCTTGTTGAACCAATTCCTTGCGGACTT
GCCGGAGGCCCGGCGCAGCGCCCACCCGGATGCCTCGATGGTCGCGGTCGGCCCGCTGGCCGGGACCCTGGACGAGCCGC
ACCGGCTGGGCCAGGCCCTGCGCGAGGGCTCGCCGCTGGAACGCTTCGTCCGCCTTGGCGGCAAGACCCTGCTGCTGGGT
GCGCCGCTCGATGCCGTGACCGTGCTGCATTACGCCGAGGCCGTCGCCGACATCCCCGGCAAGCGCCGCGTCAGCTATGA
GATGCCGATGCCGGGCCCGGATGGCCGGACCATCTGGGAGGCTGCCACGGATTTCGACTCGAACGGCATCCTCGATTGCT
TCGCGGTCGAGGGCCAGCCGGATGCGGTCGAGACCATCGCCCGCGCTTATGTCGCGACGGGCCGGTACCGGGAGGGCATG
GTCGGCGCCGCGCGCTGCCATTTGTTCGACGCGCAGGATATCGTCGCCTTCGGGGTCGACTGGCTTGAGCGGCAGTTCGG
ATCGGTGCCTGAATCTGGGGAAGACCAAACCTGA

Upstream 100 bases:

>100_bases
ACCGCCGAGCGTGTCGGTCTGCTGAACGTCTTCATCCCCGGCGGGTTCGAGCGCGACATGCCCGCCATCGCCGACTGGTT
CAGGGACAATCCCTAGGCCC

Downstream 100 bases:

>100_bases
GGATCGACCGGCATGGCCCCGCGGATATCGAACCGGATCGCGTCTTTCGTCGACGCCCTGCCGCTGGCGCCGGGCCAGAG
GGTGCTGGAGATCGGCTGCG

Product: aminoglycoside N(3')-acetyltransferase

Products: NA

Alternate protein names: ACC(3)-III; Aminocyclitol 3-N-acetyltransferase type III; Gentamicin-(3)-N-acetyl-transferase [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MRGKASITADLRRLGLKPGDLVMVHASLKALGPVEGGAAGVVQALLDALRPGGTVMGYASWDRSPYEETLNGARMDEALR
RDWPAFDPRTAGTYRGFGLLNQFLADLPEARRSAHPDASMVAVGPLAGTLDEPHRLGQALREGSPLERFVRLGGKTLLLG
APLDAVTVLHYAEAVADIPGKRRVSYEMPMPGPDGRTIWEAATDFDSNGILDCFAVEGQPDAVETIARAYVATGRYREGM
VGAARCHLFDAQDIVAFGVDWLERQFGSVPESGEDQT

Sequences:

>Translated_277_residues
MRGKASITADLRRLGLKPGDLVMVHASLKALGPVEGGAAGVVQALLDALRPGGTVMGYASWDRSPYEETLNGARMDEALR
RDWPAFDPRTAGTYRGFGLLNQFLADLPEARRSAHPDASMVAVGPLAGTLDEPHRLGQALREGSPLERFVRLGGKTLLLG
APLDAVTVLHYAEAVADIPGKRRVSYEMPMPGPDGRTIWEAATDFDSNGILDCFAVEGQPDAVETIARAYVATGRYREGM
VGAARCHLFDAQDIVAFGVDWLERQFGSVPESGEDQT
>Mature_277_residues
MRGKASITADLRRLGLKPGDLVMVHASLKALGPVEGGAAGVVQALLDALRPGGTVMGYASWDRSPYEETLNGARMDEALR
RDWPAFDPRTAGTYRGFGLLNQFLADLPEARRSAHPDASMVAVGPLAGTLDEPHRLGQALREGSPLERFVRLGGKTLLLG
APLDAVTVLHYAEAVADIPGKRRVSYEMPMPGPDGRTIWEAATDFDSNGILDCFAVEGQPDAVETIARAYVATGRYREGM
VGAARCHLFDAQDIVAFGVDWLERQFGSVPESGEDQT

Specific function: Resistance to antibiotics containing the 2-deoxy- streptamine ring including gentamicin, kanamycin, tobramycin, neomycin and apramycin [H]

COG id: COG2746

COG function: function code V; Aminoglycoside N3'-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the antibiotic N-acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003679 [H]

Pfam domain/function: PF02522 Antibiotic_NAT [H]

EC number: =2.3.1.81 [H]

Molecular weight: Translated: 29760; Mature: 29760

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGKASITADLRRLGLKPGDLVMVHASLKALGPVEGGAAGVVQALLDALRPGGTVMGYAS
CCCCHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEECC
WDRSPYEETLNGARMDEALRRDWPAFDPRTAGTYRGFGLLNQFLADLPEARRSAHPDASM
CCCCHHHHHHCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
VAVGPLAGTLDEPHRLGQALREGSPLERFVRLGGKTLLLGAPLDAVTVLHYAEAVADIPG
EEECCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCC
KRRVSYEMPMPGPDGRTIWEAATDFDSNGILDCFAVEGQPDAVETIARAYVATGRYREGM
CCEEEEECCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHCCC
VGAARCHLFDAQDIVAFGVDWLERQFGSVPESGEDQT
CHHHHEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRGKASITADLRRLGLKPGDLVMVHASLKALGPVEGGAAGVVQALLDALRPGGTVMGYAS
CCCCHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEECC
WDRSPYEETLNGARMDEALRRDWPAFDPRTAGTYRGFGLLNQFLADLPEARRSAHPDASM
CCCCHHHHHHCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
VAVGPLAGTLDEPHRLGQALREGSPLERFVRLGGKTLLLGAPLDAVTVLHYAEAVADIPG
EEECCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCC
KRRVSYEMPMPGPDGRTIWEAATDFDSNGILDCFAVEGQPDAVETIARAYVATGRYREGM
CCEEEEECCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHCCC
VGAARCHLFDAQDIVAFGVDWLERQFGSVPESGEDQT
CHHHHEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3892230 [H]