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The map label for this gene is trxB [H]

Identifier: 119385842

GI number: 119385842

Start: 303759

End: 304643

Strand: Direct

Name: trxB [H]

Synonym: Pden_3120

Alternate gene names: 119385842

Gene position: 303759-304643 (Clockwise)

Preceding gene: 119385841

Following gene: 119385843

Centisome position: 17.56

GC content: 70.4

Gene sequence:

>885_bases
ATGCAGGACGTGATCGTGATCGGGGGCAGCTATGCCGGGATGGCCGCCGCCCTGCAGCTGGCGCGTGCGCGCCGCAAGGT
GCTGGTGATTGATGCCGGGCAGCGGCGCAACCGTTTCGCCAGCTATTCACACGGCTTCCTTGGCCAGGACGGGGTGGACC
CGGCCCGCATCTGGGCCGAGGCGTGCCGGCAGCTGCTGGCCTATCCGACGGTGACCTGGGTTGAGGGCTCGGCCAGCACC
ATCGCCGGCGGCAAGGACGAATTCCGTGTTTCCACGGCAGCCGGCGACACATTCGCGGGCCGCCGCATCCTGCTGGCCAC
AGGCGTCGCCGACCGGCTTCCCGACATTCCGGGTCTCGCCGACCGCTGGGGCCGGACGGTGTTCCACTGCCCCTATTGCC
ACGGTTACGAGCTGGACCAGGGCCGGATCGGGGTCATCGCCACCGGCGCGATGTCGCTTCATCAGGCGCAGCTGCTGCCG
GAATGGGGCGAGGTCACCTTCCTGACCAACGGCGCCCTGACACTGGAGCCGGAGCAGCGCGACGACTTGCGCAGCCGCGG
CGTTGCCATTGAGGAAACCCCCGTCGCCCGGATCGCGGGCGAGGCCGAGGTGGAACTGCGCGACGGCCGGGTGCTGCCCT
TCGCCGGTCTGTTCACCGCGACCGGGACCGAGCCGGCCAGCCCGCTGGCCGAGGCCGCCGGCTGCGAGTTGATCGAGACG
CCGATGGGCCGCCAGATCGTGACGGATGAGACGAAGGAAACCAGCCTTCCCGGCATCTTTGCCTGCGGCGACGTCGCGCG
GGCACCGCATTCGGTGTCACTGGCGGTGGGGGACGGGGCATGGGCCGGGGCGCAACTGCACCGCTCGCTGGTCTGGCCGG
AATGA

Upstream 100 bases:

>100_bases
GGCGCTGCTGCTGGAACGTTTCGCCGAGGTGACGCTGGCCGATCTGGCCGAGGATTTTGCCCGCCGCCATGCGCAGAGGC
GGGCGGCGAAGGAGTAGGAC

Downstream 100 bases:

>100_bases
GCGGCGCGGCCCATCCGGGCGACGGTGCCAGCTATGCCGGCCGCGTCGCGCGCCATGTGCCGGGCCTCAAGGACCTGCAC
CGCATGGCCGGGCTGCTGCT

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MQDVIVIGGSYAGMAAALQLARARRKVLVIDAGQRRNRFASYSHGFLGQDGVDPARIWAEACRQLLAYPTVTWVEGSAST
IAGGKDEFRVSTAAGDTFAGRRILLATGVADRLPDIPGLADRWGRTVFHCPYCHGYELDQGRIGVIATGAMSLHQAQLLP
EWGEVTFLTNGALTLEPEQRDDLRSRGVAIEETPVARIAGEAEVELRDGRVLPFAGLFTATGTEPASPLAEAAGCELIET
PMGRQIVTDETKETSLPGIFACGDVARAPHSVSLAVGDGAWAGAQLHRSLVWPE

Sequences:

>Translated_294_residues
MQDVIVIGGSYAGMAAALQLARARRKVLVIDAGQRRNRFASYSHGFLGQDGVDPARIWAEACRQLLAYPTVTWVEGSAST
IAGGKDEFRVSTAAGDTFAGRRILLATGVADRLPDIPGLADRWGRTVFHCPYCHGYELDQGRIGVIATGAMSLHQAQLLP
EWGEVTFLTNGALTLEPEQRDDLRSRGVAIEETPVARIAGEAEVELRDGRVLPFAGLFTATGTEPASPLAEAAGCELIET
PMGRQIVTDETKETSLPGIFACGDVARAPHSVSLAVGDGAWAGAQLHRSLVWPE
>Mature_294_residues
MQDVIVIGGSYAGMAAALQLARARRKVLVIDAGQRRNRFASYSHGFLGQDGVDPARIWAEACRQLLAYPTVTWVEGSAST
IAGGKDEFRVSTAAGDTFAGRRILLATGVADRLPDIPGLADRWGRTVFHCPYCHGYELDQGRIGVIATGAMSLHQAQLLP
EWGEVTFLTNGALTLEPEQRDDLRSRGVAIEETPVARIAGEAEVELRDGRVLPFAGLFTATGTEPASPLAEAAGCELIET
PMGRQIVTDETKETSLPGIFACGDVARAPHSVSLAVGDGAWAGAQLHRSLVWPE

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 31362; Mature: 31362

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDVIVIGGSYAGMAAALQLARARRKVLVIDAGQRRNRFASYSHGFLGQDGVDPARIWAE
CCCEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHCCCCCCCCCCCCCHHHHHHH
ACRQLLAYPTVTWVEGSASTIAGGKDEFRVSTAAGDTFAGRRILLATGVADRLPDIPGLA
HHHHHHHCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCHHHCCCCCCHH
DRWGRTVFHCPYCHGYELDQGRIGVIATGAMSLHQAQLLPEWGEVTFLTNGALTLEPEQR
HHHCCEEEECCCCCCEECCCCCEEEEEECCHHHHHHHHCCCCCCEEEEECCEEEECCCHH
DDLRSRGVAIEETPVARIAGEAEVELRDGRVLPFAGLFTATGTEPASPLAEAAGCELIET
HHHHHCCEEEECCCHHHHCCCCEEEEECCEEEEEECEEEECCCCCCCHHHHHHCCEEECC
PMGRQIVTDETKETSLPGIFACGDVARAPHSVSLAVGDGAWAGAQLHRSLVWPE
CCCCEEECCCCCCCCCCCEEEECHHHCCCCEEEEEECCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MQDVIVIGGSYAGMAAALQLARARRKVLVIDAGQRRNRFASYSHGFLGQDGVDPARIWAE
CCCEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHCCCCCCCCCCCCCHHHHHHH
ACRQLLAYPTVTWVEGSASTIAGGKDEFRVSTAAGDTFAGRRILLATGVADRLPDIPGLA
HHHHHHHCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCHHHCCCCCCHH
DRWGRTVFHCPYCHGYELDQGRIGVIATGAMSLHQAQLLPEWGEVTFLTNGALTLEPEQR
HHHCCEEEECCCCCCEECCCCCEEEEEECCHHHHHHHHCCCCCCEEEEECCEEEECCCHH
DDLRSRGVAIEETPVARIAGEAEVELRDGRVLPFAGLFTATGTEPASPLAEAAGCELIET
HHHHHCCEEEECCCHHHHCCCCEEEEECCEEEEEECEEEECCCCCCCHHHHHHCCEEECC
PMGRQIVTDETKETSLPGIFACGDVARAPHSVSLAVGDGAWAGAQLHRSLVWPE
CCCCEEECCCCCCCCCCCEEEECHHHCCCCEEEEEECCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]