Click here to switch to the map view.

The map label for this gene is murG

Identifier: 119358485

GI number: 119358485

Start: 3111023

End: 3112117

Strand: Reverse

Name: murG

Synonym: Cpha266_2721

Alternate gene names: 119358485

Gene position: 3112117-3111023 (Counterclockwise)

Preceding gene: 119358486

Following gene: 119358484

Centisome position: 99.3

GC content: 55.62

Gene sequence:

>1095_bases
ATGAACGTCCTGTTTGCCGGAGGCGGAACCGGAGGCCATCTTTATCCGGCGGTTGCCATGGCGGGCGAACTCCAGAAAAG
GGTTCCCCATGTAAAGCTCTCTTTTGCAGGAACGGAGGCAGGAATCGAGGCCAGAGAAATTCCCCGGCTCGGCTATCGTC
TTCACCTGCTGTCGGTAAGAGGATTGAAGCGCGGCCGCTCTTTGGGGGCGCTTGTTGATAACCTTGGCGTGCTTGCCGAT
TTTATCGGGGCGGTTCGGAGCGCTTTAGCGATTATAAACAGCGAATCCCCCGACGTTGTCGTCGGAACGGGCGGCTTTGT
CAGCGCCCCGCTTCTGCTTGCCGCCCAGATGAGAGGCAAAAAAACGCTGATCCAGGAACAGAATGCGTTTCCCGGCGTAA
CAACAAAGCTGCTCTCTCTTTTTGCCAGCGAGATACATCTCTCTTTCGAAGAGGCGAAACCGTATATTGCAAGAAAAAAA
GAGGTATATATCTCCGGCAATCCATCTCGTTCATTCTCCGCTATCGATCCCGACCAAGCGCGATTGCGCTTCGGTCTCGC
TGAATCACTGCCTACGCTGCTTGTTTTCGGCGGCAGTCGGGGAGCTCGCTCGATCAACAATGCCGTCCTGAAGTGGCTTG
ATCAGATCACCGCATCGGCTAACCTGATCTGGCAGACCGGCAGCCTTGATTACGAAAGGATAAAAGCCGGGGTAACGTCT
TCCGCGAGAATCTGGATAGGCCCGTACATCGAAAATATGGGCGAAGCCTACGCCGCATCGGAACTTGTGGTGTGCAGGGC
CGGGGCCTCCACCATCGCGGAGGTGACCAATACGGCAAAACCCTCGGTGCTGGTTCCCTATCCGCATGCGACAGGAGATC
ATCAGCGCCATAACGCGCGCGCTCTGGCAGAAAACGGCGCAGCCTTGCTTATAGACGACGAGCATCTTCAGGCGCCTGAA
TCACGACAACTTGTTCTCGATCTGCTGCATGACCGGACAAGACGCTCCGCCATGAGCAAGGCCGCTCTTTTGCTTGCTTA
TCCGGATGCGACGGCAGCGCTTGTTGACAGAATCATCCGCCTTGCAAAATCATAA

Upstream 100 bases:

>100_bases
TCAACTCTCTCGGAGTGGGGATTCTTATCAGCATATCGCGACACAAGAAAAGGAACCATCCTGAACGATCATCATCGGAT
GATGAATCGGGAGGCGGCAT

Downstream 100 bases:

>100_bases
AGGAAAAACATGGAGCTCGGAAAAACAAAAAGTGTTCATATCGTAGGAATCGGCGGAGCGGGAATGAGCGCCATTGCCGA
ACTTCTGTTAACCTCGGGTT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MNVLFAGGGTGGHLYPAVAMAGELQKRVPHVKLSFAGTEAGIEAREIPRLGYRLHLLSVRGLKRGRSLGALVDNLGVLAD
FIGAVRSALAIINSESPDVVVGTGGFVSAPLLLAAQMRGKKTLIQEQNAFPGVTTKLLSLFASEIHLSFEEAKPYIARKK
EVYISGNPSRSFSAIDPDQARLRFGLAESLPTLLVFGGSRGARSINNAVLKWLDQITASANLIWQTGSLDYERIKAGVTS
SARIWIGPYIENMGEAYAASELVVCRAGASTIAEVTNTAKPSVLVPYPHATGDHQRHNARALAENGAALLIDDEHLQAPE
SRQLVLDLLHDRTRRSAMSKAALLLAYPDATAALVDRIIRLAKS

Sequences:

>Translated_364_residues
MNVLFAGGGTGGHLYPAVAMAGELQKRVPHVKLSFAGTEAGIEAREIPRLGYRLHLLSVRGLKRGRSLGALVDNLGVLAD
FIGAVRSALAIINSESPDVVVGTGGFVSAPLLLAAQMRGKKTLIQEQNAFPGVTTKLLSLFASEIHLSFEEAKPYIARKK
EVYISGNPSRSFSAIDPDQARLRFGLAESLPTLLVFGGSRGARSINNAVLKWLDQITASANLIWQTGSLDYERIKAGVTS
SARIWIGPYIENMGEAYAASELVVCRAGASTIAEVTNTAKPSVLVPYPHATGDHQRHNARALAENGAALLIDDEHLQAPE
SRQLVLDLLHDRTRRSAMSKAALLLAYPDATAALVDRIIRLAKS
>Mature_364_residues
MNVLFAGGGTGGHLYPAVAMAGELQKRVPHVKLSFAGTEAGIEAREIPRLGYRLHLLSVRGLKRGRSLGALVDNLGVLAD
FIGAVRSALAIINSESPDVVVGTGGFVSAPLLLAAQMRGKKTLIQEQNAFPGVTTKLLSLFASEIHLSFEEAKPYIARKK
EVYISGNPSRSFSAIDPDQARLRFGLAESLPTLLVFGGSRGARSINNAVLKWLDQITASANLIWQTGSLDYERIKAGVTS
SARIWIGPYIENMGEAYAASELVVCRAGASTIAEVTNTAKPSVLVPYPHATGDHQRHNARALAENGAALLIDDEHLQAPE
SRQLVLDLLHDRTRRSAMSKAALLLAYPDATAALVDRIIRLAKS

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=369, Percent_Identity=30.3523035230352, Blast_Score=145, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_CHLPD (A1BJX8)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_913129.1
- ProteinModelPortal:   A1BJX8
- SMR:   A1BJX8
- STRING:   A1BJX8
- GeneID:   4570695
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2721
- NMPDR:   fig|290317.7.peg.2842
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38974; Mature: 38974

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLFAGGGTGGHLYPAVAMAGELQKRVPHVKLSFAGTEAGIEAREIPRLGYRLHLLSVR
CEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHCCCCCEEEEEEEHH
GLKRGRSLGALVDNLGVLADFIGAVRSALAIINSESPDVVVGTGGFVSAPLLLAAQMRGK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCC
KTLIQEQNAFPGVTTKLLSLFASEIHLSFEEAKPYIARKKEVYISGNPSRSFSAIDPDQA
HHHHHCCCCCCCHHHHHHHHHHHHHHEEHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHH
RLRFGLAESLPTLLVFGGSRGARSINNAVLKWLDQITASANLIWQTGSLDYERIKAGVTS
HHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCC
SARIWIGPYIENMGEAYAASELVVCRAGASTIAEVTNTAKPSVLVPYPHATGDHQRHNAR
CCEEEECHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCEEEECCCCCCCCCHHHHH
ALAENGAALLIDDEHLQAPESRQLVLDLLHDRTRRSAMSKAALLLAYPDATAALVDRIIR
HHHCCCCEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHH
LAKS
HHCC
>Mature Secondary Structure
MNVLFAGGGTGGHLYPAVAMAGELQKRVPHVKLSFAGTEAGIEAREIPRLGYRLHLLSVR
CEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHCCCCCEEEEEEEHH
GLKRGRSLGALVDNLGVLADFIGAVRSALAIINSESPDVVVGTGGFVSAPLLLAAQMRGK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCC
KTLIQEQNAFPGVTTKLLSLFASEIHLSFEEAKPYIARKKEVYISGNPSRSFSAIDPDQA
HHHHHCCCCCCCHHHHHHHHHHHHHHEEHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHH
RLRFGLAESLPTLLVFGGSRGARSINNAVLKWLDQITASANLIWQTGSLDYERIKAGVTS
HHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCC
SARIWIGPYIENMGEAYAASELVVCRAGASTIAEVTNTAKPSVLVPYPHATGDHQRHNAR
CCEEEECHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCEEEECCCCCCCCCHHHHH
ALAENGAALLIDDEHLQAPESRQLVLDLLHDRTRRSAMSKAALLLAYPDATAALVDRIIR
HHHCCCCEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHH
LAKS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA