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The map label for this gene is atpB

Identifier: 119358473

GI number: 119358473

Start: 3099791

End: 3100819

Strand: Reverse

Name: atpB

Synonym: Cpha266_2709

Alternate gene names: 119358473

Gene position: 3100819-3099791 (Counterclockwise)

Preceding gene: 119358474

Following gene: 119358472

Centisome position: 98.94

GC content: 50.34

Gene sequence:

>1029_bases
ATGAAACAGGAACGCACCAGTAAAGTCAAGGGATTGATAAAGGTTATAGCACTTGTAGTGCCTTTTCTCCTCAACGTCAA
TGCGTTCGCTTCTCCGGCAGAAAGCGCGGGAGTGACTCATGATTCGATCGCTGCGGTTGCCCGTACCGAGGGAGCTCACG
CCGGGGAGGCTCCGCACGGCGAGGCGGCAGGTCACGGCGAAGAGAAGGCCGGCGACGTCATCATGCACCATATTCTTGAC
AGCAACGTCTACTCCTTTGAACCCTTTGGCGAGATCGTGCTCCCGAAAATCGTCGTAGGCGGATTTGATATCTCCATAAC
GAAACATGTCGTTACGCTCTGGGTCGTTTCGGCGATCGTGCTGATAGTCTTCACGATAATCGGCAGCAAGTACAAAACCA
TGTCTCCGAAGACTGCTCCCAAGGGTTTTGTCAACGCGATGGAGGCTCTGGTTGAGTTTATAAGGCTTGATGTAGCAAAA
GCCAATATCGGGCCAGGATATGAAAAATATCTCCCCTATCTGCTGACGGTATTCATGTTTGTTCTTCTCTGTAACGTCCT
CGGGCTTGTTCCTTACGGGGCGACGGCGACAGGCAACATTAACGTCACGCTGACCCTTGCAACATTTACCTTCGTCCTTA
CCCAGATAGCAGCATTGAAAGCCCATGGCATAAAAGGCTATCTTGCGCACCTGACGGGAGGTACTCACCCTGCGCTCTGG
ATCATCATGATTCCCATCGAGTTCATCGGTCTGTTTACCAAGCCGGTTGCGCTGACGATCCGGTTATTTGCCAACATGAC
CGCCGGGCACATCGTGATTCTCAGTTTGATTTTTATCAGCTTTATTCTCAAGAGTTATATCGTGGCGGTTGCCATGTCTG
TCCCGTTCTCTATATTTATTTATCTGCTTGAGATATTTGTAGCCTTCCTTCAGGCCTATATTTTCACGATGCTTTCGGCA
CTCTTTATCGGTCTTGCTTCAGCACATGAGGAGCATGCCGATCACGAAGCCGGAGCTGCACATCATTGA

Upstream 100 bases:

>100_bases
TGAACGATTTTGTGCTTTCGTTTTTCGCTTTTTACTGTATTTATGTGATTGTTGAAATACTCGCTTATCAAAAGAAAAAC
AAACAGAAAAAGAACGTTGC

Downstream 100 bases:

>100_bases
ATCCCTGATAGGTCATGTCAGAATATCGAGGGTGAGAAAAGAGCTGATTTTGTAACTGCTGATTAATTTTTTTGAATAAC
ATCTTACAACAAATAAACGG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKQERTSKVKGLIKVIALVVPFLLNVNAFASPAESAGVTHDSIAAVARTEGAHAGEAPHGEAAGHGEEKAGDVIMHHILD
SNVYSFEPFGEIVLPKIVVGGFDISITKHVVTLWVVSAIVLIVFTIIGSKYKTMSPKTAPKGFVNAMEALVEFIRLDVAK
ANIGPGYEKYLPYLLTVFMFVLLCNVLGLVPYGATATGNINVTLTLATFTFVLTQIAALKAHGIKGYLAHLTGGTHPALW
IIMIPIEFIGLFTKPVALTIRLFANMTAGHIVILSLIFISFILKSYIVAVAMSVPFSIFIYLLEIFVAFLQAYIFTMLSA
LFIGLASAHEEHADHEAGAAHH

Sequences:

>Translated_342_residues
MKQERTSKVKGLIKVIALVVPFLLNVNAFASPAESAGVTHDSIAAVARTEGAHAGEAPHGEAAGHGEEKAGDVIMHHILD
SNVYSFEPFGEIVLPKIVVGGFDISITKHVVTLWVVSAIVLIVFTIIGSKYKTMSPKTAPKGFVNAMEALVEFIRLDVAK
ANIGPGYEKYLPYLLTVFMFVLLCNVLGLVPYGATATGNINVTLTLATFTFVLTQIAALKAHGIKGYLAHLTGGTHPALW
IIMIPIEFIGLFTKPVALTIRLFANMTAGHIVILSLIFISFILKSYIVAVAMSVPFSIFIYLLEIFVAFLQAYIFTMLSA
LFIGLASAHEEHADHEAGAAHH
>Mature_342_residues
MKQERTSKVKGLIKVIALVVPFLLNVNAFASPAESAGVTHDSIAAVARTEGAHAGEAPHGEAAGHGEEKAGDVIMHHILD
SNVYSFEPFGEIVLPKIVVGGFDISITKHVVTLWVVSAIVLIVFTIIGSKYKTMSPKTAPKGFVNAMEALVEFIRLDVAK
ANIGPGYEKYLPYLLTVFMFVLLCNVLGLVPYGATATGNINVTLTLATFTFVLTQIAALKAHGIKGYLAHLTGGTHPALW
IIMIPIEFIGLFTKPVALTIRLFANMTAGHIVILSLIFISFILKSYIVAVAMSVPFSIFIYLLEIFVAFLQAYIFTMLSA
LFIGLASAHEEHADHEAGAAHH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=212, Percent_Identity=30.188679245283, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_CHLPD (A1BJW6)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_913117.1
- ProteinModelPortal:   A1BJW6
- SMR:   A1BJW6
- STRING:   A1BJW6
- GeneID:   4570683
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2709
- NMPDR:   fig|290317.7.peg.2829
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   DISITKH
- ProtClustDB:   PRK13419
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 36825; Mature: 36825

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x135ed11c)-; HASH(0x1385dc44)-; HASH(0x12e54708)-; HASH(0x12440d74)-; HASH(0x138323e8)-; HASH(0x12b58e38)-; HASH(0x12440be8)-; HASH(0x1307cf30)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQERTSKVKGLIKVIALVVPFLLNVNAFASPAESAGVTHDSIAAVARTEGAHAGEAPHG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCC
EAAGHGEEKAGDVIMHHILDSNVYSFEPFGEIVLPKIVVGGFDISITKHVVTLWVVSAIV
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LIVFTIIGSKYKTMSPKTAPKGFVNAMEALVEFIRLDVAKANIGPGYEKYLPYLLTVFMF
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VLLCNVLGLVPYGATATGNINVTLTLATFTFVLTQIAALKAHGIKGYLAHLTGGTHPALW
HHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHE
IIMIPIEFIGLFTKPVALTIRLFANMTAGHIVILSLIFISFILKSYIVAVAMSVPFSIFI
EEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLLEIFVAFLQAYIFTMLSALFIGLASAHEEHADHEAGAAHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure
MKQERTSKVKGLIKVIALVVPFLLNVNAFASPAESAGVTHDSIAAVARTEGAHAGEAPHG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCC
EAAGHGEEKAGDVIMHHILDSNVYSFEPFGEIVLPKIVVGGFDISITKHVVTLWVVSAIV
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LIVFTIIGSKYKTMSPKTAPKGFVNAMEALVEFIRLDVAKANIGPGYEKYLPYLLTVFMF
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VLLCNVLGLVPYGATATGNINVTLTLATFTFVLTQIAALKAHGIKGYLAHLTGGTHPALW
HHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHE
IIMIPIEFIGLFTKPVALTIRLFANMTAGHIVILSLIFISFILKSYIVAVAMSVPFSIFI
EEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLLEIFVAFLQAYIFTMLSALFIGLASAHEEHADHEAGAAHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA