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The map label for this gene is trpS [H]

Identifier: 119358464

GI number: 119358464

Start: 3092497

End: 3093519

Strand: Direct

Name: trpS [H]

Synonym: Cpha266_2700

Alternate gene names: 119358464

Gene position: 3092497-3093519 (Clockwise)

Preceding gene: 119358461

Following gene: 119358465

Centisome position: 98.68

GC content: 49.46

Gene sequence:

>1023_bases
ATGGCAATACAGCGCATTTTAAGCGGGATGCGTCCTACCGGAAAGCTGCATCTCGGTCATTTTACCGGCGCTCTTGAAAA
CTGGGTCGAGCAACAGAACCTTATGAGAGAGGATGGGTCGCGGGTTTATGAAACCTGTTTTCTTATTGCCGATTATCACA
GCCTCACGACTTCGCTCGATACCGGCGATCTGTATGCAAACTCTCTCGATATGCTCATCGACTGGCTTTCGGCAGGCGTT
GATCCGGAAAAAAGCCCTGTCTTCCGGCAATCGAGAATCAAGGAACATGCCGAACTCTTCCTTCTTTTTTCAATGCTTGT
CACGGCGTCGCGTCTGGAACGAAATCCAACCCTGAAAGAACAGGTTCGTGACCTTAATCTTGAGTCCCTGGTTTACGGCC
ATCTCGGCTATCCCGTTCTGCAGGCAGCCGATATCCTGCTGTATAAGGGAACGGTCGTGCCTGTCGGCGAGGACCAGATC
CCCCATGTTGAAATAACAAGAGAGATCGCCCGTAAATTTAATAACCATTACCCTCATCCGTTAAACGGCGTGGTGTTTAT
GGAGCCTGAGCCTAAAATAACCAAATTCTCACGGCTTGTCGGTCTTGACGGGAAGTCTAAAATGTCGAAATCTCTCGGCA
ACACCATCCTTCTTTCCGACGGAAGCGAGGAGGTATTCAAAAAAGTCCGCAATGCTGTCACCGATACCGAGAAAATCCGA
AAGAACGACCCCGGAAGACCTGAGGTCTGTACGGTTTTCAGCTATCATGGCAAATTTACTCCGCAAATGCAACGAGACAT
CATCGAAATGGACTGCCGTTCCGGTAGCCTCGGTTGCGTTGACTGTAAAAAAATCTGCGCGGCAAATATTTCGCATGCGC
TTCTGCCCCTTGTTGAAAAACGACGCTATTATGAAGCGCATATCGATCTGGTTACGGAAATTCTTTATGAGGGCGAACGC
AAGGCGCAGGCAATAGCCCGAAATACGATGGAAGAGGTCAGAGAGGCCATGAGGCTTGGTTGA

Upstream 100 bases:

>100_bases
CTGTTATAACTTCCTCTGCATTTATCAGTGGAACCCGCCACATTCATAGCCTGCCTGTGGCTGTTTATACGCCTTCAGCG
AGAACCGATACTATTATTCT

Downstream 100 bases:

>100_bases
ATAGAGTCGATTGAAGCACTATTGCACAAGAGGAGAGCAGTGAAAGAGCATAACCGATACGCGTTTATTTTTGACATGGA
TGGCGTCCTGACTGACAACA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MAIQRILSGMRPTGKLHLGHFTGALENWVEQQNLMREDGSRVYETCFLIADYHSLTTSLDTGDLYANSLDMLIDWLSAGV
DPEKSPVFRQSRIKEHAELFLLFSMLVTASRLERNPTLKEQVRDLNLESLVYGHLGYPVLQAADILLYKGTVVPVGEDQI
PHVEITREIARKFNNHYPHPLNGVVFMEPEPKITKFSRLVGLDGKSKMSKSLGNTILLSDGSEEVFKKVRNAVTDTEKIR
KNDPGRPEVCTVFSYHGKFTPQMQRDIIEMDCRSGSLGCVDCKKICAANISHALLPLVEKRRYYEAHIDLVTEILYEGER
KAQAIARNTMEEVREAMRLG

Sequences:

>Translated_340_residues
MAIQRILSGMRPTGKLHLGHFTGALENWVEQQNLMREDGSRVYETCFLIADYHSLTTSLDTGDLYANSLDMLIDWLSAGV
DPEKSPVFRQSRIKEHAELFLLFSMLVTASRLERNPTLKEQVRDLNLESLVYGHLGYPVLQAADILLYKGTVVPVGEDQI
PHVEITREIARKFNNHYPHPLNGVVFMEPEPKITKFSRLVGLDGKSKMSKSLGNTILLSDGSEEVFKKVRNAVTDTEKIR
KNDPGRPEVCTVFSYHGKFTPQMQRDIIEMDCRSGSLGCVDCKKICAANISHALLPLVEKRRYYEAHIDLVTEILYEGER
KAQAIARNTMEEVREAMRLG
>Mature_339_residues
AIQRILSGMRPTGKLHLGHFTGALENWVEQQNLMREDGSRVYETCFLIADYHSLTTSLDTGDLYANSLDMLIDWLSAGVD
PEKSPVFRQSRIKEHAELFLLFSMLVTASRLERNPTLKEQVRDLNLESLVYGHLGYPVLQAADILLYKGTVVPVGEDQIP
HVEITREIARKFNNHYPHPLNGVVFMEPEPKITKFSRLVGLDGKSKMSKSLGNTILLSDGSEEVFKKVRNAVTDTEKIRK
NDPGRPEVCTVFSYHGKFTPQMQRDIIEMDCRSGSLGCVDCKKICAANISHALLPLVEKRRYYEAHIDLVTEILYEGERK
AQAIARNTMEEVREAMRLG

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=340, Percent_Identity=35.2941176470588, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI41352700, Length=187, Percent_Identity=42.7807486631016, Blast_Score=138, Evalue=9e-33,
Organism=Escherichia coli, GI1789786, Length=340, Percent_Identity=33.2352941176471, Blast_Score=155, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71982800, Length=339, Percent_Identity=29.4985250737463, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71982793, Length=339, Percent_Identity=29.4985250737463, Blast_Score=127, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6320474, Length=354, Percent_Identity=31.638418079096, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24666151, Length=344, Percent_Identity=34.0116279069767, Blast_Score=169, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 38523; Mature: 38392

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00178 AA_TRNA_LIGASE_I ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQRILSGMRPTGKLHLGHFTGALENWVEQQNLMREDGSRVYETCFLIADYHSLTTSLD
CCHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
TGDLYANSLDMLIDWLSAGVDPEKSPVFRQSRIKEHAELFLLFSMLVTASRLERNPTLKE
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QVRDLNLESLVYGHLGYPVLQAADILLYKGTVVPVGEDQIPHVEITREIARKFNNHYPHP
HHHHCCHHHHHHHHCCCHHHHHHHHHEECCEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
LNGVVFMEPEPKITKFSRLVGLDGKSKMSKSLGNTILLSDGSEEVFKKVRNAVTDTEKIR
CCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHH
KNDPGRPEVCTVFSYHGKFTPQMQRDIIEMDCRSGSLGCVDCKKICAANISHALLPLVEK
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRYYEAHIDLVTEILYEGERKAQAIARNTMEEVREAMRLG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIQRILSGMRPTGKLHLGHFTGALENWVEQQNLMREDGSRVYETCFLIADYHSLTTSLD
CHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
TGDLYANSLDMLIDWLSAGVDPEKSPVFRQSRIKEHAELFLLFSMLVTASRLERNPTLKE
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QVRDLNLESLVYGHLGYPVLQAADILLYKGTVVPVGEDQIPHVEITREIARKFNNHYPHP
HHHHCCHHHHHHHHCCCHHHHHHHHHEECCEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
LNGVVFMEPEPKITKFSRLVGLDGKSKMSKSLGNTILLSDGSEEVFKKVRNAVTDTEKIR
CCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHH
KNDPGRPEVCTVFSYHGKFTPQMQRDIIEMDCRSGSLGCVDCKKICAANISHALLPLVEK
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRYYEAHIDLVTEILYEGERKAQAIARNTMEEVREAMRLG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]