Click here to switch to the map view.

The map label for this gene is prmA [H]

Identifier: 119358353

GI number: 119358353

Start: 2959954

End: 2960823

Strand: Direct

Name: prmA [H]

Synonym: Cpha266_2585

Alternate gene names: 119358353

Gene position: 2959954-2960823 (Clockwise)

Preceding gene: 119358352

Following gene: 119358354

Centisome position: 94.45

GC content: 52.53

Gene sequence:

>870_bases
ATGCCGACCACCGGAACACACCACTACATCGAACTGGCAATTGAACTCAACCCATCCCTCTTCGAACTCGCCATCGCCAT
GCTCTCCAGAGAGGGCATCGACTCATTCATGGAAGAGGAAACCCGACTCCTGGCCTACCTCCCCGAATCGGAATGGAACG
AAAAAAAAGAATTGTCAATTCGTCAAACGCTTGAACAAACGTTCGGCACCATCCCTCCCTGCACGGCCAGCTTCATGGCC
GACAGAAACTGGAATGCCGAATGGGAAGCACACCTCCAGCCCATCGAAATCTCCGACCGCATCATCATTATTCAGAAAAA
CAAGGAGATAACGCCAAAACCCGGCCAGATCGTTATCGAAATCAACCCGAAAATGTCCTTCGGCACCGGCTACCACGCAA
CCACGCGGCTGATGCTCCGGCAGATGGAAACCCTTGACCTCGTCAACAAAAAAATCATGGACATAGGCACCGGCACCGGC
GTTCTGGCCATCGCCGCCCGCAAACTCGGAAACAACCTCCCGATCCTTGCGTTCGACAACAACGCCTGGGCAACCGACAA
CGCCATTGAAAACGTCGAAGAAAACCATGCCGACAATATCGCCGTCGAACTCCTCGATGCCGAAGAAGATCTCGTCATAC
ACCTCGGCGAAGGGTATGACCTGATTCTGGCCAACATCAATAAAAACGTGATCGACCGAATCCTGCCGATAATCAGAAAA
CATGCTCCCCAAGCCCCGGTACTCCTCTCGGGCATACTGATCTATGACGAACCGTGGCTGAAAAAACTCCTGAAAAAACT
CAACTACCAGATCGAAAAAACCATCTACGAAGACGAATGGCTCTCCAGCCTTGTCCGCCCGACGCCATGA

Upstream 100 bases:

>100_bases
CAAAAGAACACGATCTTTCTTTGGCTCCTGAAATCCTATATTACAACCAAACACACACCGATCAAAACTCATAACTATCT
CAGATAAGGCTTCCACACCT

Downstream 100 bases:

>100_bases
AACGAATCTCATGCATAGACATCGGCACCAACACAGCACTCCTGCTCATTGCCGATCTCGACCCGAAAACCGGACAAATC
ATACCGGTCTGTCACAAACA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MPTTGTHHYIELAIELNPSLFELAIAMLSREGIDSFMEEETRLLAYLPESEWNEKKELSIRQTLEQTFGTIPPCTASFMA
DRNWNAEWEAHLQPIEISDRIIIIQKNKEITPKPGQIVIEINPKMSFGTGYHATTRLMLRQMETLDLVNKKIMDIGTGTG
VLAIAARKLGNNLPILAFDNNAWATDNAIENVEENHADNIAVELLDAEEDLVIHLGEGYDLILANINKNVIDRILPIIRK
HAPQAPVLLSGILIYDEPWLKKLLKKLNYQIEKTIYEDEWLSSLVRPTP

Sequences:

>Translated_289_residues
MPTTGTHHYIELAIELNPSLFELAIAMLSREGIDSFMEEETRLLAYLPESEWNEKKELSIRQTLEQTFGTIPPCTASFMA
DRNWNAEWEAHLQPIEISDRIIIIQKNKEITPKPGQIVIEINPKMSFGTGYHATTRLMLRQMETLDLVNKKIMDIGTGTG
VLAIAARKLGNNLPILAFDNNAWATDNAIENVEENHADNIAVELLDAEEDLVIHLGEGYDLILANINKNVIDRILPIIRK
HAPQAPVLLSGILIYDEPWLKKLLKKLNYQIEKTIYEDEWLSSLVRPTP
>Mature_288_residues
PTTGTHHYIELAIELNPSLFELAIAMLSREGIDSFMEEETRLLAYLPESEWNEKKELSIRQTLEQTFGTIPPCTASFMAD
RNWNAEWEAHLQPIEISDRIIIIQKNKEITPKPGQIVIEINPKMSFGTGYHATTRLMLRQMETLDLVNKKIMDIGTGTGV
LAIAARKLGNNLPILAFDNNAWATDNAIENVEENHADNIAVELLDAEEDLVIHLGEGYDLILANINKNVIDRILPIIRKH
APQAPVLLSGILIYDEPWLKKLLKKLNYQIEKTIYEDEWLSSLVRPTP

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=87, Percent_Identity=34.4827586206897, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32815; Mature: 32684

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTTGTHHYIELAIELNPSLFELAIAMLSREGIDSFMEEETRLLAYLPESEWNEKKELSI
CCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHH
RQTLEQTFGTIPPCTASFMADRNWNAEWEAHLQPIEISDRIIIIQKNKEITPKPGQIVIE
HHHHHHHHCCCCCCHHHHHHCCCCCCCHHHCCCEEEECCEEEEEECCCCCCCCCCEEEEE
INPKMSFGTGYHATTRLMLRQMETLDLVNKKIMDIGTGTGVLAIAARKLGNNLPILAFDN
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECC
NAWATDNAIENVEENHADNIAVELLDAEEDLVIHLGEGYDLILANINKNVIDRILPIIRK
CCCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHH
HAPQAPVLLSGILIYDEPWLKKLLKKLNYQIEKTIYEDEWLSSLVRPTP
CCCCCCHHHCCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PTTGTHHYIELAIELNPSLFELAIAMLSREGIDSFMEEETRLLAYLPESEWNEKKELSI
CCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHH
RQTLEQTFGTIPPCTASFMADRNWNAEWEAHLQPIEISDRIIIIQKNKEITPKPGQIVIE
HHHHHHHHCCCCCCHHHHHHCCCCCCCHHHCCCEEEECCEEEEEECCCCCCCCCCEEEEE
INPKMSFGTGYHATTRLMLRQMETLDLVNKKIMDIGTGTGVLAIAARKLGNNLPILAFDN
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECC
NAWATDNAIENVEENHADNIAVELLDAEEDLVIHLGEGYDLILANINKNVIDRILPIIRK
CCCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHH
HAPQAPVLLSGILIYDEPWLKKLLKKLNYQIEKTIYEDEWLSSLVRPTP
CCCCCCHHHCCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA