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The map label for this gene is kdsC [H]

Identifier: 119358343

GI number: 119358343

Start: 2950339

End: 2950884

Strand: Reverse

Name: kdsC [H]

Synonym: Cpha266_2575

Alternate gene names: 119358343

Gene position: 2950884-2950339 (Counterclockwise)

Preceding gene: 119358344

Following gene: 119358337

Centisome position: 94.16

GC content: 54.76

Gene sequence:

>546_bases
ATGCAGCCCTCCGAGGCGGATCCCTCTTCCAGGATTCAGCAGGCGCTTGCTGCAGTAAGGGCGCTGGTTATTCCAGTGGA
CGGCGTGCTCAATGGCGGCAGGATGACAATTGACGGCAGCGGTCGGGAGATCTGTTCGATCTCTCTGAGGGATGCAACGG
CTTTGAAAGAGGCTTTGAAACAGGGGTTGATTGTGGCGGTGGTTTCGGAGCGCGATGCCGAGGCGTATCGGCCTCTTCTT
GAGCAGCTCGGCGTTACTTCGCTTTATCTCAATGCGGAAAGCGTTTTTGATGCCTATGTCGCTTTTCGGGATTCTGCTGG
CCTCGATGATGATTCGTGTGCCTATATCGGCGATGATCTTGGCGATATATCGGTGCTCGAGCAGGTCGGGTTTCCTGTGA
CTCCTATTGACGGCACCGACTATCTTCGCCATCGTGTTGCCTATATCTCAGCCTATGAGGGCGGCAAGGGGTGTGTGCGG
GAGATCGTTGAGATGATTTTGATGCAGCAGGGCAAGTGGTCGTATATGGATCATCGCGAAGCTTAG

Upstream 100 bases:

>100_bases
CTTCTGTTGTTAAAGAGCTGATGCAGCTTTGTCGCTGTATGCAGTCTATTCATTCACTATAAAACGGGTTACGCTCTTGT
CAGGTTTTCAGTTTTTCGGG

Downstream 100 bases:

>100_bases
GTTTTTCGGTGCCTTTTGGTCGTTTGTCCGGCGTTTTTCACTTTTGCAGGGGCGGGGTGCGCGGATTCGGGGCGTTCTGG
TATTGGCGGAGAATTCGGGC

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MQPSEADPSSRIQQALAAVRALVIPVDGVLNGGRMTIDGSGREICSISLRDATALKEALKQGLIVAVVSERDAEAYRPLL
EQLGVTSLYLNAESVFDAYVAFRDSAGLDDDSCAYIGDDLGDISVLEQVGFPVTPIDGTDYLRHRVAYISAYEGGKGCVR
EIVEMILMQQGKWSYMDHREA

Sequences:

>Translated_181_residues
MQPSEADPSSRIQQALAAVRALVIPVDGVLNGGRMTIDGSGREICSISLRDATALKEALKQGLIVAVVSERDAEAYRPLL
EQLGVTSLYLNAESVFDAYVAFRDSAGLDDDSCAYIGDDLGDISVLEQVGFPVTPIDGTDYLRHRVAYISAYEGGKGCVR
EIVEMILMQQGKWSYMDHREA
>Mature_181_residues
MQPSEADPSSRIQQALAAVRALVIPVDGVLNGGRMTIDGSGREICSISLRDATALKEALKQGLIVAVVSERDAEAYRPLL
EQLGVTSLYLNAESVFDAYVAFRDSAGLDDDSCAYIGDDLGDISVLEQVGFPVTPIDGTDYLRHRVAYISAYEGGKGCVR
EIVEMILMQQGKWSYMDHREA

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=162, Percent_Identity=29.0123456790123, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI2367202, Length=170, Percent_Identity=31.1764705882353, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19660; Mature: 19660

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSEADPSSRIQQALAAVRALVIPVDGVLNGGRMTIDGSGREICSISLRDATALKEALK
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCEEEECCCCCEEEEEECHHHHHHHHHHH
QGLIVAVVSERDAEAYRPLLEQLGVTSLYLNAESVFDAYVAFRDSAGLDDDSCAYIGDDL
CCEEEEEECCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCEECCCCC
GDISVLEQVGFPVTPIDGTDYLRHRVAYISAYEGGKGCVREIVEMILMQQGKWSYMDHRE
CHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
A
C
>Mature Secondary Structure
MQPSEADPSSRIQQALAAVRALVIPVDGVLNGGRMTIDGSGREICSISLRDATALKEALK
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCEEEECCCCCEEEEEECHHHHHHHHHHH
QGLIVAVVSERDAEAYRPLLEQLGVTSLYLNAESVFDAYVAFRDSAGLDDDSCAYIGDDL
CCEEEEEECCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCEECCCCC
GDISVLEQVGFPVTPIDGTDYLRHRVAYISAYEGGKGCVREIVEMILMQQGKWSYMDHRE
CHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]