| Definition | Chlorobium phaeobacteroides DSM 266 chromosome, complete genome. |
|---|---|
| Accession | NC_008639 |
| Length | 3,133,902 |
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The map label for this gene is thrA [H]
Identifier: 119358310
GI number: 119358310
Start: 2917715
End: 2920162
Strand: Reverse
Name: thrA [H]
Synonym: Cpha266_2542
Alternate gene names: 119358310
Gene position: 2920162-2917715 (Counterclockwise)
Preceding gene: 119358311
Following gene: 119358309
Centisome position: 93.18
GC content: 51.14
Gene sequence:
>2448_bases ATGAAGATTTACAAGTTTGGTGGAAGTTCGCTGGGTTCGGCTGCAAGGATCAGAAAGGTTGCAGCAATCATTGCTGGTGC ACGCAGTGAGGGCCCGCTGGTCGTCGTGGTTTCGGCATTGTTCAGGTGTACCGATATGCTTCTCGAATCGGCTAACGAGG CTTGTCTTGGCGATGAAAACTACCGAAAAACGTTTGAGGAGTTCGATGCTCTGCATAGGAATATTGCTGCCGATCTTTTT AACGCTGAGGTTTGCAGCGATGTTGTTTCAGCAATGAGCGATGAACTTCTTGAGTTGAGCGATCTTCTGCATGGCGTTTT TTTGCTCAGGGAGCTTTCTGAAAAAAGCACTGCGCTTATTCTCAGTTTCGGAGAAAGGTTGTCGGCCAGGCTTATCAGTC GTTTTCTTCCTGATGGCTACTATGTTGACGGACGGAATCTGGTCGTTACAGATTCCAACCCTCTTTGCGCAAGGGTTGAC AGGCATGCTACCGAAAAGAGGATTCAGTCCGCATTGTCGTCATGCAGCGGCGTTCCTGTGGTTACCGGGTATATTGCCGC AGCGCCGGACGGGACAGTGACTACGCTTGGCAGAGGGGGATCGGATTATACGGCTTCGCTTGTCGGAGCATCGCTTTCTG CCAGCGAAATCGTGATATGGACCGACGTTGATGGTTTTTACAGTGCTGATCCGAAACGGGTGCGCGATGCCCGGGTGCTT CCGTATATCAGCTATGCGGAGGCTATGGAGCTTTCGCATGCTGGGGCAAAAATTCTTCATCCCTTTTCCATTCAGCCTGC GATGAAAGCGAGCATTCCTGTGCTCATCCGCAATTCATTCAACCCTGACGCGCCTGGTACGAGAATAGAGCGGGATGTGC AGCAGGAGATGAAGGATCGTTTGCCTGTAACGGGGTTGAGCTCGATCAATAAGGTTGTGCTGCTGAATCTTGCCGGAAGC GGTATGGTTGGCGTTCCTGGTATCGCTTCAAGGTTGTTCAGTTGTCTGGCGCTGCATGGGATCAATATCATTTTTATTTC GCAGGCTTCTTCAGAGCAGTCTATCAGTCTTGCCATTAATCCGCTGCAGGCGGAAAAGGCTAAAAAAATTCTTGAGGCCG AGTTCCATTCGGAAATCGAGTCGCGTCTTATTGATCCGCTTTTGATCAGAAGAAGTCTGGCGCTGATTGCTGTGGTTGGG AACAATATGTCGGGGCATCCCGGGGTTTCAGCCCAGCTTTTCGAAACGCTGGGTAAAAACGGAATCAATGTTATTGCCGT GGCGCAGGGTGCAAACGAGATGAATATCTCGCTGGTGATCGAAAGCCATGATGAAGACAAGGCGTTAAACTGCATTCATG AGTCGTTTTTTCTTTCGCAGCGAAAAGTACATGTTTTTCTTGCCGGTACGGGAACGATCGCCAAAAGCCTGTTGCAGCAG ATCAGCGGTCACAGGATGAATCTCAGAGAGGAGAAGGATCTGGATGTGGTTGTTTGCGGTATCGCCAATACAAGAATGAT CGCGCTGAATAACGACGGTATCGATCTGGAGCGCTGGCAGGAGGAGCTTCGTCCGAGAGCCGATGATGCCGGTATCGAGG ACTATATCCGGCTTTTGCAGGAAAGAAATCTTCACAACACTATTTTTGTCGATTGCACGGCGAGCGCAAAGGTGGCGGAA CGCTATCCCGAGCTGCTCAAGGCGAATATTTCTGTCGTTACGGCCAACAAGCTTGGTATGGCCGGTCCCGAAACGCTTTA TCGGGAGATTGTCGATGCCGAGCGGGCAAGCAACGCGAGGTTTCTTTACGAAACCAATGTCGGCGCAGGTCTGCCGATCA TCAATACGTTGAACGATCTGAAAAACAGCGGCGACAAGATTATCAGTATTGAGGGGGTTCTTTCAGGAACCTTGAGCTTT ATTTTTAACGAGTTGCGCAGCGGAGGCACTTTCAGCGAGATTGTCAGAAGGGCGAAAGAGGCCGGCTATACCGAGCCTGA TCCGAGAGACGATCTTTCCGGCGCAGATTTTGCCCGCAAGTTTCTCATTCTTGGTCGTGAGCTCGGATTTTCTCTTGAGT ATGCCGATGTGGTTTGCGAAAGTCTTGTTCCTGTGGATTGCAGGGGCGAGATGTCTGCTGAGGAGTTTCTTGTTCGGTTG CGTTCCGTGGATGATTTTTACGCTGAAGAGATTCGACGGGCAGCTCTTGAGCAGATGACTATTGCGTATGCCGGGGAGAT CAGAAACGGCAAGGCGAGCATTGGCGTCAAGCGGGTGCCGCTGGAAAGTCCGATTGCCGGTCTGAGCGGTTCAGAGAATA TGGTGGTGTTTACCACCGAGCGATATCGAGCGACTCCGCTTGTCGTCAGGGGGCCGGGAGCCGGAGCTGAAGTGACTGCT GGCGGCGTGTTTGCCGATATTCTTCGCATTGCAAGTTATCTGGTTTAA
Upstream 100 bases:
>100_bases TGGAGAACCCTGTACAGGAAATGGTTTTTATTTTATAAGTTTAGGGGGTGCGTCGGGTTCCGTTGTTTTTTTATAAATGT TTTGACCTTTAATTGGCGGC
Downstream 100 bases:
>100_bases ATAATTATGGTTATTCGTTCAGAGATTGTTTCGATCGGTGACGAACTGCTTAAAGGACAGCGCGTCAATACTAATGCATC TTTTATCGCTTCGGCGCTTT
Product: bifunctional aspartokinase I/homoserine dehydrogenase I
Products: NA
Alternate protein names: Aspartokinase I/homoserine dehydrogenase I; AKI-HDI; Aspartokinase; Homoserine dehydrogenase [H]
Number of amino acids: Translated: 815; Mature: 815
Protein sequence:
>815_residues MKIYKFGGSSLGSAARIRKVAAIIAGARSEGPLVVVVSALFRCTDMLLESANEACLGDENYRKTFEEFDALHRNIAADLF NAEVCSDVVSAMSDELLELSDLLHGVFLLRELSEKSTALILSFGERLSARLISRFLPDGYYVDGRNLVVTDSNPLCARVD RHATEKRIQSALSSCSGVPVVTGYIAAAPDGTVTTLGRGGSDYTASLVGASLSASEIVIWTDVDGFYSADPKRVRDARVL PYISYAEAMELSHAGAKILHPFSIQPAMKASIPVLIRNSFNPDAPGTRIERDVQQEMKDRLPVTGLSSINKVVLLNLAGS GMVGVPGIASRLFSCLALHGINIIFISQASSEQSISLAINPLQAEKAKKILEAEFHSEIESRLIDPLLIRRSLALIAVVG NNMSGHPGVSAQLFETLGKNGINVIAVAQGANEMNISLVIESHDEDKALNCIHESFFLSQRKVHVFLAGTGTIAKSLLQQ ISGHRMNLREEKDLDVVVCGIANTRMIALNNDGIDLERWQEELRPRADDAGIEDYIRLLQERNLHNTIFVDCTASAKVAE RYPELLKANISVVTANKLGMAGPETLYREIVDAERASNARFLYETNVGAGLPIINTLNDLKNSGDKIISIEGVLSGTLSF IFNELRSGGTFSEIVRRAKEAGYTEPDPRDDLSGADFARKFLILGRELGFSLEYADVVCESLVPVDCRGEMSAEEFLVRL RSVDDFYAEEIRRAALEQMTIAYAGEIRNGKASIGVKRVPLESPIAGLSGSENMVVFTTERYRATPLVVRGPGAGAEVTA GGVFADILRIASYLV
Sequences:
>Translated_815_residues MKIYKFGGSSLGSAARIRKVAAIIAGARSEGPLVVVVSALFRCTDMLLESANEACLGDENYRKTFEEFDALHRNIAADLF NAEVCSDVVSAMSDELLELSDLLHGVFLLRELSEKSTALILSFGERLSARLISRFLPDGYYVDGRNLVVTDSNPLCARVD RHATEKRIQSALSSCSGVPVVTGYIAAAPDGTVTTLGRGGSDYTASLVGASLSASEIVIWTDVDGFYSADPKRVRDARVL PYISYAEAMELSHAGAKILHPFSIQPAMKASIPVLIRNSFNPDAPGTRIERDVQQEMKDRLPVTGLSSINKVVLLNLAGS GMVGVPGIASRLFSCLALHGINIIFISQASSEQSISLAINPLQAEKAKKILEAEFHSEIESRLIDPLLIRRSLALIAVVG NNMSGHPGVSAQLFETLGKNGINVIAVAQGANEMNISLVIESHDEDKALNCIHESFFLSQRKVHVFLAGTGTIAKSLLQQ ISGHRMNLREEKDLDVVVCGIANTRMIALNNDGIDLERWQEELRPRADDAGIEDYIRLLQERNLHNTIFVDCTASAKVAE RYPELLKANISVVTANKLGMAGPETLYREIVDAERASNARFLYETNVGAGLPIINTLNDLKNSGDKIISIEGVLSGTLSF IFNELRSGGTFSEIVRRAKEAGYTEPDPRDDLSGADFARKFLILGRELGFSLEYADVVCESLVPVDCRGEMSAEEFLVRL RSVDDFYAEEIRRAALEQMTIAYAGEIRNGKASIGVKRVPLESPIAGLSGSENMVVFTTERYRATPLVVRGPGAGAEVTA GGVFADILRIASYLV >Mature_815_residues MKIYKFGGSSLGSAARIRKVAAIIAGARSEGPLVVVVSALFRCTDMLLESANEACLGDENYRKTFEEFDALHRNIAADLF NAEVCSDVVSAMSDELLELSDLLHGVFLLRELSEKSTALILSFGERLSARLISRFLPDGYYVDGRNLVVTDSNPLCARVD RHATEKRIQSALSSCSGVPVVTGYIAAAPDGTVTTLGRGGSDYTASLVGASLSASEIVIWTDVDGFYSADPKRVRDARVL PYISYAEAMELSHAGAKILHPFSIQPAMKASIPVLIRNSFNPDAPGTRIERDVQQEMKDRLPVTGLSSINKVVLLNLAGS GMVGVPGIASRLFSCLALHGINIIFISQASSEQSISLAINPLQAEKAKKILEAEFHSEIESRLIDPLLIRRSLALIAVVG NNMSGHPGVSAQLFETLGKNGINVIAVAQGANEMNISLVIESHDEDKALNCIHESFFLSQRKVHVFLAGTGTIAKSLLQQ ISGHRMNLREEKDLDVVVCGIANTRMIALNNDGIDLERWQEELRPRADDAGIEDYIRLLQERNLHNTIFVDCTASAKVAE RYPELLKANISVVTANKLGMAGPETLYREIVDAERASNARFLYETNVGAGLPIINTLNDLKNSGDKIISIEGVLSGTLSF IFNELRSGGTFSEIVRRAKEAGYTEPDPRDDLSGADFARKFLILGRELGFSLEYADVVCESLVPVDCRGEMSAEEFLVRL RSVDDFYAEEIRRAALEQMTIAYAGEIRNGKASIGVKRVPLESPIAGLSGSENMVVFTTERYRATPLVVRGPGAGAEVTA GGVFADILRIASYLV
Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]
COG id: COG0527
COG function: function code E; Aspartokinases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ACT domains [H]
Homologues:
Organism=Escherichia coli, GI1786183, Length=836, Percent_Identity=36.6028708133971, Blast_Score=533, Evalue=1e-152, Organism=Escherichia coli, GI1790376, Length=824, Percent_Identity=30.8252427184466, Blast_Score=354, Evalue=2e-98, Organism=Escherichia coli, GI1790455, Length=469, Percent_Identity=28.3582089552239, Blast_Score=137, Evalue=3e-33, Organism=Saccharomyces cerevisiae, GI6320893, Length=506, Percent_Identity=28.0632411067194, Blast_Score=187, Evalue=4e-48, Organism=Saccharomyces cerevisiae, GI6322599, Length=366, Percent_Identity=32.7868852459016, Blast_Score=167, Evalue=6e-42,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR001048 - InterPro: IPR005106 - InterPro: IPR001341 - InterPro: IPR018042 - InterPro: IPR011147 - InterPro: IPR001342 - InterPro: IPR019811 - InterPro: IPR016040 [H]
Pfam domain/function: PF00696 AA_kinase; PF01842 ACT; PF00742 Homoserine_dh; PF03447 NAD_binding_3 [H]
EC number: =2.7.2.4; =1.1.1.3 [H]
Molecular weight: Translated: 88405; Mature: 88405
Theoretical pI: Translated: 5.14; Mature: 5.14
Prosite motif: PS01042 HOMOSER_DHGENASE ; PS00324 ASPARTOKINASE ; PS00178 AA_TRNA_LIGASE_I
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKIYKFGGSSLGSAARIRKVAAIIAGARSEGPLVVVVSALFRCTDMLLESANEACLGDEN CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHH YRKTFEEFDALHRNIAADLFNAEVCSDVVSAMSDELLELSDLLHGVFLLRELSEKSTALI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEE LSFGERLSARLISRFLPDGYYVDGRNLVVTDSNPLCARVDRHATEKRIQSALSSCSGVPV EHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCE VTGYIAAAPDGTVTTLGRGGSDYTASLVGASLSASEIVIWTDVDGFYSADPKRVRDARVL EEEEEEECCCCCEEECCCCCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHCCCCCC PYISYAEAMELSHAGAKILHPFSIQPAMKASIPVLIRNSFNPDAPGTRIERDVQQEMKDR CCHHHHHHHHHHCCCCHHCCCCCCCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC LPVTGLSSINKVVLLNLAGSGMVGVPGIASRLFSCLALHGINIIFISQASSEQSISLAIN CCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEC PLQAEKAKKILEAEFHSEIESRLIDPLLIRRSLALIAVVGNNMSGHPGVSAQLFETLGKN CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCCC GINVIAVAQGANEMNISLVIESHDEDKALNCIHESFFLSQRKVHVFLAGTGTIAKSLLQQ CCEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHH ISGHRMNLREEKDLDVVVCGIANTRMIALNNDGIDLERWQEELRPRADDAGIEDYIRLLQ HCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHH ERNLHNTIFVDCTASAKVAERYPELLKANISVVTANKLGMAGPETLYREIVDAERASNAR HCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCE FLYETNVGAGLPIINTLNDLKNSGDKIISIEGVLSGTLSFIFNELRSGGTFSEIVRRAKE EEEECCCCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH AGYTEPDPRDDLSGADFARKFLILGRELGFSLEYADVVCESLVPVDCRGEMSAEEFLVRL CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHH RSVDDFYAEEIRRAALEQMTIAYAGEIRNGKASIGVKRVPLESPIAGLSGSENMVVFTTE HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEC RYRATPLVVRGPGAGAEVTAGGVFADILRIASYLV CCCCCEEEEECCCCCCCEECCHHHHHHHHHHHHCC >Mature Secondary Structure MKIYKFGGSSLGSAARIRKVAAIIAGARSEGPLVVVVSALFRCTDMLLESANEACLGDEN CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHH YRKTFEEFDALHRNIAADLFNAEVCSDVVSAMSDELLELSDLLHGVFLLRELSEKSTALI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEE LSFGERLSARLISRFLPDGYYVDGRNLVVTDSNPLCARVDRHATEKRIQSALSSCSGVPV EHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCE VTGYIAAAPDGTVTTLGRGGSDYTASLVGASLSASEIVIWTDVDGFYSADPKRVRDARVL EEEEEEECCCCCEEECCCCCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHCCCCCC PYISYAEAMELSHAGAKILHPFSIQPAMKASIPVLIRNSFNPDAPGTRIERDVQQEMKDR CCHHHHHHHHHHCCCCHHCCCCCCCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC LPVTGLSSINKVVLLNLAGSGMVGVPGIASRLFSCLALHGINIIFISQASSEQSISLAIN CCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEC PLQAEKAKKILEAEFHSEIESRLIDPLLIRRSLALIAVVGNNMSGHPGVSAQLFETLGKN CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCCC GINVIAVAQGANEMNISLVIESHDEDKALNCIHESFFLSQRKVHVFLAGTGTIAKSLLQQ CCEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHH ISGHRMNLREEKDLDVVVCGIANTRMIALNNDGIDLERWQEELRPRADDAGIEDYIRLLQ HCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHH ERNLHNTIFVDCTASAKVAERYPELLKANISVVTANKLGMAGPETLYREIVDAERASNAR HCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCE FLYETNVGAGLPIINTLNDLKNSGDKIISIEGVLSGTLSFIFNELRSGGTFSEIVRRAKE EEEECCCCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH AGYTEPDPRDDLSGADFARKFLILGRELGFSLEYADVVCESLVPVDCRGEMSAEEFLVRL CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHH RSVDDFYAEEIRRAALEQMTIAYAGEIRNGKASIGVKRVPLESPIAGLSGSENMVVFTTE HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEC RYRATPLVVRGPGAGAEVTAGGVFADILRIASYLV CCCCCEEEEECCCCCCCEECCHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7003595; 1630901; 7610040; 9278503; 6277952; 2410621; 387092; 6298218; 390305 [H]