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The map label for this gene is pheS

Identifier: 119358273

GI number: 119358273

Start: 2872251

End: 2873276

Strand: Direct

Name: pheS

Synonym: Cpha266_2505

Alternate gene names: 119358273

Gene position: 2872251-2873276 (Clockwise)

Preceding gene: 119358272

Following gene: 119358285

Centisome position: 91.65

GC content: 51.95

Gene sequence:

>1026_bases
ATGGAAAACGCCATTCGCAGTCTGCAGCAGGAAATATCCGAATACGAGCTTGCAAGCATAAAGGACATTGAGGCTTTTCG
TCTCAGGTACACCGTTCGAAAAGGGCTTATCGCTGGCCTTTTCGGACAGCTCAAATCGGTCTTGCCCGCCGATAAACCGC
GAATGGGCCAGTTACTTAACCAACTGCGCCAGACTGCTGATGACAAGCTTGCCGCCGCAACCGCGGAGCTTGCATCAGCA
GAAAGCAAAACAGAACCAAAACTCGATCTGACGCTGCCCGGCAGACGCACGTTCATCGGCAGTGAGCATCCTGTACAAAA
AGTACTCGGTGAGATGAAAGGGATTTTTTCGTCTATGGGGTTCAGCATAGCAACCGGTCCCGAACTCGAGCTCGATCGCT
ATAATTTCGATCTCCTCAACTTTCCCCCGGATCATCCTGCCCGCGATATGCAGGACACCTTTTTCATTACACGGGGAAAC
GCAAACGGCGATGTTCTCCTGAGAACCCATACCTCCCCTGTTCAGATCCGCGTCATGCTTGACCAGAAACCGCCCATACG
GGTTATCTGTCCAGGAAAAGTCTACAGAAACGAAGCAATCAGCTCCCGAAGCTACTGCGTCTTTCATCAGCTTGAAGGAC
TCTATATCGATAAGGGAGTCTCGTTCGCCGACCTGAAAGCAACCATATTCTCATTTGCGCACCAGATGTTCGGCAGTGAC
GTAAAGCTGCGCTTCCGCCCGAGCTTTTTCCCCTTTACAGAACCATCGGCAGAAGTAGACGTTTCCTGTTACCTCTGCGG
AGGCAAAGGGTGCCGCGTCTGTAAAAAATCAGGATGGCTTGAAATCATGGGCTGCGGCATGGTTCACCCCAACGTCATGC
GCAACAGCGGCATTGATCCCGAAAAATGGTCAGGCTATGCTTTCGGCATGGGTGTCGACCGCACCGTGCTCCTGCGCTAC
AAAATCGACGACATCAGGCTGCTTTTTGAAAACGATGTTCGCATGCTCCGACAATTTCCGGCTTGA

Upstream 100 bases:

>100_bases
GAAATCGACCGTAAAACTCTTGCTGAGATTGCCGTAAAAGATCCGGCAGCATTTTCACAGATCGTCAAAGCTGTTATCGA
ATAAGTATACCCCTGTTTTT

Downstream 100 bases:

>100_bases
AAAGCCGCATTAAGCCAAAAGGCCAATACCCTTTGTCAGCAAGCCAATTATTTTCATACACCCATCCATAGCCTTGACAA
TGGAGTCGAGCTCCTTTTTC

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MENAIRSLQQEISEYELASIKDIEAFRLRYTVRKGLIAGLFGQLKSVLPADKPRMGQLLNQLRQTADDKLAAATAELASA
ESKTEPKLDLTLPGRRTFIGSEHPVQKVLGEMKGIFSSMGFSIATGPELELDRYNFDLLNFPPDHPARDMQDTFFITRGN
ANGDVLLRTHTSPVQIRVMLDQKPPIRVICPGKVYRNEAISSRSYCVFHQLEGLYIDKGVSFADLKATIFSFAHQMFGSD
VKLRFRPSFFPFTEPSAEVDVSCYLCGGKGCRVCKKSGWLEIMGCGMVHPNVMRNSGIDPEKWSGYAFGMGVDRTVLLRY
KIDDIRLLFENDVRMLRQFPA

Sequences:

>Translated_341_residues
MENAIRSLQQEISEYELASIKDIEAFRLRYTVRKGLIAGLFGQLKSVLPADKPRMGQLLNQLRQTADDKLAAATAELASA
ESKTEPKLDLTLPGRRTFIGSEHPVQKVLGEMKGIFSSMGFSIATGPELELDRYNFDLLNFPPDHPARDMQDTFFITRGN
ANGDVLLRTHTSPVQIRVMLDQKPPIRVICPGKVYRNEAISSRSYCVFHQLEGLYIDKGVSFADLKATIFSFAHQMFGSD
VKLRFRPSFFPFTEPSAEVDVSCYLCGGKGCRVCKKSGWLEIMGCGMVHPNVMRNSGIDPEKWSGYAFGMGVDRTVLLRY
KIDDIRLLFENDVRMLRQFPA
>Mature_341_residues
MENAIRSLQQEISEYELASIKDIEAFRLRYTVRKGLIAGLFGQLKSVLPADKPRMGQLLNQLRQTADDKLAAATAELASA
ESKTEPKLDLTLPGRRTFIGSEHPVQKVLGEMKGIFSSMGFSIATGPELELDRYNFDLLNFPPDHPARDMQDTFFITRGN
ANGDVLLRTHTSPVQIRVMLDQKPPIRVICPGKVYRNEAISSRSYCVFHQLEGLYIDKGVSFADLKATIFSFAHQMFGSD
VKLRFRPSFFPFTEPSAEVDVSCYLCGGKGCRVCKKSGWLEIMGCGMVHPNVMRNSGIDPEKWSGYAFGMGVDRTVLLRY
KIDDIRLLFENDVRMLRQFPA

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily

Homologues:

Organism=Homo sapiens, GI4758340, Length=276, Percent_Identity=29.7101449275362, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI5729820, Length=294, Percent_Identity=27.891156462585, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1788007, Length=327, Percent_Identity=44.3425076452599, Blast_Score=296, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI32563657, Length=275, Percent_Identity=30.5454545454545, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17508957, Length=275, Percent_Identity=30.1818181818182, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32566635, Length=246, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321087, Length=275, Percent_Identity=29.4545454545455, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6325304, Length=100, Percent_Identity=37, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18858079, Length=284, Percent_Identity=29.2253521126761, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17137424, Length=316, Percent_Identity=25.9493670886076, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFA_CHLPD (A1BJB6)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912917.1
- ProteinModelPortal:   A1BJB6
- SMR:   A1BJB6
- STRING:   A1BJB6
- GeneID:   4569592
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2505
- NMPDR:   fig|290317.7.peg.2621
- eggNOG:   COG0016
- HOGENOM:   HBG284353
- OMA:   FRASYFP
- ProtClustDB:   PRK00488
- GO:   GO:0005737
- HAMAP:   MF_00281
- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978
- PANTHER:   PTHR11538
- TIGRFAMs:   TIGR00468

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d; SSF46589 tRNA_binding_arm

EC number: =6.1.1.20

Molecular weight: Translated: 38377; Mature: 38377

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENAIRSLQQEISEYELASIKDIEAFRLRYTVRKGLIAGLFGQLKSVLPADKPRMGQLLN
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
QLRQTADDKLAAATAELASAESKTEPKLDLTLPGRRTFIGSEHPVQKVLGEMKGIFSSMG
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEECCCCCCHHHHHHHHHHHHHHCC
FSIATGPELELDRYNFDLLNFPPDHPARDMQDTFFITRGNANGDVLLRTHTSPVQIRVML
CEEECCCCCEEECCCCEEECCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCEEEEEEE
DQKPPIRVICPGKVYRNEAISSRSYCVFHQLEGLYIDKGVSFADLKATIFSFAHQMFGSD
CCCCCEEEECCCHHHHHHHCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHCCCC
VKLRFRPSFFPFTEPSAEVDVSCYLCGGKGCRVCKKSGWLEIMGCGMVHPNVMRNSGIDP
EEEEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHCCCCEEEEECCCCCCHHHHCCCCCC
EKWSGYAFGMGVDRTVLLRYKIDDIRLLFENDVRMLRQFPA
CCCCCEEEECCCCEEEEEEEEECCEEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MENAIRSLQQEISEYELASIKDIEAFRLRYTVRKGLIAGLFGQLKSVLPADKPRMGQLLN
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
QLRQTADDKLAAATAELASAESKTEPKLDLTLPGRRTFIGSEHPVQKVLGEMKGIFSSMG
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEECCCCCCHHHHHHHHHHHHHHCC
FSIATGPELELDRYNFDLLNFPPDHPARDMQDTFFITRGNANGDVLLRTHTSPVQIRVML
CEEECCCCCEEECCCCEEECCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCEEEEEEE
DQKPPIRVICPGKVYRNEAISSRSYCVFHQLEGLYIDKGVSFADLKATIFSFAHQMFGSD
CCCCCEEEECCCHHHHHHHCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHCCCC
VKLRFRPSFFPFTEPSAEVDVSCYLCGGKGCRVCKKSGWLEIMGCGMVHPNVMRNSGIDP
EEEEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHCCCCEEEEECCCCCCHHHHCCCCCC
EKWSGYAFGMGVDRTVLLRYKIDDIRLLFENDVRMLRQFPA
CCCCCEEEECCCCEEEEEEEEECCEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA