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The map label for this gene is obgE

Identifier: 119358213

GI number: 119358213

Start: 2819306

End: 2820319

Strand: Reverse

Name: obgE

Synonym: Cpha266_2445

Alternate gene names: 119358213

Gene position: 2820319-2819306 (Counterclockwise)

Preceding gene: 119358215

Following gene: 119358212

Centisome position: 89.99

GC content: 51.87

Gene sequence:

>1014_bases
GTGAAGTTTGTCGATAGTGCGACCATTTCTATTCAGGCAGGTGATGGCGGAAGAGGGTGTGTGAGTTTTCGCCGGGAAAA
ATTTGTGCCCAAGGGCGGTCCCGACGGCGGCGACGGCGGAAGGGGCGGTCATATTTATTTGCGGGCTAACAAGCAGCTTG
CAACGCTTCTGGATTTCAGATATAGAAAGCAGTATCTTGCCACAAGGGGTGCGCATGGGCAGGGTTCGCGTAAAACAGGT
AAAGATGGCTCCGATATTGTCATCGAGATTCCGTGCGGCACGCTTGTGAAAAATGCGCAGACCCACGAGCTTATAGCTGA
TCTTACCGAGGATGGCCAGGAGATGCTTGTTGCGCGCGGAGGAAAGGGCGGCAGAGGAAACCAGCATTTTGCGACCCCTA
CCCGGCAAGCGCCAAGATATGCCGAGCCCGGTCTGAAAGGCGAGGCTTTCGAGCTTGAGATGGAGCTGAAACTGATGGCC
GATGTCGGGCTTGTCGGGTTTCCAAATGCCGGGAAATCAACGCTGATTTCAGTGCTGAGCGCCGCAAAACCCAAAATTGC
CGACTATCCGTTTACAACCCTTGTGCCGAATCTTGGTATCGTGCGTTATGAGGAGTACAAGTCTTTTGTGATGGCCGATA
TTCCCGGAATTATTGAGGGCGCGGCTGAAGGAAAAGGACTTGGTCTGCAGTTCCTTCGCCATATTGAGAGAACAAAAATT
CTTGTGGTGCTTGTTGCTGCCGATGCTGCCGATATTGCGCTGGAGTATCAGACGCTTGTACAGGAATTGGAGAAATTTGA
CAGCGGACTGCTTTTGAAGCCGAGAATTGCCGTGATTACAAAAATGGATATTGCTTCGGAGGATATGGTTGTGCCTGAGC
TTGAAGGGGTTAAGCTGCTCATGATTTCAAGCGTTACAGGCAAGGGACTTAAGGAGCTCAAAGATGAGCTCTGGAGGCAG
GTCTCCACCTGCTCTCGCAGCGAGGATCAACCGCTGGATGAACATTTGGGGTAA

Upstream 100 bases:

>100_bases
ATTTTTTTTAGCAGAGGTTACAGCCATGTGTCGATAAGTATTTGATGAATGGTGTTAACTTACGCAAACAGAGAGAGTAT
TCAAAAAGGCAGGTGAGCGA

Downstream 100 bases:

>100_bases
CGATGCCGAAGCATGAAACAACGGTAAGGCCGGCTTGTCTTGCGGATGCCGACGCAATTGCGGCACTGACGTCGGTCTAT
GCGCGAAATGGAGTTATGCT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKFVDSATISIQAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHIYLRANKQLATLLDFRYRKQYLATRGAHGQGSRKTG
KDGSDIVIEIPCGTLVKNAQTHELIADLTEDGQEMLVARGGKGGRGNQHFATPTRQAPRYAEPGLKGEAFELEMELKLMA
DVGLVGFPNAGKSTLISVLSAAKPKIADYPFTTLVPNLGIVRYEEYKSFVMADIPGIIEGAAEGKGLGLQFLRHIERTKI
LVVLVAADAADIALEYQTLVQELEKFDSGLLLKPRIAVITKMDIASEDMVVPELEGVKLLMISSVTGKGLKELKDELWRQ
VSTCSRSEDQPLDEHLG

Sequences:

>Translated_337_residues
MKFVDSATISIQAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHIYLRANKQLATLLDFRYRKQYLATRGAHGQGSRKTG
KDGSDIVIEIPCGTLVKNAQTHELIADLTEDGQEMLVARGGKGGRGNQHFATPTRQAPRYAEPGLKGEAFELEMELKLMA
DVGLVGFPNAGKSTLISVLSAAKPKIADYPFTTLVPNLGIVRYEEYKSFVMADIPGIIEGAAEGKGLGLQFLRHIERTKI
LVVLVAADAADIALEYQTLVQELEKFDSGLLLKPRIAVITKMDIASEDMVVPELEGVKLLMISSVTGKGLKELKDELWRQ
VSTCSRSEDQPLDEHLG
>Mature_337_residues
MKFVDSATISIQAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHIYLRANKQLATLLDFRYRKQYLATRGAHGQGSRKTG
KDGSDIVIEIPCGTLVKNAQTHELIADLTEDGQEMLVARGGKGGRGNQHFATPTRQAPRYAEPGLKGEAFELEMELKLMA
DVGLVGFPNAGKSTLISVLSAAKPKIADYPFTTLVPNLGIVRYEEYKSFVMADIPGIIEGAAEGKGLGLQFLRHIERTKI
LVVLVAADAADIALEYQTLVQELEKFDSGLLLKPRIAVITKMDIASEDMVVPELEGVKLLMISSVTGKGLKELKDELWRQ
VSTCSRSEDQPLDEHLG

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=314, Percent_Identity=40.1273885350318, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI111955139, Length=363, Percent_Identity=34.7107438016529, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI111955063, Length=199, Percent_Identity=36.6834170854271, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI4758796, Length=115, Percent_Identity=41.7391304347826, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4557537, Length=123, Percent_Identity=35.7723577235772, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789574, Length=324, Percent_Identity=49.3827160493827, Blast_Score=274, Evalue=6e-75,
Organism=Escherichia coli, GI1787454, Length=96, Percent_Identity=37.5, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=300, Percent_Identity=41, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17552324, Length=308, Percent_Identity=33.1168831168831, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71981008, Length=131, Percent_Identity=35.8778625954198, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=86, Percent_Identity=45.3488372093023, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=165, Percent_Identity=43.030303030303, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=106, Percent_Identity=40.5660377358491, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321612, Length=155, Percent_Identity=33.5483870967742, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20129375, Length=333, Percent_Identity=38.7387387387387, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI24585318, Length=230, Percent_Identity=41.7391304347826, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI21356473, Length=156, Percent_Identity=35.8974358974359, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17981711, Length=115, Percent_Identity=42.6086956521739, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640873, Length=142, Percent_Identity=33.0985915492958, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24640877, Length=142, Percent_Identity=33.0985915492958, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24640875, Length=142, Percent_Identity=33.0985915492958, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_CHLPD (A1BJ56)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912857.1
- ProteinModelPortal:   A1BJ56
- SMR:   A1BJ56
- STRING:   A1BJ56
- GeneID:   4568873
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2445
- NMPDR:   fig|290317.7.peg.2559
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36495; Mature: 36495

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDSATISIQAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHIYLRANKQLATLLDFR
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHH
YRKQYLATRGAHGQGSRKTGKDGSDIVIEIPCGTLVKNAQTHELIADLTEDGQEMLVARG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHCCCEEEEECC
GKGGRGNQHFATPTRQAPRYAEPGLKGEAFELEMELKLMADVGLVGFPNAGKSTLISVLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHH
AAKPKIADYPFTTLVPNLGIVRYEEYKSFVMADIPGIIEGAAEGKGLGLQFLRHIERTKI
HCCCCCCCCCHHHHCCCCCEEEEHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHCEE
LVVLVAADAADIALEYQTLVQELEKFDSGLLLKPRIAVITKMDIASEDMVVPELEGVKLL
EEEEEECCCHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCCCCCCCCCCCCCEEEE
MISSVTGKGLKELKDELWRQVSTCSRSEDQPLDEHLG
EEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure
MKFVDSATISIQAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHIYLRANKQLATLLDFR
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHH
YRKQYLATRGAHGQGSRKTGKDGSDIVIEIPCGTLVKNAQTHELIADLTEDGQEMLVARG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHCCCEEEEECC
GKGGRGNQHFATPTRQAPRYAEPGLKGEAFELEMELKLMADVGLVGFPNAGKSTLISVLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHH
AAKPKIADYPFTTLVPNLGIVRYEEYKSFVMADIPGIIEGAAEGKGLGLQFLRHIERTKI
HCCCCCCCCCHHHHCCCCCEEEEHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHCEE
LVVLVAADAADIALEYQTLVQELEKFDSGLLLKPRIAVITKMDIASEDMVVPELEGVKLL
EEEEEECCCHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCCCCCCCCCCCCCEEEE
MISSVTGKGLKELKDELWRQVSTCSRSEDQPLDEHLG
EEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA