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The map label for this gene is arsA1 [H]

Identifier: 119358069

GI number: 119358069

Start: 2629745

End: 2630899

Strand: Reverse

Name: arsA1 [H]

Synonym: Cpha266_2297

Alternate gene names: 119358069

Gene position: 2630899-2629745 (Counterclockwise)

Preceding gene: 119358070

Following gene: 119358065

Centisome position: 83.95

GC content: 45.89

Gene sequence:

>1155_bases
ATGAGAATTATTCTTTACCTGGGTAAGGGCGGAGTTGGAAAAACTACCGTCTCGGCTTCAACAGCAACTGCAATTGCCCG
CCGCGGAGAACGGGTGCTTATTATGAGTACGGATGTAGCCCACAGTCTTGCTGACGCTTTGGGTGTGGAATTAAGCCCGA
CTCCTCTTGAAGTAGAACAAAATCTGTTTGCGATGGAGGTCAATGTTCTGACAGAAATCAGGGAGAACTGGTCTGAGCTT
TATTCCTATTTTTCCTCCATTCTCATGCATGACGGCGCAAATGAGGTCGTTGCTGAAGAACTTGCCATTATGCCGGGCAT
GGAAGAGATGATCAGTCTCCGATATATATGGAAAGCTGCCAAGTCCGGAAATTATGATGTTGTGGTTGTTGACGCAGCTC
CGACAGGTGAAACCATGCGCCTGCTTGGCATGCCGGAATCCTATGGATGGTATTCCGAGAAAATCGGTGGATGGCACTCT
AAAGCCATTGGCTTTGCTGCGCCGCTGCTGTCGAAATTCATGCCTAAAAAGAATATTTTCAAGTTGATGCCTGAGGTGAA
CGAGCATATGAAAGAGCTGCACACCATGCTGCAGGACAAAAACATCACCACGTTCAGAGTTGTCCTCAACCCTGAGAACA
TGGTGATCAAGGAAGCTCTTCGAGTTCAGACCTATCTGAATCTTTTCGGTTACAAGCTCGATGCCGCCATAGTCAACAAG
GTTCTTCCTGAAAGCTCATCAGACCAGTATCTGCAATGCCTTATTGACCTGCAGGCCAAGTATCTGAAGGTTATTGAAAA
CTGTTTTTTCCCTGTTCCGATTTTCAGGGCAAAACAGTCCACGGCTGAGGTTATCACCCCGGACAGGCTTTATGAACTGA
GTCAGGAGATTTTTGCTGATCAGAATCCTTCAGCGGTGCTTTACAGCAATGAAAAGACCCAGACGCTTGAGAAAATAAAC
GGCAAATACGTTCTGAGCCTCTATCTGCCTAATGTAGAGGTGACAAAGCTGAATGTCAATATCAAGGGAGATGAATTACT
GATTGACATCAACAATTTCCGTAAAAGCATTATTTTGCCCAATGTTCTCGTTGGAAGAAAAACGGAGGGGGCCGACTTTG
TTTCCGGAAACCTCAATATAACCTTTGCAAACTGA

Upstream 100 bases:

>100_bases
GTTCTTCAGAATCAATCCAGTCCGGTGAATCCAATCCGGATGATCAATCTCATAAACGCACAATAAAGATCAAGTCCACA
CAATAGTTTTTTTAAACAAC

Downstream 100 bases:

>100_bases
GCTTGCCTTGAGTTTTTGAGGTTGGATGTCACATCTTTTTCGAAAGGCCCGCTGCATGAATACCGGATGCAGCGGGCCTT
TTTTATTTACCTTCTGAACT

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase 1; Arsenite-translocating ATPase 1; Arsenite-transporting ATPase 1 [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MRIILYLGKGGVGKTTVSASTATAIARRGERVLIMSTDVAHSLADALGVELSPTPLEVEQNLFAMEVNVLTEIRENWSEL
YSYFSSILMHDGANEVVAEELAIMPGMEEMISLRYIWKAAKSGNYDVVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHS
KAIGFAAPLLSKFMPKKNIFKLMPEVNEHMKELHTMLQDKNITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAIVNK
VLPESSSDQYLQCLIDLQAKYLKVIENCFFPVPIFRAKQSTAEVITPDRLYELSQEIFADQNPSAVLYSNEKTQTLEKIN
GKYVLSLYLPNVEVTKLNVNIKGDELLIDINNFRKSIILPNVLVGRKTEGADFVSGNLNITFAN

Sequences:

>Translated_384_residues
MRIILYLGKGGVGKTTVSASTATAIARRGERVLIMSTDVAHSLADALGVELSPTPLEVEQNLFAMEVNVLTEIRENWSEL
YSYFSSILMHDGANEVVAEELAIMPGMEEMISLRYIWKAAKSGNYDVVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHS
KAIGFAAPLLSKFMPKKNIFKLMPEVNEHMKELHTMLQDKNITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAIVNK
VLPESSSDQYLQCLIDLQAKYLKVIENCFFPVPIFRAKQSTAEVITPDRLYELSQEIFADQNPSAVLYSNEKTQTLEKIN
GKYVLSLYLPNVEVTKLNVNIKGDELLIDINNFRKSIILPNVLVGRKTEGADFVSGNLNITFAN
>Mature_384_residues
MRIILYLGKGGVGKTTVSASTATAIARRGERVLIMSTDVAHSLADALGVELSPTPLEVEQNLFAMEVNVLTEIRENWSEL
YSYFSSILMHDGANEVVAEELAIMPGMEEMISLRYIWKAAKSGNYDVVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHS
KAIGFAAPLLSKFMPKKNIFKLMPEVNEHMKELHTMLQDKNITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAIVNK
VLPESSSDQYLQCLIDLQAKYLKVIENCFFPVPIFRAKQSTAEVITPDRLYELSQEIFADQNPSAVLYSNEKTQTLEKIN
GKYVLSLYLPNVEVTKLNVNIKGDELLIDINNFRKSIILPNVLVGRKTEGADFVSGNLNITFAN

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=266, Percent_Identity=27.8195488721804, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17557003, Length=277, Percent_Identity=27.7978339350181, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6320103, Length=315, Percent_Identity=24.7619047619048, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24586297, Length=309, Percent_Identity=29.126213592233, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 43017; Mature: 43017

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIILYLGKGGVGKTTVSASTATAIARRGERVLIMSTDVAHSLADALGVELSPTPLEVEQ
CEEEEEECCCCCCCEEECHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCCCCCCHHCC
NLFAMEVNVLTEIRENWSELYSYFSSILMHDGANEVVAEELAIMPGMEEMISLRYIWKAA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
KSGNYDVVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHSKAIGFAAPLLSKFMPKKNIF
CCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCHHHHH
KLMPEVNEHMKELHTMLQDKNITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAIVNK
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VLPESSSDQYLQCLIDLQAKYLKVIENCFFPVPIFRAKQSTAEVITPDRLYELSQEIFAD
HCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCC
QNPSAVLYSNEKTQTLEKINGKYVLSLYLPNVEVTKLNVNIKGDELLIDINNFRKSIILP
CCCCEEEECCCHHHHHHHCCCEEEEEEEECCEEEEEEEEEECCCEEEEEHHHHHHHHCCC
NVLVGRKTEGADFVSGNLNITFAN
CCEECCCCCCCCEEECCEEEEEEC
>Mature Secondary Structure
MRIILYLGKGGVGKTTVSASTATAIARRGERVLIMSTDVAHSLADALGVELSPTPLEVEQ
CEEEEEECCCCCCCEEECHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCCCCCCHHCC
NLFAMEVNVLTEIRENWSELYSYFSSILMHDGANEVVAEELAIMPGMEEMISLRYIWKAA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
KSGNYDVVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHSKAIGFAAPLLSKFMPKKNIF
CCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCHHHHH
KLMPEVNEHMKELHTMLQDKNITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAIVNK
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VLPESSSDQYLQCLIDLQAKYLKVIENCFFPVPIFRAKQSTAEVITPDRLYELSQEIFAD
HCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCC
QNPSAVLYSNEKTQTLEKINGKYVLSLYLPNVEVTKLNVNIKGDELLIDINNFRKSIILP
CCCCEEEECCCHHHHHHHCCCEEEEEEEECCEEEEEEEEEECCCEEEEEHHHHHHHHCCC
NVLVGRKTEGADFVSGNLNITFAN
CCEECCCCCCCCEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]