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The map label for this gene is alr [H]

Identifier: 119358056

GI number: 119358056

Start: 2615598

End: 2616728

Strand: Direct

Name: alr [H]

Synonym: Cpha266_2284

Alternate gene names: 119358056

Gene position: 2615598-2616728 (Clockwise)

Preceding gene: 119358055

Following gene: 119358057

Centisome position: 83.46

GC content: 49.07

Gene sequence:

>1131_bases
ATGACGATCGAAACGCCCTCCCTGAACATGGCAGAAGCCTCTATCTCGTTAGGTCATCTGAAACATAACATCCGGGAGAT
AAAGCAATGCGTGGGAACCGGTGTTCGCATCATGGGCATTGTAAAGGCAAATGCTTATGGTCATAACATGCAAAAAGTCG
CCGAAACACTTGAAGCGGAGGGTATCAGCGATTTCGGGGTTGCCAACATCCATGAGGCTATTGAACTGAAAACTGGAGGT
GCGCTTAAAAAGCCGGCAAACATACTCTCTTTTTCCTCTCCGATCATTCAGCAAATAGAGTACTACCTGCACCACCAGAT
CGACATGACTCTCTGCGATGCCAACATTATGAAAGCAGCATCGGCAATCGCTGAAAAACACAACAAAAAAATCGGCGTGC
ACCTCAAGGTGGATACCGGAATGGGGCGGCTTGGGCTCCCGCCTCTTCAGGCGCTTGAGCTCCTCAGAGAAACAGAGCGA
CAGCCGGGTCTTGAACTTAAAGGGGTCTACACTCATTTTGCCGAGAGTGCCAACGATGACTTTACCCGGCGCCAGTTCAA
AGAGTTCAAAACCATGACGGACGCATATGAGACTGCAAGCGGCAAAACTCTCTGTAAACACGCCGCCAGCAGCGGAACGT
TGCTGAACAATCCTGAAATGCGGCTCGACATGGTTCGCCCGGGCATTCTGCTCTATGGTTATAAACCCTATCCGGCGCTC
CCCTCTTCGATAACAGTACGTCCTGTCATGCAGTTCGAGGCAAAGGTTATTTTCATTAAAACCGTCGCTAAAGACGCAAC
CATCAGTTATAACCGCACATGGAAAGCTGCGCGTCCGGTAAAAATCGCAACCATATCAGCAGGATATGCGGATGGGTACC
ACAGAGCGCTCTCGAATCATGCTACCGTTTTTATCAACGGAAAATCTTTTCAGCAGGTCGGTACCGTAACCATGGATCAG
TTTATGGTTGATCTCGGCACAGAAAGTGATGTAAAAATTGGTGATCGTGCTATATTATTCGGTTGGGAGGGCCCTTGCCT
CGAAGAGCTTGCCGGGAGTATCGGCAGTATAAGCTATGAGCTCCTCTGTTCCGTATCCAGCAGAGTAAAACGGGTGTTTA
CTGATGATTAA

Upstream 100 bases:

>100_bases
TTTTCCCTTTTTATCTTCCCCTTTCTCTTTTCTTTCTTAAACTTCTTGCTGAAAGCGAGCAATCAGCCGCCCTGTTTTCT
TGCAAAACCATAACACTGCG

Downstream 100 bases:

>100_bases
CCACAGAGGGAACCATGAACCCCTTTGATCAGCTTTCAAGAAAACTCAGTCTGACAAGAACGGAAGTGTCAGTAATTTCA
CTTCTGCTGCTCTTCCTTTT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MTIETPSLNMAEASISLGHLKHNIREIKQCVGTGVRIMGIVKANAYGHNMQKVAETLEAEGISDFGVANIHEAIELKTGG
ALKKPANILSFSSPIIQQIEYYLHHQIDMTLCDANIMKAASAIAEKHNKKIGVHLKVDTGMGRLGLPPLQALELLRETER
QPGLELKGVYTHFAESANDDFTRRQFKEFKTMTDAYETASGKTLCKHAASSGTLLNNPEMRLDMVRPGILLYGYKPYPAL
PSSITVRPVMQFEAKVIFIKTVAKDATISYNRTWKAARPVKIATISAGYADGYHRALSNHATVFINGKSFQQVGTVTMDQ
FMVDLGTESDVKIGDRAILFGWEGPCLEELAGSIGSISYELLCSVSSRVKRVFTDD

Sequences:

>Translated_376_residues
MTIETPSLNMAEASISLGHLKHNIREIKQCVGTGVRIMGIVKANAYGHNMQKVAETLEAEGISDFGVANIHEAIELKTGG
ALKKPANILSFSSPIIQQIEYYLHHQIDMTLCDANIMKAASAIAEKHNKKIGVHLKVDTGMGRLGLPPLQALELLRETER
QPGLELKGVYTHFAESANDDFTRRQFKEFKTMTDAYETASGKTLCKHAASSGTLLNNPEMRLDMVRPGILLYGYKPYPAL
PSSITVRPVMQFEAKVIFIKTVAKDATISYNRTWKAARPVKIATISAGYADGYHRALSNHATVFINGKSFQQVGTVTMDQ
FMVDLGTESDVKIGDRAILFGWEGPCLEELAGSIGSISYELLCSVSSRVKRVFTDD
>Mature_375_residues
TIETPSLNMAEASISLGHLKHNIREIKQCVGTGVRIMGIVKANAYGHNMQKVAETLEAEGISDFGVANIHEAIELKTGGA
LKKPANILSFSSPIIQQIEYYLHHQIDMTLCDANIMKAASAIAEKHNKKIGVHLKVDTGMGRLGLPPLQALELLRETERQ
PGLELKGVYTHFAESANDDFTRRQFKEFKTMTDAYETASGKTLCKHAASSGTLLNNPEMRLDMVRPGILLYGYKPYPALP
SSITVRPVMQFEAKVIFIKTVAKDATISYNRTWKAARPVKIATISAGYADGYHRALSNHATVFINGKSFQQVGTVTMDQF
MVDLGTESDVKIGDRAILFGWEGPCLEELAGSIGSISYELLCSVSSRVKRVFTDD

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=380, Percent_Identity=31.0526315789474, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787439, Length=367, Percent_Identity=30.2452316076294, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41326; Mature: 41195

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIETPSLNMAEASISLGHLKHNIREIKQCVGTGVRIMGIVKANAYGHNMQKVAETLEAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHC
GISDFGVANIHEAIELKTGGALKKPANILSFSSPIIQQIEYYLHHQIDMTLCDANIMKAA
CCCCCCHHHHHHHHEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCEEEEECHHHHHHH
SAIAEKHNKKIGVHLKVDTGMGRLGLPPLQALELLRETERQPGLELKGVYTHFAESANDD
HHHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCH
FTRRQFKEFKTMTDAYETASGKTLCKHAASSGTLLNNPEMRLDMVRPGILLYGYKPYPAL
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEECCCCCEEEEECCCEEEEECCCCCCC
PSSITVRPVMQFEAKVIFIKTVAKDATISYNRTWKAARPVKIATISAGYADGYHRALSNH
CCCEEEEEEEECCEEEEEEEEECCCCEEEECCCCCCCCCEEEEEEECCCCHHHHHHHCCC
ATVFINGKSFQQVGTVTMDQFMVDLGTESDVKIGDRAILFGWEGPCLEELAGSIGSISYE
CEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEECCEEEEEECCCCHHHHHCCHHCCHHHH
LLCSVSSRVKRVFTDD
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIETPSLNMAEASISLGHLKHNIREIKQCVGTGVRIMGIVKANAYGHNMQKVAETLEAE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHC
GISDFGVANIHEAIELKTGGALKKPANILSFSSPIIQQIEYYLHHQIDMTLCDANIMKAA
CCCCCCHHHHHHHHEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCEEEEECHHHHHHH
SAIAEKHNKKIGVHLKVDTGMGRLGLPPLQALELLRETERQPGLELKGVYTHFAESANDD
HHHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCH
FTRRQFKEFKTMTDAYETASGKTLCKHAASSGTLLNNPEMRLDMVRPGILLYGYKPYPAL
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEECCCCCEEEEECCCEEEEECCCCCCC
PSSITVRPVMQFEAKVIFIKTVAKDATISYNRTWKAARPVKIATISAGYADGYHRALSNH
CCCEEEEEEEECCEEEEEEEEECCCCEEEECCCCCCCCCEEEEEEECCCCHHHHHHHCCC
ATVFINGKSFQQVGTVTMDQFMVDLGTESDVKIGDRAILFGWEGPCLEELAGSIGSISYE
CEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEECCEEEEEECCCCHHHHHCCHHCCHHHH
LLCSVSSRVKRVFTDD
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]