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The map label for this gene is fkpB [C]

Identifier: 119358039

GI number: 119358039

Start: 2597917

End: 2598345

Strand: Reverse

Name: fkpB [C]

Synonym: Cpha266_2267

Alternate gene names: 119358039

Gene position: 2598345-2597917 (Counterclockwise)

Preceding gene: 119358040

Following gene: 119358038

Centisome position: 82.91

GC content: 49.65

Gene sequence:

>429_bases
ATGGCGCAAGCAAAAGAGGGAGATATTGTAAAAGTACACTATACTGGAAAGTTGGATGACGGCACCATGTTTGACACATC
GGCAAACCGCGATCCTCTTGAGTTTACCGTTGGTGCCGGACATGTTATTCCAGGGTTTGACATAGCCGTGATCGATATGG
CTCCGGGGGAGATTAAAGTAACGGTTATTCCGGTAGACGAGGCTTATGGCCCTCACAGTACTGATCTTGTCACACCGGTG
AGTCGTGAACGTTTTCCTGCCGATATGGAACTTGAAATCGGACAGCAGCTTCAGGTTGGTCTTGCCGACGGACAGGAGGC
TATTGTGATGATTGTCGATCTTGACGAAACATCGGTTACGCTTGATGCCAATCACCCGCTTGCCGGTCAGAACCTGACCT
TCGAGATTGAGCTGGTGGAGATCGTATAG

Upstream 100 bases:

>100_bases
TTCCGAATGCCCCAGGGGGAGGAAAAGGGATTGAAATGGCAGGCAACTTATTTAATTTATAATAGTTAAAGTATTTTTTA
TCATAAACAGGGAGGAGATT

Downstream 100 bases:

>100_bases
GAAATATAAAAACCTGTTGAGCGTTTCGATGGCTTTGTCGCGACTCCGTCCGCCCGGCCTTCGAACCGCTCACGGCGGTT
TTCGAAACACCCGCAAAAAC

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MAQAKEGDIVKVHYTGKLDDGTMFDTSANRDPLEFTVGAGHVIPGFDIAVIDMAPGEIKVTVIPVDEAYGPHSTDLVTPV
SRERFPADMELEIGQQLQVGLADGQEAIVMIVDLDETSVTLDANHPLAGQNLTFEIELVEIV

Sequences:

>Translated_142_residues
MAQAKEGDIVKVHYTGKLDDGTMFDTSANRDPLEFTVGAGHVIPGFDIAVIDMAPGEIKVTVIPVDEAYGPHSTDLVTPV
SRERFPADMELEIGQQLQVGLADGQEAIVMIVDLDETSVTLDANHPLAGQNLTFEIELVEIV
>Mature_141_residues
AQAKEGDIVKVHYTGKLDDGTMFDTSANRDPLEFTVGAGHVIPGFDIAVIDMAPGEIKVTVIPVDEAYGPHSTDLVTPVS
RERFPADMELEIGQQLQVGLADGQEAIVMIVDLDETSVTLDANHPLAGQNLTFEIELVEIV

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=69, Percent_Identity=43.4782608695652, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI17149844, Length=69, Percent_Identity=43.4782608695652, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI17149842, Length=69, Percent_Identity=43.4782608695652, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI7706131, Length=64, Percent_Identity=46.875, Blast_Score=66, Evalue=8e-12,
Organism=Homo sapiens, GI219842220, Length=64, Percent_Identity=46.875, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1786211, Length=133, Percent_Identity=36.0902255639098, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1789748, Length=133, Percent_Identity=30.8270676691729, Blast_Score=63, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324194, Length=89, Percent_Identity=40.4494382022472, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320727, Length=87, Percent_Identity=44.8275862068966, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24655568, Length=76, Percent_Identity=44.7368421052632, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356629, Length=63, Percent_Identity=49.2063492063492, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15287; Mature: 15156

Theoretical pI: Translated: 3.88; Mature: 3.88

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAKEGDIVKVHYTGKLDDGTMFDTSANRDPLEFTVGAGHVIPGFDIAVIDMAPGEIKV
CCCCCCCCEEEEEEECCCCCCEEEECCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEE
TVIPVDEAYGPHSTDLVTPVSRERFPADMELEIGQQLQVGLADGQEAIVMIVDLDETSVT
EEEECCCCCCCCCCCEECCCCHHCCCCCEEEECCCEEEEEECCCCEEEEEEEECCCCEEE
LDANHPLAGQNLTFEIELVEIV
EECCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
AQAKEGDIVKVHYTGKLDDGTMFDTSANRDPLEFTVGAGHVIPGFDIAVIDMAPGEIKV
CCCCCCCEEEEEEECCCCCCEEEECCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEE
TVIPVDEAYGPHSTDLVTPVSRERFPADMELEIGQQLQVGLADGQEAIVMIVDLDETSVT
EEEECCCCCCCCCCCEECCCCHHCCCCCEEEECCCEEEEEECCCCEEEEEEEECCCCEEE
LDANHPLAGQNLTFEIELVEIV
EECCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]