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The map label for this gene is pkn1 [H]

Identifier: 119358031

GI number: 119358031

Start: 2585800

End: 2586588

Strand: Reverse

Name: pkn1 [H]

Synonym: Cpha266_2259

Alternate gene names: 119358031

Gene position: 2586588-2585800 (Counterclockwise)

Preceding gene: 119358032

Following gene: 119358030

Centisome position: 82.54

GC content: 61.22

Gene sequence:

>789_bases
ATGAATACTCCGACACATAACGAAATCCTTACCGAACTCAAGAGACTCGCGCTCCGCCAATCCGGCAGCGATCTGCCCCC
TGTCGTCGTCAACGAACGGGACGGTTCCCCGATGGTGCTTGTTCCCGCAGGCAGTTTCACCATGGGCGACGGCCTCGACA
AAGAGAGCCCGCAGCGCACCGTCTCTCTCGAAGCGTTCTACATTTCGGTTTACGCCGTCACCAACCGCCAGTACCGGGCG
TTCGTACAGGCTACGGGCCATAGGCCTCCCAACATCGGAGCAAGGATCGACTCGCTTTCAGTCTGGCACGAAGACGGCTG
TCCCGAAGAGTTCGACGATTACCCGGTGGTGCTGATCAACTGGGACGACGCGGAGGCCTACGCCCGGTGGGCGGGATGCC
GATTGCCCACGGAAGCCGAGTGGGAAAAGGCGGCGCGAGGGCCGGAAGGACATATCTACCCGTGGGGAGACCGGTGGGAC
GAAAACAATTGTCGGCACCGGAACAACAGGGGAGCGGATTCGGTAGCCCCGGTCTACGCCTATCCCGAAGGGGTCTCCGG
CTACGGCACCTGGAACCAGAGCGGCAACGTCATGGAGTGGTGCAGCGTCTGGCACGACGAAACCGATTCCGCAAACACCG
CTTCATCCGGTGAAGAGACACTCCGCCAGGAACGGGGCGGCTGCTGGCGCTATCCCGACAAATTCGCCTTCCGCTCTTCG
CAGCGCTCGTTCGTGGTTTCCAAAGCCGTCAACGATTTCCGTGGATTCCGGCTGGTGTTGCCTGTGTAG

Upstream 100 bases:

>100_bases
AGCATATCGAACAACTCAGGCAGATGGTCGTTAGCGGACAGGCGCGCAACGCCTCCGACGACCGGAATGCCTTGGCCTCT
TCGCAGAAATAAATAGCACG

Downstream 100 bases:

>100_bases
GCGGGCTCATAATCAATTCGGAAATCAGAGTGATCAGAACCCAGAACTAAAAAAGCTTGCCGTGCTTTGTCTGTAATCGT
ATATTTGTTATTTGTAAAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNTPTHNEILTELKRLALRQSGSDLPPVVVNERDGSPMVLVPAGSFTMGDGLDKESPQRTVSLEAFYISVYAVTNRQYRA
FVQATGHRPPNIGARIDSLSVWHEDGCPEEFDDYPVVLINWDDAEAYARWAGCRLPTEAEWEKAARGPEGHIYPWGDRWD
ENNCRHRNNRGADSVAPVYAYPEGVSGYGTWNQSGNVMEWCSVWHDETDSANTASSGEETLRQERGGCWRYPDKFAFRSS
QRSFVVSKAVNDFRGFRLVLPV

Sequences:

>Translated_262_residues
MNTPTHNEILTELKRLALRQSGSDLPPVVVNERDGSPMVLVPAGSFTMGDGLDKESPQRTVSLEAFYISVYAVTNRQYRA
FVQATGHRPPNIGARIDSLSVWHEDGCPEEFDDYPVVLINWDDAEAYARWAGCRLPTEAEWEKAARGPEGHIYPWGDRWD
ENNCRHRNNRGADSVAPVYAYPEGVSGYGTWNQSGNVMEWCSVWHDETDSANTASSGEETLRQERGGCWRYPDKFAFRSS
QRSFVVSKAVNDFRGFRLVLPV
>Mature_262_residues
MNTPTHNEILTELKRLALRQSGSDLPPVVVNERDGSPMVLVPAGSFTMGDGLDKESPQRTVSLEAFYISVYAVTNRQYRA
FVQATGHRPPNIGARIDSLSVWHEDGCPEEFDDYPVVLINWDDAEAYARWAGCRLPTEAEWEKAARGPEGHIYPWGDRWD
ENNCRHRNNRGADSVAPVYAYPEGVSGYGTWNQSGNVMEWCSVWHDETDSANTASSGEETLRQERGGCWRYPDKFAFRSS
QRSFVVSKAVNDFRGFRLVLPV

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth. Phosphorylates incG, a inclusion-membrane protein required for the modification of the nascent chlamydial inclusio

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=270, Percent_Identity=32.2222222222222, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI38202250, Length=295, Percent_Identity=30.1694915254237, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI257470977, Length=289, Percent_Identity=31.8339100346021, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI194248087, Length=228, Percent_Identity=31.140350877193, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI194248088, Length=243, Percent_Identity=29.2181069958848, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI194248090, Length=194, Percent_Identity=29.8969072164948, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI226437577, Length=127, Percent_Identity=36.2204724409449, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20130397, Length=248, Percent_Identity=29.8387096774194, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 29551; Mature: 29551

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPTHNEILTELKRLALRQSGSDLPPVVVNERDGSPMVLVPAGSFTMGDGLDKESPQRT
CCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEECCCEECCCCCCCCCCCCE
VSLEAFYISVYAVTNRQYRAFVQATGHRPPNIGARIDSLSVWHEDGCPEEFDDYPVVLIN
EEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCCEECCEEEECCCCCCCCCCCCCEEEEE
WDDAEAYARWAGCRLPTEAEWEKAARGPEGHIYPWGDRWDENNCRHRNNRGADSVAPVYA
CCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEE
YPEGVSGYGTWNQSGNVMEWCSVWHDETDSANTASSGEETLRQERGGCWRYPDKFAFRSS
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCC
QRSFVVSKAVNDFRGFRLVLPV
CCHHHHHHHHHHHCCEEEEECC
>Mature Secondary Structure
MNTPTHNEILTELKRLALRQSGSDLPPVVVNERDGSPMVLVPAGSFTMGDGLDKESPQRT
CCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEECCCEECCCCCCCCCCCCE
VSLEAFYISVYAVTNRQYRAFVQATGHRPPNIGARIDSLSVWHEDGCPEEFDDYPVVLIN
EEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCCEECCEEEECCCCCCCCCCCCCEEEEE
WDDAEAYARWAGCRLPTEAEWEKAARGPEGHIYPWGDRWDENNCRHRNNRGADSVAPVYA
CCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEE
YPEGVSGYGTWNQSGNVMEWCSVWHDETDSANTASSGEETLRQERGGCWRYPDKFAFRSS
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCC
QRSFVVSKAVNDFRGFRLVLPV
CCHHHHHHHHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136; 14500499 [H]