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The map label for this gene is 119357984

Identifier: 119357984

GI number: 119357984

Start: 2533264

End: 2534259

Strand: Direct

Name: 119357984

Synonym: Cpha266_2203

Alternate gene names: NA

Gene position: 2533264-2534259 (Clockwise)

Preceding gene: 119357983

Following gene: 119357988

Centisome position: 80.83

GC content: 38.55

Gene sequence:

>996_bases
ATGGTTGTCATTGCTACACTGTTTACAACTGCAGTTACGTATGGTGATGACAATGTAAACAGTGGAAATCAAAAAATTGA
CGCCAATGATTATCTCGGAGCCATAGCTGACTTAACGAAAGCCATTGCTATCGATGCAAAAAATGCACAGGCATATCATG
ATCGCGGATATGCAAAAAAGTCCATGAGAGATTATTCTGGCGCAATAGATGATTACACAAAAGCAATATCGCTTAATTCT
AATTTTTCTGCTGCTTATATAAATAGAGGCTATGTCAAGGATGCAACAGGTGATTATTCCGGAGCCATTGAAGACTATAC
GAAGGCATTACAGATTAATCCGAAAGAAGCTTTGGCCTATGTAAATCGAGGACTTTCAAAAGACAGTATTGGAGACCTGC
CGGGAGCTATAGCTGATTATACGAAAGCTATAGAGATTGATCCGAAAAATGCACCTGCCTATGTAAATCGAGGAATTACA
ACAGCTAAAATCGGTACTTTTCAGAACGCCTCAGCCGACTTCACAAAAGCTATTGAACTTCAACCGAACATGATTCAAGC
ATTCAATAATCGGGGAAGAGCAAAAATGCTCATGAAAGATCTGTCTGGCGCCATAGCGGATTTTACAAAAGCTATAGAGA
TTGATCCGAAAAATCCAATCGGTTATTTTAATCGGGGGAGTGCAAATTCAGTTATAATCCTGCGAGATAAAACGGATGCC
ATCACTGATTTTTCCAAAGCCATTGAACTTGATCCAAATTTTGCTGCAGCTTATACTGGCCGAGGGAATGCCAGAATTAT
GAGCGGCGATATAAATGGAGGAATAGCTGACATGACAACAGTGATAAAGCTTAATCCAAACGATGCTTCTGCATATTACA
ATAGAGGTGCTTTTAAAATTTTAAATAACGATAAAAATAGTGCTTTAGCTGATTTTAACAAAGCGATAGAGCTTGATCCG
AAAAATGCAGAAATGTACAAACTGCTTATGGAGTAA

Upstream 100 bases:

>100_bases
TCAAGTTACCAACTTAAACACACCCCCTTTTTGTTTTTCGCTTGGGGGGCCACATAAAAACGAAAGGAAACCAGTGAAAA
TAATTTCTCGTTATCTTTTT

Downstream 100 bases:

>100_bases
CTTTAGAATTCTGAAAAATGTACGCTAACAATAAAAAGATCCTTCCCCTTATTCGTCGGCACTCCCAACCGCCTTCCGGT
TTCGGCCATCGATAAACCAT

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MVVIATLFTTAVTYGDDNVNSGNQKIDANDYLGAIADLTKAIAIDAKNAQAYHDRGYAKKSMRDYSGAIDDYTKAISLNS
NFSAAYINRGYVKDATGDYSGAIEDYTKALQINPKEALAYVNRGLSKDSIGDLPGAIADYTKAIEIDPKNAPAYVNRGIT
TAKIGTFQNASADFTKAIELQPNMIQAFNNRGRAKMLMKDLSGAIADFTKAIEIDPKNPIGYFNRGSANSVIILRDKTDA
ITDFSKAIELDPNFAAAYTGRGNARIMSGDINGGIADMTTVIKLNPNDASAYYNRGAFKILNNDKNSALADFNKAIELDP
KNAEMYKLLME

Sequences:

>Translated_331_residues
MVVIATLFTTAVTYGDDNVNSGNQKIDANDYLGAIADLTKAIAIDAKNAQAYHDRGYAKKSMRDYSGAIDDYTKAISLNS
NFSAAYINRGYVKDATGDYSGAIEDYTKALQINPKEALAYVNRGLSKDSIGDLPGAIADYTKAIEIDPKNAPAYVNRGIT
TAKIGTFQNASADFTKAIELQPNMIQAFNNRGRAKMLMKDLSGAIADFTKAIEIDPKNPIGYFNRGSANSVIILRDKTDA
ITDFSKAIELDPNFAAAYTGRGNARIMSGDINGGIADMTTVIKLNPNDASAYYNRGAFKILNNDKNSALADFNKAIELDP
KNAEMYKLLME
>Mature_331_residues
MVVIATLFTTAVTYGDDNVNSGNQKIDANDYLGAIADLTKAIAIDAKNAQAYHDRGYAKKSMRDYSGAIDDYTKAISLNS
NFSAAYINRGYVKDATGDYSGAIEDYTKALQINPKEALAYVNRGLSKDSIGDLPGAIADYTKAIEIDPKNAPAYVNRGIT
TAKIGTFQNASADFTKAIELQPNMIQAFNNRGRAKMLMKDLSGAIADFTKAIEIDPKNPIGYFNRGSANSVIILRDKTDA
ITDFSKAIELDPNFAAAYTGRGNARIMSGDINGGIADMTTVIKLNPNDASAYYNRGAFKILNNDKNSALADFNKAIELDP
KNAEMYKLLME

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI310110582, Length=313, Percent_Identity=27.7955271565495, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI310131789, Length=313, Percent_Identity=27.7955271565495, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI310123097, Length=313, Percent_Identity=27.7955271565495, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI32307148, Length=291, Percent_Identity=29.8969072164948, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI32307150, Length=291, Percent_Identity=29.8969072164948, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI170784867, Length=244, Percent_Identity=25.4098360655738, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI296531396, Length=162, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI225735593, Length=263, Percent_Identity=26.2357414448669, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI225735591, Length=263, Percent_Identity=26.2357414448669, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI5803181, Length=104, Percent_Identity=36.5384615384615, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI167466177, Length=244, Percent_Identity=23.7704918032787, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI167466175, Length=244, Percent_Identity=23.7704918032787, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI24308141, Length=130, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI21450645, Length=205, Percent_Identity=22.9268292682927, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=290, Percent_Identity=28.9655172413793, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115532692, Length=284, Percent_Identity=29.2253521126761, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17563052, Length=230, Percent_Identity=23.9130434782609, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319387, Length=190, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17647755, Length=291, Percent_Identity=29.8969072164948, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24585827, Length=291, Percent_Identity=29.8969072164948, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24585829, Length=291, Percent_Identity=29.8969072164948, Blast_Score=100, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 35852; Mature: 35852

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVIATLFTTAVTYGDDNVNSGNQKIDANDYLGAIADLTKAIAIDAKNAQAYHDRGYAKK
CEEEEEEHHHHEECCCCCCCCCCCEECCHHHHHHHHHHHHHHEEECCCCHHHHHCCHHHH
SMRDYSGAIDDYTKAISLNSNFSAAYINRGYVKDATGDYSGAIEDYTKALQINPKEALAY
HHHHHCCCHHHHHHEEEECCCCCEEEEECCEEECCCCCCCCCHHHHHHHEECCHHHHHHH
VNRGLSKDSIGDLPGAIADYTKAIEIDPKNAPAYVNRGITTAKIGTFQNASADFTKAIEL
HHCCCCCCCCCCCCCHHHHHCEEEEECCCCCCHHHHCCEEEEEECCCCCCCCCCEEEEEC
QPNMIQAFNNRGRAKMLMKDLSGAIADFTKAIEIDPKNPIGYFNRGSANSVIILRDKTDA
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCEEEEEECCCHH
ITDFSKAIELDPNFAAAYTGRGNARIMSGDINGGIADMTTVIKLNPNDASAYYNRGAFKI
HHHHHHHEECCCCEEEEEECCCCCEEEECCCCCCCCCEEEEEEECCCCCHHHHCCCEEEE
LNNDKNSALADFNKAIELDPKNAEMYKLLME
ECCCCCCHHHHCCCEEEECCCCHHHHHHHCC
>Mature Secondary Structure
MVVIATLFTTAVTYGDDNVNSGNQKIDANDYLGAIADLTKAIAIDAKNAQAYHDRGYAKK
CEEEEEEHHHHEECCCCCCCCCCCEECCHHHHHHHHHHHHHHEEECCCCHHHHHCCHHHH
SMRDYSGAIDDYTKAISLNSNFSAAYINRGYVKDATGDYSGAIEDYTKALQINPKEALAY
HHHHHCCCHHHHHHEEEECCCCCEEEEECCEEECCCCCCCCCHHHHHHHEECCHHHHHHH
VNRGLSKDSIGDLPGAIADYTKAIEIDPKNAPAYVNRGITTAKIGTFQNASADFTKAIEL
HHCCCCCCCCCCCCCHHHHHCEEEEECCCCCCHHHHCCEEEEEECCCCCCCCCCEEEEEC
QPNMIQAFNNRGRAKMLMKDLSGAIADFTKAIEIDPKNPIGYFNRGSANSVIILRDKTDA
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCEEEEEECCCHH
ITDFSKAIELDPNFAAAYTGRGNARIMSGDINGGIADMTTVIKLNPNDASAYYNRGAFKI
HHHHHHHEECCCCEEEEEECCCCCEEEECCCCCCCCCEEEEEEECCCCCHHHHCCCEEEE
LNNDKNSALADFNKAIELDPKNAEMYKLLME
ECCCCCCHHHHCCCEEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]