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The map label for this gene is surE

Identifier: 119357826

GI number: 119357826

Start: 2353360

End: 2354136

Strand: Direct

Name: surE

Synonym: Cpha266_2034

Alternate gene names: 119357826

Gene position: 2353360-2354136 (Clockwise)

Preceding gene: 119357825

Following gene: 119357827

Centisome position: 75.09

GC content: 49.68

Gene sequence:

>777_bases
GTGGATCAACTGAAAAAGCCTCATATTCTGCTGTGCAACGATGACGGCATTGAAGGAGAAGGCCTGCATGCGCTTGCCGC
TTCCATGAAAAAAATAGGTAACATAACCGTCGTGGCACCGGCTGAACCGCATAGCGGCATGAGCCACGCCATGACGCTCG
GCACCCCCCTTCGAATAAAAAAATATTATAAAAACAACCGGTTTTTCGGCTATACCGTATCGGGAACGCCCGTTGACTGC
GTAAAAGTAGCATTAAGCCAGATACTCCCGTCGAAACCCGATCTGCTCGTCTCCGGCATCAATTACGGCAGCAACACAGC
AACGAATACACTCTATTCAGGAACCGTTGCCGCAGCTCTCGAAGGAGCAATTCAGGGCATTACCTCGCTTGCGTTTTCTC
TGGCAACCTATGAAAATGCCGATTTCTCCTATGCGGCAAAATTTGCCCGAAAACTCTCGAAAAAAGTATTAACCGAAGGA
CTGCCGCCGGATACGATTCTCTCCGTGAACATTCCAAACATCCCGGAATCGGAAATCCAGGGCATTCTGGTTACCGAACA
GGGCCGATCGCGATGGGAAGAGGACGCTATCGAGCGGCATGACGTTTACGGCAACCCCTATTACTGGCTGAACGGCACCC
TGATGCTCCTCGATACATCGCTTCAACATGACGAGTACGCAGTCAGAAAGCATTACGTTGCCGTAACTCCGATATCATGC
GATTTTACAAACAGGGATTTCATGGGATCCCTGGAACAATGGAACCTGAAAAAATAG

Upstream 100 bases:

>100_bases
ACTCTATTTCAGTCTGGGACATGATTTTTGAACGAAACTTTTTCTTACTATGGTTCACCGACAGATACGGTTTTTTGCAT
AACCCCCATACCCCCATGTT

Downstream 100 bases:

>100_bases
ACTATTGAACACTTTTTTACTCGATTATCGCCAGATCCGGACGCCGAAAAAAGGATTTTCCGGGATTTTCCGGGACTACG
TTTCAGACGGACACGAGAGA

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MDQLKKPHILLCNDDGIEGEGLHALAASMKKIGNITVVAPAEPHSGMSHAMTLGTPLRIKKYYKNNRFFGYTVSGTPVDC
VKVALSQILPSKPDLLVSGINYGSNTATNTLYSGTVAAALEGAIQGITSLAFSLATYENADFSYAAKFARKLSKKVLTEG
LPPDTILSVNIPNIPESEIQGILVTEQGRSRWEEDAIERHDVYGNPYYWLNGTLMLLDTSLQHDEYAVRKHYVAVTPISC
DFTNRDFMGSLEQWNLKK

Sequences:

>Translated_258_residues
MDQLKKPHILLCNDDGIEGEGLHALAASMKKIGNITVVAPAEPHSGMSHAMTLGTPLRIKKYYKNNRFFGYTVSGTPVDC
VKVALSQILPSKPDLLVSGINYGSNTATNTLYSGTVAAALEGAIQGITSLAFSLATYENADFSYAAKFARKLSKKVLTEG
LPPDTILSVNIPNIPESEIQGILVTEQGRSRWEEDAIERHDVYGNPYYWLNGTLMLLDTSLQHDEYAVRKHYVAVTPISC
DFTNRDFMGSLEQWNLKK
>Mature_258_residues
MDQLKKPHILLCNDDGIEGEGLHALAASMKKIGNITVVAPAEPHSGMSHAMTLGTPLRIKKYYKNNRFFGYTVSGTPVDC
VKVALSQILPSKPDLLVSGINYGSNTATNTLYSGTVAAALEGAIQGITSLAFSLATYENADFSYAAKFARKLSKKVLTEG
LPPDTILSVNIPNIPESEIQGILVTEQGRSRWEEDAIERHDVYGNPYYWLNGTLMLLDTSLQHDEYAVRKHYVAVTPISC
DFTNRDFMGSLEQWNLKK

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=249, Percent_Identity=34.5381526104418, Blast_Score=147, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_CHLPD (A1BI19)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_912470.1
- ProteinModelPortal:   A1BI19
- SMR:   A1BI19
- STRING:   A1BI19
- GeneID:   4569154
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_2034
- NMPDR:   fig|290317.7.peg.2149
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   SINVIYS
- ProtClustDB:   PRK13932
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 28387; Mature: 28387

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLKKPHILLCNDDGIEGEGLHALAASMKKIGNITVVAPAEPHSGMSHAMTLGTPLRIK
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCHHEECCCCHHHH
KYYKNNRFFGYTVSGTPVDCVKVALSQILPSKPDLLVSGINYGSNTATNTLYSGTVAAAL
HHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEECCHHHHHH
EGAIQGITSLAFSLATYENADFSYAAKFARKLSKKVLTEGLPPDTILSVNIPNIPESEIQ
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCC
GILVTEQGRSRWEEDAIERHDVYGNPYYWLNGTLMLLDTSLQHDEYAVRKHYVAVTPISC
EEEEECCCHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCHHHHHHEEEEEEEEEC
DFTNRDFMGSLEQWNLKK
CCCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MDQLKKPHILLCNDDGIEGEGLHALAASMKKIGNITVVAPAEPHSGMSHAMTLGTPLRIK
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCHHEECCCCHHHH
KYYKNNRFFGYTVSGTPVDCVKVALSQILPSKPDLLVSGINYGSNTATNTLYSGTVAAAL
HHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEECCHHHHHH
EGAIQGITSLAFSLATYENADFSYAAKFARKLSKKVLTEGLPPDTILSVNIPNIPESEIQ
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCC
GILVTEQGRSRWEEDAIERHDVYGNPYYWLNGTLMLLDTSLQHDEYAVRKHYVAVTPISC
EEEEECCCHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCHHHHHHEEEEEEEEEC
DFTNRDFMGSLEQWNLKK
CCCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA