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The map label for this gene is galE [H]

Identifier: 119357786

GI number: 119357786

Start: 2308248

End: 2309231

Strand: Reverse

Name: galE [H]

Synonym: Cpha266_1993

Alternate gene names: 119357786

Gene position: 2309231-2308248 (Counterclockwise)

Preceding gene: 119357787

Following gene: 119357785

Centisome position: 73.69

GC content: 50.41

Gene sequence:

>984_bases
ATGCGTATTCTTGTGATCGGCGGAGCGGGATATATCGGCAGTCACGTTACCAGGTCATTTCTTGATCGAGGCTATCGGGT
AACGGTTTTCGATAACCTTTCGTCGGGGTTGAGAGAAAATCTTTTTCAGGAGGCCGAGTTTGTTCATGGCGATATCATGC
AGCCTATGCAACTGCGCTCGGTCATGGCGGGCGGTTTCGACGGTTGTGTTCATCTTGCGGCGCTCAAGGCGGCCGGTCAA
TCAATGCAGCAACCGGAGATGTATGCGGAGGCCAATCTTTCAGGCACCATCAATATTTTGAACGCAGCTTCGGCAACGGG
GTTGAAGAATATTGTGTTTTCTTCTTCAGCGGCGGTTTTCGGCAATCCGCAATACCTGCCTATTGATGAAGAGCATCCGA
AGGAGCCGGTGAATTTTTACGGCTTTACAAAACTGGAAATCGAACGTCTGCTTGCATGGTTCGATCAGTTGAAAAATATC
AATTATGCAGCGTTGCGGTATTTCAATGCTGCCGGTTACGATGTTCGCGGACGTGTTTCGGGTCTGGAAAGAAATCCGGA
GAACCTTCTGCCTGTCGTGATGGAGGTTGCCGCAGGCATCCGTTCGCGATTATCGATTTTCGGGCATGATTATCCGACGA
GGGATGGCTCCTGTATCAGGGATTATGTCCATGTGAGCGATCTTGCCGAGGCCCATGTCACAGCATTTGAATCGATCAGC
AAGCATAATTTAAGCCTTGCAGTGAACCTTGGCAGCGAAACTGGCATCAGCGTGCTTGAAATGGTGGAGCGTGCCCGACT
GTTGACCGGCAGGCCCATTCCTGCCGATATTGTCGGGCGCAGGGCAGGAGATCCTCCGGATCTCGTTGCGTCATCCGAAA
AAGCGCGTAAACTCCTTGGATGGTTACCGCAATACAGTGACATTGATACGTTGATATTATCGACATGGCGTGCATATGAA
AAAGCTTTGAAGATTCAGCCCTGA

Upstream 100 bases:

>100_bases
AGAACAGGTGAAGGTTTGTGTTTGCTGGTTGTCTGTTTCGGTAGAATGGTGTTAAAGCATTGGTTTGCAGTGGGTGTTCC
AACTTTTTTATGAGGTTATT

Downstream 100 bases:

>100_bases
ATGTTTTCATGCCCGATTTTGATGCCACTTTTTCCGGATTGAGTTTCGCCATGAAAACGTGTTGGCGGGAAATCTATCCG
GGGAAGCCCAGGGAGAAGCG

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MRILVIGGAGYIGSHVTRSFLDRGYRVTVFDNLSSGLRENLFQEAEFVHGDIMQPMQLRSVMAGGFDGCVHLAALKAAGQ
SMQQPEMYAEANLSGTINILNAASATGLKNIVFSSSAAVFGNPQYLPIDEEHPKEPVNFYGFTKLEIERLLAWFDQLKNI
NYAALRYFNAAGYDVRGRVSGLERNPENLLPVVMEVAAGIRSRLSIFGHDYPTRDGSCIRDYVHVSDLAEAHVTAFESIS
KHNLSLAVNLGSETGISVLEMVERARLLTGRPIPADIVGRRAGDPPDLVASSEKARKLLGWLPQYSDIDTLILSTWRAYE
KALKIQP

Sequences:

>Translated_327_residues
MRILVIGGAGYIGSHVTRSFLDRGYRVTVFDNLSSGLRENLFQEAEFVHGDIMQPMQLRSVMAGGFDGCVHLAALKAAGQ
SMQQPEMYAEANLSGTINILNAASATGLKNIVFSSSAAVFGNPQYLPIDEEHPKEPVNFYGFTKLEIERLLAWFDQLKNI
NYAALRYFNAAGYDVRGRVSGLERNPENLLPVVMEVAAGIRSRLSIFGHDYPTRDGSCIRDYVHVSDLAEAHVTAFESIS
KHNLSLAVNLGSETGISVLEMVERARLLTGRPIPADIVGRRAGDPPDLVASSEKARKLLGWLPQYSDIDTLILSTWRAYE
KALKIQP
>Mature_327_residues
MRILVIGGAGYIGSHVTRSFLDRGYRVTVFDNLSSGLRENLFQEAEFVHGDIMQPMQLRSVMAGGFDGCVHLAALKAAGQ
SMQQPEMYAEANLSGTINILNAASATGLKNIVFSSSAAVFGNPQYLPIDEEHPKEPVNFYGFTKLEIERLLAWFDQLKNI
NYAALRYFNAAGYDVRGRVSGLERNPENLLPVVMEVAAGIRSRLSIFGHDYPTRDGSCIRDYVHVSDLAEAHVTAFESIS
KHNLSLAVNLGSETGISVLEMVERARLLTGRPIPADIVGRRAGDPPDLVASSEKARKLLGWLPQYSDIDTLILSTWRAYE
KALKIQP

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=333, Percent_Identity=39.6396396396396, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI56118217, Length=333, Percent_Identity=39.6396396396396, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI189083684, Length=333, Percent_Identity=39.6396396396396, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=26.3492063492064, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI193211614, Length=244, Percent_Identity=26.6393442622951, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI8393516, Length=244, Percent_Identity=26.6393442622951, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786974, Length=328, Percent_Identity=36.890243902439, Blast_Score=205, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI71982035, Length=321, Percent_Identity=36.1370716510903, Blast_Score=181, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71982038, Length=323, Percent_Identity=35.9133126934984, Blast_Score=180, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17539532, Length=325, Percent_Identity=24.9230769230769, Blast_Score=81, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=321, Percent_Identity=37.6947040498442, Blast_Score=193, Evalue=3e-50,
Organism=Drosophila melanogaster, GI19923002, Length=337, Percent_Identity=38.8724035608309, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI21356223, Length=317, Percent_Identity=25.8675078864353, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36001; Mature: 36001

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVIGGAGYIGSHVTRSFLDRGYRVTVFDNLSSGLRENLFQEAEFVHGDIMQPMQLRS
CEEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VMAGGFDGCVHLAALKAAGQSMQQPEMYAEANLSGTINILNAASATGLKNIVFSSSAAVF
HHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEECCCCCCHHHHHHCCCCEEC
GNPQYLPIDEEHPKEPVNFYGFTKLEIERLLAWFDQLKNINYAALRYFNAAGYDVRGRVS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCCCHHCC
GLERNPENLLPVVMEVAAGIRSRLSIFGHDYPTRDGSCIRDYVHVSDLAEAHVTAFESIS
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KHNLSLAVNLGSETGISVLEMVERARLLTGRPIPADIVGRRAGDPPDLVASSEKARKLLG
HCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHCCCHHHHHHHH
WLPQYSDIDTLILSTWRAYEKALKIQP
CCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRILVIGGAGYIGSHVTRSFLDRGYRVTVFDNLSSGLRENLFQEAEFVHGDIMQPMQLRS
CEEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VMAGGFDGCVHLAALKAAGQSMQQPEMYAEANLSGTINILNAASATGLKNIVFSSSAAVF
HHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEECCCCCCHHHHHHCCCCEEC
GNPQYLPIDEEHPKEPVNFYGFTKLEIERLLAWFDQLKNINYAALRYFNAAGYDVRGRVS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCCCHHCC
GLERNPENLLPVVMEVAAGIRSRLSIFGHDYPTRDGSCIRDYVHVSDLAEAHVTAFESIS
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KHNLSLAVNLGSETGISVLEMVERARLLTGRPIPADIVGRRAGDPPDLVASSEKARKLLG
HCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHCCCHHHHHHHH
WLPQYSDIDTLILSTWRAYEKALKIQP
CCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]