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The map label for this gene is paaK [H]

Identifier: 119357761

GI number: 119357761

Start: 2283428

End: 2284729

Strand: Direct

Name: paaK [H]

Synonym: Cpha266_1968

Alternate gene names: 119357761

Gene position: 2283428-2284729 (Clockwise)

Preceding gene: 119357760

Following gene: 119357762

Centisome position: 72.86

GC content: 51.31

Gene sequence:

>1302_bases
ATGATCTGGAACAAACATTACGAGTGCATGGAGCGGGAAGAGCTCCGAAAGCTTCAAGGAGAGCGGCTCAGAGAAATGGT
GCAGAGGGTTTACGACAAAGTGCCCTTTTACCGTAAAAAGTTACAGGATACCGGCATAGAACCCGGAGATATTCGAAACA
TCGAAGATCTGAATAAACTGCCGTTCACGACCAAACAGGATCTCCGGGACAACTACCCGTTCGGGCTTTTTACCGTTCCG
CAGCACGACATTGTCCGACTGCACGCATCGAGCGGCACAACCGGAAAATCAACCGTGGTAGGATACACCCATAACGACAT
CAGTATGTGGACCGAAGTGGTAGCTCGATCGCTTACCATGGCGGGAGTGACTAATTCCGATATCGTGCAGATCGCCTACG
GGTACGGACTGTTTACCGGCGGCCTCGGCGTACACTACGGCGCTGAAAAAGTCGGAGCGTCGGTTATACCAATTTCAGGC
GGCAATACCAAAAAGCAGTTGCAACTCATGGAGGATTTCGGATCCACGGCCCTTGCCTGCACCCCTTCCTATGCGGCCTT
TCTTGGCGAGGCTCTGGTTGAAGAACAGATTGATCGTAAAAAGATCAGACTTAAAGCCGGCATTTTCGGTGCGGAACCTT
GGACGGAAGAGATGCGTACGCAGATCCAGAACCTTCTCGGCATCAAAGCATACGATATTTACGGACTCAGCGAAATCATC
GGGCCAGGAGTTTCGATGGAGTGTCGCTGCCAGAATGGCATGCACATTTTTGAAGATCACTTTATTCCTGAAATCATCAA
CCCCGATACCTGCGAAGTACTTCCTTACGGTGAACTGGGAGAACTGGTTTTTACCCCTGCAACAAAGGAAGCCATGCCGC
TTGTGCGTTACCGAACGCGCGACCTGACGCGACTGCATCCGGAAAAATGCGACTGCGGCCGCACGCTGGTACGAATGGAA
AAGTGCGTTGGACGTTCTGACGATATGCTCATCATCCGGGGCGTCAACGTATTTCCGTCACAGGTGGAATCGGTCCTGCT
TGAAATGAGCGAAACAAAACCGCACTACCTGCTGGTCGTCAGCCGTGAAAACAACCTCGACACCCTTGAAATCCAGGTTG
AAGTCGAACCCCAGTTTTTTTCGGACGAGGTGAAGGAGCTTGAAGGGCTGCGTAAAAGAATTCATGCCAATATCTCAAGT
ATCCTCGGCATCAGCGCATCGATACGGCTGGTGGAACCCAACACCATTGAACGCAGTATGGGAAAAGCCCAGCGCGTCGT
AGATAAACGAAAACTCACCTAA

Upstream 100 bases:

>100_bases
CACTTTTTCAGGCAAAAGGCAGCGATATGGTTGCCATGAACATCAATGCATTCAGAAAAGGAGAGGCAATATCTCTATCT
CAACATCAAGCGACGACCTC

Downstream 100 bases:

>100_bases
GGGATTTGGTAAATACTAAAATACCTCTTATTATGTTTTCATAGAGCAACGTTTAAGCAGGAGAAATTGCATATGAAAAC
ATCTGTACTGAGCCGAAATA

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MIWNKHYECMEREELRKLQGERLREMVQRVYDKVPFYRKKLQDTGIEPGDIRNIEDLNKLPFTTKQDLRDNYPFGLFTVP
QHDIVRLHASSGTTGKSTVVGYTHNDISMWTEVVARSLTMAGVTNSDIVQIAYGYGLFTGGLGVHYGAEKVGASVIPISG
GNTKKQLQLMEDFGSTALACTPSYAAFLGEALVEEQIDRKKIRLKAGIFGAEPWTEEMRTQIQNLLGIKAYDIYGLSEII
GPGVSMECRCQNGMHIFEDHFIPEIINPDTCEVLPYGELGELVFTPATKEAMPLVRYRTRDLTRLHPEKCDCGRTLVRME
KCVGRSDDMLIIRGVNVFPSQVESVLLEMSETKPHYLLVVSRENNLDTLEIQVEVEPQFFSDEVKELEGLRKRIHANISS
ILGISASIRLVEPNTIERSMGKAQRVVDKRKLT

Sequences:

>Translated_433_residues
MIWNKHYECMEREELRKLQGERLREMVQRVYDKVPFYRKKLQDTGIEPGDIRNIEDLNKLPFTTKQDLRDNYPFGLFTVP
QHDIVRLHASSGTTGKSTVVGYTHNDISMWTEVVARSLTMAGVTNSDIVQIAYGYGLFTGGLGVHYGAEKVGASVIPISG
GNTKKQLQLMEDFGSTALACTPSYAAFLGEALVEEQIDRKKIRLKAGIFGAEPWTEEMRTQIQNLLGIKAYDIYGLSEII
GPGVSMECRCQNGMHIFEDHFIPEIINPDTCEVLPYGELGELVFTPATKEAMPLVRYRTRDLTRLHPEKCDCGRTLVRME
KCVGRSDDMLIIRGVNVFPSQVESVLLEMSETKPHYLLVVSRENNLDTLEIQVEVEPQFFSDEVKELEGLRKRIHANISS
ILGISASIRLVEPNTIERSMGKAQRVVDKRKLT
>Mature_433_residues
MIWNKHYECMEREELRKLQGERLREMVQRVYDKVPFYRKKLQDTGIEPGDIRNIEDLNKLPFTTKQDLRDNYPFGLFTVP
QHDIVRLHASSGTTGKSTVVGYTHNDISMWTEVVARSLTMAGVTNSDIVQIAYGYGLFTGGLGVHYGAEKVGASVIPISG
GNTKKQLQLMEDFGSTALACTPSYAAFLGEALVEEQIDRKKIRLKAGIFGAEPWTEEMRTQIQNLLGIKAYDIYGLSEII
GPGVSMECRCQNGMHIFEDHFIPEIINPDTCEVLPYGELGELVFTPATKEAMPLVRYRTRDLTRLHPEKCDCGRTLVRME
KCVGRSDDMLIIRGVNVFPSQVESVLLEMSETKPHYLLVVSRENNLDTLEIQVEVEPQFFSDEVKELEGLRKRIHANISS
ILGISASIRLVEPNTIERSMGKAQRVVDKRKLT

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=438, Percent_Identity=51.3698630136986, Blast_Score=435, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48949; Mature: 48949

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWNKHYECMEREELRKLQGERLREMVQRVYDKVPFYRKKLQDTGIEPGDIRNIEDLNKL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHCC
PFTTKQDLRDNYPFGLFTVPQHDIVRLHASSGTTGKSTVVGYTHNDISMWTEVVARSLTM
CCCCHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
AGVTNSDIVQIAYGYGLFTGGLGVHYGAEKVGASVIPISGGNTKKQLQLMEDFGSTALAC
CCCCCCCEEEEEECCCEEECCCCCCCCHHHHCCEEEEECCCCHHHHHHHHHHCCCCEEEE
TPSYAAFLGEALVEEQIDRKKIRLKAGIFGAEPWTEEMRTQIQNLLGIKAYDIYGLSEII
CCHHHHHHHHHHHHHHHHHHHEEHEECCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHH
GPGVSMECRCQNGMHIFEDHFIPEIINPDTCEVLPYGELGELVFTPATKEAMPLVRYRTR
CCCCCEEEEECCCCEEHHHCCCCHHCCCCCCEEECCCCCCCEEECCCCHHHHHHHHHHHH
DLTRLHPEKCDCGRTLVRMEKCVGRSDDMLIIRGVNVFPSQVESVLLEMSETKPHYLLVV
HHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEE
SRENNLDTLEIQVEVEPQFFSDEVKELEGLRKRIHANISSILGISASIRLVEPNTIERSM
ECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
GKAQRVVDKRKLT
HHHHHHHHHHCCC
>Mature Secondary Structure
MIWNKHYECMEREELRKLQGERLREMVQRVYDKVPFYRKKLQDTGIEPGDIRNIEDLNKL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHCC
PFTTKQDLRDNYPFGLFTVPQHDIVRLHASSGTTGKSTVVGYTHNDISMWTEVVARSLTM
CCCCHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
AGVTNSDIVQIAYGYGLFTGGLGVHYGAEKVGASVIPISGGNTKKQLQLMEDFGSTALAC
CCCCCCCEEEEEECCCEEECCCCCCCCHHHHCCEEEEECCCCHHHHHHHHHHCCCCEEEE
TPSYAAFLGEALVEEQIDRKKIRLKAGIFGAEPWTEEMRTQIQNLLGIKAYDIYGLSEII
CCHHHHHHHHHHHHHHHHHHHEEHEECCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHH
GPGVSMECRCQNGMHIFEDHFIPEIINPDTCEVLPYGELGELVFTPATKEAMPLVRYRTR
CCCCCEEEEECCCCEEHHHCCCCHHCCCCCCEEECCCCCCCEEECCCCHHHHHHHHHHHH
DLTRLHPEKCDCGRTLVRMEKCVGRSDDMLIIRGVNVFPSQVESVLLEMSETKPHYLLVV
HHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEE
SRENNLDTLEIQVEVEPQFFSDEVKELEGLRKRIHANISSILGISASIRLVEPNTIERSM
ECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
GKAQRVVDKRKLT
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]