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The map label for this gene is ahpC [C]

Identifier: 119357758

GI number: 119357758

Start: 2279586

End: 2280263

Strand: Direct

Name: ahpC [C]

Synonym: Cpha266_1965

Alternate gene names: 119357758

Gene position: 2279586-2280263 (Clockwise)

Preceding gene: 119357757

Following gene: 119357759

Centisome position: 72.74

GC content: 47.94

Gene sequence:

>678_bases
ATGTCCGATCACATCGATGACAACTATTACTACAATGATTCAGGAATGCCGCTGCTTGGCGACGAATTCCCTGAAATGAA
GGTACAGACCACCCATGGACCAATGAATATTCCCGGTGACCTGAAAGGTTCCTGGTTTGTTCTTTTCAGCCATCCGGCAG
ATTACACCCCGGTATGCACGACAGAGTTTCTCGCCTTTCAGGAGCGAGTAGCGGACTTTGACAAACTTGGATGCCAACTG
GTTGGCATGTCGGTTGATCAGGTTTTTTCACACATCAAGTGGGTGGAGTGGATCAAGGATAATCTCGACACTGAAATAAC
CTTCCCGATCGTTGCCGCCAATGACAGAATCGCCATGCAGCTCGGCATGCTTCATCCAGGAAAAGGGTCCAACACGGTTC
GCGCTGTCTTTGTTGGCGATCCTGATGGAAAAGTTCGTCTGATTCTTTACTATCCGCAGGAAATAGGCCGGAATATCGAT
GAAATTGTCAGAGCAGTTAAAGCGCTGCAGGTTTCCGATAAACACAAGGTTGCCATTCCGGCAAACTGGCCGATCAACTC
TCTTCTTAAAGATCGGGTCATTATTCCTCCTGCAAATAACATTGAGGATGCAAAAAAACGCCCCTCACAGTACGATTGTT
ACGATTGGTGGTTCTGCCACAAACCGCTTGAAGGCTGA

Upstream 100 bases:

>100_bases
AACAGGCCGTCATCGCGGATTTCCTGACTTAGCCGGTTCCATGCCAATCATTTTTCACTACTACCCGACAATCAAAAAAA
CATTAACAGGAGACCTATTT

Downstream 100 bases:

>100_bases
TAATCCATTTGCAAAACCTCATAGAGCCGACCGGAGTGAACATGTTCCTGTCGGCTTTTTTTGTAGTTCACACCTGACTG
ACCGTAAAGCGTAACACAAA

Product: peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSDHIDDNYYYNDSGMPLLGDEFPEMKVQTTHGPMNIPGDLKGSWFVLFSHPADYTPVCTTEFLAFQERVADFDKLGCQL
VGMSVDQVFSHIKWVEWIKDNLDTEITFPIVAANDRIAMQLGMLHPGKGSNTVRAVFVGDPDGKVRLILYYPQEIGRNID
EIVRAVKALQVSDKHKVAIPANWPINSLLKDRVIIPPANNIEDAKKRPSQYDCYDWWFCHKPLEG

Sequences:

>Translated_225_residues
MSDHIDDNYYYNDSGMPLLGDEFPEMKVQTTHGPMNIPGDLKGSWFVLFSHPADYTPVCTTEFLAFQERVADFDKLGCQL
VGMSVDQVFSHIKWVEWIKDNLDTEITFPIVAANDRIAMQLGMLHPGKGSNTVRAVFVGDPDGKVRLILYYPQEIGRNID
EIVRAVKALQVSDKHKVAIPANWPINSLLKDRVIIPPANNIEDAKKRPSQYDCYDWWFCHKPLEG
>Mature_224_residues
SDHIDDNYYYNDSGMPLLGDEFPEMKVQTTHGPMNIPGDLKGSWFVLFSHPADYTPVCTTEFLAFQERVADFDKLGCQLV
GMSVDQVFSHIKWVEWIKDNLDTEITFPIVAANDRIAMQLGMLHPGKGSNTVRAVFVGDPDGKVRLILYYPQEIGRNIDE
IVRAVKALQVSDKHKVAIPANWPINSLLKDRVIIPPANNIEDAKKRPSQYDCYDWWFCHKPLEG

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=202, Percent_Identity=37.6237623762376, Blast_Score=124, Evalue=6e-29,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=35.4285714285714, Blast_Score=104, Evalue=5e-23,
Organism=Homo sapiens, GI4505591, Length=146, Percent_Identity=39.041095890411, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32455266, Length=146, Percent_Identity=39.041095890411, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32455264, Length=146, Percent_Identity=39.041095890411, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32483377, Length=150, Percent_Identity=34, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI5802974, Length=146, Percent_Identity=34.2465753424658, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI5453549, Length=191, Percent_Identity=30.8900523560209, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI33188454, Length=58, Percent_Identity=51.7241379310345, Blast_Score=71, Evalue=7e-13,
Organism=Escherichia coli, GI1786822, Length=151, Percent_Identity=29.8013245033113, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25153706, Length=192, Percent_Identity=34.375, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17554494, Length=146, Percent_Identity=39.7260273972603, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193204376, Length=178, Percent_Identity=31.4606741573034, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32565831, Length=146, Percent_Identity=34.9315068493151, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319407, Length=213, Percent_Identity=40.8450704225352, Blast_Score=143, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6323613, Length=144, Percent_Identity=34.0277777777778, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320661, Length=144, Percent_Identity=31.25, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17975518, Length=204, Percent_Identity=38.7254901960784, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24652436, Length=204, Percent_Identity=38.7254901960784, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24652434, Length=204, Percent_Identity=38.7254901960784, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24581278, Length=178, Percent_Identity=39.3258426966292, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17738015, Length=199, Percent_Identity=30.6532663316583, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21357347, Length=146, Percent_Identity=35.6164383561644, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17157991, Length=146, Percent_Identity=34.9315068493151, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24641739, Length=146, Percent_Identity=34.9315068493151, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24656348, Length=143, Percent_Identity=32.8671328671329, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17864676, Length=143, Percent_Identity=32.8671328671329, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 25597; Mature: 25466

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDHIDDNYYYNDSGMPLLGDEFPEMKVQTTHGPMNIPGDLKGSWFVLFSHPADYTPVCT
CCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHH
TEFLAFQERVADFDKLGCQLVGMSVDQVFSHIKWVEWIKDNLDTEITFPIVAANDRIAMQ
HHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEE
LGMLHPGKGSNTVRAVFVGDPDGKVRLILYYPQEIGRNIDEIVRAVKALQVSDKHKVAIP
ECCCCCCCCCCEEEEEEEECCCCCEEEEEECCHHHCCCHHHHHHHHHHHHCCCCCEEEEE
ANWPINSLLKDRVIIPPANNIEDAKKRPSQYDCYDWWFCHKPLEG
CCCCHHHHHHCCEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
SDHIDDNYYYNDSGMPLLGDEFPEMKVQTTHGPMNIPGDLKGSWFVLFSHPADYTPVCT
CCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHH
TEFLAFQERVADFDKLGCQLVGMSVDQVFSHIKWVEWIKDNLDTEITFPIVAANDRIAMQ
HHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEE
LGMLHPGKGSNTVRAVFVGDPDGKVRLILYYPQEIGRNIDEIVRAVKALQVSDKHKVAIP
ECCCCCCCCCCEEEEEEEECCCCCEEEEEECCHHHCCCHHHHHHHHHHHHCCCCCEEEEE
ANWPINSLLKDRVIIPPANNIEDAKKRPSQYDCYDWWFCHKPLEG
CCCCHHHHHHCCEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]